ES457808A1 - Procedimiento de preparacion de 4-acetoxi-8-hidroxi-3-yodo- metil-10-metilen-2,9-dioxatriciclo (4,3,1,0,7) decano. - Google Patents

Procedimiento de preparacion de 4-acetoxi-8-hidroxi-3-yodo- metil-10-metilen-2,9-dioxatriciclo (4,3,1,0,7) decano.

Info

Publication number
ES457808A1
ES457808A1 ES457808A ES457808A ES457808A1 ES 457808 A1 ES457808 A1 ES 457808A1 ES 457808 A ES457808 A ES 457808A ES 457808 A ES457808 A ES 457808A ES 457808 A1 ES457808 A1 ES 457808A1
Authority
ES
Spain
Prior art keywords
dioxatricyclo
decanes
pharmaceutically active
disclosed
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES457808A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Products GmbH
Original Assignee
Kali Chemie Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma GmbH filed Critical Kali Chemie Pharma GmbH
Publication of ES457808A1 publication Critical patent/ES457808A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Procedimiento de preparación de 4-acetoxi-8-hidroxi-3-yodometil-10-metilen-2,9-dioxatriciclo[4,3,1,0^3,7] decano (fórmula II): ***1 (Ver fórmula1) caracterizado porque se hacen reaccionar didrovaltrato u extractos que contienen didrovaltrato con halogenuros de hidrógeno en ácido acético glacial.
ES457808A 1975-10-22 1977-04-14 Procedimiento de preparacion de 4-acetoxi-8-hidroxi-3-yodo- metil-10-metilen-2,9-dioxatriciclo (4,3,1,0,7) decano. Expired ES457808A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2547205A DE2547205C2 (de) 1975-10-22 1975-10-22 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
ES457808A1 true ES457808A1 (es) 1978-03-01

Family

ID=5959735

Family Applications (2)

Application Number Title Priority Date Filing Date
ES452174A Expired ES452174A1 (es) 1975-10-22 1976-10-07 Procedimiento de preparacion de 2,9-dioxatriciclo (4,3,1, 03,7) decanos.
ES457808A Expired ES457808A1 (es) 1975-10-22 1977-04-14 Procedimiento de preparacion de 4-acetoxi-8-hidroxi-3-yodo- metil-10-metilen-2,9-dioxatriciclo (4,3,1,0,7) decano.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES452174A Expired ES452174A1 (es) 1975-10-22 1976-10-07 Procedimiento de preparacion de 2,9-dioxatriciclo (4,3,1, 03,7) decanos.

Country Status (28)

Country Link
US (2) US4089971A (es)
JP (3) JPS5251399A (es)
AT (1) AT346853B (es)
AU (1) AU505725B2 (es)
BE (1) BE847302A (es)
CA (1) CA1095060A (es)
CH (1) CH622021A5 (es)
CS (1) CS203993B2 (es)
DD (1) DD128704A5 (es)
DE (1) DE2547205C2 (es)
DK (1) DK475376A (es)
ES (2) ES452174A1 (es)
FI (1) FI762572A (es)
FR (2) FR2361876A1 (es)
GB (2) GB1560652A (es)
GR (1) GR72587B (es)
HU (1) HU176688B (es)
IE (1) IE43872B1 (es)
IL (1) IL50554A (es)
MX (1) MX4958E (es)
NL (1) NL7609625A (es)
NO (1) NO145239C (es)
PH (1) PH14457A (es)
PL (1) PL110266B1 (es)
PT (1) PT65685B (es)
SE (1) SE421696B (es)
YU (1) YU258476A (es)
ZA (1) ZA765642B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2547205C2 (de) * 1975-10-22 1983-12-08 Kali-Chemie Pharma Gmbh, 3000 Hannover 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung
US4158061A (en) * 1976-02-21 1979-06-12 Kali-Chemie Pharma Gmbh 2,9-Dioxatricyclo[4,3,1,03,7 ] decane derivatives, processes for their preparation and pharmaceutical compositions thereof
DE2607106C2 (de) 1976-02-21 1986-01-16 Kali-Chemie Pharma Gmbh, 3000 Hannover 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung
DE2730988A1 (de) 1977-07-08 1979-01-25 Kali Chemie Pharma Gmbh 3-azidomethyl-2,9-dioxatricyclo eckige klammer auf 4,3,1,0 hoch 3,7 eckige klammer zu decane und verfahren zu deren herstellung
US4677190A (en) * 1986-05-09 1987-06-30 University Patents, Inc. Synthesis and ring-opening polymerization of bicyclic lactones containing a tetrahydropyran ring

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917651A (en) * 1969-12-08 1975-11-04 Kali Chemie Ag Dioxatricyclodecanones
BE759840A (fr) 1969-12-08 1971-05-17 Kali Chemie Ag 2,9-dioxatricyclo-(4,3,1,0,3,7)-decanes et procede pour les preparer
US3812154A (en) * 1969-12-08 1974-05-21 Kali Chemie Ag Dioxatricyclodecanes
US4016176A (en) * 1973-02-08 1977-04-05 Kali-Chemie Pharma Gmbh Esters of 4-hydroxy-2,9-dioxatricyclo[4.3.1.03,7 ] decanes and processes for their production
DE2547205C2 (de) * 1975-10-22 1983-12-08 Kali-Chemie Pharma Gmbh, 3000 Hannover 2,9-Dioxatricyclo[4,3,1,0↑3↑↑,↑↑7↑]decane und Verfahren zu deren Herstellung
US4189437A (en) * 1975-10-22 1980-02-19 Kali-Chemie Pharma Gmbh Pharmaceutically active 2,9-dioxatricyclo[4,3,1,03,7 ]decanes
US4158061A (en) * 1976-02-21 1979-06-12 Kali-Chemie Pharma Gmbh 2,9-Dioxatricyclo[4,3,1,03,7 ] decane derivatives, processes for their preparation and pharmaceutical compositions thereof
DE2704621A1 (de) * 1977-02-04 1978-08-10 Kali Chemie Pharma Gmbh 2,9-dioxatricyclo eckige klammer auf 4,3,1,0 hoch 3,7 eckige klammer zu decane und verfahren zu deren herstellung
DE2719916A1 (de) * 1977-05-04 1978-11-09 Kali Chemie Pharma Gmbh Verfahren zur herstellung von 2,9-dioxatricyclo eckige klammer auf 4,3,1,0 hoch 3,7 eckige klammer zu decanen
US4117148A (en) * 1977-02-18 1978-09-26 Kali-Chemie Pharma Gmbh. 2,9-Dioxatricyclo [4,3,1,0,3,7] decane derivatives, processes for their preparation and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
DK475376A (da) 1977-04-23
IL50554A0 (en) 1976-11-30
IE43872B1 (en) 1981-06-17
JPS61218591A (ja) 1986-09-29
ATA731376A (de) 1978-04-15
DE2547205C2 (de) 1983-12-08
PT65685A (en) 1976-11-01
MX4958E (es) 1983-01-18
IL50554A (en) 1980-07-31
FR2361876B1 (es) 1978-12-22
JPS621950B2 (es) 1987-01-16
JPS5251399A (en) 1977-04-25
BE847302A (fr) 1977-01-31
CA1095060A (en) 1981-02-03
CH622021A5 (es) 1981-03-13
IE43872L (en) 1977-04-22
ES452174A1 (es) 1977-10-16
YU258476A (en) 1982-08-31
AT346853B (de) 1978-11-27
DD128704A5 (de) 1977-12-07
PH14457A (en) 1981-07-29
NO145239C (no) 1982-02-10
US4256642A (en) 1981-03-17
US4089971A (en) 1978-05-16
GB1560653A (en) 1980-02-06
FR2361876A1 (fr) 1978-03-17
JPS61218583A (ja) 1986-09-29
PT65685B (en) 1978-04-14
NL7609625A (nl) 1977-04-26
SE421696B (sv) 1982-01-25
HU176688B (en) 1981-04-28
GR72587B (es) 1983-11-18
CS203993B2 (en) 1981-03-31
FR2329669A1 (fr) 1977-05-27
FI762572A (es) 1977-04-23
DE2547205A1 (de) 1977-05-05
AU1820676A (en) 1978-04-06
GB1560652A (en) 1980-02-06
PL110266B1 (en) 1980-07-31
NO145239B (no) 1981-11-02
JPS6123191B2 (es) 1986-06-04
SE7611269L (sv) 1977-04-23
ZA765642B (en) 1977-08-31
FR2329669B1 (es) 1981-06-12
AU505725B2 (en) 1979-11-29
NO763586L (es) 1977-04-25

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971103