US4131648A
(en)
*
|
1975-01-28 |
1978-12-26 |
Alza Corporation |
Structured orthoester and orthocarbonate drug delivery devices
|
US4150108A
(en)
*
|
1975-12-29 |
1979-04-17 |
Graham Neil B |
Injectable medicinal compositions
|
US4070347A
(en)
*
|
1976-08-16 |
1978-01-24 |
Alza Corporation |
Poly(orthoester) co- and homopolymers and poly(orthocarbonate) co- and homopolymers having carbonyloxy functionality
|
US4115544A
(en)
|
1976-08-18 |
1978-09-19 |
Alza Corporation |
Ocular system made of bioerodible esters having linear ether
|
US4259102A
(en)
*
|
1979-02-02 |
1981-03-31 |
Alza Corporation |
Composition comprising useful agent such as fertilizers, housed in heterocyclic polymer
|
US4282201A
(en)
*
|
1979-02-02 |
1981-08-04 |
Alza Corporation |
Pharmaceutical comprising drug and polymer
|
US4246397A
(en)
*
|
1979-02-02 |
1981-01-20 |
Alza Corporation |
Polymers comprising heterocyclic system
|
US4304767A
(en)
*
|
1980-05-15 |
1981-12-08 |
Sri International |
Polymers of di- (and higher functionality) ketene acetals and polyols
|
US4346709A
(en)
*
|
1980-11-10 |
1982-08-31 |
Alza Corporation |
Drug delivery devices comprising erodible polymer and erosion rate modifier
|
US4675189A
(en)
*
|
1980-11-18 |
1987-06-23 |
Syntex (U.S.A.) Inc. |
Microencapsulation of water soluble active polypeptides
|
US4764380A
(en)
*
|
1982-03-22 |
1988-08-16 |
Alza Corporation |
Drug delivery system comprising a volume increasing matrix containing a plurality of tiny pills
|
US4484923A
(en)
*
|
1982-03-25 |
1984-11-27 |
Alza Corporation |
Method for administering immunopotentiator
|
US5248700A
(en)
*
|
1982-05-14 |
1993-09-28 |
Akzo Nv |
Active agent containing solid structures for prolonged release of active agents
|
JPS5931701A
(ja)
*
|
1982-08-16 |
1984-02-20 |
Nitto Electric Ind Co Ltd |
液状活性物質含有膜及びその製造方法
|
US4489056A
(en)
*
|
1982-06-30 |
1984-12-18 |
Merck & Co., Inc. |
Acid anhydrides as rate controlling agent for the erosion of polymers which latter polymers have beneficial substances dispersed throughout their matrix or where the polymer matrix surrounds the beneficial substance
|
CH660488A5
(en)
*
|
1982-12-17 |
1987-04-30 |
Sandoz Ag |
(Co)oligomeric hydroxycarboxylic acid derivatives, the preparation thereof, and the use thereof in pharmaceutical compositions
|
JPS59155451A
(ja)
*
|
1983-02-22 |
1984-09-04 |
Asahi Glass Co Ltd |
香料含有樹脂
|
US4673405A
(en)
*
|
1983-03-04 |
1987-06-16 |
Alza Corporation |
Osmotic system with instant drug availability
|
US4576604A
(en)
*
|
1983-03-04 |
1986-03-18 |
Alza Corporation |
Osmotic system with instant drug availability
|
JPS6075476A
(ja)
*
|
1983-10-03 |
1985-04-27 |
Toagosei Chem Ind Co Ltd |
環状化合物
|
US5855908A
(en)
*
|
1984-05-01 |
1999-01-05 |
University Of Utah Research Foundation |
Non-dissolvable drug-containing dosage-forms for use in the transmucosal delivery of a drug to a patient
|
US4863737A
(en)
*
|
1985-05-01 |
1989-09-05 |
University Of Utah |
Compositions and methods of manufacture of compressed powder medicaments
|
US5456663A
(en)
*
|
1984-05-25 |
1995-10-10 |
Lemelson; Jerome H. |
Drugs and methods for treating diseases
|
US4639366A
(en)
*
|
1984-06-06 |
1987-01-27 |
Merck & Co., Inc. |
Polymers containing pendant acid functionalities and labile backbone bonds
|
US4880635B1
(en)
*
|
1984-08-08 |
1996-07-02 |
Liposome Company |
Dehydrated liposomes
|
US5288497A
(en)
*
|
1985-05-01 |
1994-02-22 |
The University Of Utah |
Compositions of oral dissolvable medicaments
|
US5132114A
(en)
*
|
1985-05-01 |
1992-07-21 |
University Of Utah Research Foundation |
Compositions and methods of manufacture of compressed powder medicaments
|
US5122127A
(en)
*
|
1985-05-01 |
1992-06-16 |
University Of Utah |
Apparatus and methods for use in administering medicaments by direct medicament contact to mucosal tissues
|
US4885173A
(en)
*
|
1985-05-01 |
1989-12-05 |
University Of Utah |
Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular activities
|
US4671953A
(en)
*
|
1985-05-01 |
1987-06-09 |
University Of Utah Research Foundation |
Methods and compositions for noninvasive administration of sedatives, analgesics, and anesthetics
|
US4780319A
(en)
*
|
1985-07-08 |
1988-10-25 |
Merck & Co., Inc. |
Organic acids as catalysts for the erosion of polymers
|
US4855132A
(en)
*
|
1986-02-25 |
1989-08-08 |
S R I International |
Method of preparing bioerodible polymers having pH sensitivity in the acid range and resulting product
|
US4764364A
(en)
*
|
1986-02-25 |
1988-08-16 |
S R I International |
Method of preparing bioerodible polymers having pH sensitivity in the acid range and resulting product
|
EP0245840B1
(de)
*
|
1986-05-15 |
1993-12-01 |
Hoechst Aktiengesellschaft |
Biologisch abbaubare Polymere für Depotzubereitungen mit kontrollierter Wirkstoffabgabe
|
JPH0798713B2
(ja)
*
|
1986-05-16 |
1995-10-25 |
住友化学工業株式会社 |
粒状肥料組成物およびその製造法
|
USRE33976E
(en)
*
|
1986-05-16 |
1992-06-30 |
Sumitomo Chemical Co., Ltd. |
Granular fertilizer compositions
|
US4841968A
(en)
*
|
1986-09-26 |
1989-06-27 |
Southern Research Institute |
Antithrombotic/thrombolytic suture and methods of making and using the same
|
DE3700128A1
(de)
*
|
1987-01-03 |
1988-07-14 |
Hoechst Ag |
Biologisch abbaubare poly- (hydroxyalkyl)- aminodicarbonsaeure-derivate, verfahren zu ihrer herstellung und verwendung derselben fuer depotzubereitungen mit kontrollierter wirkstoffabgabe
|
US4913903A
(en)
*
|
1987-02-04 |
1990-04-03 |
Alza Corporation |
Post-surgical applications for bioerodible polymers
|
US4851232A
(en)
*
|
1987-02-13 |
1989-07-25 |
Alza Corporation |
Drug delivery system with means for obtaining desirable in vivo release rate pattern
|
US5985354A
(en)
|
1995-06-07 |
1999-11-16 |
Brown University Research Foundation |
Preparation of multiwall polymeric microcapsules from hydrophilic polymers
|
US4897268A
(en)
*
|
1987-08-03 |
1990-01-30 |
Southern Research Institute |
Drug delivery system and method of making the same
|
US4950795A
(en)
*
|
1987-08-27 |
1990-08-21 |
Ciba-Geigy Corporation |
Oligomeric benzil ketals and their use as photoinitiators
|
JP2563814B2
(ja)
*
|
1987-11-12 |
1996-12-18 |
日東電工株式会社 |
液状活性物質徐放デバイス
|
US4957998A
(en)
*
|
1988-08-22 |
1990-09-18 |
Pharmaceutical Delivery Systems, Inc. |
Polymers containing acetal, carboxy-acetal, ortho ester and carboxyortho ester linkages
|
US4990336A
(en)
*
|
1989-02-08 |
1991-02-05 |
Biosearch, Inc. |
Sustained release dosage form
|
US5278142A
(en)
*
|
1989-03-20 |
1994-01-11 |
Orbon Corporation |
Systemic delivery of polypeptides through the eye
|
US5182258A
(en)
*
|
1989-03-20 |
1993-01-26 |
Orbon Corporation |
Systemic delivery of polypeptides through the eye
|
US5108755A
(en)
*
|
1989-04-27 |
1992-04-28 |
Sri International |
Biodegradable composites for internal medical use
|
US5013821A
(en)
*
|
1989-06-15 |
1991-05-07 |
Pharmaceutical Delivery Systems, Inc. |
Ortho and thio-ortho ester polymer
|
US5660851A
(en)
*
|
1989-12-26 |
1997-08-26 |
Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem |
Ocular inserts
|
DE4002736A1
(de)
*
|
1990-01-31 |
1991-08-01 |
Hoechst Ag |
Biologisch abbaubare polymere, verfahren zu ihrer herstellung und verwendung derselben fuer depotzubereitungen mit kontrollierter wirkstoffabgabe
|
US5126147A
(en)
*
|
1990-02-08 |
1992-06-30 |
Biosearch, Inc. |
Sustained release dosage form
|
NZ239370A
(en)
*
|
1990-08-22 |
1994-04-27 |
Merck & Co Inc |
Bioerodible implantable controlled release dosage form comprising a poly(ortho ester) or a polyacetal with an active agent incorporated into the chain backbone
|
US5156850A
(en)
*
|
1990-08-31 |
1992-10-20 |
Alza Corporation |
Dosage form for time-varying patterns of drug delivery
|
US5232705A
(en)
*
|
1990-08-31 |
1993-08-03 |
Alza Corporation |
Dosage form for time-varying patterns of drug delivery
|
US5620700A
(en)
*
|
1990-10-30 |
1997-04-15 |
Alza Corporation |
Injectable drug delivery system and method
|
IE920040A1
(en)
*
|
1991-01-09 |
1992-07-15 |
Alza Corp |
Bioerodible devices and compositions for diffusional release¹of agents
|
US5993805A
(en)
*
|
1991-04-10 |
1999-11-30 |
Quadrant Healthcare (Uk) Limited |
Spray-dried microparticles and their use as therapeutic vehicles
|
GB9107628D0
(en)
|
1991-04-10 |
1991-05-29 |
Moonbrook Limited |
Preparation of diagnostic agents
|
EP0514790A2
(de)
*
|
1991-05-24 |
1992-11-25 |
Hoechst Aktiengesellschaft |
Polykondensate, die Weinsäurederivate enthalten, Verfahren zu ihrer Herstellung und Verwendung derselben
|
AU2261592A
(en)
*
|
1991-06-20 |
1993-01-25 |
Pharmaceutical Delivery Systems, Inc. |
Pulsed release of high molecular weight therapeutic agents from bioerodible polymer compositions
|
US5190765A
(en)
*
|
1991-06-27 |
1993-03-02 |
Alza Corporation |
Therapy delayed
|
US5160744A
(en)
*
|
1991-06-27 |
1992-11-03 |
Alza Corporation |
Verapmil therapy
|
US6764697B1
(en)
|
1991-06-27 |
2004-07-20 |
Alza Corporation |
System for delaying drug delivery up to seven hours
|
US5252338A
(en)
*
|
1991-06-27 |
1993-10-12 |
Alza Corporation |
Therapy delayed
|
JPH05202177A
(ja)
*
|
1991-09-06 |
1993-08-10 |
Teijin Ltd |
生分解性共重合体、及びそれを含有する医薬品組成物
|
US6515009B1
(en)
|
1991-09-27 |
2003-02-04 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
US5811447A
(en)
|
1993-01-28 |
1998-09-22 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
US5254345A
(en)
*
|
1991-10-11 |
1993-10-19 |
Merck & Co., Inc. |
Poly(orthocarbonate acetal) bioerodible polymers
|
WO1993015767A1
(en)
*
|
1992-02-05 |
1993-08-19 |
Merck & Co., Inc. |
Implant therapy for bone growth stimulation
|
US5540912A
(en)
*
|
1992-03-30 |
1996-07-30 |
Alza Corporation |
Viscous suspensions of controlled-release drug particles
|
WO1993020138A2
(en)
*
|
1992-03-30 |
1993-10-14 |
Alza Corporation |
Polymer system containing a partially soluble compound
|
US5571525A
(en)
*
|
1992-03-30 |
1996-11-05 |
Alza Corporation |
Erosion rate modifier for use in bioerodible drug delivery devices and method of use
|
US5518730A
(en)
|
1992-06-03 |
1996-05-21 |
Fuisz Technologies Ltd. |
Biodegradable controlled release flash flow melt-spun delivery system
|
US5700485A
(en)
*
|
1992-09-10 |
1997-12-23 |
Children's Medical Center Corporation |
Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid
|
CA2144407C
(en)
*
|
1992-09-10 |
2000-05-30 |
Charles B. Berde |
Biodegradable polymer matrices for sustained delivery of local anesthetic agents
|
US5922340A
(en)
*
|
1992-09-10 |
1999-07-13 |
Children's Medical Center Corporation |
High load formulations and methods for providing prolonged local anesthesia
|
US5378468A
(en)
*
|
1992-09-22 |
1995-01-03 |
The Mennen Company |
Composition containing body activated fragrance for contacting the skin and method of use
|
US6306421B1
(en)
|
1992-09-25 |
2001-10-23 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
US6251920B1
(en)
|
1993-05-13 |
2001-06-26 |
Neorx Corporation |
Prevention and treatment of cardiovascular pathologies
|
US6395494B1
(en)
*
|
1993-05-13 |
2002-05-28 |
Neorx Corporation |
Method to determine TGF-β
|
EP1826280A3
(en)
|
1992-09-25 |
2007-12-05 |
Boston Scientific Limited |
Therapeutic conjugates inhibiting vascular smooth muscle cells
|
US5770609A
(en)
*
|
1993-01-28 |
1998-06-23 |
Neorx Corporation |
Prevention and treatment of cardiovascular pathologies
|
AU673885B2
(en)
*
|
1992-12-29 |
1996-11-28 |
Insite Vision Incorporated |
Bioerodible controlled delivery system
|
MY113268A
(en)
|
1992-12-29 |
2002-01-31 |
Insite Vision Incorporated |
Plasticized bioerodible controlled delivery system
|
US5981568A
(en)
*
|
1993-01-28 |
1999-11-09 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
US6663881B2
(en)
|
1993-01-28 |
2003-12-16 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
US5595722A
(en)
*
|
1993-01-28 |
1997-01-21 |
Neorx Corporation |
Method for identifying an agent which increases TGF-beta levels
|
JPH08506112A
(ja)
|
1993-01-28 |
1996-07-02 |
ネオルックス コーポレイション |
血管平滑筋細胞の治療用インヒビター
|
US6491938B2
(en)
|
1993-05-13 |
2002-12-10 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
WO1996040098A2
(en)
|
1995-06-07 |
1996-12-19 |
Neorx Corporation |
Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
|
US6440457B1
(en)
*
|
1993-05-27 |
2002-08-27 |
Alza Corporation |
Method of administering antidepressant dosage form
|
US5431630A
(en)
*
|
1993-09-07 |
1995-07-11 |
Surgic-Acid, Inc. |
Needle guard and nonreusable syringe
|
DE4407898A1
(de)
*
|
1994-03-09 |
1995-09-14 |
Hoechst Ag |
Nanopartikel, enthaltend einen Wirkstoff und ein Polyketalweinsäureamid, Verfahren zu ihrer Herstellung und Verwendung derselben
|
US5626862A
(en)
|
1994-08-02 |
1997-05-06 |
Massachusetts Institute Of Technology |
Controlled local delivery of chemotherapeutic agents for treating solid tumors
|
US6063116A
(en)
*
|
1994-10-26 |
2000-05-16 |
Medarex, Inc. |
Modulation of cell proliferation and wound healing
|
US6063396A
(en)
*
|
1994-10-26 |
2000-05-16 |
Houston Biotechnology Incorporated |
Methods and compositions for the modulation of cell proliferation and wound healing
|
US5631024A
(en)
*
|
1995-05-22 |
1997-05-20 |
Enviroquest, Ltd. |
Medicaments for beneficial insects and method
|
US5912268A
(en)
*
|
1995-05-22 |
1999-06-15 |
Alza Corporation |
Dosage form and method for treating incontinence
|
US6262115B1
(en)
*
|
1995-05-22 |
2001-07-17 |
Alza Coporation |
Method for the management of incontinence
|
US7611533B2
(en)
*
|
1995-06-07 |
2009-11-03 |
Cook Incorporated |
Coated implantable medical device
|
CA2195119C
(en)
*
|
1995-06-09 |
2001-09-11 |
Mark Chasin |
Formulations and methods for providing prolonged local anesthesia
|
US5736152A
(en)
*
|
1995-10-27 |
1998-04-07 |
Atrix Laboratories, Inc. |
Non-polymeric sustained release delivery system
|
US5968543A
(en)
*
|
1996-01-05 |
1999-10-19 |
Advanced Polymer Systems, Inc. |
Polymers with controlled physical state and bioerodibility
|
PT885014E
(pt)
|
1996-03-05 |
2003-02-28 |
Robert Gurny |
Composicoes farmaceuticas contendo polimeros orto ester tamponados
|
US6096339A
(en)
*
|
1997-04-04 |
2000-08-01 |
Alza Corporation |
Dosage form, process of making and using same
|
JPH11511763A
(ja)
|
1996-06-24 |
1999-10-12 |
ユーロ―セルティーク,エス.エイ. |
安全な局所麻酔の提供方法
|
US6046187A
(en)
|
1996-09-16 |
2000-04-04 |
Children's Medical Center Corporation |
Formulations and methods for providing prolonged local anesthesia
|
EP1690531A3
(en)
*
|
1996-09-30 |
2010-01-20 |
Alza Corporation |
Dosage form and method for administering drug
|
US6919373B1
(en)
*
|
1996-11-12 |
2005-07-19 |
Alza Corporation |
Methods and devices for providing prolonged drug therapy
|
US5788987A
(en)
|
1997-01-29 |
1998-08-04 |
Poli Industria Chimica Spa |
Methods for treating early morning pathologies
|
EP2292225B9
(en)
|
1997-03-31 |
2012-06-27 |
Boston Scientific Scimed Limited |
Dosage form comprising taxol in crystalline form
|
IL129951A0
(en)
|
1997-07-02 |
2000-02-29 |
Euro Celtique Sa |
Prolonged anesthesia in joints and body spaces
|
US20040062799A1
(en)
*
|
1997-09-29 |
2004-04-01 |
Ayer Atul D. |
Therapeutic composition and delivery system for administering drug
|
US6787157B1
(en)
*
|
1998-03-10 |
2004-09-07 |
Abbott Laboratories |
Multiphase active ingredient-containing formulations
|
KR20010071827A
(ko)
*
|
1998-07-10 |
2001-07-31 |
앤더슨 데릭 제이. |
반점성망막 퇴행에서 신혈관 신생의 예방치료
|
AU2610000A
(en)
|
1999-01-12 |
2000-08-01 |
Cambridge University Technical Services Limited |
Compounds and methods to inhibit or augment an inflammatory response
|
AUPQ496500A0
(en)
*
|
2000-01-06 |
2000-02-03 |
University Of Sydney, The |
Kit
|
CA2407154A1
(en)
|
2000-04-27 |
2001-11-01 |
Verion, Inc |
Zero order release and temperature-controlled microcapsules and process for the preparation thereof
|
US20050042194A1
(en)
|
2000-05-11 |
2005-02-24 |
A.P. Pharma, Inc. |
Semi-solid delivery vehicle and pharmaceutical compositions
|
US6613355B2
(en)
|
2000-05-11 |
2003-09-02 |
A.P. Pharma, Inc. |
Semi-solid delivery vehicle and pharmaceutical compositions
|
EP1289565B1
(en)
|
2000-06-02 |
2015-04-22 |
Bracco Suisse SA |
Compounds for targeting endothelial cells
|
ES2294026T3
(es)
*
|
2000-09-06 |
2008-04-01 |
Ap Pharma, Inc. |
Polimeros degradables de poliacetal.
|
AU2003267309A1
(en)
|
2000-11-16 |
2004-04-08 |
Microspherix Llc |
Flexible and/or elastic brachytherapy seed or strand
|
US20030152637A1
(en)
*
|
2001-01-25 |
2003-08-14 |
Mark Chasin |
Local anesthetic, and method of use
|
AU2002253454A1
(en)
*
|
2001-04-06 |
2002-10-21 |
Bracco Research S.A. |
Method for improved measurement of local physical parameters in afluid-filled cavity
|
US6613083B2
(en)
|
2001-05-02 |
2003-09-02 |
Eckhard Alt |
Stent device and method
|
US6590059B2
(en)
|
2001-05-11 |
2003-07-08 |
Ap Pharma, Inc. |
Bioerodible polyorthoesters from dioxolane-based diketene acetals
|
US20030152630A1
(en)
*
|
2001-05-11 |
2003-08-14 |
Ng Steven Y. |
PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers
|
US7232924B2
(en)
*
|
2001-06-11 |
2007-06-19 |
Xenoport, Inc. |
Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
|
AU2002345638A1
(en)
*
|
2001-06-11 |
2002-12-23 |
Xenoport, Inc. |
Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
|
ATE380029T1
(de)
*
|
2001-06-11 |
2007-12-15 |
Xenoport Inc |
Prodrugs von gaba-analoga, zusammensetzungen und ihre verwendungszwecke
|
US8048917B2
(en)
|
2005-04-06 |
2011-11-01 |
Xenoport, Inc. |
Prodrugs of GABA analogs, compositions and uses thereof
|
US6524606B1
(en)
|
2001-11-16 |
2003-02-25 |
Ap Pharma, Inc. |
Bioerodible polyorthoesters containing amine groups
|
WO2003051341A1
(en)
*
|
2001-12-18 |
2003-06-26 |
Alza Corporation |
Dosage form for providing time-varying patterns of drug delivery
|
US7261876B2
(en)
|
2002-03-01 |
2007-08-28 |
Bracco International Bv |
Multivalent constructs for therapeutic and diagnostic applications
|
AU2003278807A1
(en)
*
|
2002-03-01 |
2004-08-13 |
Bracco International B.V. |
Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy
|
US8623822B2
(en)
|
2002-03-01 |
2014-01-07 |
Bracco Suisse Sa |
KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
|
US7211240B2
(en)
*
|
2002-03-01 |
2007-05-01 |
Bracco International B.V. |
Multivalent constructs for therapeutic and diagnostic applications
|
EP2014310B8
(en)
|
2002-03-01 |
2012-12-26 |
Dyax Corp. |
KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
|
US7794693B2
(en)
*
|
2002-03-01 |
2010-09-14 |
Bracco International B.V. |
Targeting vector-phospholipid conjugates
|
US20040043070A1
(en)
*
|
2002-05-14 |
2004-03-04 |
Ayres James W. |
Hot melt coating by direct blending and coated substrates
|
US20040001889A1
(en)
|
2002-06-25 |
2004-01-01 |
Guohua Chen |
Short duration depot formulations
|
US20050232995A1
(en)
*
|
2002-07-29 |
2005-10-20 |
Yam Nyomi V |
Methods and dosage forms for controlled delivery of paliperidone and risperidone
|
US20050208132A1
(en)
*
|
2002-07-29 |
2005-09-22 |
Gayatri Sathyan |
Methods and dosage forms for reducing side effects of benzisozazole derivatives
|
MXPA05002632A
(es)
*
|
2002-09-09 |
2005-09-20 |
Nektar Therapeutics Al Corp |
Metodo para preparar derivados de polimeros solubles en agua que portan un acido carboxilico terminal.
|
US7354574B2
(en)
*
|
2002-11-07 |
2008-04-08 |
Advanced Ocular Systems Limited |
Treatment of ocular disease
|
US7045589B2
(en)
*
|
2002-11-15 |
2006-05-16 |
A.P. Pharma, Inc. |
Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them
|
AU2003293423A1
(en)
|
2002-12-06 |
2004-06-30 |
Xenoport, Inc. |
Carbidopa prodrugs and uses thereof
|
WO2004053192A1
(en)
*
|
2002-12-11 |
2004-06-24 |
Xenoport, Inc. |
Orally administered dosage forms of fused gaba analog prodrugs having reduced toxicity
|
JP5466350B2
(ja)
|
2003-03-03 |
2014-04-09 |
ダイアックス、コープ |
HGFレセプター(cMet)を特異的に結合するペプチドおよびその使用
|
WO2004089289A2
(en)
*
|
2003-03-31 |
2004-10-21 |
Xenoport, Inc. |
Treating or preventing hot flashes using prodrugs of gaba analogs
|
CA2523859C
(en)
*
|
2003-04-29 |
2011-08-02 |
The General Hospital Corporation |
Methods and devices for the sustained release of multiple drugs
|
US20070141071A1
(en)
*
|
2003-05-14 |
2007-06-21 |
Oregon State University |
Hot melt coating by direct blending and coated substrates
|
US7083802B2
(en)
*
|
2003-07-31 |
2006-08-01 |
Advanced Ocular Systems Limited |
Treatment of ocular disease
|
EP2354120A1
(en)
|
2003-08-20 |
2011-08-10 |
XenoPort, Inc. |
Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
|
WO2005019163A2
(en)
*
|
2003-08-20 |
2005-03-03 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
|
KR20060119971A
(ko)
*
|
2003-09-11 |
2006-11-24 |
제노포트 인코포레이티드 |
Gaba 유사체의 전구약물을 이용한 요실금의 치료및/또는 예방
|
MXPA06003043A
(es)
*
|
2003-09-17 |
2006-05-31 |
Xenoport Inc |
Tratamiento o prevencion del sindrome piernas inquietas utilizando prodrogas de analogos gaba.
|
US7585517B2
(en)
*
|
2003-09-18 |
2009-09-08 |
Macusight, Inc. |
Transscleral delivery
|
US7083803B2
(en)
*
|
2003-09-19 |
2006-08-01 |
Advanced Ocular Systems Limited |
Ocular solutions
|
US7087237B2
(en)
*
|
2003-09-19 |
2006-08-08 |
Advanced Ocular Systems Limited |
Ocular solutions
|
US20050181018A1
(en)
*
|
2003-09-19 |
2005-08-18 |
Peyman Gholam A. |
Ocular drug delivery
|
US7329413B1
(en)
*
|
2003-11-06 |
2008-02-12 |
Advanced Cardiovascular Systems, Inc. |
Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof
|
JP2007520496A
(ja)
*
|
2004-02-04 |
2007-07-26 |
レットメッド ピーティーワイ リミテッド |
徐放性ステロイド組成物
|
US20050192257A1
(en)
*
|
2004-02-26 |
2005-09-01 |
Peyman Gholam A. |
Predictors for patients at risk for glaucoma from steroid therapy
|
EP1718314A1
(en)
*
|
2004-02-26 |
2006-11-08 |
Advanced Ocular Systems Limited |
Heparin for the treatment of ocular pathologies
|
ES2435398T3
(es)
|
2004-04-08 |
2013-12-19 |
Eye Co Pty Ltd. |
Tratamiento de retinopatía exudativa con mineralocorticoides
|
US20050261243A1
(en)
*
|
2004-04-21 |
2005-11-24 |
Peyman Gholam A |
Antiprostaglandins for the treatment of ocular pathologies
|
RU2365580C2
(ru)
*
|
2004-06-04 |
2009-08-27 |
Ксенопорт, Инк. |
Пролекарства леводопа, композиции на их основе и их применения
|
WO2005121070A1
(en)
*
|
2004-06-04 |
2005-12-22 |
Xenoport, Inc. |
Levodopa prodrugs, and compositions and uses thereof
|
US20060128676A1
(en)
*
|
2004-07-13 |
2006-06-15 |
Pharmacofore, Inc. |
Compositions of nicotinic agonists and therapeutic agents and methods for treating or preventing diseases or pain
|
US8541028B2
(en)
|
2004-08-04 |
2013-09-24 |
Evonik Corporation |
Methods for manufacturing delivery devices and devices thereof
|
US7566738B2
(en)
*
|
2004-11-03 |
2009-07-28 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
|
WO2006050472A2
(en)
*
|
2004-11-03 |
2006-05-11 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous and -phosphinic acids
|
MX2007005306A
(es)
*
|
2004-11-04 |
2007-06-11 |
Xenoport Inc |
Formas de dosis oral de liberacion sostenida de la prodroga gabapentina.
|
US20060122152A1
(en)
*
|
2004-12-03 |
2006-06-08 |
Peyman Gholam A |
Heparin for the treatment of ocular pathologies
|
US8663639B2
(en)
*
|
2005-02-09 |
2014-03-04 |
Santen Pharmaceutical Co., Ltd. |
Formulations for treating ocular diseases and conditions
|
GB2438544A
(en)
*
|
2005-02-09 |
2007-11-28 |
Cooper Internat Corp |
Liquid formulations for treatment of diseases or conditions
|
US7208611B2
(en)
*
|
2005-02-23 |
2007-04-24 |
Xenoport, Inc. |
Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
|
CN101163676A
(zh)
|
2005-02-23 |
2008-04-16 |
普雷萨药品公司 |
用于治疗运动障碍及其它cns适应症的多巴胺转运蛋白抑制剂
|
KR20070122519A
(ko)
*
|
2005-03-31 |
2007-12-31 |
에이피 파마, 인코포레이티드 |
Peg-폴리아세탈 이블록 및 삼블록 공중합체 및 약학조성물
|
CN101426529A
(zh)
*
|
2005-03-31 |
2009-05-06 |
阿帕医药有限公司 |
Peg-聚(原酸酯)接枝共聚物和药物组合物
|
WO2006122223A2
(en)
*
|
2005-05-10 |
2006-11-16 |
Emory University |
Strategies for delivery of active agents using micelles and particles
|
US7351740B2
(en)
*
|
2005-06-20 |
2008-04-01 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use
|
US7616111B2
(en)
|
2005-06-20 |
2009-11-10 |
Carestream Health, Inc. |
System to monitor the ingestion of medicines
|
US7782189B2
(en)
*
|
2005-06-20 |
2010-08-24 |
Carestream Health, Inc. |
System to monitor the ingestion of medicines
|
US20070014760A1
(en)
|
2005-07-18 |
2007-01-18 |
Peyman Gholam A |
Enhanced recovery following ocular surgery
|
AU2006270041B2
(en)
|
2005-07-18 |
2011-08-18 |
Minu, Llc |
Enhanced ocular neuroprotection/neurostimulation
|
EP1928450A2
(en)
*
|
2005-08-26 |
2008-06-11 |
Xenoport, Inc. |
Treating premature ejaculation using gabapentin and pregabalin prodrugs
|
JP5153641B2
(ja)
*
|
2005-12-05 |
2013-02-27 |
ゼノポート,インコーポレーテッド |
レボドパプロドラッグメシラート、その組成物、およびその使用法
|
CN101511170B
(zh)
*
|
2005-12-22 |
2014-03-26 |
奥克伍德药业有限公司 |
可升华持续释放传递系统和其制造方法
|
KR20140093764A
(ko)
|
2006-02-09 |
2014-07-28 |
산텐 세이야꾸 가부시키가이샤 |
안정한 제제와 그 제조 및 사용 방법
|
DK2374472T3
(en)
|
2006-03-16 |
2018-08-13 |
Dyax Corp |
Compositions and Methods for the Treatment of Eye Disorders
|
WO2007112052A2
(en)
*
|
2006-03-23 |
2007-10-04 |
Macusight, Inc. |
Formulations and methods for vascular permeability-related diseases or conditions
|
US20070264338A1
(en)
*
|
2006-05-12 |
2007-11-15 |
Shah Devang T |
Base-stabilized polyorthoester formulations
|
US20070265329A1
(en)
*
|
2006-05-12 |
2007-11-15 |
Devang Shah T |
Methods for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV)
|
US20070264339A1
(en)
*
|
2006-05-12 |
2007-11-15 |
Ap Pharma, Inc. |
Base-stabilized polyorthoester formulations
|
MX2008014794A
(es)
|
2006-05-26 |
2009-04-08 |
Pharmacofore Inc |
Liberacion controlada de opioides fenolicos.
|
US7458953B2
(en)
*
|
2006-06-20 |
2008-12-02 |
Gholam A. Peyman |
Ocular drainage device
|
US7875697B2
(en)
|
2006-06-29 |
2011-01-25 |
Medtronic, Inc. |
Poly(orthoester) polymers, and methods of making and using same
|
SI2046382T1
(sl)
|
2006-07-10 |
2016-12-30 |
ESBATech an Alcon Biomedical Research Unit LLC |
Protitelesa scFv, ki prehajajo epitelijske in/ali endotelijske plasti
|
WO2008027557A2
(en)
*
|
2006-08-31 |
2008-03-06 |
Spherics, Inc. |
Topiramate compositions and methods of enhancing its bioavailability
|
WO2008033572A1
(en)
*
|
2006-09-15 |
2008-03-20 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
|
US20080114076A1
(en)
*
|
2006-11-09 |
2008-05-15 |
Alcon Manufacturing Ltd. |
Punctal plug comprising a water-insoluble polymeric matrix
|
JP5411703B2
(ja)
|
2006-11-09 |
2014-02-12 |
アルコン リサーチ, リミテッド |
薬物送達のための水不溶性ポリマーマトリクス
|
WO2008061226A2
(en)
*
|
2006-11-17 |
2008-05-22 |
Supernus Pharmaceuticals Inc. |
Sustained-release formulations of topiramate
|
WO2008073257A1
(en)
*
|
2006-12-08 |
2008-06-19 |
Xenoport, Inc. |
Use of prodrugs of gaba analogs for treating diseases
|
US7709527B2
(en)
*
|
2006-12-21 |
2010-05-04 |
Xenoport, Inc. |
Levodopa dimethyl-substituted diester prodrugs compositions, and methods of use
|
US7829592B2
(en)
*
|
2006-12-21 |
2010-11-09 |
Xenoport, Inc. |
Catechol protected levodopa diester prodrugs, compositions, and methods of use
|
US20080265343A1
(en)
*
|
2007-04-26 |
2008-10-30 |
International Business Machines Corporation |
Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof
|
EP2222281B1
(en)
|
2007-12-20 |
2018-12-05 |
Evonik Corporation |
Process for preparing microparticles having a low residual solvent volume
|
US8956642B2
(en)
*
|
2008-04-18 |
2015-02-17 |
Medtronic, Inc. |
Bupivacaine formulation in a polyorthoester carrier
|
US8940315B2
(en)
*
|
2008-04-18 |
2015-01-27 |
Medtronic, Inc. |
Benzodiazepine formulation in a polyorthoester carrier
|
EP2303393A4
(en)
*
|
2008-05-07 |
2011-10-19 |
Obj Ltd |
METHOD AND APPARATUS FOR ENHANCED TRANSDERMAL DIFFUSION
|
MX2011000629A
(es)
|
2008-07-17 |
2011-04-26 |
Merial Ltd |
Formulaciones analgesicas inyectables de larga duracion para animales.
|
EP2147684A1
(en)
|
2008-07-22 |
2010-01-27 |
Bracco Imaging S.p.A |
Diagnostic Agents Selective Against Metalloproteases
|
US8399513B2
(en)
*
|
2008-10-20 |
2013-03-19 |
Xenoport, Inc. |
Levodopa prodrug mesylate hydrate
|
US9290445B2
(en)
*
|
2008-10-20 |
2016-03-22 |
Xenoport, Inc. |
Methods of synthesizing a levodopa ester prodrug
|
WO2010068827A1
(en)
*
|
2008-12-11 |
2010-06-17 |
A.P. Pharma, Inc. |
Methods for enhancing stability of polyorthoesters and their formulations
|
ES2921527T3
(es)
|
2009-06-03 |
2022-08-29 |
Forsight Vision5 Inc |
Administración de fármaco en segmento anterior
|
US20110060040A1
(en)
*
|
2009-09-04 |
2011-03-10 |
Xenoport, Inc. |
Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
|
US8709489B2
(en)
*
|
2009-09-30 |
2014-04-29 |
Surmodics, Inc. |
Emulsions containing arylboronic acids and medical articles made therefrom
|
WO2011046515A1
(en)
|
2009-10-14 |
2011-04-21 |
Nanyang Technological University |
Antiproliferative agent
|
NZ601747A
(en)
|
2009-11-09 |
2014-08-29 |
Xenoport Inc |
Pharmaceutical compositions and oral dosage forms of a levodopa prodrug and methods of use
|
EP2343046A1
(en)
|
2010-01-08 |
2011-07-13 |
Nirvana's Tree House B.V. |
Functionalised triblock copolymers and compositions containing such polymers
|
EP2575950A4
(en)
|
2010-05-25 |
2014-07-09 |
Internat Scient Pty Ltd |
ADMINISTRATION OF ORAL CARE PRODUCTS
|
US9463330B2
(en)
|
2010-06-17 |
2016-10-11 |
International Scientific Pty Ltd |
Delivery of skin care products
|
WO2012050907A2
(en)
|
2010-09-28 |
2012-04-19 |
The Regents Of The University Of California |
Gaba agonists in the treatment of disorders associated with metabolic syndrome and gaba combinations in treatment or prophylaxis of type i diabetes
|
US8580294B2
(en)
|
2010-10-19 |
2013-11-12 |
International Partnership For Microbicides |
Platinum-catalyzed intravaginal rings
|
EP2677960A4
(en)
|
2011-02-23 |
2016-11-16 |
Boston Scient Scimed Inc |
SYSTEM AND METHOD FOR PELVIC IMPLANT AND THERAPEUTIC AGENT
|
WO2012116209A1
(en)
|
2011-02-23 |
2012-08-30 |
Ams Research Corporation |
Drug releasing pelvic treatment system and method
|
JP5989780B2
(ja)
|
2011-09-14 |
2016-09-07 |
フォーサイト・ビジョン5・インコーポレイテッドForsight Vision5,Inc. |
眼挿入装置および方法
|
PT2782584T
(pt)
|
2011-11-23 |
2021-09-02 |
Therapeuticsmd Inc |
Preparações e terapias de substituição para hormonoterapias naturais combinadas
|
US9301920B2
(en)
|
2012-06-18 |
2016-04-05 |
Therapeuticsmd, Inc. |
Natural combination hormone replacement formulations and therapies
|
US9115066B2
(en)
|
2011-12-14 |
2015-08-25 |
Indicator Systems International, Inc. |
Trisubstituted methyl alcohols and their polymerizable derivatives
|
US20130338122A1
(en)
|
2012-06-18 |
2013-12-19 |
Therapeuticsmd, Inc. |
Transdermal hormone replacement therapies
|
US20150196640A1
(en)
|
2012-06-18 |
2015-07-16 |
Therapeuticsmd, Inc. |
Progesterone formulations having a desirable pk profile
|
US10806740B2
(en)
|
2012-06-18 |
2020-10-20 |
Therapeuticsmd, Inc. |
Natural combination hormone replacement formulations and therapies
|
US10806697B2
(en)
|
2012-12-21 |
2020-10-20 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
DK2911623T3
(da)
|
2012-10-26 |
2019-10-28 |
Forsight Vision5 Inc |
Oftalmisk system til langvarig frigivelse af lægemiddel til øjet
|
US11266661B2
(en)
|
2012-12-21 |
2022-03-08 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
US10471072B2
(en)
|
2012-12-21 |
2019-11-12 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
US9180091B2
(en)
|
2012-12-21 |
2015-11-10 |
Therapeuticsmd, Inc. |
Soluble estradiol capsule for vaginal insertion
|
US10568891B2
(en)
|
2012-12-21 |
2020-02-25 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
US10537581B2
(en)
|
2012-12-21 |
2020-01-21 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
US11246875B2
(en)
|
2012-12-21 |
2022-02-15 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
US9849180B2
(en)
|
2014-09-15 |
2017-12-26 |
Hui Rong Shen |
Long-acting semi-solid lipid formulations
|
US10220093B2
(en)
|
2013-02-28 |
2019-03-05 |
Mira Pharma Corporation |
Long-acting semi-solid lipid formulations
|
JP6454322B2
(ja)
|
2013-03-15 |
2019-01-16 |
ヘロン セラピューティクス, インコーポレイテッド |
ポリオルトエステルおよび非プロトン性溶媒の組成物
|
US10137031B2
(en)
|
2013-11-14 |
2018-11-27 |
International Partnership For Microbicides, Inc. |
Combination therapy intravaginal rings
|
EP3134070B1
(en)
|
2014-04-21 |
2020-09-23 |
Heron Therapeutics, Inc. |
Compositions of a polyorthoester and an organic acid excipient
|
US9801945B2
(en)
|
2014-04-21 |
2017-10-31 |
Heron Therapeutics, Inc. |
Long-acting polymeric delivery systems
|
DK3134068T3
(da)
|
2014-04-21 |
2021-10-04 |
Heron Therapeutics Inc |
Langtidsvirkende polymerafgivelsessystemer
|
WO2018048460A1
(en)
|
2014-04-21 |
2018-03-15 |
Heron Therapeutics, Inc. |
A pharmaceutical composition comprising a delivery system, an amide-type local anesthetic, and meloxicam
|
CA2947767A1
(en)
|
2014-05-22 |
2015-11-26 |
Therapeuticsmd, Inc. |
Natural combination hormone replacement formulations and therapies
|
EP3154552B1
(en)
|
2014-06-11 |
2021-03-24 |
International Scientific Pty Ltd |
Device and method to treat or prevent joint degeneration
|
CA2936740C
(en)
|
2014-10-31 |
2017-10-10 |
Purdue Pharma |
Methods and compositions particularly for treatment of attention deficit disorder
|
US20160296532A1
(en)
|
2015-04-13 |
2016-10-13 |
Forsight Vision5, Inc. |
Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
|
US10328087B2
(en)
|
2015-07-23 |
2019-06-25 |
Therapeuticsmd, Inc. |
Formulations for solubilizing hormones
|
US10335406B2
(en)
|
2015-10-01 |
2019-07-02 |
Elysium Therapeutics, Inc. |
Opioid compositions resistant to overdose and abuse
|
WO2017059459A1
(en)
|
2015-10-01 |
2017-04-06 |
Elysium Therapeutics, Inc. |
Polysubunit opioid prodrugs resistant to overdose and abuse
|
US10519442B2
(en)
|
2016-02-11 |
2019-12-31 |
City Of Hope |
Twist signaling inhibitor compositions and methods of using the same
|
WO2017173044A1
(en)
|
2016-04-01 |
2017-10-05 |
Therapeuticsmd Inc. |
Steroid hormone compositions in medium chain oils
|
CA3020153A1
(en)
|
2016-04-01 |
2017-10-05 |
Therapeuticsmd, Inc. |
Steroid hormone pharmaceutical composition
|
WO2017222834A1
(en)
|
2016-06-10 |
2017-12-28 |
City Of Hope |
Compositions and methods for mitochondrial genome editing
|
US10646540B2
(en)
|
2016-11-18 |
2020-05-12 |
City Of Hope |
Peptide inhibitors of twist
|
WO2018170465A1
(en)
|
2017-03-17 |
2018-09-20 |
Elysium Therapeutics, Inc. |
Polysubunit opioid prodrugs resistant to overdose and abuse
|
DK3615545T3
(da)
|
2017-04-24 |
2021-11-22 |
Cocrystal Pharma Inc |
Pyrrolopyrimidinderivativer, der er nyttige som hæmmere af replikation af influenzavirus
|
CA3067558A1
(en)
|
2017-06-16 |
2018-12-20 |
Avery Therapeutics, Inc. |
Three dimensional tissue compositions and methods of use
|
US11426418B2
(en)
|
2017-12-06 |
2022-08-30 |
Mira Pharma Corporation |
Injectable long-acting semi-solid gel formulations
|
US10561606B2
(en)
|
2017-12-06 |
2020-02-18 |
Mira Pharma Corporation |
Injectable long-acting local anesthetic semi-solid gel formulations
|
US20210121462A1
(en)
|
2018-07-27 |
2021-04-29 |
Cocrystal Pharma, Inc. |
Pyrrolo[2,3-b]pyridin derivatives as inhibitors of influenza virus replication
|
US20220056024A1
(en)
|
2018-09-10 |
2022-02-24 |
Cocrystal Pharma, Inc. |
Pyridopyrazine and pyridotriazine inhibitors of influenza virus replication
|
JP2022505183A
(ja)
|
2018-10-17 |
2022-01-14 |
コクリスタル ファーマ,インコーポレイテッド |
インフルエンザウイルス複製の阻害剤の組み合わせ
|
US10722473B2
(en)
|
2018-11-19 |
2020-07-28 |
Purdue Pharma L.P. |
Methods and compositions particularly for treatment of attention deficit disorder
|
US20220048897A1
(en)
|
2018-11-26 |
2022-02-17 |
Cocrystal Pharma, Inc. |
Inhibitors of influenza virus replication
|
KR20220140711A
(ko)
|
2020-01-13 |
2022-10-18 |
듀렉트 코퍼레이션 |
불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법
|
US11633405B2
(en)
|
2020-02-07 |
2023-04-25 |
Therapeuticsmd, Inc. |
Steroid hormone pharmaceutical formulations
|
WO2021188620A1
(en)
|
2020-03-17 |
2021-09-23 |
Cocrystal Pharma Inc. |
Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication
|
US20230159453A1
(en)
|
2020-04-10 |
2023-05-25 |
Cocrystal Pharma, Inc. |
Inhibitors of norovirus and coronavirus replication
|
AU2022322889A1
(en)
|
2021-08-03 |
2024-02-22 |
Cocrystal Pharma, Inc. |
Inhibitors for coronaviruses
|