DE58889T1 - Plasmid pcg1. - Google Patents

Plasmid pcg1.

Info

Publication number
DE58889T1
DE58889T1 DE198282101018T DE82101018T DE58889T1 DE 58889 T1 DE58889 T1 DE 58889T1 DE 198282101018 T DE198282101018 T DE 198282101018T DE 82101018 T DE82101018 T DE 82101018T DE 58889 T1 DE58889 T1 DE 58889T1
Authority
DE
Germany
Prior art keywords
plasmid
pcg1
plasmid pcg1
corynebacterium glutamicum
microorganism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE198282101018T
Other languages
German (de)
English (en)
Inventor
Akira Kawasaki-Shi Kanagawa-Ken Furuya
Ryoichi Machida-Shi Tokyo Katsumata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Publication of DE58889T1 publication Critical patent/DE58889T1/de
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE198282101018T 1981-02-12 1982-02-11 Plasmid pcg1. Pending DE58889T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56018101A JPS57134500A (en) 1981-02-12 1981-02-12 Plasmid pcg1

Publications (1)

Publication Number Publication Date
DE58889T1 true DE58889T1 (de) 1983-04-14

Family

ID=11962230

Family Applications (2)

Application Number Title Priority Date Filing Date
DE198282101018T Pending DE58889T1 (de) 1981-02-12 1982-02-11 Plasmid pcg1.
DE8282101018T Expired DE3274561D1 (en) 1981-02-12 1982-02-11 Plasmid pcg1

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8282101018T Expired DE3274561D1 (en) 1981-02-12 1982-02-11 Plasmid pcg1

Country Status (5)

Country Link
US (1) US4617267A (cg-RX-API-DMAC7.html)
EP (1) EP0058889B1 (cg-RX-API-DMAC7.html)
JP (1) JPS57134500A (cg-RX-API-DMAC7.html)
CA (1) CA1196588A (cg-RX-API-DMAC7.html)
DE (2) DE58889T1 (cg-RX-API-DMAC7.html)

Families Citing this family (110)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4778762A (en) * 1980-04-17 1988-10-18 Ajinomoto Company Incorporated Plasmid
JPS5877895A (ja) * 1981-11-02 1983-05-11 Ajinomoto Co Inc プラスミドphm1519
US5236831A (en) * 1981-12-29 1993-08-17 Kiowa Hakko Kogyo Co., Ltd. Amino acid synthesis in corynebacteria using E. coli genes
JPS58126789A (ja) * 1981-12-29 1983-07-28 Kyowa Hakko Kogyo Co Ltd レースレオニンの製造法
US4559308A (en) * 1983-01-27 1985-12-17 Stauffer Chemical Co. Corynebacterium plasmid and vector
JPS59156294A (ja) * 1983-02-17 1984-09-05 Kyowa Hakko Kogyo Co Ltd ヒスチジンの製造法
JPS6066989A (ja) * 1983-09-24 1985-04-17 Kyowa Hakko Kogyo Co Ltd L−アルギニンの製造法
JPS59156292A (ja) * 1983-02-17 1984-09-05 Kyowa Hakko Kogyo Co Ltd トリプトフアンの製造法
JPS59196098A (ja) * 1983-04-23 1984-11-07 Ajinomoto Co Inc 発酵法によるl−トリプトフアンの製造法
US4649119A (en) * 1983-04-28 1987-03-10 Massachusetts Institute Of Technology Cloning systems for corynebacterium
JPH0783714B2 (ja) * 1983-08-29 1995-09-13 味の素株式会社 発酵法によるl―アミノ酸の製造法
JPH06102029B2 (ja) * 1984-07-31 1994-12-14 味の素株式会社 L−トリプトフアンの製造法
GB2165546B (en) * 1984-08-21 1989-05-17 Asahi Chemical Ind A plasmid containing a gene for tetracycline resistance and dna fragments derived therefrom
DE3576523D1 (de) * 1984-11-20 1990-04-19 Ajinomoto Kk Rekombinante dna enthaltende coryneformbakterien und verfahren zur herstellung von aromatischen aminosaeuren unter verwendung dieser bakterien.
JP2967996B2 (ja) * 1989-06-06 1999-10-25 協和醗酵工業株式会社 L―トリプトファンの製造法
KR0161531B1 (ko) * 1990-03-08 1998-11-16 하야시바라 겐 락토수크로오스 고함유 분말의 제조방법과 그 분말의 용도
JP3078312B2 (ja) * 1990-11-22 2000-08-21 協和醗酵工業株式会社 物質の製造法
JPH06225776A (ja) * 1992-12-07 1994-08-16 Kyowa Hakko Kogyo Co Ltd リボフラビンの製造法
US5547864A (en) * 1993-01-13 1996-08-20 Ajinomoto Co., Inc. Coryneform bacteria deficient in a cell surface protein
JP4184606B2 (ja) * 1998-09-04 2008-11-19 協和醗酵工業株式会社 新規遺伝子
KR20070087088A (ko) 1999-06-25 2007-08-27 바스프 악티엔게젤샤프트 탄소 대사 및 에너지 생산과 관련된 단백질을 코딩하는코리네박테리움 글루타미쿰 유전자
AU783697B2 (en) 1999-07-01 2005-11-24 Paik Kwang Industrial Co., Ltd. Orynebacterium glutamicum genes encoding phosphoenolpyruvate: sugar phosphotransferase system proteins
DE1246922T1 (de) 1999-07-01 2003-03-20 Basf Ag Für proteine des phosphoenolpyruvat:zucker phosphotransferase systems kodierende gene aus corynebacterium glutamicum
PL341895A1 (en) * 1999-08-12 2001-02-26 Ajinomoto Kk Plasmide autonomously replicable in corynebacter bacteria
US6927046B1 (en) 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
JP4469568B2 (ja) 2003-07-09 2010-05-26 三菱化学株式会社 有機酸の製造方法
WO2005021770A1 (ja) 2003-08-28 2005-03-10 Mitsubishi Chemical Corporation コハク酸の製造方法
BRPI0510919A (pt) 2004-05-20 2008-05-20 Ajinomoto Kk bactéria produtora de ácido succìnico e processo para produzir ácido succìnico
EP1748062B1 (en) * 2004-05-20 2012-06-13 Ajinomoto Co., Inc. Succinic acid-producing bacterium and process for producing succinic acid
RU2416636C2 (ru) * 2004-12-06 2011-04-20 Сейдж Байосайенсиз Инк. Способ выращивания продуцирующей лизин грамположительной бактерии для доставки биологически активных соединений жвачным животным, кормовая добавка (варианты) и способ кормления жвачных животных
KR101233739B1 (ko) 2004-12-28 2013-02-18 아지노모토 가부시키가이샤 L-글루탐산 생산 미생물 및 l-글루탐산의 제조방법
WO2007046389A1 (ja) 2005-10-18 2007-04-26 Ajinomoto Co., Inc. コハク酸の製造方法
ES2382207T3 (es) 2005-12-27 2012-06-06 Kyowa Hakko Bio Co., Ltd. Procedimiento para la producción de L-glutamina
BRPI0707674A2 (pt) 2006-02-24 2011-05-10 Mitsubishi Chem Corp bactÉria capaz de produzir Ácido orgÂnico e processo para produÇço do mesmo
JP2010130899A (ja) 2007-03-14 2010-06-17 Ajinomoto Co Inc L−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法
EP2149607B1 (en) 2007-04-10 2017-12-20 Ajinomoto Co., Inc. Method for production of succinic acid
EP2149608A4 (en) 2007-04-16 2013-02-20 Ajinomoto Kk PROCESS FOR PREPARING AN ORGANIC ACID
WO2009025363A1 (ja) 2007-08-23 2009-02-26 Mitsubishi Chemical Corporation コハク酸の製造方法
BRPI0816429A2 (pt) 2007-09-04 2019-09-24 Ajinomoto Kk microorganismo, e, método para a produção de um l-aminoácido.
JP2011067095A (ja) 2008-01-10 2011-04-07 Ajinomoto Co Inc 発酵法による目的物質の製造法
US8530203B2 (en) 2008-09-01 2013-09-10 Shinshu University Process for producing useful substance
CN102272304B (zh) 2009-01-07 2013-10-23 三菱化学株式会社 切断固醇侧链的酶蛋白质及其应用
EP2400024A4 (en) 2009-02-18 2012-10-31 Univ Shinshu METHOD FOR PRODUCING A USEFUL SUBSTANCE
CA2755310A1 (en) 2009-03-30 2010-10-07 Research Institute Of Innovative Technology For The Earth Coryneform bacterium transformant and process for producing isobutanol using the same
JP2012223091A (ja) 2009-08-25 2012-11-15 Ajinomoto Co Inc L−アミノ酸の製造法
CN102834515B (zh) 2010-08-31 2016-08-03 株式会社Api 新的水解酶蛋白
KR101842518B1 (ko) 2010-09-08 2018-03-27 그린 페놀 가이하쓰 가부시키가이샤 코리네형 세균 형질 전환체 및 그것을 사용하는 페놀의 제조 방법
WO2012063862A1 (ja) 2010-11-10 2012-05-18 グリーンフェノール・高機能フェノール樹脂製造技術研究組合 コリネ型細菌形質転換体及びそれを用いるフェノールの製造方法
CA2830373A1 (en) 2011-03-18 2012-09-27 Mitsubishi Chemical Corporation Method for producing polymer, method for producing organic acid, and organic acid-producing microorganism
JP5960701B2 (ja) 2011-08-22 2016-08-02 公益財団法人地球環境産業技術研究機構 コリネ型細菌形質転換体及びそれを用いるバリンの製造方法
AU2012329967B2 (en) 2011-10-25 2015-07-23 Ajinomoto Co., Inc. Secretion production method for protein
KR101653555B1 (ko) 2011-11-02 2016-09-02 아지노모토 가부시키가이샤 단백질의 분비 생산 방법
CN103946372B (zh) 2011-11-02 2016-06-08 味之素株式会社 用于分泌产生蛋白质的方法
BR112013016373B1 (pt) 2011-11-11 2021-05-18 Ajinomoto Co., Inc método para produzir uma substância alvo
CN104379742A (zh) 2012-05-29 2015-02-25 味之素株式会社 生产3-乙酰氨基-4-羟基苯甲酸的方法
CN104487586B (zh) 2013-02-18 2017-03-08 味之素株式会社 基于沉淀的蛋白质制造方法
RU2013119826A (ru) 2013-04-29 2014-11-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Коринеформная бактерия и способ получения гетерологичных гибридных белков
WO2014185430A1 (ja) 2013-05-13 2014-11-20 味の素株式会社 L-アミノ酸の製造法
JP2016165225A (ja) 2013-07-09 2016-09-15 味の素株式会社 有用物質の製造方法
JP2016192903A (ja) 2013-09-17 2016-11-17 味の素株式会社 海藻由来バイオマスからのl−アミノ酸の製造方法
EP3061828B1 (en) 2013-10-23 2024-08-28 Ajinomoto Co., Inc. Method for producing target substance
EP3101130B1 (en) 2014-01-31 2020-05-06 Ajinomoto Co., Inc. Mutant glutamate-cysteine ligase and method for manufacturing gamma-glutamyl-valyl-glycine
JP2017216881A (ja) 2014-12-26 2017-12-14 味の素株式会社 ジカルボン酸の製造方法
KR102706404B1 (ko) 2015-05-19 2024-09-12 미쓰비시 케미컬 유케이 리미티드 메타크릴산 및 그 유도체의 생물학적 제조 방법
JP6881448B2 (ja) 2015-10-27 2021-06-02 味の素株式会社 アルデヒドの製造方法
JP6623690B2 (ja) 2015-10-30 2019-12-25 味の素株式会社 グルタミン酸系l−アミノ酸の製造法
WO2017122747A1 (en) 2016-01-12 2017-07-20 Ajinomoto Co., Inc. Method for producing benzaldehyde
KR102335301B1 (ko) 2016-10-21 2021-12-06 아지노모토 가부시키가이샤 단백질의 분비 생산법
EP3530747A4 (en) 2016-10-21 2020-07-22 Ajinomoto Co., Inc. SECRETORY PROTEIN PRODUCTION PROCESS
EP3532629A1 (en) 2016-10-26 2019-09-04 Ajinomoto Co., Inc. Method for producing objective substance
JP7063332B2 (ja) 2016-10-26 2022-05-09 味の素株式会社 目的物質の製造方法
CN109952380B (zh) 2016-10-26 2023-07-14 味之素株式会社 用于生产目标物质的方法
CN109937257B (zh) 2016-10-26 2023-06-30 味之素株式会社 生产目标物质的方法
WO2018079686A1 (en) 2016-10-26 2018-05-03 Ajinomoto Co., Inc. Method for producing l-methionine or metabolites requiring s-adenosylmethionine for synthesis
EP3532610B1 (en) 2016-10-27 2023-09-27 Ajinomoto Co., Inc. Method for producing aldehyde
GB201619827D0 (en) 2016-11-23 2017-01-04 Lucite Int Uk Ltd Process for the production of methyl methacrylate
WO2018179834A1 (en) 2017-03-28 2018-10-04 Ajinomoto Co., Inc. Method for producing rna
JP7066977B2 (ja) 2017-04-03 2022-05-16 味の素株式会社 L-アミノ酸の製造法
JP7035024B2 (ja) 2017-04-13 2022-03-14 協和発酵バイオ株式会社 テアニンの製造方法
US10858676B2 (en) 2017-05-22 2020-12-08 Ajinomoto Co., Inc. Method for producing objective substance
AU2018334768B2 (en) 2017-09-25 2024-08-08 Ajinomoto Co., Inc. Protein production method and disaccharide production method
WO2019078095A1 (en) 2017-10-16 2019-04-25 Ajinomoto Co., Inc. PROCESS FOR PRODUCTION OF PROTEIN HAVING ALPHA-HYDROXYLANTIC PEPTIDYLGLYCIN MONOOXYGENASE ACTIVITY
US11680279B2 (en) 2017-11-29 2023-06-20 Ajinomoto Co., Inc. Method for producing objective substance
WO2019130723A1 (en) 2017-12-26 2019-07-04 Ajinomoto Co., Inc. Method of producing glycine by fermentation
EP3756466A4 (en) 2018-02-20 2021-11-24 Ajinomoto Co., Inc. RNA SILENCING INDUCTION PROCESS
JP7124338B2 (ja) 2018-02-27 2022-08-24 味の素株式会社 変異型グルタチオン合成酵素、及び、γ-グルタミルバリルグリシンの製造法
KR102744950B1 (ko) 2018-04-20 2024-12-20 아지노모토 가부시키가이샤 단백질의 분비 생산법
WO2020027251A1 (en) 2018-08-03 2020-02-06 Ajinomoto Co., Inc. Method for producing objective substance
US12241101B2 (en) 2018-08-10 2025-03-04 Kyowa Hakko Bio Co., Ltd. Microorganism producing polyunsaturated fatty acid and method for producing polyunsaturated fatty acid
WO2020032261A1 (ja) 2018-08-10 2020-02-13 協和発酵バイオ株式会社 エイコサペンタエン酸を生産する微生物及びエイコサペンタエン酸の製造法
CN112930359A (zh) 2018-10-25 2021-06-08 味之素株式会社 蛋白质的分泌生产方法
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WO2021125245A1 (ja) 2019-12-16 2021-06-24 協和発酵バイオ株式会社 改変されたラクトースパーミアーゼを有する微生物及びラクトース含有オリゴ糖の製造法
WO2021177392A1 (ja) 2020-03-04 2021-09-10 味の素株式会社 変異型トランスグルタミナーゼ
CN115667517A (zh) 2020-06-25 2023-01-31 协和发酵生化株式会社 二肽的制造方法
EP4223129A4 (en) 2020-09-29 2025-02-19 Ajinomoto Co., Inc. MUTANT TRANSGLUTAMINASE
WO2022092018A1 (ja) 2020-10-28 2022-05-05 味の素株式会社 L-アミノ酸の製造法
EP4289958A4 (en) 2021-02-08 2025-07-02 Kyowa Hakko Bio Co Ltd PROTEIN HAVING 1,3-FUCOSYLTRANSFERASE ACTIVITY, AND METHOD FOR PRODUCING FUCOSE-CONTAINING SUGAR
JPWO2022176994A1 (cg-RX-API-DMAC7.html) 2021-02-19 2022-08-25
EP4368722A4 (en) 2021-07-07 2025-11-26 Ajinomoto Kk METHOD FOR THE SECRETORIAL PROCESSING OF NON-NATURAL AMINO ACID-CONTAINING PROTEIN
JPWO2023120615A1 (cg-RX-API-DMAC7.html) 2021-12-21 2023-06-29
US20250215472A1 (en) 2022-03-25 2025-07-03 Kirin Holdings Kabushiki Kaisha Protein having alpha-1,2-fucosyltransferase activity and method for producing lacto-n-fucopentaose i (lnfpi)
EP4509613A1 (en) 2022-04-15 2025-02-19 Ajinomoto Co., Inc. Method for producing cultured meat
EP4516908A1 (en) 2022-04-28 2025-03-05 Kyowa Hakko Bio Co., Ltd. Protein having nampt activity, and method for producing nmn
US20250354186A1 (en) 2022-06-06 2025-11-20 Kyowa Hakko Bio Co., Ltd. Microorganism having improved 3'-sialyllactose productivity and production method of 3'-sialyllactose
JPWO2024005155A1 (cg-RX-API-DMAC7.html) 2022-06-30 2024-01-04
GB2621337A (en) 2022-08-08 2024-02-14 Mitsubishi Chemical Uk Ltd Process for the biological production of methacrylic acid and derivatives thereof
EP4632070A1 (en) 2022-12-09 2025-10-15 Kirin Holdings Kabushiki Kaisha Protein having polyethylene terephthalate decomposing activity and method for decomposing polyethylene terephthalate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3003925A (en) * 1956-05-17 1961-10-10 Kyowa Hakko Kogyo Kk Method of producing l-glutamic acid by fermentation
US3002889A (en) * 1960-06-20 1961-10-03 Kyowa Hakko Kogyo Kk Method of producing l-glutamic acid
US3220929A (en) * 1964-02-10 1965-11-30 Kyowa Hakko Kogyo Kk Microbiological production of amino acid by reductive amination
AU542264B2 (en) * 1979-06-01 1985-02-14 G.D. Searle & Co. Plasmid vectors
JPS57183799A (en) * 1981-04-17 1982-11-12 Kyowa Hakko Kogyo Co Ltd Novel plasmid

Also Published As

Publication number Publication date
EP0058889A1 (en) 1982-09-01
EP0058889B1 (en) 1986-12-03
CA1196588A (en) 1985-11-12
DE3274561D1 (en) 1987-01-15
JPH0112477B2 (cg-RX-API-DMAC7.html) 1989-03-01
JPS57134500A (en) 1982-08-19
US4617267A (en) 1986-10-14

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