US4131648A
(en)
*
|
1975-01-28 |
1978-12-26 |
Alza Corporation |
Structured orthoester and orthocarbonate drug delivery devices
|
US4150108A
(en)
*
|
1975-12-29 |
1979-04-17 |
Graham Neil B |
Injectable medicinal compositions
|
US4070347A
(en)
*
|
1976-08-16 |
1978-01-24 |
Alza Corporation |
Poly(orthoester) co- and homopolymers and poly(orthocarbonate) co- and homopolymers having carbonyloxy functionality
|
US4115544A
(en)
|
1976-08-18 |
1978-09-19 |
Alza Corporation |
Ocular system made of bioerodible esters having linear ether
|
US4259102A
(en)
*
|
1979-02-02 |
1981-03-31 |
Alza Corporation |
Composition comprising useful agent such as fertilizers, housed in heterocyclic polymer
|
US4282201A
(en)
*
|
1979-02-02 |
1981-08-04 |
Alza Corporation |
Pharmaceutical comprising drug and polymer
|
US4246397A
(en)
*
|
1979-02-02 |
1981-01-20 |
Alza Corporation |
Polymers comprising heterocyclic system
|
US4304767A
(en)
*
|
1980-05-15 |
1981-12-08 |
Sri International |
Polymers of di- (and higher functionality) ketene acetals and polyols
|
US4346709A
(en)
*
|
1980-11-10 |
1982-08-31 |
Alza Corporation |
Drug delivery devices comprising erodible polymer and erosion rate modifier
|
US4675189A
(en)
*
|
1980-11-18 |
1987-06-23 |
Syntex (U.S.A.) Inc. |
Microencapsulation of water soluble active polypeptides
|
US4764380A
(en)
*
|
1982-03-22 |
1988-08-16 |
Alza Corporation |
Drug delivery system comprising a volume increasing matrix containing a plurality of tiny pills
|
US4484923A
(en)
*
|
1982-03-25 |
1984-11-27 |
Alza Corporation |
Method for administering immunopotentiator
|
US5248700A
(en)
*
|
1982-05-14 |
1993-09-28 |
Akzo Nv |
Active agent containing solid structures for prolonged release of active agents
|
JPS5931701A
(ja)
*
|
1982-08-16 |
1984-02-20 |
Nitto Electric Ind Co Ltd |
液状活性物質含有膜及びその製造方法
|
US4489056A
(en)
*
|
1982-06-30 |
1984-12-18 |
Merck & Co., Inc. |
Acid anhydrides as rate controlling agent for the erosion of polymers which latter polymers have beneficial substances dispersed throughout their matrix or where the polymer matrix surrounds the beneficial substance
|
CH660488A5
(en)
*
|
1982-12-17 |
1987-04-30 |
Sandoz Ag |
(Co)oligomeric hydroxycarboxylic acid derivatives, the preparation thereof, and the use thereof in pharmaceutical compositions
|
JPS59155451A
(ja)
*
|
1983-02-22 |
1984-09-04 |
Asahi Glass Co Ltd |
香料含有樹脂
|
US4673405A
(en)
*
|
1983-03-04 |
1987-06-16 |
Alza Corporation |
Osmotic system with instant drug availability
|
US4576604A
(en)
*
|
1983-03-04 |
1986-03-18 |
Alza Corporation |
Osmotic system with instant drug availability
|
JPS6075476A
(ja)
*
|
1983-10-03 |
1985-04-27 |
Toagosei Chem Ind Co Ltd |
環状化合物
|
US4863737A
(en)
*
|
1985-05-01 |
1989-09-05 |
University Of Utah |
Compositions and methods of manufacture of compressed powder medicaments
|
US5855908A
(en)
*
|
1984-05-01 |
1999-01-05 |
University Of Utah Research Foundation |
Non-dissolvable drug-containing dosage-forms for use in the transmucosal delivery of a drug to a patient
|
US5456663A
(en)
*
|
1984-05-25 |
1995-10-10 |
Lemelson; Jerome H. |
Drugs and methods for treating diseases
|
US4639366A
(en)
*
|
1984-06-06 |
1987-01-27 |
Merck & Co., Inc. |
Polymers containing pendant acid functionalities and labile backbone bonds
|
US4880635B1
(en)
*
|
1984-08-08 |
1996-07-02 |
Liposome Company |
Dehydrated liposomes
|
US5132114A
(en)
*
|
1985-05-01 |
1992-07-21 |
University Of Utah Research Foundation |
Compositions and methods of manufacture of compressed powder medicaments
|
US5288497A
(en)
*
|
1985-05-01 |
1994-02-22 |
The University Of Utah |
Compositions of oral dissolvable medicaments
|
US5122127A
(en)
*
|
1985-05-01 |
1992-06-16 |
University Of Utah |
Apparatus and methods for use in administering medicaments by direct medicament contact to mucosal tissues
|
US4885173A
(en)
*
|
1985-05-01 |
1989-12-05 |
University Of Utah |
Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular activities
|
US4671953A
(en)
*
|
1985-05-01 |
1987-06-09 |
University Of Utah Research Foundation |
Methods and compositions for noninvasive administration of sedatives, analgesics, and anesthetics
|
US4780319A
(en)
*
|
1985-07-08 |
1988-10-25 |
Merck & Co., Inc. |
Organic acids as catalysts for the erosion of polymers
|
US4855132A
(en)
*
|
1986-02-25 |
1989-08-08 |
S R I International |
Method of preparing bioerodible polymers having pH sensitivity in the acid range and resulting product
|
US4764364A
(en)
*
|
1986-02-25 |
1988-08-16 |
S R I International |
Method of preparing bioerodible polymers having pH sensitivity in the acid range and resulting product
|
DE3788301D1
(de)
*
|
1986-05-15 |
1994-01-13 |
Hoechst Ag |
Biologisch abbaubare Polymere für Depotzubereitungen mit kontrollierter Wirkstoffabgabe.
|
JPH0798713B2
(ja)
*
|
1986-05-16 |
1995-10-25 |
住友化学工業株式会社 |
粒状肥料組成物およびその製造法
|
USRE33976E
(en)
*
|
1986-05-16 |
1992-06-30 |
Sumitomo Chemical Co., Ltd. |
Granular fertilizer compositions
|
US4841968A
(en)
*
|
1986-09-26 |
1989-06-27 |
Southern Research Institute |
Antithrombotic/thrombolytic suture and methods of making and using the same
|
DE3700128A1
(de)
*
|
1987-01-03 |
1988-07-14 |
Hoechst Ag |
Biologisch abbaubare poly- (hydroxyalkyl)- aminodicarbonsaeure-derivate, verfahren zu ihrer herstellung und verwendung derselben fuer depotzubereitungen mit kontrollierter wirkstoffabgabe
|
US4913903A
(en)
*
|
1987-02-04 |
1990-04-03 |
Alza Corporation |
Post-surgical applications for bioerodible polymers
|
US4851232A
(en)
*
|
1987-02-13 |
1989-07-25 |
Alza Corporation |
Drug delivery system with means for obtaining desirable in vivo release rate pattern
|
US5985354A
(en)
|
1995-06-07 |
1999-11-16 |
Brown University Research Foundation |
Preparation of multiwall polymeric microcapsules from hydrophilic polymers
|
US4897268A
(en)
*
|
1987-08-03 |
1990-01-30 |
Southern Research Institute |
Drug delivery system and method of making the same
|
US4950795A
(en)
*
|
1987-08-27 |
1990-08-21 |
Ciba-Geigy Corporation |
Oligomeric benzil ketals and their use as photoinitiators
|
JP2563814B2
(ja)
*
|
1987-11-12 |
1996-12-18 |
日東電工株式会社 |
液状活性物質徐放デバイス
|
US4957998A
(en)
*
|
1988-08-22 |
1990-09-18 |
Pharmaceutical Delivery Systems, Inc. |
Polymers containing acetal, carboxy-acetal, ortho ester and carboxyortho ester linkages
|
US4990336A
(en)
*
|
1989-02-08 |
1991-02-05 |
Biosearch, Inc. |
Sustained release dosage form
|
US5182258A
(en)
*
|
1989-03-20 |
1993-01-26 |
Orbon Corporation |
Systemic delivery of polypeptides through the eye
|
US5278142A
(en)
*
|
1989-03-20 |
1994-01-11 |
Orbon Corporation |
Systemic delivery of polypeptides through the eye
|
US5108755A
(en)
*
|
1989-04-27 |
1992-04-28 |
Sri International |
Biodegradable composites for internal medical use
|
US5013821A
(en)
*
|
1989-06-15 |
1991-05-07 |
Pharmaceutical Delivery Systems, Inc. |
Ortho and thio-ortho ester polymer
|
US5660851A
(en)
*
|
1989-12-26 |
1997-08-26 |
Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem |
Ocular inserts
|
DE4002736A1
(de)
*
|
1990-01-31 |
1991-08-01 |
Hoechst Ag |
Biologisch abbaubare polymere, verfahren zu ihrer herstellung und verwendung derselben fuer depotzubereitungen mit kontrollierter wirkstoffabgabe
|
US5126147A
(en)
*
|
1990-02-08 |
1992-06-30 |
Biosearch, Inc. |
Sustained release dosage form
|
NZ239370A
(en)
*
|
1990-08-22 |
1994-04-27 |
Merck & Co Inc |
Bioerodible implantable controlled release dosage form comprising a poly(ortho ester) or a polyacetal with an active agent incorporated into the chain backbone
|
US5232705A
(en)
*
|
1990-08-31 |
1993-08-03 |
Alza Corporation |
Dosage form for time-varying patterns of drug delivery
|
US5156850A
(en)
*
|
1990-08-31 |
1992-10-20 |
Alza Corporation |
Dosage form for time-varying patterns of drug delivery
|
US5620700A
(en)
*
|
1990-10-30 |
1997-04-15 |
Alza Corporation |
Injectable drug delivery system and method
|
WO1992011843A1
(en)
*
|
1991-01-09 |
1992-07-23 |
Alza Corporation |
Bioerodible devices and compositions for diffusional release of agents
|
US5993805A
(en)
|
1991-04-10 |
1999-11-30 |
Quadrant Healthcare (Uk) Limited |
Spray-dried microparticles and their use as therapeutic vehicles
|
GB9107628D0
(en)
|
1991-04-10 |
1991-05-29 |
Moonbrook Limited |
Preparation of diagnostic agents
|
EP0514790A2
(de)
*
|
1991-05-24 |
1992-11-25 |
Hoechst Aktiengesellschaft |
Polykondensate, die Weinsäurederivate enthalten, Verfahren zu ihrer Herstellung und Verwendung derselben
|
AU2261592A
(en)
*
|
1991-06-20 |
1993-01-25 |
Pharmaceutical Delivery Systems, Inc. |
Pulsed release of high molecular weight therapeutic agents from bioerodible polymer compositions
|
US6764697B1
(en)
|
1991-06-27 |
2004-07-20 |
Alza Corporation |
System for delaying drug delivery up to seven hours
|
US5190765A
(en)
*
|
1991-06-27 |
1993-03-02 |
Alza Corporation |
Therapy delayed
|
US5252338A
(en)
*
|
1991-06-27 |
1993-10-12 |
Alza Corporation |
Therapy delayed
|
US5160744A
(en)
*
|
1991-06-27 |
1992-11-03 |
Alza Corporation |
Verapmil therapy
|
JPH05202177A
(ja)
*
|
1991-09-06 |
1993-08-10 |
Teijin Ltd |
生分解性共重合体、及びそれを含有する医薬品組成物
|
US5811447A
(en)
*
|
1993-01-28 |
1998-09-22 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
US6515009B1
(en)
|
1991-09-27 |
2003-02-04 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
US5254345A
(en)
*
|
1991-10-11 |
1993-10-19 |
Merck & Co., Inc. |
Poly(orthocarbonate acetal) bioerodible polymers
|
AU3607293A
(en)
*
|
1992-02-05 |
1993-09-03 |
Merck & Co., Inc. |
Implant therapy for bone growth stimulation
|
AU3941793A
(en)
*
|
1992-03-30 |
1993-11-08 |
Alza Corporation |
Additives for bioerodible polymers to regulate degradation
|
MX9301823A
(es)
*
|
1992-03-30 |
1994-01-31 |
Alza Corp |
Composicion para el suministro de liberacion controlado de un agente biologicamente activo.
|
WO1993020138A2
(en)
*
|
1992-03-30 |
1993-10-14 |
Alza Corporation |
Polymer system containing a partially soluble compound
|
US5518730A
(en)
|
1992-06-03 |
1996-05-21 |
Fuisz Technologies Ltd. |
Biodegradable controlled release flash flow melt-spun delivery system
|
US5700485A
(en)
*
|
1992-09-10 |
1997-12-23 |
Children's Medical Center Corporation |
Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid
|
ES2170074T3
(es)
*
|
1992-09-10 |
2002-08-01 |
Childrens Medical Center |
Matrices de polimero biodegradables para la liberacion prolongada de agentes anestesicos locales.
|
US5922340A
(en)
*
|
1992-09-10 |
1999-07-13 |
Children's Medical Center Corporation |
High load formulations and methods for providing prolonged local anesthesia
|
US5378468A
(en)
*
|
1992-09-22 |
1995-01-03 |
The Mennen Company |
Composition containing body activated fragrance for contacting the skin and method of use
|
US6306421B1
(en)
|
1992-09-25 |
2001-10-23 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
US6395494B1
(en)
|
1993-05-13 |
2002-05-28 |
Neorx Corporation |
Method to determine TGF-β
|
US6251920B1
(en)
|
1993-05-13 |
2001-06-26 |
Neorx Corporation |
Prevention and treatment of cardiovascular pathologies
|
US5770609A
(en)
*
|
1993-01-28 |
1998-06-23 |
Neorx Corporation |
Prevention and treatment of cardiovascular pathologies
|
EP1826280A3
(en)
|
1992-09-25 |
2007-12-05 |
Boston Scientific Limited |
Therapeutic conjugates inhibiting vascular smooth muscle cells
|
MY113268A
(en)
*
|
1992-12-29 |
2002-01-31 |
Insite Vision Incorporated |
Plasticized bioerodible controlled delivery system
|
DE69329039T2
(de)
*
|
1992-12-29 |
2000-11-16 |
Insite Vision, Inc. |
Bioerodierbares system zur kontrollierten freigabe
|
WO1994016706A1
(en)
|
1993-01-28 |
1994-08-04 |
Neorx Corporation |
Therapeutic inhibitors of vascular smooth muscle cells
|
US6663881B2
(en)
|
1993-01-28 |
2003-12-16 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
US6491938B2
(en)
|
1993-05-13 |
2002-12-10 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
US5595722A
(en)
*
|
1993-01-28 |
1997-01-21 |
Neorx Corporation |
Method for identifying an agent which increases TGF-beta levels
|
US5981568A
(en)
|
1993-01-28 |
1999-11-09 |
Neorx Corporation |
Therapeutic inhibitor of vascular smooth muscle cells
|
US6440457B1
(en)
*
|
1993-05-27 |
2002-08-27 |
Alza Corporation |
Method of administering antidepressant dosage form
|
US5431630A
(en)
*
|
1993-09-07 |
1995-07-11 |
Surgic-Acid, Inc. |
Needle guard and nonreusable syringe
|
DE4407898A1
(de)
*
|
1994-03-09 |
1995-09-14 |
Hoechst Ag |
Nanopartikel, enthaltend einen Wirkstoff und ein Polyketalweinsäureamid, Verfahren zu ihrer Herstellung und Verwendung derselben
|
US5626862A
(en)
|
1994-08-02 |
1997-05-06 |
Massachusetts Institute Of Technology |
Controlled local delivery of chemotherapeutic agents for treating solid tumors
|
US6063116A
(en)
*
|
1994-10-26 |
2000-05-16 |
Medarex, Inc. |
Modulation of cell proliferation and wound healing
|
US6063396A
(en)
*
|
1994-10-26 |
2000-05-16 |
Houston Biotechnology Incorporated |
Methods and compositions for the modulation of cell proliferation and wound healing
|
US5631024A
(en)
*
|
1995-05-22 |
1997-05-20 |
Enviroquest, Ltd. |
Medicaments for beneficial insects and method
|
US6262115B1
(en)
*
|
1995-05-22 |
2001-07-17 |
Alza Coporation |
Method for the management of incontinence
|
US5912268A
(en)
*
|
1995-05-22 |
1999-06-15 |
Alza Corporation |
Dosage form and method for treating incontinence
|
AU6277396A
(en)
*
|
1995-06-07 |
1996-12-30 |
Neorx Corporation |
Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
|
US7611533B2
(en)
*
|
1995-06-07 |
2009-11-03 |
Cook Incorporated |
Coated implantable medical device
|
DE69632569T2
(de)
*
|
1995-06-09 |
2005-08-18 |
Euroceltique S.A. |
Formulierungen und verfahren für eine verlängerte lokalanästhesie
|
US5736152A
(en)
*
|
1995-10-27 |
1998-04-07 |
Atrix Laboratories, Inc. |
Non-polymeric sustained release delivery system
|
US5968543A
(en)
*
|
1996-01-05 |
1999-10-19 |
Advanced Polymer Systems, Inc. |
Polymers with controlled physical state and bioerodibility
|
PT885014E
(pt)
|
1996-03-05 |
2003-02-28 |
Robert Gurny |
Composicoes farmaceuticas contendo polimeros orto ester tamponados
|
US6096339A
(en)
*
|
1997-04-04 |
2000-08-01 |
Alza Corporation |
Dosage form, process of making and using same
|
AU733867B2
(en)
|
1996-06-24 |
2001-05-31 |
Euro-Celtique S.A. |
Methods for providing safe local anesthesia
|
US6046187A
(en)
*
|
1996-09-16 |
2000-04-04 |
Children's Medical Center Corporation |
Formulations and methods for providing prolonged local anesthesia
|
EP1690531A3
(en)
*
|
1996-09-30 |
2010-01-20 |
Alza Corporation |
Dosage form and method for administering drug
|
US6919373B1
(en)
*
|
1996-11-12 |
2005-07-19 |
Alza Corporation |
Methods and devices for providing prolonged drug therapy
|
US5788987A
(en)
|
1997-01-29 |
1998-08-04 |
Poli Industria Chimica Spa |
Methods for treating early morning pathologies
|
JP2001521503A
(ja)
|
1997-03-31 |
2001-11-06 |
ネオルックス コーポレイション |
血管平滑筋細胞の治療的阻害物質
|
KR100367144B1
(ko)
|
1997-07-02 |
2003-01-14 |
유로-셀티크 소시에떼 아노뉨 |
관절과 체강(body space)내에서 연장된 마취
|
US20040062799A1
(en)
*
|
1997-09-29 |
2004-04-01 |
Ayer Atul D. |
Therapeutic composition and delivery system for administering drug
|
US6787157B1
(en)
*
|
1998-03-10 |
2004-09-07 |
Abbott Laboratories |
Multiphase active ingredient-containing formulations
|
NZ509797A
(en)
*
|
1998-07-10 |
2003-11-28 |
Univ Sydney |
Prophylactic treatments of neovascularisation in macular degeneration using a steroid
|
AU2610000A
(en)
|
1999-01-12 |
2000-08-01 |
Cambridge University Technical Services Limited |
Compounds and methods to inhibit or augment an inflammatory response
|
AUPQ496500A0
(en)
*
|
2000-01-06 |
2000-02-03 |
University Of Sydney, The |
Kit
|
DE60128910T2
(de)
|
2000-04-27 |
2008-02-28 |
Verion Inc. |
Nullte-ordnung-freisetzung und temperatur-kontrollierte mikrokapseln sowie herstellungsverfahren
|
US20050042194A1
(en)
|
2000-05-11 |
2005-02-24 |
A.P. Pharma, Inc. |
Semi-solid delivery vehicle and pharmaceutical compositions
|
US6613355B2
(en)
|
2000-05-11 |
2003-09-02 |
A.P. Pharma, Inc. |
Semi-solid delivery vehicle and pharmaceutical compositions
|
EP2286843A3
(en)
|
2000-06-02 |
2011-08-03 |
Bracco Suisse SA |
Compounds for targeting endothelial cells
|
DE60131177T2
(de)
*
|
2000-09-06 |
2008-08-07 |
AP Pharma, Inc., Redwood |
Abbaubare polyacetal-polymere
|
AU2003267309A1
(en)
|
2000-11-16 |
2004-04-08 |
Microspherix Llc |
Flexible and/or elastic brachytherapy seed or strand
|
WO2002058670A1
(en)
*
|
2001-01-25 |
2002-08-01 |
Euroceltique S.A. |
Local anesthetic, and method of use
|
EP1387637B1
(en)
*
|
2001-04-06 |
2007-10-31 |
Bracco Research S.A. |
Apparatus for measuring local physical parameters in a fluid filled cavity
|
US6613083B2
(en)
|
2001-05-02 |
2003-09-02 |
Eckhard Alt |
Stent device and method
|
US20030152630A1
(en)
*
|
2001-05-11 |
2003-08-14 |
Ng Steven Y. |
PEG-POE, PEG-POE-PEG, and POE-PEG-POE block copolymers
|
US6590059B2
(en)
|
2001-05-11 |
2003-07-08 |
Ap Pharma, Inc. |
Bioerodible polyorthoesters from dioxolane-based diketene acetals
|
AU2002345664C1
(en)
*
|
2001-06-11 |
2008-03-06 |
Xenoport, Inc. |
Prodrugs of gaba analogs, compositions and uses thereof
|
US7232924B2
(en)
*
|
2001-06-11 |
2007-06-19 |
Xenoport, Inc. |
Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
|
EP1412324A4
(en)
*
|
2001-06-11 |
2004-09-29 |
Xenoport Inc |
AMINO ACID CONJUGATES THAT RESULT IN GABA ANALOGA LASTING SYSTEMIC CONCENTRATIONS
|
US8048917B2
(en)
|
2005-04-06 |
2011-11-01 |
Xenoport, Inc. |
Prodrugs of GABA analogs, compositions and uses thereof
|
US6524606B1
(en)
|
2001-11-16 |
2003-02-25 |
Ap Pharma, Inc. |
Bioerodible polyorthoesters containing amine groups
|
WO2003051341A1
(en)
*
|
2001-12-18 |
2003-06-26 |
Alza Corporation |
Dosage form for providing time-varying patterns of drug delivery
|
EP1587944A4
(en)
*
|
2002-03-01 |
2007-03-21 |
Dyax Corp |
KDR AND VEGF / KDR BINDING PEPTIDES AND THEIR USE FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES
|
US7794693B2
(en)
|
2002-03-01 |
2010-09-14 |
Bracco International B.V. |
Targeting vector-phospholipid conjugates
|
ES2506142T3
(es)
|
2002-03-01 |
2014-10-13 |
Dyax Corp. |
Péptidos de unión a KDR y a VEGF/KDR y su uso en diagnóstico
|
US7261876B2
(en)
|
2002-03-01 |
2007-08-28 |
Bracco International Bv |
Multivalent constructs for therapeutic and diagnostic applications
|
US7211240B2
(en)
*
|
2002-03-01 |
2007-05-01 |
Bracco International B.V. |
Multivalent constructs for therapeutic and diagnostic applications
|
US8623822B2
(en)
*
|
2002-03-01 |
2014-01-07 |
Bracco Suisse Sa |
KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
|
US20040043070A1
(en)
*
|
2002-05-14 |
2004-03-04 |
Ayres James W. |
Hot melt coating by direct blending and coated substrates
|
US20040001889A1
(en)
|
2002-06-25 |
2004-01-01 |
Guohua Chen |
Short duration depot formulations
|
US20050232995A1
(en)
|
2002-07-29 |
2005-10-20 |
Yam Nyomi V |
Methods and dosage forms for controlled delivery of paliperidone and risperidone
|
US20050208132A1
(en)
*
|
2002-07-29 |
2005-09-22 |
Gayatri Sathyan |
Methods and dosage forms for reducing side effects of benzisozazole derivatives
|
US7569214B2
(en)
|
2002-09-09 |
2009-08-04 |
Nektar Therapeutics Al, Corporation |
Method for preparing water-soluble polymer derivatives bearing a terminal carboxylic acid
|
US7354574B2
(en)
*
|
2002-11-07 |
2008-04-08 |
Advanced Ocular Systems Limited |
Treatment of ocular disease
|
US7045589B2
(en)
*
|
2002-11-15 |
2006-05-16 |
A.P. Pharma, Inc. |
Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them
|
WO2004052841A1
(en)
|
2002-12-06 |
2004-06-24 |
Xenoport, Inc. |
Carbidopa prodrugs and uses thereof
|
US20040162351A1
(en)
*
|
2002-12-11 |
2004-08-19 |
Gallop Mark A. |
Orally administered dosage forms of fused GABA analog prodrugs having reduced toxicity
|
DK2284180T3
(da)
|
2003-03-03 |
2015-12-21 |
Dyax Corp |
Anvendelser af peptider, som specifikt binder sig til HGF-receptor (cMET)
|
WO2004089289A2
(en)
*
|
2003-03-31 |
2004-10-21 |
Xenoport, Inc. |
Treating or preventing hot flashes using prodrugs of gaba analogs
|
EP1620060B1
(en)
*
|
2003-04-29 |
2010-03-24 |
The General Hospital Corporation |
Methods and devices for the sustained release of multiple drugs
|
US20070141071A1
(en)
*
|
2003-05-14 |
2007-06-21 |
Oregon State University |
Hot melt coating by direct blending and coated substrates
|
US7083802B2
(en)
*
|
2003-07-31 |
2006-08-01 |
Advanced Ocular Systems Limited |
Treatment of ocular disease
|
EP2354120A1
(en)
|
2003-08-20 |
2011-08-10 |
XenoPort, Inc. |
Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
|
US7109239B2
(en)
*
|
2003-08-20 |
2006-09-19 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
|
CA2537837A1
(en)
*
|
2003-09-11 |
2005-03-24 |
Xenoport, Inc. |
Treating and/or preventing urinary incontinence using prodrugs of gaba analogs
|
WO2005027850A2
(en)
*
|
2003-09-17 |
2005-03-31 |
Xenoport, Inc. |
Treating or preventing restless legs syndrome using prodrugs of gaba analogs
|
CA2539324A1
(en)
*
|
2003-09-18 |
2005-03-31 |
Macusight, Inc. |
Transscleral delivery
|
US7087237B2
(en)
*
|
2003-09-19 |
2006-08-08 |
Advanced Ocular Systems Limited |
Ocular solutions
|
US7083803B2
(en)
*
|
2003-09-19 |
2006-08-01 |
Advanced Ocular Systems Limited |
Ocular solutions
|
US20050181018A1
(en)
*
|
2003-09-19 |
2005-08-18 |
Peyman Gholam A. |
Ocular drug delivery
|
US7329413B1
(en)
*
|
2003-11-06 |
2008-02-12 |
Advanced Cardiovascular Systems, Inc. |
Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof
|
EP1711186A4
(en)
*
|
2004-02-04 |
2009-03-18 |
Retmed Pty Ltd |
SLOWLY RELEASED STEROID COMPOSITION
|
WO2005082376A1
(en)
*
|
2004-02-26 |
2005-09-09 |
Advanced Ocular Systems Limited |
Tetracycline derivatives for the treatment of ocular pathologies
|
US20050192257A1
(en)
*
|
2004-02-26 |
2005-09-01 |
Peyman Gholam A. |
Predictors for patients at risk for glaucoma from steroid therapy
|
DK1755616T3
(da)
|
2004-04-08 |
2013-11-25 |
Eye Co Pty Ltd |
Behandling af ekssudativ retinopati med mineralkortikoider
|
WO2005102303A2
(en)
*
|
2004-04-21 |
2005-11-03 |
Advanced Ocular Systems Limited |
Antiprostaglandins for the treatment of ocular pathologies
|
JP4781352B2
(ja)
*
|
2004-06-04 |
2011-09-28 |
ゼノポート,インコーポレーテッド |
レボドパプロドラッグおよびその組成物ならびにその使用
|
US7323585B2
(en)
*
|
2004-06-04 |
2008-01-29 |
Xenoport, Inc. |
Levodopa prodrugs, and compositions and uses thereof
|
US20060128676A1
(en)
*
|
2004-07-13 |
2006-06-15 |
Pharmacofore, Inc. |
Compositions of nicotinic agonists and therapeutic agents and methods for treating or preventing diseases or pain
|
WO2006078320A2
(en)
|
2004-08-04 |
2006-07-27 |
Brookwood Pharmaceuticals, Inc. |
Methods for manufacturing delivery devices and devices thereof
|
US7494985B2
(en)
*
|
2004-11-03 |
2009-02-24 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
|
WO2006050471A2
(en)
*
|
2004-11-03 |
2006-05-11 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
|
WO2006050514A1
(en)
|
2004-11-04 |
2006-05-11 |
Xenoport, Inc. |
Gabapentin prodrug sustained release oral dosage forms
|
US20060122152A1
(en)
*
|
2004-12-03 |
2006-06-08 |
Peyman Gholam A |
Heparin for the treatment of ocular pathologies
|
US8637070B2
(en)
*
|
2005-02-09 |
2014-01-28 |
Santen Pharmaceutical Co., Ltd. |
Rapamycin formulations and methods of their use
|
US8663639B2
(en)
*
|
2005-02-09 |
2014-03-04 |
Santen Pharmaceutical Co., Ltd. |
Formulations for treating ocular diseases and conditions
|
US7208611B2
(en)
*
|
2005-02-23 |
2007-04-24 |
Xenoport, Inc. |
Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
|
US8258305B2
(en)
|
2005-02-23 |
2012-09-04 |
Prexa Pharmaceuticals, Inc. |
Dopamine transporter inhibitors for use in treatment of movement disorders and other CNS indications
|
EP1865988A2
(en)
*
|
2005-03-31 |
2007-12-19 |
AP Pharma, Inc. |
Peg-polyacetal diblock and triblock copolymers and pharmaceutical compositions
|
CN101426529A
(zh)
*
|
2005-03-31 |
2009-05-06 |
阿帕医药有限公司 |
Peg-聚(原酸酯)接枝共聚物和药物组合物
|
WO2006122223A2
(en)
*
|
2005-05-10 |
2006-11-16 |
Emory University |
Strategies for delivery of active agents using micelles and particles
|
US7782189B2
(en)
*
|
2005-06-20 |
2010-08-24 |
Carestream Health, Inc. |
System to monitor the ingestion of medicines
|
WO2007002013A2
(en)
|
2005-06-20 |
2007-01-04 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use
|
US7616111B2
(en)
|
2005-06-20 |
2009-11-10 |
Carestream Health, Inc. |
System to monitor the ingestion of medicines
|
PL1904056T3
(pl)
|
2005-07-18 |
2009-09-30 |
Minu Llc |
Zastosowanie makrolidu do przywracania czucia rogówkowego
|
US20070014760A1
(en)
*
|
2005-07-18 |
2007-01-18 |
Peyman Gholam A |
Enhanced recovery following ocular surgery
|
US20070049626A1
(en)
*
|
2005-08-26 |
2007-03-01 |
Tran Pierre V |
Treating premature ejaculation using gabapentin and pregabalin prodrugs
|
ES2391575T3
(es)
|
2005-12-05 |
2012-11-27 |
Xenoport, Inc. |
Mesilato de profármaco de Levodopa, sus composiciones y sus usos
|
EP1962586B1
(en)
*
|
2005-12-22 |
2017-07-12 |
Oakwood Laboratories L.L.C. |
Sublimable sustained release delivery system and method of making same
|
EP2001438A2
(en)
|
2006-02-09 |
2008-12-17 |
Macusight, Inc. |
Stable formulations, and methods of their preparation and use
|
PL2374472T3
(pl)
|
2006-03-16 |
2018-11-30 |
Dyax Corp. |
Kompozycje i sposoby leczenia zaburzeń okulistycznych
|
ES2563288T3
(es)
|
2006-03-23 |
2016-03-14 |
Santen Pharmaceutical Co., Ltd |
Rapamicina en dosis bajas para el tratamiento de enfermedades relacionadas con la permeabilidad vascular
|
US20070265329A1
(en)
*
|
2006-05-12 |
2007-11-15 |
Devang Shah T |
Methods for the prevention of acute and delayed chemotherapy-induced nausea and vomiting (CINV)
|
US20070264339A1
(en)
*
|
2006-05-12 |
2007-11-15 |
Ap Pharma, Inc. |
Base-stabilized polyorthoester formulations
|
US20070264338A1
(en)
*
|
2006-05-12 |
2007-11-15 |
Shah Devang T |
Base-stabilized polyorthoester formulations
|
EP2402037B8
(en)
|
2006-05-26 |
2019-12-04 |
Signature Therapeutics, Inc. |
Controlled release of phenolic opioids
|
US7458953B2
(en)
*
|
2006-06-20 |
2008-12-02 |
Gholam A. Peyman |
Ocular drainage device
|
EP2044142A2
(en)
|
2006-06-29 |
2009-04-08 |
Medtronic, Inc. |
Poly(orthoester) polymers, and methods of making and using same
|
HUE032654T2
(en)
*
|
2006-07-10 |
2017-10-30 |
Esbatech Alcon Biomed Res Unit |
scFv antibodies that cross the epithelial and / or endothelial layers
|
US9744137B2
(en)
*
|
2006-08-31 |
2017-08-29 |
Supernus Pharmaceuticals, Inc. |
Topiramate compositions and methods of enhancing its bioavailability
|
US7585996B2
(en)
*
|
2006-09-15 |
2009-09-08 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
|
PL2091514T3
(pl)
|
2006-11-09 |
2014-03-31 |
Alcon Res Ltd |
Nierozpuszczalna w wodzie matryca polimerowa do dostarczania leku
|
US20080114076A1
(en)
*
|
2006-11-09 |
2008-05-15 |
Alcon Manufacturing Ltd. |
Punctal plug comprising a water-insoluble polymeric matrix
|
ES2312308T3
(es)
|
2006-11-17 |
2013-03-26 |
Supernus Pharmaceuticals, Inc. |
Formulaciones de liberación sostenida de topiramato
|
CN101652133A
(zh)
*
|
2006-12-08 |
2010-02-17 |
克塞诺波特公司 |
Gaba类似物的前药用于治疗疾病的用途
|
WO2008079387A1
(en)
*
|
2006-12-21 |
2008-07-03 |
Xenoport, Inc. |
Catechol protected levodopa diester prodrugs, compositions, and methods of use
|
CA2673336A1
(en)
|
2006-12-21 |
2008-06-26 |
Xenoport, Inc. |
Levodopa dimethyl-substituted diester prodrugs, compositions, and methods of use
|
US20080265343A1
(en)
*
|
2007-04-26 |
2008-10-30 |
International Business Machines Corporation |
Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof
|
EP2222281B1
(en)
|
2007-12-20 |
2018-12-05 |
Evonik Corporation |
Process for preparing microparticles having a low residual solvent volume
|
US8940315B2
(en)
*
|
2008-04-18 |
2015-01-27 |
Medtronic, Inc. |
Benzodiazepine formulation in a polyorthoester carrier
|
US8956642B2
(en)
*
|
2008-04-18 |
2015-02-17 |
Medtronic, Inc. |
Bupivacaine formulation in a polyorthoester carrier
|
US20110201869A1
(en)
*
|
2008-05-07 |
2011-08-18 |
Obj Limited |
Method and apparatus for enhanced transdermal diffusion
|
US20100120811A1
(en)
|
2008-07-17 |
2010-05-13 |
Peter Hanson |
Long-acting injectable analgesic formulations for animals
|
EP2147684A1
(en)
|
2008-07-22 |
2010-01-27 |
Bracco Imaging S.p.A |
Diagnostic Agents Selective Against Metalloproteases
|
US8399513B2
(en)
*
|
2008-10-20 |
2013-03-19 |
Xenoport, Inc. |
Levodopa prodrug mesylate hydrate
|
JP2012505885A
(ja)
*
|
2008-10-20 |
2012-03-08 |
ゼノポート,インコーポレーテッド |
レボドパエステルプロドラッグを合成する方法
|
AU2009324545A1
(en)
*
|
2008-12-11 |
2011-06-30 |
A.P. Pharma, Inc. |
Methods for enhancing stability of polyorthoesters and their formulations
|
ES2921527T3
(es)
|
2009-06-03 |
2022-08-29 |
Forsight Vision5 Inc |
Administración de fármaco en segmento anterior
|
WO2011028234A1
(en)
*
|
2009-09-04 |
2011-03-10 |
Xenoport, Inc. |
Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
|
US8709489B2
(en)
*
|
2009-09-30 |
2014-04-29 |
Surmodics, Inc. |
Emulsions containing arylboronic acids and medical articles made therefrom
|
SG10201406420XA
(en)
|
2009-10-14 |
2014-11-27 |
Univ Nanyang Tech |
Antiproliferative agent
|
AU2010315892B2
(en)
|
2009-11-09 |
2014-09-18 |
Xenoport, Inc. |
Pharmaceutical compositions and oral dosage forms of a levodopa prodrug and methods of use
|
EP2343046A1
(en)
|
2010-01-08 |
2011-07-13 |
Nirvana's Tree House B.V. |
Functionalised triblock copolymers and compositions containing such polymers
|
WO2011146978A1
(en)
|
2010-05-25 |
2011-12-01 |
International Scientific Pty Ltd |
Delivery of oral care products
|
US8939948B2
(en)
|
2010-06-01 |
2015-01-27 |
Forsight Vision5, Inc. |
Ocular insert apparatus and methods
|
JP6046609B2
(ja)
|
2010-06-17 |
2016-12-21 |
インターナショナル・サイエンティフィック・プロプライエタリー・リミテッド |
皮膚ケア製品の送達
|
DK2621282T3
(da)
|
2010-09-28 |
2020-05-04 |
Univ California |
Gaba-agonister i behandlingen af forstyrrelser forbundet med metabolisk syndrom og gaba-kombinationer i behandling eller profylakse af type i diabetes
|
US8580294B2
(en)
|
2010-10-19 |
2013-11-12 |
International Partnership For Microbicides |
Platinum-catalyzed intravaginal rings
|
EP2678068A4
(en)
|
2011-02-23 |
2014-10-01 |
Ams Res Corp |
ACTIVE EXTRACTING BASIN TREATMENT SYSTEM AND METHOD
|
WO2012116182A1
(en)
|
2011-02-23 |
2012-08-30 |
Ams Research Corporation |
Pelvic implant and therapeutic agent system and method
|
US9301920B2
(en)
|
2012-06-18 |
2016-04-05 |
Therapeuticsmd, Inc. |
Natural combination hormone replacement formulations and therapies
|
LT2782584T
(lt)
|
2011-11-23 |
2021-09-10 |
Therapeuticsmd, Inc. |
Natūralios kombinuotos pakaitinės hormonų terapijos kompozicijos ir gydymas
|
EP2814803A4
(en)
|
2011-12-14 |
2015-11-11 |
Indicator Systems International Inc |
TRISUBSTITUTED METHYL ALCOHOLS AND POLYMERIZABLE DERIVATIVES THEREOF
|
US20150196640A1
(en)
|
2012-06-18 |
2015-07-16 |
Therapeuticsmd, Inc. |
Progesterone formulations having a desirable pk profile
|
US10806697B2
(en)
|
2012-12-21 |
2020-10-20 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
US10806740B2
(en)
|
2012-06-18 |
2020-10-20 |
Therapeuticsmd, Inc. |
Natural combination hormone replacement formulations and therapies
|
US20130338122A1
(en)
|
2012-06-18 |
2013-12-19 |
Therapeuticsmd, Inc. |
Transdermal hormone replacement therapies
|
CN104884006B
(zh)
|
2012-10-26 |
2017-12-15 |
弗赛特影像5股份有限公司 |
用于持续释放药物到眼睛的眼科系统
|
US10537581B2
(en)
|
2012-12-21 |
2020-01-21 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
US11266661B2
(en)
|
2012-12-21 |
2022-03-08 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
US9180091B2
(en)
|
2012-12-21 |
2015-11-10 |
Therapeuticsmd, Inc. |
Soluble estradiol capsule for vaginal insertion
|
US10568891B2
(en)
|
2012-12-21 |
2020-02-25 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
US10471072B2
(en)
|
2012-12-21 |
2019-11-12 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
US11246875B2
(en)
|
2012-12-21 |
2022-02-15 |
Therapeuticsmd, Inc. |
Vaginal inserted estradiol pharmaceutical compositions and methods
|
US9849180B2
(en)
|
2014-09-15 |
2017-12-26 |
Hui Rong Shen |
Long-acting semi-solid lipid formulations
|
US10220093B2
(en)
|
2013-02-28 |
2019-03-05 |
Mira Pharma Corporation |
Long-acting semi-solid lipid formulations
|
CN105358129A
(zh)
|
2013-03-15 |
2016-02-24 |
赫伦治疗有限公司 |
聚原酸酯和质子惰性溶剂的组合物
|
US10137031B2
(en)
|
2013-11-14 |
2018-11-27 |
International Partnership For Microbicides, Inc. |
Combination therapy intravaginal rings
|
DK3134068T3
(da)
|
2014-04-21 |
2021-10-04 |
Heron Therapeutics Inc |
Langtidsvirkende polymerafgivelsessystemer
|
US11083730B2
(en)
|
2014-04-21 |
2021-08-10 |
Heron Therapeutics, Inc. |
Long-acting polymeric delivery systems
|
PL3134070T3
(pl)
|
2014-04-21 |
2021-07-05 |
Heron Therapeutics, Inc. |
Kompozycje poliortoestru i kwasu organicznego jako substancji pomocniczej
|
US9801945B2
(en)
|
2014-04-21 |
2017-10-31 |
Heron Therapeutics, Inc. |
Long-acting polymeric delivery systems
|
AU2015264003A1
(en)
|
2014-05-22 |
2016-11-17 |
Therapeuticsmd, Inc. |
Natural combination hormone replacement formulations and therapies
|
US20170239286A1
(en)
|
2014-06-11 |
2017-08-24 |
International Scientific Pty Ltd. |
Device and method to treat or prevent joint degeneration
|
CA2936741C
(en)
|
2014-10-31 |
2018-11-06 |
Purdue Pharma |
Methods and compositions particularly for treatment of attention deficit disorder
|
EP3283004A4
(en)
|
2015-04-13 |
2018-12-05 |
Forsight Vision5, Inc. |
Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
|
US10328087B2
(en)
|
2015-07-23 |
2019-06-25 |
Therapeuticsmd, Inc. |
Formulations for solubilizing hormones
|
GB2556817B
(en)
|
2015-10-01 |
2019-11-06 |
Elysium Therapeutics Inc |
Polysubunit opioid prodrugs resistant to overdose and abuse
|
US10335406B2
(en)
|
2015-10-01 |
2019-07-02 |
Elysium Therapeutics, Inc. |
Opioid compositions resistant to overdose and abuse
|
US10519442B2
(en)
|
2016-02-11 |
2019-12-31 |
City Of Hope |
Twist signaling inhibitor compositions and methods of using the same
|
WO2017173071A1
(en)
|
2016-04-01 |
2017-10-05 |
Therapeuticsmd, Inc. |
Steroid hormone pharmaceutical composition
|
US10286077B2
(en)
|
2016-04-01 |
2019-05-14 |
Therapeuticsmd, Inc. |
Steroid hormone compositions in medium chain oils
|
WO2017222834A1
(en)
|
2016-06-10 |
2017-12-28 |
City Of Hope |
Compositions and methods for mitochondrial genome editing
|
US10646540B2
(en)
|
2016-11-18 |
2020-05-12 |
City Of Hope |
Peptide inhibitors of twist
|
CA3056239C
(en)
|
2017-03-17 |
2023-09-12 |
Elysium Therapeutics, Inc. |
Polysubunit opioid prodrugs resistant to overdose and abuse
|
EP3615545B1
(en)
|
2017-04-24 |
2021-09-01 |
Cocrystal Pharma, Inc. |
Pyrrolopyrimidine derivatives useful as inhibitors of influenza virus replication
|
SG11201912185XA
(en)
|
2017-06-16 |
2020-01-30 |
Avery Therapeutics Inc |
Three dimensional tissue compositions and methods of use
|
US11426418B2
(en)
|
2017-12-06 |
2022-08-30 |
Mira Pharma Corporation |
Injectable long-acting semi-solid gel formulations
|
US10561606B2
(en)
|
2017-12-06 |
2020-02-18 |
Mira Pharma Corporation |
Injectable long-acting local anesthetic semi-solid gel formulations
|
CN112638477B
(zh)
|
2018-07-27 |
2024-01-26 |
共晶制药公司 |
作为流感病毒复制的抑制剂的吡咯并[2,3-b]吡啶衍生物
|
EP3849978B1
(en)
|
2018-09-10 |
2022-11-02 |
Cocrystal Pharma, Inc. |
Pyridopyrazine and pyridotriazine inhibitors of influenza virus replication
|
MX2021004215A
(es)
|
2018-10-17 |
2021-07-15 |
Cocrystal Pharma Inc |
Combinaciones de inhibidores de la replicación del virus de la gripe.
|
US10722473B2
(en)
|
2018-11-19 |
2020-07-28 |
Purdue Pharma L.P. |
Methods and compositions particularly for treatment of attention deficit disorder
|
WO2020112716A1
(en)
|
2018-11-26 |
2020-06-04 |
Cocrystal Pharma, Inc. |
Inhibitors of influenza virus replication
|
KR20220140711A
(ko)
|
2020-01-13 |
2022-10-18 |
듀렉트 코퍼레이션 |
불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법
|
US11633405B2
(en)
|
2020-02-07 |
2023-04-25 |
Therapeuticsmd, Inc. |
Steroid hormone pharmaceutical formulations
|
WO2021188620A1
(en)
|
2020-03-17 |
2021-09-23 |
Cocrystal Pharma Inc. |
Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication
|
TW202204318A
(zh)
|
2020-04-10 |
2022-02-01 |
美商共結晶製藥公司 |
諾羅病毒及冠狀病毒複製之抑制劑
|
KR20240055745A
(ko)
|
2021-08-03 |
2024-04-29 |
코크리스탈 파마, 아이엔씨. |
코로나바이러스 억제제
|