AT344144B - Verfahren zur herstellung von neuen substituierten 3-aminoalkylamino-2-hydroxy-1-phenoxypropanen und von deren saeureadditionssalzen - Google Patents

Verfahren zur herstellung von neuen substituierten 3-aminoalkylamino-2-hydroxy-1-phenoxypropanen und von deren saeureadditionssalzen

Info

Publication number
AT344144B
AT344144B AT266376A AT266376A AT344144B AT 344144 B AT344144 B AT 344144B AT 266376 A AT266376 A AT 266376A AT 266376 A AT266376 A AT 266376A AT 344144 B AT344144 B AT 344144B
Authority
AT
Austria
Prior art keywords
phenoxypropanes
aminoalkylamino
hydroxy
production
acid addition
Prior art date
Application number
AT266376A
Other languages
English (en)
Other versions
ATA266376A (de
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of ATA266376A publication Critical patent/ATA266376A/de
Application granted granted Critical
Publication of AT344144B publication Critical patent/AT344144B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/14—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT266376A 1972-12-15 1976-04-12 Verfahren zur herstellung von neuen substituierten 3-aminoalkylamino-2-hydroxy-1-phenoxypropanen und von deren saeureadditionssalzen AT344144B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB5797072 1972-12-15
GB4347873A GB1455116A (en) 1972-12-15 1973-09-17 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
ATA266376A ATA266376A (de) 1977-11-15
AT344144B true AT344144B (de) 1978-07-10

Family

ID=26265164

Family Applications (3)

Application Number Title Priority Date Filing Date
AT581577A AT345791B (de) 1972-12-15 1973-12-17 Verfahren zur herstellung von neuen substituierten 3-aminoalkylamino-2-hydroxy-1-pheonxypropanen und von deren saeureadditionssalzen
AT266376A AT344144B (de) 1972-12-15 1976-04-12 Verfahren zur herstellung von neuen substituierten 3-aminoalkylamino-2-hydroxy-1-phenoxypropanen und von deren saeureadditionssalzen
AT566077A AT351557B (de) 1972-12-15 1977-07-29 Verfahren zur herstellung von neuen substituierten 3-aminoalkylamino-2-hydroxy-1- phenoxypropanen und von deren saeureadditions- salzen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT581577A AT345791B (de) 1972-12-15 1973-12-17 Verfahren zur herstellung von neuen substituierten 3-aminoalkylamino-2-hydroxy-1-pheonxypropanen und von deren saeureadditionssalzen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT566077A AT351557B (de) 1972-12-15 1977-07-29 Verfahren zur herstellung von neuen substituierten 3-aminoalkylamino-2-hydroxy-1- phenoxypropanen und von deren saeureadditions- salzen

Country Status (28)

Country Link
US (2) US3928412A (de)
JP (1) JPS5919090B2 (de)
AR (2) AR213930A1 (de)
AT (3) AT345791B (de)
BE (1) BE808666A (de)
CA (1) CA1031362A (de)
CH (4) CH611876A5 (de)
CS (1) CS187389B2 (de)
DD (1) DD113349A5 (de)
DE (1) DE2362568C2 (de)
DK (1) DK158466C (de)
ES (1) ES421538A1 (de)
FI (1) FI61027C (de)
FR (1) FR2210407B1 (de)
GB (1) GB1455116A (de)
HK (1) HK24480A (de)
HU (1) HU169087B (de)
IE (1) IE38602B1 (de)
IL (1) IL43795A (de)
IN (1) IN139418B (de)
KE (1) KE3030A (de)
LU (1) LU68997A1 (de)
MY (1) MY8100035A (de)
NL (1) NL179203C (de)
NO (1) NO138335C (de)
SE (1) SE408794B (de)
SU (2) SU576917A3 (de)
YU (2) YU40097B (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4038313A (en) * 1970-01-08 1977-07-26 Ciba-Geigy Corporation Cycloalkylureido phenoxy propanolamines
US4167581A (en) * 1972-12-15 1979-09-11 Imperial Chemical Industries Limited Alkanolamine derivatives and pharmaceutical compositions and uses thereof
US4171374A (en) * 1972-12-15 1979-10-16 Imperial Chemical Industries Limited Alkanolamine derivatives
US4034112A (en) * 1973-06-22 1977-07-05 Imperial Chemical Industries Limited Ethanolamine derivatives having β-adrenergic blocking activity
US4117157A (en) * 1973-06-22 1978-09-26 Imperial Chemical Industries Limited Ethanolamine derivatives having β-adrenergic blocking activity
US4041074A (en) * 1973-07-19 1977-08-09 Imperial Chemical Industries Limited 1-Hydroxyaryl-2-amidoalkylaminoethanol derivatives
GB1573359A (en) * 1977-12-20 1980-08-20 Ici Ltd Alkanolamine derivatives
US4041075A (en) * 1973-12-12 1977-08-09 Imperial Chemical Industries Limited Phenoxy-alkanolamine derivatives
AT334385B (de) * 1973-12-20 1976-01-10 Chemie Linz Ag Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen
GB1521471A (en) * 1974-06-05 1978-08-16 Randall & Son Ltd J Token-deposit locks
US4141987A (en) * 1974-06-05 1979-02-27 Imperial Chemical Industries Limited 1-Aryloxy-3-thenamidoalkylamino-2-propanol derivatives
US4162331A (en) * 1975-06-17 1979-07-24 Nippon Shinyaku Co., Ltd. Substituted N-(carboxymethyl)-3-aminopropan-2-ol derivatives
GB1540463A (en) * 1976-10-07 1979-02-14 Ici Ltd Alkanolamine derivatives
IE47053B1 (en) * 1977-05-23 1983-12-14 Ici Ltd Cardiac stimulants
US4172150A (en) * 1977-05-23 1979-10-23 Imperial Chemical Industries Limited Cardiac stimulants
US4219561A (en) * 1977-09-22 1980-08-26 Imperial Chemical Industries Limited Alkanolamine derivatives
US4239700A (en) * 1978-10-10 1980-12-16 Texaco Development Corp. Isatoic anhydride derivatives and use as chain-extenders
US4301300A (en) * 1979-09-06 1981-11-17 Hoffmann-La Roche Inc. Sulfonamide intermediates for adrenergic blocking agents
US4281189A (en) * 1979-09-06 1981-07-28 Hoffmann-La Roche Inc. Sulfonamide intermediates for adrenergic blocking agents
FR2477537A1 (fr) * 1980-03-07 1981-09-11 Francaise Sucrerie Nouvelles guanidines acylees, urees et urees substituees, leur procede de fabrication et leur application en tant que medicaments
FI76551C (fi) 1980-11-06 1988-11-10 Sandoz Ag Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-aminopropoxifenylderivat.
ATE19510T1 (de) * 1981-12-17 1986-05-15 Haessle Ab Para-substituierte 3-phenoxy-1carbonylaminoalkylaminopropan-2-ole mit blockierenden wirkungen bei betarezeptoren.
US5238962A (en) * 1983-03-03 1993-08-24 Hoffmann-La Roche Inc. Benzamide derivatives
CH653670A5 (de) * 1983-03-03 1986-01-15 Hoffmann La Roche Benzamid-derivate.
US4593039A (en) * 1984-04-02 1986-06-03 Merck & Co., Inc. 1-aryloxy-3-(substituted aminoalkylamino)-2-propanols
DE3427309A1 (de) * 1984-07-25 1986-01-30 Boehringer Ingelheim KG, 6507 Ingelheim Neue 1-aryloxypropanolamine, verfahren zu ihrer herstellung und ihre verwendung
DE3512627A1 (de) * 1985-04-06 1986-10-09 Boehringer Mannheim Gmbh, 6800 Mannheim Amino-propanol-derivate, verfahren zu deren herstellung, verwendung derselben und diese enthaltende arzneimittel
DE3687035T2 (de) * 1985-05-14 1993-03-25 William John Louis 3-aminopropyloxyphenylabkoemmlinge, herstellung und arzneitmittel die sie enthalten.
EP0207036A1 (de) * 1985-06-20 1986-12-30 Aktiebolaget Hässle Neue para-substituierte 3-Phenoxy-1-piperidincarbonylaminoalkylaminopropanole-2 mit Betablockerwirkung
GB8607313D0 (en) * 1986-03-25 1986-04-30 Ici Plc Pharmaceutical compositions
GB8607312D0 (en) * 1986-03-25 1986-04-30 Ici Plc Therapeutic agents
AU609209B2 (en) * 1987-11-13 1991-04-26 Glaxo Group Limited Phenethanolamine derivatives
JP2004137284A (ja) * 1997-06-17 2004-05-13 Kaken Pharmaceut Co Ltd ２−スルファモイル安息香酸誘導体
GB0417802D0 (en) * 2004-08-10 2004-09-15 Novartis Ag Organic compounds
CN106977426A (zh) * 2017-05-27 2017-07-25 哈尔滨师范大学 一种腰果酚苯基脲及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes
GB1199037A (en) * 1967-09-27 1970-07-15 Ici Ltd Alkanolamine Derivatives
GB1285038A (en) * 1969-02-21 1972-08-09 Ici Ltd Alkanolamine derivatives
BE754604A (fr) * 1969-08-08 1971-02-08 Boehringer Sohn Ingelheim Le 1-(2-nitrilophenoxy)-2-hydroxy-3-ethyl-aminopropane et ses sels

Also Published As

Publication number Publication date
DK158466C (da) 1990-10-15
GB1455116A (en) 1976-11-10
FR2210407A1 (de) 1974-07-12
YU324673A (en) 1982-02-28
CS187389B2 (en) 1979-01-31
NL179203B (nl) 1986-03-03
US3928412A (en) 1975-12-23
JPS4994638A (de) 1974-09-09
IL43795A0 (en) 1974-03-14
DD113349A5 (de) 1975-06-05
SU695555A3 (ru) 1979-10-30
MY8100035A (en) 1981-12-31
CH611876A5 (en) 1979-06-29
FI61027C (fi) 1982-05-10
JPS5919090B2 (ja) 1984-05-02
ATA566077A (de) 1979-01-15
CH605667A5 (de) 1978-10-13
IN139418B (de) 1976-06-19
ATA266376A (de) 1977-11-15
DE2362568C2 (de) 1983-11-03
NL179203C (nl) 1986-08-01
AR214288A1 (es) 1979-05-31
CA1031362A (en) 1978-05-16
CH605668A5 (de) 1978-10-13
IL43795A (en) 1978-03-10
YU40097B (en) 1985-08-31
YU42539B (en) 1988-10-31
LU68997A1 (de) 1974-02-22
IE38602B1 (en) 1978-04-26
NO138335C (no) 1978-08-16
YU280680A (en) 1983-09-30
FR2210407B1 (de) 1978-01-13
HU169087B (de) 1976-09-28
FI61027B (fi) 1982-01-29
NO138335B (no) 1978-05-08
AT345791B (de) 1978-10-10
HK24480A (en) 1980-05-16
SU576917A3 (ru) 1977-10-15
AT351557B (de) 1979-08-10
AR213930A1 (es) 1979-04-11
DK158466B (da) 1990-05-21
BE808666A (fr) 1974-06-14
NL7317096A (de) 1974-06-18
US4010189A (en) 1977-03-01
SE408794B (sv) 1979-07-09
DE2362568A1 (de) 1974-06-20
ES421538A1 (es) 1976-07-16
IE38602L (en) 1974-06-15
KE3030A (en) 1980-03-14
CH605666A5 (de) 1978-10-13

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Legal Events

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ELJ Ceased due to non-payment of the annual fee
ELA Expired due to lapse of time