DE2707565A1 - Syn-isomere von 3,7-disubstituierten-3-cephem-4-carbonsaeureverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel - Google Patents

Syn-isomere von 3,7-disubstituierten-3-cephem-4-carbonsaeureverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel

Info

Publication number
DE2707565A1
DE2707565A1 DE19772707565 DE2707565A DE2707565A1 DE 2707565 A1 DE2707565 A1 DE 2707565A1 DE 19772707565 DE19772707565 DE 19772707565 DE 2707565 A DE2707565 A DE 2707565A DE 2707565 A1 DE2707565 A1 DE 2707565A1
Authority
DE
Germany
Prior art keywords
group
formula
compounds according
amino
acetamido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19772707565
Other languages
German (de)
English (en)
Other versions
DE2707565C2 (US20080094685A1-20080424-C00004.png
Inventor
Hiromu Kochi
Takashi Masugi
Sakai Takao
Hisashi Takasugi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB14916/76A external-priority patent/GB1576625A/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of DE2707565A1 publication Critical patent/DE2707565A1/de
Application granted granted Critical
Publication of DE2707565C2 publication Critical patent/DE2707565C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19772707565 1976-04-12 1977-02-22 Syn-isomere von 3,7-disubstituierten-3-cephem-4-carbonsaeureverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel Granted DE2707565A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB14916/76A GB1576625A (en) 1976-04-12 1976-04-12 Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
GB2349076 1976-06-07
JP51125826A JPS5941995B2 (ja) 1976-04-12 1976-10-19 ３，７−ジ置換−３−セフエム−４−カルボン酸化合物およびその塩類およびそれらの製造方法

Publications (2)

Publication Number Publication Date
DE2707565A1 true DE2707565A1 (de) 1978-02-23
DE2707565C2 DE2707565C2 (US20080094685A1-20080424-C00004.png) 1988-06-30

Family

ID=27257189

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772707565 Granted DE2707565A1 (de) 1976-04-12 1977-02-22 Syn-isomere von 3,7-disubstituierten-3-cephem-4-carbonsaeureverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel

Country Status (13)

Country Link
AR (2) AR227864A1 (US20080094685A1-20080424-C00004.png)
AT (1) AT358728B (US20080094685A1-20080424-C00004.png)
CA (1) CA1337522C (US20080094685A1-20080424-C00004.png)
CH (2) CH638532A5 (US20080094685A1-20080424-C00004.png)
DE (1) DE2707565A1 (US20080094685A1-20080424-C00004.png)
DK (1) DK162391C (US20080094685A1-20080424-C00004.png)
ES (7) ES457191A1 (US20080094685A1-20080424-C00004.png)
FR (1) FR2348219A1 (US20080094685A1-20080424-C00004.png)
HU (1) HU177441B (US20080094685A1-20080424-C00004.png)
IE (1) IE45597B1 (US20080094685A1-20080424-C00004.png)
MX (1) MX4985E (US20080094685A1-20080424-C00004.png)
NL (1) NL191259C (US20080094685A1-20080424-C00004.png)
SE (2) SE443981B (US20080094685A1-20080424-C00004.png)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2806226A1 (de) * 1977-02-18 1978-08-24 Roussel Uclaf Oximderivate der 3-thiadiazolylthiomethyl-7-aminothiazolyl-acetamido- cephalosporansaeure, ihr herstellungsverfahren sowie pharmazeutische zusammensetzungen
DE2810922A1 (de) 1977-03-14 1978-09-21 Fujisawa Pharmaceutical Co Neue cephem- und cepham-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2812625A1 (de) * 1977-03-25 1978-09-28 Roussel Uclaf Oximderivate der 3-acetoxymethyl-7- aminothiazolyl-acetamido-cephalosporansaeure, ihre herstellung und pharmazeutische mittel
DE2716707A1 (de) * 1977-04-02 1978-10-19 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
DE2900961A1 (de) * 1978-01-13 1979-07-19 Takeda Chemical Industries Ltd Cephalosporine und verfahren zu deren herstellung
DE2912829A1 (de) * 1978-03-31 1979-10-04 Roussel Uclaf O-substituierte oximderivate der 7-aminotiaoyl-acetamido-cephalosporansaeure, ihre herstellung und pharmazeutische zusammensetzungen
EP0005830A1 (de) 1978-05-30 1979-12-12 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Cephalosporinderivate, deren Herstellung und die entsprechenden pharmazeutischen Präparate
DE2935232A1 (de) * 1978-09-04 1980-03-13 Fujisawa Pharmaceutical Co 3,7-disubstituierte-3-cephem-4- carbonsaeure-verbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
DE2936434A1 (de) * 1978-09-11 1980-03-20 Fujisawa Pharmaceutical Co Cephemverbindungen, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische mittel sowie ihre therapeutische verwendung fuer die behandlung von infektionserkrankungen bei menschen und tieren
EP0010667A1 (en) * 1978-10-17 1980-05-14 Fujisawa Pharmaceutical Co., Ltd. Cepham compounds, pharmaceutical compositions containing them and processes for the preparation thereof and of known cephem compounds
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
DE3003724A1 (de) * 1979-02-09 1980-08-21 Roussel Uclaf Neue oximderivate der 7-aminothiazolylacetamidocephalosporansaeure, ihre herstellung und verwendung
DE3027281A1 (de) * 1979-07-19 1981-02-12 Roussel Uclaf Alkyloximderivate der 7-(2-amino-4thiazolyl)-acetamido-cephalosporansaeure, ihre herstellung, neue zwischenprodukte sowie ihre anwendung als medikamente und in pharmazeutischen mitteln

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3192167A (en) * 1962-09-20 1965-06-29 Ogawa Abiko Low pressure liquid vaporizer which is electrically heated
FR2399418A1 (fr) * 1977-03-14 1979-03-02 Fujisawa Pharmaceutical Co Procede de preparation d'acides iminoacetiques et nouveaux produits ainsi obtenus, utilises pour la synthese d'acides cepham- ou cephem-carboxyliques
FR2553770B2 (fr) * 1978-03-31 1986-03-14 Roussel Uclaf Nouveaux produits derives de l'acide 2(2-amino thiazol-4-yl) 2-alcoxy-imino acetique substitues sur l'oxime et leur procede de preparation
FR2421907A1 (fr) * 1978-04-07 1979-11-02 Roussel Uclaf Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2438051A2 (fr) * 1978-10-05 1980-04-30 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-azidomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
FR2453161A1 (fr) * 1978-08-31 1980-10-31 Fujisawa Pharmaceutical Co Procede de preparation de derives d'acide thiazolylacetique et nouveaux produits ainsi obtenus
FR2462439A1 (fr) * 1979-07-26 1981-02-13 Roussel Uclaf Nouveau procede de preparation de produits derives de l'acide 7-/(2-aryl) 2-hydroxyimino acetamido/cephalosporanique
IL61458A0 (en) * 1979-12-07 1980-12-31 Erba Farmitalia N-substituted thiazolyl derivatives of oximino-substituted cephalosporins, their preparation and pharmalceutical compositions containing them
FR2506307A1 (fr) * 1981-05-22 1982-11-26 Roussel Uclaf Nouveaux derives substitues de l'acide 2-(2-amino 4-thiazolyl) 2-hydroxyimino acetique et leur procede de preparation
US4426528A (en) * 1982-04-01 1984-01-17 Eli Lilly And Company Purification of syn-(2-aminothiazol-4-yl)methoxyimino)acetic acid
FR2532936A1 (fr) * 1982-09-13 1984-03-16 Roussel Uclaf Nouveaux derives de l'acide 2-amino-thiazolyl-4-yl acetique comportant une fonction oxime substituee et leur procede de preparation
GB8324152D0 (en) * 1983-09-09 1983-10-12 Glaxo Group Ltd Chemical process
IT8448798A0 (it) * 1983-09-12 1984-09-05 Biochemie Gmbh Procedimento per la preparazione di antibiotici del tipo cefalosporina
GB2161476B (en) * 1984-05-25 1988-01-27 Toyama Chemical Co Ltd 2-aminothiazolyl-2-methoxyimino acetamides and their use in preparing cephalosporins
DE3750411T2 (de) * 1986-04-14 1995-03-16 Banyu Pharma Co Ltd Cephalosporinderivate, Verfahren zu ihrer Herstellung und antibakterielle Präparate.

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2223375A1 (de) * 1971-05-14 1972-11-23 Glaxo Lab Ltd Antibiotika und Verfahren zu ihrer Herstellung
DE2461478A1 (de) * 1973-12-25 1976-02-26 Takeda Chemical Industries Ltd Neue 7-(thiazolin-4-yl-acetamido)- cephalosporinderivate, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel
DE2604207A1 (de) * 1975-02-04 1976-08-05 Fujisawa Pharmaceutical Co 7-(alpha, alpha-disubstituierte- acetamido)-3-substituierte-3-cephem- 4-carbonsaeuren
DE2556736C2 (de) * 1974-12-19 1982-02-11 Takeda Chemical Industries, Ltd., Osaka Cephemverbindungen und sie enthaltende Arzneimittel
DE2702501C2 (de) * 1976-01-23 1982-11-18 Roussel-Uclaf, 75007 Paris Oximderivate von 7-Aminothiazolylacetamidocephalosporansäure (syn-Isomere), ihre Herstellung und pharmazeutische Zusammensetzungen
DE2713272C2 (de) * 1976-03-25 1983-01-20 Roussel-Uclaf, 75007 Paris Derivate der 7-Aminothiazolyl-acetamido-cephalosporansäure, ihre Herstellung und pharmazeutische Zusammensetzungen
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2346014A1 (fr) * 1976-01-23 1977-10-28 Roussel Uclaf Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2760484C2 (US20080094685A1-20080424-C00004.png) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2223375A1 (de) * 1971-05-14 1972-11-23 Glaxo Lab Ltd Antibiotika und Verfahren zu ihrer Herstellung
DE2461478A1 (de) * 1973-12-25 1976-02-26 Takeda Chemical Industries Ltd Neue 7-(thiazolin-4-yl-acetamido)- cephalosporinderivate, verfahren zur herstellung derselben und diese enthaltende pharmazeutische mittel
DE2556736C2 (de) * 1974-12-19 1982-02-11 Takeda Chemical Industries, Ltd., Osaka Cephemverbindungen und sie enthaltende Arzneimittel
DE2560398C2 (de) * 1974-12-19 1983-09-29 Takeda Chemical Industries, Ltd., Osaka 2-Amino-thiazol-4-yl-essigsäure-Derivate und Verfahren zu deren Herstellung
DE2604207A1 (de) * 1975-02-04 1976-08-05 Fujisawa Pharmaceutical Co 7-(alpha, alpha-disubstituierte- acetamido)-3-substituierte-3-cephem- 4-carbonsaeuren
DE2702501C2 (de) * 1976-01-23 1982-11-18 Roussel-Uclaf, 75007 Paris Oximderivate von 7-Aminothiazolylacetamidocephalosporansäure (syn-Isomere), ihre Herstellung und pharmazeutische Zusammensetzungen
DE2759895C2 (de) * 1976-01-23 1986-01-16 Roussel-Uclaf, Paris Verwendung von syn-Alkoxyiminoderivaten von Aminothiazolylessigsäuren zur Herstellung entsprechender 7-Aminothiazolyl-syn-alkoxyiminoacetamidocephalosporansäuren
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
DE2713272C2 (de) * 1976-03-25 1983-01-20 Roussel-Uclaf, 75007 Paris Derivate der 7-Aminothiazolyl-acetamido-cephalosporansäure, ihre Herstellung und pharmazeutische Zusammensetzungen
DE2760156C2 (US20080094685A1-20080424-C00004.png) * 1976-03-25 1987-08-27 Roussel-Uclaf, Paris, Fr

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
J. Heterocyclic Chem. 15, 1978, 1295-1298
J. Med. Chem. 22, 1979, 1214-1218
Liebigs Ann. Chem. 722, 1969, 222-224
Protective Groups in Organic Synthesis, T.W., GREENE, Harvard University, Wiley 1981, P. 208, 209
Tetrahedron Lett. 26, 1973, 2389-2392

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2806226A1 (de) * 1977-02-18 1978-08-24 Roussel Uclaf Oximderivate der 3-thiadiazolylthiomethyl-7-aminothiazolyl-acetamido- cephalosporansaeure, ihr herstellungsverfahren sowie pharmazeutische zusammensetzungen
DE2810922A1 (de) 1977-03-14 1978-09-21 Fujisawa Pharmaceutical Co Neue cephem- und cepham-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2858771C2 (US20080094685A1-20080424-C00004.png) * 1977-03-25 1990-09-06 Roussel-Uclaf S.A., Paris, Fr
DE2812625A1 (de) * 1977-03-25 1978-09-28 Roussel Uclaf Oximderivate der 3-acetoxymethyl-7- aminothiazolyl-acetamido-cephalosporansaeure, ihre herstellung und pharmazeutische mittel
DE2716707A1 (de) * 1977-04-02 1978-10-19 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
DE2900961A1 (de) * 1978-01-13 1979-07-19 Takeda Chemical Industries Ltd Cephalosporine und verfahren zu deren herstellung
DE2912829A1 (de) * 1978-03-31 1979-10-04 Roussel Uclaf O-substituierte oximderivate der 7-aminotiaoyl-acetamido-cephalosporansaeure, ihre herstellung und pharmazeutische zusammensetzungen
EP0005830A1 (de) 1978-05-30 1979-12-12 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Cephalosporinderivate, deren Herstellung und die entsprechenden pharmazeutischen Präparate
EP0045525A2 (de) * 1978-05-30 1982-02-10 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Cephalosporinderivate und deren Herstellung
EP0045525B1 (de) * 1978-05-30 1984-04-25 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Cephalosporinderivate und deren Herstellung
DE2935232A1 (de) * 1978-09-04 1980-03-13 Fujisawa Pharmaceutical Co 3,7-disubstituierte-3-cephem-4- carbonsaeure-verbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
DE2936434A1 (de) * 1978-09-11 1980-03-20 Fujisawa Pharmaceutical Co Cephemverbindungen, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische mittel sowie ihre therapeutische verwendung fuer die behandlung von infektionserkrankungen bei menschen und tieren
EP0010667A1 (en) * 1978-10-17 1980-05-14 Fujisawa Pharmaceutical Co., Ltd. Cepham compounds, pharmaceutical compositions containing them and processes for the preparation thereof and of known cephem compounds
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
DE3003724A1 (de) * 1979-02-09 1980-08-21 Roussel Uclaf Neue oximderivate der 7-aminothiazolylacetamidocephalosporansaeure, ihre herstellung und verwendung
DE3027281A1 (de) * 1979-07-19 1981-02-12 Roussel Uclaf Alkyloximderivate der 7-(2-amino-4thiazolyl)-acetamido-cephalosporansaeure, ihre herstellung, neue zwischenprodukte sowie ihre anwendung als medikamente und in pharmazeutischen mitteln

Also Published As

Publication number Publication date
FR2348219B1 (US20080094685A1-20080424-C00004.png) 1982-12-03
IE45597B1 (en) 1982-10-06
ES485061A1 (es) 1980-06-16
SE457351B (sv) 1988-12-19
CH638532A5 (de) 1983-09-30
FR2348219A1 (fr) 1977-11-10
HU177441B (en) 1981-10-28
IE45597L (en) 1977-10-12
ES485062A1 (es) 1980-06-16
MX4985E (es) 1983-01-31
AR227864A1 (es) 1982-12-30
ATA138477A (de) 1980-02-15
NL7703969A (nl) 1977-10-14
ES457191A1 (es) 1978-08-16
AT358728B (de) 1980-09-25
DE2707565C2 (US20080094685A1-20080424-C00004.png) 1988-06-30
CH643557A5 (en) 1984-06-15
SE443981B (sv) 1986-03-17
SE7701964L (sv) 1977-10-13
ES485064A1 (es) 1980-10-01
DK75077A (da) 1977-10-13
CA1337522C (en) 1995-11-07
ES477741A1 (es) 1980-04-01
ES485063A1 (es) 1980-06-16
NL191259C (nl) 1995-04-18
ES468719A1 (es) 1979-10-16
DK162391B (da) 1991-10-21
AR223143A1 (es) 1981-07-31
DK162391C (da) 1992-03-09
NL191259B (nl) 1994-11-16
SE8304465D0 (sv) 1983-08-17

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