DE2547205C2 - 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung - Google Patents

2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung

Info

Publication number
DE2547205C2
DE2547205C2 DE2547205A DE2547205A DE2547205C2 DE 2547205 C2 DE2547205 C2 DE 2547205C2 DE 2547205 A DE2547205 A DE 2547205A DE 2547205 A DE2547205 A DE 2547205A DE 2547205 C2 DE2547205 C2 DE 2547205C2
Authority
DE
Germany
Prior art keywords
decane
formula
dioxatricyclo
hydroxy
acetoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2547205A
Other languages
German (de)
English (en)
Other versions
DE2547205A1 (de
Inventor
Akiji Dipl.-Chem. 3015 Wennigsen Asai
Peter Willibrord Dr. 3000 Hannover Thies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AbbVie Pharmaceuticals GmbH
Original Assignee
Kali Chemie Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma GmbH filed Critical Kali Chemie Pharma GmbH
Priority to DE2547205A priority Critical patent/DE2547205C2/de
Priority to DE19752560493 priority patent/DE2560493C2/de
Priority to NL7609625A priority patent/NL7609625A/xx
Priority to GB37065/76A priority patent/GB1560652A/en
Priority to GB2222/79A priority patent/GB1560653A/en
Priority to FI762572A priority patent/FI762572A7/fi
Priority to MX764893U priority patent/MX4958E/es
Priority to IE2082/76A priority patent/IE43872B1/en
Priority to ZA765642A priority patent/ZA765642B/xx
Priority to IE910/80A priority patent/IE43873B1/en
Priority to IL50554A priority patent/IL50554A/xx
Priority to CH1214176A priority patent/CH622021A5/de
Priority to AU18206/76A priority patent/AU505725B2/en
Priority to AT731376A priority patent/AT346853B/de
Priority to CS766409A priority patent/CS203993B2/cs
Priority to HU76KA1473A priority patent/HU176688B/hu
Priority to PT65685A priority patent/PT65685B/pt
Priority to ES452174A priority patent/ES452174A1/es
Priority to SE7611269A priority patent/SE421696B/xx
Priority to BE6045715A priority patent/BE847302A/xx
Priority to US05/732,791 priority patent/US4089971A/en
Priority to PH19015A priority patent/PH14457A/en
Priority to FR7631241A priority patent/FR2361876A1/fr
Priority to DD7600195372A priority patent/DD128704A5/xx
Priority to PL1976193182A priority patent/PL110266B1/pl
Priority to CA263,888A priority patent/CA1095060A/en
Priority to GR51990A priority patent/GR72587B/el
Priority to DK475376A priority patent/DK475376A/da
Priority to NO763586A priority patent/NO145239C/no
Priority to YU02584/76A priority patent/YU258476A/xx
Priority to JP51127127A priority patent/JPS5251399A/ja
Priority to NO770319A priority patent/NO770319L/no
Priority to FR7707631A priority patent/FR2329669A1/fr
Priority to ES457808A priority patent/ES457808A1/es
Publication of DE2547205A1 publication Critical patent/DE2547205A1/de
Priority to AT153378A priority patent/AT349030B/de
Priority to US05/884,854 priority patent/US4189437A/en
Priority to US06/051,499 priority patent/US4256642A/en
Application granted granted Critical
Publication of DE2547205C2 publication Critical patent/DE2547205C2/de
Priority to JP60272661A priority patent/JPS61218583A/ja
Priority to JP60272660A priority patent/JPS61218591A/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE2547205A 1975-10-22 1975-10-22 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung Expired DE2547205C2 (de)

Priority Applications (39)

Application Number Priority Date Filing Date Title
DE2547205A DE2547205C2 (de) 1975-10-22 1975-10-22 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung
DE19752560493 DE2560493C2 (de) 1975-10-22 1975-10-22 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane
NL7609625A NL7609625A (nl) 1975-10-22 1976-08-30 Werkwijze ter bereiding van 2,9-dioxatricyclo (4,3,1,03'7) decanen.
GB37065/76A GB1560652A (en) 1975-10-22 1976-09-07 2,9 - dioxatriclo((4,3,1,03,7) decanes and process for their preparation
GB2222/79A GB1560653A (en) 1975-10-22 1976-09-07 4 - acetoxy - 8 - hydroxy - 3-halomethyl - 10 - methylene -2,9 - dioxatricycl(4,3,1,03,7) decanes and process for their preparation
FI762572A FI762572A7 (enExample) 1975-10-22 1976-09-07
MX764893U MX4958E (es) 1975-10-22 1976-09-08 Procedimiento para preparar 2,9 dioxatriciclo(4,3,1,03,7)decano
ZA765642A ZA765642B (en) 1975-10-22 1976-09-21 Novel 2,9-dioxatricyclo decane compounds their intermediates and processes for preparing these
IE2082/76A IE43872B1 (en) 1975-10-22 1976-09-21 2,9-dioxatricyclo/4,3,1,03.7/decanes and process for their preparation
IE910/80A IE43873B1 (en) 1975-10-22 1976-09-21 4-acetoxy-8-hydroxy-3-halomethyl-10-methylene-2,9-dioxatricyclo /4,3,1,03.7/decanes and process for their preparation
IL50554A IL50554A (en) 1975-10-22 1976-09-24 2,9-dioxatricyclodecanes,their preparation and pharmaceutical compositions containing them
CH1214176A CH622021A5 (enExample) 1975-10-22 1976-09-24
AU18206/76A AU505725B2 (en) 1975-10-22 1976-09-29 2, 9-dioxatricyclo ( 4,3,1,03,70 dercanes
AT731376A AT346853B (de) 1975-10-22 1976-10-01 Verfahren zur herstellung von neuen 2,9- dioxatricyclo(4,3,1,03,7)decanen
CS766409A CS203993B2 (en) 1975-10-22 1976-10-04 Method of producing 2,9-dioxatricyclo /4,3,1,oup 3,7/dececanes
HU76KA1473A HU176688B (en) 1975-10-22 1976-10-06 Process for preparing 2,9-dioxa-tricyclo/4,3,1,0 high 3,7/decanes
PT65685A PT65685B (en) 1975-10-22 1976-10-07 A process for the preparation of 2,9-dioxatricyclo /4,3,1,03,7/ decanes as well as intermediate products thereof
ES452174A ES452174A1 (es) 1975-10-22 1976-10-07 Procedimiento de preparacion de 2,9-dioxatriciclo (4,3,1, 03,7) decanos.
SE7611269A SE421696B (sv) 1975-10-22 1976-10-11 Sett att framstella 2,9-dioxatricyklo-(4,3,1,0?723,?727)-dekaner
BE6045715A BE847302A (fr) 1975-10-22 1976-10-14 2,9-dioxatricyclo (4, 3, 1, 0,3,7) decanes, procede pour leur preparation ainsi que les produits intermediaires convenant a cet effet
US05/732,791 US4089971A (en) 1975-10-22 1976-10-15 Pharmaceutically active 2,9-dioxatricyclo[4,3,1,03,7 ]decanes
PH19015A PH14457A (en) 1975-10-22 1976-10-18 2,9-dioxatricyclo(4,3,1,03,7)decanes and method of preparation thereof
FR7631241A FR2361876A1 (fr) 1975-10-22 1976-10-18 2,9-dioxatricyclo(4,3,1,03,7)decanes, procede pour leur preparation ainsi que les produits intermediaires convenant a cet effet
DD7600195372A DD128704A5 (de) 1975-10-22 1976-10-20 Verfahren zur herstellung von 2,9-dioxatricyclo(4,3,1,0 hoch 3,hoch 7)decanen
CA263,888A CA1095060A (en) 1975-10-22 1976-10-21 Pharmaceutically active 2,9-dioxatricyclo [4,3,1, 0.sup.3,.sup.7] decanes
GR51990A GR72587B (enExample) 1975-10-22 1976-10-21
DK475376A DK475376A (da) 1975-10-22 1976-10-21 Fremgangsmade til fremstilling af 2,9-dioxatricyclo/4,3,1,03,7/decan-forbindelser
NO763586A NO145239C (no) 1975-10-22 1976-10-21 Analogifremgangsmaate ved fremstilling av analgetisk virksomme 2,9-dioxatricyclo-(4.3.1.0 3,7)-decaner
YU02584/76A YU258476A (en) 1975-10-22 1976-10-21 Process for preparing 2,9-dioxa-triyclo-4,3,1,0,3,7,-decanes
PL1976193182A PL110266B1 (en) 1975-10-22 1976-10-21 Method of producing new 2,9-dioxatricyclo/4,3,1,0 gora 3,7/decanes
JP51127127A JPS5251399A (en) 1975-10-22 1976-10-22 Production of 2*99 dioxatricyclo *4*3*1*0137* decane
NO770319A NO770319L (enExample) 1975-10-22 1977-02-01
FR7707631A FR2329669A1 (fr) 1975-10-22 1977-03-15 2,9-dioxatricyclo(4,3,1,0 3,7)decanes et procedes pour leur preparation
ES457808A ES457808A1 (es) 1975-10-22 1977-04-14 Procedimiento de preparacion de 4-acetoxi-8-hidroxi-3-yodo- metil-10-metilen-2,9-dioxatriciclo (4,3,1,0,7) decano.
AT153378A AT349030B (de) 1975-10-22 1978-03-03 Verfahren zur herstellung von neuen 8-hydroxy- 3-halogenmethyl-4-acetoxy-10-methylen-2,9- dioxatricyclo(4,3,1,03,7)decanen bzw. der entsprechenden 8-oxo-derivate
US05/884,854 US4189437A (en) 1975-10-22 1978-03-09 Pharmaceutically active 2,9-dioxatricyclo[4,3,1,03,7 ]decanes
US06/051,499 US4256642A (en) 1975-10-22 1979-06-25 Pharmaceutically active 2,9-dioxatricyclo[4,3,1,03,7 ] decanes
JP60272661A JPS61218583A (ja) 1975-10-22 1985-12-05 ２−オキサビシクロ〔３，２，１〕オクト−３−エン
JP60272660A JPS61218591A (ja) 1975-10-22 1985-12-05 ２，９−ジオキサトリシクロ〔４，３，１，０３，７〕デカン

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2547205A DE2547205C2 (de) 1975-10-22 1975-10-22 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung

Publications (2)

Publication Number Publication Date
DE2547205A1 DE2547205A1 (de) 1977-05-05
DE2547205C2 true DE2547205C2 (de) 1983-12-08

Family

ID=5959735

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2547205A Expired DE2547205C2 (de) 1975-10-22 1975-10-22 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung

Country Status (28)

Country Link
US (2) US4089971A (enExample)
JP (3) JPS5251399A (enExample)
AT (1) AT346853B (enExample)
AU (1) AU505725B2 (enExample)
BE (1) BE847302A (enExample)
CA (1) CA1095060A (enExample)
CH (1) CH622021A5 (enExample)
CS (1) CS203993B2 (enExample)
DD (1) DD128704A5 (enExample)
DE (1) DE2547205C2 (enExample)
DK (1) DK475376A (enExample)
ES (2) ES452174A1 (enExample)
FI (1) FI762572A7 (enExample)
FR (2) FR2361876A1 (enExample)
GB (2) GB1560653A (enExample)
GR (1) GR72587B (enExample)
HU (1) HU176688B (enExample)
IE (1) IE43872B1 (enExample)
IL (1) IL50554A (enExample)
MX (1) MX4958E (enExample)
NL (1) NL7609625A (enExample)
NO (1) NO145239C (enExample)
PH (1) PH14457A (enExample)
PL (1) PL110266B1 (enExample)
PT (1) PT65685B (enExample)
SE (1) SE421696B (enExample)
YU (1) YU258476A (enExample)
ZA (1) ZA765642B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2607106C2 (de) 1976-02-21 1986-01-16 Kali-Chemie Pharma Gmbh, 3000 Hannover 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2547205C2 (de) * 1975-10-22 1983-12-08 Kali-Chemie Pharma Gmbh, 3000 Hannover 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung
US4158061A (en) * 1976-02-21 1979-06-12 Kali-Chemie Pharma Gmbh 2,9-Dioxatricyclo[4,3,1,03,7 ] decane derivatives, processes for their preparation and pharmaceutical compositions thereof
DE2730988A1 (de) 1977-07-08 1979-01-25 Kali Chemie Pharma Gmbh 3-azidomethyl-2,9-dioxatricyclo eckige klammer auf 4,3,1,0 hoch 3,7 eckige klammer zu decane und verfahren zu deren herstellung
US4677190A (en) * 1986-05-09 1987-06-30 University Patents, Inc. Synthesis and ring-opening polymerization of bicyclic lactones containing a tetrahydropyran ring

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759840A (fr) 1969-12-08 1971-05-17 Kali Chemie Ag 2,9-dioxatricyclo-(4,3,1,0,3,7)-decanes et procede pour les preparer
US3917651A (en) * 1969-12-08 1975-11-04 Kali Chemie Ag Dioxatricyclodecanones
US3812154A (en) * 1969-12-08 1974-05-21 Kali Chemie Ag Dioxatricyclodecanes
US4016176A (en) * 1973-02-08 1977-04-05 Kali-Chemie Pharma Gmbh Esters of 4-hydroxy-2,9-dioxatricyclo[4.3.1.03,7 ] decanes and processes for their production
US4189437A (en) * 1975-10-22 1980-02-19 Kali-Chemie Pharma Gmbh Pharmaceutically active 2,9-dioxatricyclo[4,3,1,03,7 ]decanes
DE2547205C2 (de) * 1975-10-22 1983-12-08 Kali-Chemie Pharma Gmbh, 3000 Hannover 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung
US4158061A (en) * 1976-02-21 1979-06-12 Kali-Chemie Pharma Gmbh 2,9-Dioxatricyclo[4,3,1,03,7 ] decane derivatives, processes for their preparation and pharmaceutical compositions thereof
DE2704621A1 (de) * 1977-02-04 1978-08-10 Kali Chemie Pharma Gmbh 2,9-dioxatricyclo eckige klammer auf 4,3,1,0 hoch 3,7 eckige klammer zu decane und verfahren zu deren herstellung
DE2719916C2 (de) * 1977-05-04 1987-03-19 Kali-Chemie Pharma Gmbh, 3000 Hannover Verfahren zur Herstellung von 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decanen
US4117148A (en) * 1977-02-18 1978-09-26 Kali-Chemie Pharma Gmbh. 2,9-Dioxatricyclo [4,3,1,0,3,7] decane derivatives, processes for their preparation and pharmaceutical compositions thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS-ERMITTELT

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2607106C2 (de) 1976-02-21 1986-01-16 Kali-Chemie Pharma Gmbh, 3000 Hannover 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
HU176688B (en) 1981-04-28
JPS61218583A (ja) 1986-09-29
GR72587B (enExample) 1983-11-18
NO145239B (no) 1981-11-02
DK475376A (da) 1977-04-23
PT65685B (en) 1978-04-14
PL110266B1 (en) 1980-07-31
ATA731376A (de) 1978-04-15
GB1560653A (en) 1980-02-06
IL50554A0 (en) 1976-11-30
FR2329669A1 (fr) 1977-05-27
PH14457A (en) 1981-07-29
FR2361876A1 (fr) 1978-03-17
JPS621950B2 (enExample) 1987-01-16
FR2329669B1 (enExample) 1981-06-12
CA1095060A (en) 1981-02-03
JPS5251399A (en) 1977-04-25
DE2547205A1 (de) 1977-05-05
PT65685A (en) 1976-11-01
US4089971A (en) 1978-05-16
ES457808A1 (es) 1978-03-01
AU505725B2 (en) 1979-11-29
BE847302A (fr) 1977-01-31
SE421696B (sv) 1982-01-25
YU258476A (en) 1982-08-31
FR2361876B1 (enExample) 1978-12-22
NO763586L (enExample) 1977-04-25
ZA765642B (en) 1977-08-31
SE7611269L (sv) 1977-04-23
AU1820676A (en) 1978-04-06
AT346853B (de) 1978-11-27
JPS61218591A (ja) 1986-09-29
DD128704A5 (de) 1977-12-07
JPS6123191B2 (enExample) 1986-06-04
CS203993B2 (en) 1981-03-31
NL7609625A (nl) 1977-04-26
IE43872L (en) 1977-04-22
IL50554A (en) 1980-07-31
NO145239C (no) 1982-02-10
FI762572A7 (enExample) 1977-04-23
CH622021A5 (enExample) 1981-03-13
IE43872B1 (en) 1981-06-17
GB1560652A (en) 1980-02-06
US4256642A (en) 1981-03-17
MX4958E (es) 1983-01-18
ES452174A1 (es) 1977-10-16

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