DE2362568C2 - Alkanolaminderivate und sie enthaltende pharmazeutische Zusammensetzungen - Google Patents

Alkanolaminderivate und sie enthaltende pharmazeutische Zusammensetzungen

Info

Publication number
DE2362568C2
DE2362568C2 DE2362568A DE2362568A DE2362568C2 DE 2362568 C2 DE2362568 C2 DE 2362568C2 DE 2362568 A DE2362568 A DE 2362568A DE 2362568 A DE2362568 A DE 2362568A DE 2362568 C2 DE2362568 C2 DE 2362568C2
Authority
DE
Germany
Prior art keywords
ethyl acetate
mixture
propanol
ethanol
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2362568A
Other languages
German (de)
English (en)
Other versions
DE2362568A1 (de
Inventor
Leslie Harold Macclesfield Cheshire Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of DE2362568A1 publication Critical patent/DE2362568A1/de
Application granted granted Critical
Publication of DE2362568C2 publication Critical patent/DE2362568C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/14—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE2362568A 1972-12-15 1973-12-17 Alkanolaminderivate und sie enthaltende pharmazeutische Zusammensetzungen Expired DE2362568C2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB5797072 1972-12-15
GB4347873A GB1455116A (en) 1972-12-15 1973-09-17 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
DE2362568A1 DE2362568A1 (de) 1974-06-20
DE2362568C2 true DE2362568C2 (de) 1983-11-03

Family

ID=26265164

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2362568A Expired DE2362568C2 (de) 1972-12-15 1973-12-17 Alkanolaminderivate und sie enthaltende pharmazeutische Zusammensetzungen

Country Status (28)

Country Link
US (2) US3928412A (OSRAM)
JP (1) JPS5919090B2 (OSRAM)
AR (2) AR213930A1 (OSRAM)
AT (3) AT345791B (OSRAM)
BE (1) BE808666A (OSRAM)
CA (1) CA1031362A (OSRAM)
CH (4) CH605668A5 (OSRAM)
CS (1) CS187389B2 (OSRAM)
DD (1) DD113349A5 (OSRAM)
DE (1) DE2362568C2 (OSRAM)
DK (1) DK158466C (OSRAM)
ES (1) ES421538A1 (OSRAM)
FI (1) FI61027C (OSRAM)
FR (1) FR2210407B1 (OSRAM)
GB (1) GB1455116A (OSRAM)
HK (1) HK24480A (OSRAM)
HU (1) HU169087B (OSRAM)
IE (1) IE38602B1 (OSRAM)
IL (1) IL43795A (OSRAM)
IN (1) IN139418B (OSRAM)
KE (1) KE3030A (OSRAM)
LU (1) LU68997A1 (OSRAM)
MY (1) MY8100035A (OSRAM)
NL (1) NL179203C (OSRAM)
NO (1) NO138335C (OSRAM)
SE (1) SE408794B (OSRAM)
SU (2) SU576917A3 (OSRAM)
YU (2) YU40097B (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4425362A (en) 1980-11-06 1984-01-10 Sandoz Ltd. 3-Aminopropoxyphenyl derivatives and pharmaceutical compositions containing them

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038313A (en) * 1970-01-08 1977-07-26 Ciba-Geigy Corporation Cycloalkylureido phenoxy propanolamines
US4167581A (en) * 1972-12-15 1979-09-11 Imperial Chemical Industries Limited Alkanolamine derivatives and pharmaceutical compositions and uses thereof
US4171374A (en) * 1972-12-15 1979-10-16 Imperial Chemical Industries Limited Alkanolamine derivatives
US4117157A (en) * 1973-06-22 1978-09-26 Imperial Chemical Industries Limited Ethanolamine derivatives having β-adrenergic blocking activity
US4034112A (en) * 1973-06-22 1977-07-05 Imperial Chemical Industries Limited Ethanolamine derivatives having β-adrenergic blocking activity
US4041074A (en) * 1973-07-19 1977-08-09 Imperial Chemical Industries Limited 1-Hydroxyaryl-2-amidoalkylaminoethanol derivatives
GB1573359A (en) * 1977-12-20 1980-08-20 Ici Ltd Alkanolamine derivatives
GB1509527A (en) * 1974-06-05 1978-05-04 Ici Ltd 1-(aryl-or heteroaryl)oxy-3-(substituted-amino)propan-2-ol derivatives processes for their manufacture and pharmaceutical compositions containing them
US4041075A (en) * 1973-12-12 1977-08-09 Imperial Chemical Industries Limited Phenoxy-alkanolamine derivatives
AT334385B (de) * 1973-12-20 1976-01-10 Chemie Linz Ag Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen
US4141987A (en) * 1974-06-05 1979-02-27 Imperial Chemical Industries Limited 1-Aryloxy-3-thenamidoalkylamino-2-propanol derivatives
US4162331A (en) * 1975-06-17 1979-07-24 Nippon Shinyaku Co., Ltd. Substituted N-(carboxymethyl)-3-aminopropan-2-ol derivatives
GB1540463A (en) * 1976-10-07 1979-02-14 Ici Ltd Alkanolamine derivatives
IE47053B1 (en) * 1977-05-23 1983-12-14 Ici Ltd Cardiac stimulants
US4172150A (en) * 1977-05-23 1979-10-23 Imperial Chemical Industries Limited Cardiac stimulants
US4219561A (en) * 1977-09-22 1980-08-26 Imperial Chemical Industries Limited Alkanolamine derivatives
US4239700A (en) * 1978-10-10 1980-12-16 Texaco Development Corp. Isatoic anhydride derivatives and use as chain-extenders
US4281189A (en) * 1979-09-06 1981-07-28 Hoffmann-La Roche Inc. Sulfonamide intermediates for adrenergic blocking agents
US4301300A (en) * 1979-09-06 1981-11-17 Hoffmann-La Roche Inc. Sulfonamide intermediates for adrenergic blocking agents
FR2477537A1 (fr) * 1980-03-07 1981-09-11 Francaise Sucrerie Nouvelles guanidines acylees, urees et urees substituees, leur procede de fabrication et leur application en tant que medicaments
EP0085286B1 (en) * 1981-12-17 1986-04-30 Aktiebolaget Hässle Para-substituted 3-phenoxy-1-carbonylaminoalkylamino-propan-2-ols having beta receptor blocking properties
CH653670A5 (de) * 1983-03-03 1986-01-15 Hoffmann La Roche Benzamid-derivate.
US5238962A (en) * 1983-03-03 1993-08-24 Hoffmann-La Roche Inc. Benzamide derivatives
US4593039A (en) * 1984-04-02 1986-06-03 Merck & Co., Inc. 1-aryloxy-3-(substituted aminoalkylamino)-2-propanols
DE3427309A1 (de) * 1984-07-25 1986-01-30 Boehringer Ingelheim KG, 6507 Ingelheim Neue 1-aryloxypropanolamine, verfahren zu ihrer herstellung und ihre verwendung
DE3512627A1 (de) * 1985-04-06 1986-10-09 Boehringer Mannheim Gmbh, 6800 Mannheim Amino-propanol-derivate, verfahren zu deren herstellung, verwendung derselben und diese enthaltende arzneimittel
JPH0825997B2 (ja) * 1985-05-14 1996-03-13 ルイス，ウィリアム・ジョン ３−アミノプロピルオキシフェニル誘導体、その製法およびそれらを含有する医薬組成物
EP0207036A1 (en) * 1985-06-20 1986-12-30 Aktiebolaget Hässle New para-substituted 3-phenoxy-1-piperidinecarbonylaminoalkylamino-propanol-2-s having beta receptor blocking properties.
GB8607313D0 (en) * 1986-03-25 1986-04-30 Ici Plc Pharmaceutical compositions
GB8607312D0 (en) * 1986-03-25 1986-04-30 Ici Plc Therapeutic agents
IE883400L (en) * 1987-11-13 1989-05-13 Fuisz Technologies Ltd Phenethanolamine derivatives
JP2004137284A (ja) * 1997-06-17 2004-05-13 Kaken Pharmaceut Co Ltd ２−スルファモイル安息香酸誘導体
GB0417802D0 (en) * 2004-08-10 2004-09-15 Novartis Ag Organic compounds
CN106977426A (zh) * 2017-05-27 2017-07-25 哈尔滨师范大学 一种腰果酚苯基脲及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes
GB1199037A (en) * 1967-09-27 1970-07-15 Ici Ltd Alkanolamine Derivatives
GB1285038A (en) * 1969-02-21 1972-08-09 Ici Ltd Alkanolamine derivatives
BE754604A (fr) * 1969-08-08 1971-02-08 Boehringer Sohn Ingelheim Le 1-(2-nitrilophenoxy)-2-hydroxy-3-ethyl-aminopropane et ses sels

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS-ERMITTELT

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4425362A (en) 1980-11-06 1984-01-10 Sandoz Ltd. 3-Aminopropoxyphenyl derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
HU169087B (OSRAM) 1976-09-28
US4010189A (en) 1977-03-01
LU68997A1 (OSRAM) 1974-02-22
US3928412A (en) 1975-12-23
FR2210407A1 (OSRAM) 1974-07-12
HK24480A (en) 1980-05-16
IL43795A (en) 1978-03-10
AT345791B (de) 1978-10-10
DD113349A5 (OSRAM) 1975-06-05
NO138335C (no) 1978-08-16
AR214288A1 (es) 1979-05-31
ES421538A1 (es) 1976-07-16
FI61027C (fi) 1982-05-10
FR2210407B1 (OSRAM) 1978-01-13
IE38602B1 (en) 1978-04-26
GB1455116A (en) 1976-11-10
ATA266376A (de) 1977-11-15
IN139418B (OSRAM) 1976-06-19
IL43795A0 (en) 1974-03-14
FI61027B (fi) 1982-01-29
CS187389B2 (en) 1979-01-31
NL179203B (nl) 1986-03-03
AR213930A1 (es) 1979-04-11
CH605666A5 (OSRAM) 1978-10-13
SE408794B (sv) 1979-07-09
CH605668A5 (OSRAM) 1978-10-13
KE3030A (en) 1980-03-14
YU42539B (en) 1988-10-31
NL179203C (nl) 1986-08-01
YU280680A (en) 1983-09-30
YU324673A (en) 1982-02-28
NO138335B (no) 1978-05-08
CH611876A5 (en) 1979-06-29
DE2362568A1 (de) 1974-06-20
JPS5919090B2 (ja) 1984-05-02
SU576917A3 (ru) 1977-10-15
MY8100035A (en) 1981-12-31
SU695555A3 (ru) 1979-10-30
AT344144B (de) 1978-07-10
ATA566077A (de) 1979-01-15
BE808666A (fr) 1974-06-14
NL7317096A (OSRAM) 1974-06-18
IE38602L (en) 1974-06-15
JPS4994638A (OSRAM) 1974-09-09
CA1031362A (en) 1978-05-16
YU40097B (en) 1985-08-31
CH605667A5 (OSRAM) 1978-10-13
DK158466B (da) 1990-05-21
DK158466C (da) 1990-10-15
AT351557B (de) 1979-08-10

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Legal Events

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Ipc: C07C103/44

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