DD252614A5 - Verfahren zur Herstellung von Hepatitis B-Oberflächenantigenen - Google Patents

Verfahren zur Herstellung von Hepatitis B-Oberflächenantigenen Download PDF

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Publication number
DD252614A5
DD252614A5 DD29662586A DD29662586A DD252614A5 DD 252614 A5 DD252614 A5 DD 252614A5 DD 29662586 A DD29662586 A DD 29662586A DD 29662586 A DD29662586 A DD 29662586A DD 252614 A5 DD252614 A5 DD 252614A5
Authority
DD
German Democratic Republic
Prior art keywords
dna
plasmid
dna fragment
fragment
hepatitis
Prior art date
Application number
DD29662586A
Other languages
German (de)
English (en)
Inventor
Juerg F Tschopp
Michael M Harpold
James M Cregg
Richard G Buckholz
Original Assignee
Phillips Petroleum Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phillips Petroleum Co filed Critical Phillips Petroleum Co
Publication of DD252614A5 publication Critical patent/DD252614A5/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DD29662586A 1985-11-26 1986-11-25 Verfahren zur Herstellung von Hepatitis B-Oberflächenantigenen DD252614A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/801,713 US4895800A (en) 1985-11-26 1985-11-26 Yeast production of hepatitis B surface antigen

Publications (1)

Publication Number Publication Date
DD252614A5 true DD252614A5 (de) 1987-12-23

Family

ID=25181867

Family Applications (1)

Application Number Title Priority Date Filing Date
DD29662586A DD252614A5 (de) 1985-11-26 1986-11-25 Verfahren zur Herstellung von Hepatitis B-Oberflächenantigenen

Country Status (28)

Country Link
US (1) US4895800A (pt)
EP (1) EP0226846B1 (pt)
JP (1) JPH0763372B2 (pt)
KR (1) KR920004050B1 (pt)
CN (1) CN86107885A (pt)
AT (1) ATE92527T1 (pt)
AU (1) AU583683B2 (pt)
CA (1) CA1285895C (pt)
CS (1) CS276453B6 (pt)
DD (1) DD252614A5 (pt)
DE (1) DE3688831T2 (pt)
DK (1) DK565186A (pt)
EG (1) EG17949A (pt)
ES (1) ES2058055T3 (pt)
FI (1) FI95929C (pt)
HU (1) HUT43112A (pt)
IE (1) IE64519B1 (pt)
IL (1) IL80754A (pt)
IN (1) IN166428B (pt)
MX (1) MX4334A (pt)
NO (1) NO176025C (pt)
NZ (1) NZ218286A (pt)
PH (2) PH25941A (pt)
PL (1) PL152882B1 (pt)
PT (1) PT83819B (pt)
TW (1) TW215457B (pt)
YU (1) YU46031B (pt)
ZA (1) ZA868601B (pt)

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CA1341074C (en) 1987-06-22 2000-08-08 Hans A. Thoma Hbv surface antigen particles, prepared by recombinant dna processes, composed of different epitopes, selected from the pre-s and s-peptides as a new vaccine
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US5011915A (en) * 1987-10-26 1991-04-30 Merck & Co., Inc. Process for purifying recombinant hepatitis antigens
US5004688A (en) * 1988-04-15 1991-04-02 Phillips Petroleum Company Purification of hepatitis proteins
IL89989A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human interleukin-2 in methylotrophic yeasts
IL89993A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of the hiv 24kda gag protein in methylotrophic yeasts
NZ228774A (en) * 1988-04-25 1991-05-28 Phillips Petroleum Co Hbv particles containing pres 2 proteins and recombinant processes for their production in yeast cells
IL89992A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human serum albumin in methylotrophic yeasts
IL90021A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Process for the production of interferon
NZ228948A (en) * 1988-05-13 1991-06-25 Phillips Petroleum Co Hbv particles containing s and pre-s 2 proteins and recombinant processes for their production in yeast cells
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US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
JPH06500470A (ja) * 1990-09-04 1994-01-20 メルク　エンド　カンパニー　インコーポレーテッド メチロトローフ酵母細胞におけるインスリン様成長因子の産生
CU22290A1 (es) * 1990-10-08 1995-01-31 Cigb Procedimiento para la obtencion de antigeno de superficie del virus de la hepatitis b de superior capacidad inmunoganica y su uso en un preparado vacunal
US5268273A (en) * 1990-12-14 1993-12-07 Phillips Petroleum Company Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same
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DE69232666T2 (de) * 1991-04-01 2003-03-20 Merck & Co., Inc. Gene, die die proteolytische aktivitaet von pichia beeinflussen und deren verwendung
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NZ253137A (en) 1992-06-25 1996-08-27 Smithkline Beecham Biolog Vaccine comprising antigen and/or antigenic composition, qs21 (quillaja saponaria molina extract) and 3 de-o-acylated monophosphoryl lipid a.
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US9566329B2 (en) 2012-04-06 2017-02-14 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Live, attenuated rubella vector to express vaccine antigens
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Also Published As

Publication number Publication date
ZA868601B (en) 1987-06-24
DK565186A (da) 1987-05-27
NO176025B (no) 1994-10-10
JPS62190085A (ja) 1987-08-20
AU6538486A (en) 1987-05-28
EP0226846A1 (en) 1987-07-01
ES2058055T3 (es) 1994-11-01
IN166428B (pt) 1990-05-05
DE3688831D1 (de) 1993-09-09
YU46031B (sh) 1992-12-21
US4895800A (en) 1990-01-23
DK565186D0 (da) 1986-11-25
NO176025C (no) 1995-01-18
NZ218286A (en) 1991-07-26
PL262598A1 (en) 1987-09-21
EG17949A (en) 1991-03-30
IL80754A0 (en) 1987-02-27
KR870005099A (ko) 1987-06-04
PT83819A (en) 1986-12-01
CA1285895C (en) 1991-07-09
KR920004050B1 (ko) 1992-05-23
NO864704D0 (no) 1986-11-25
CS276453B6 (en) 1992-06-17
FI864791A (fi) 1987-05-27
FI864791A0 (fi) 1986-11-25
TW215457B (pt) 1993-11-01
MX4334A (es) 1993-12-01
ATE92527T1 (de) 1993-08-15
FI95929C (fi) 1996-04-10
PH25539A (en) 1991-07-24
CS864186A3 (en) 1992-01-15
JPH0763372B2 (ja) 1995-07-12
EP0226846B1 (en) 1993-08-04
YU201386A (en) 1988-10-31
PH25941A (en) 1991-12-19
AU583683B2 (en) 1989-05-04
IL80754A (en) 1993-03-15
PL152882B1 (en) 1991-02-28
IE863021L (en) 1987-05-26
DE3688831T2 (de) 1993-11-25
CN86107885A (zh) 1987-09-23
HUT43112A (en) 1987-09-28
PT83819B (pt) 1988-10-14
FI95929B (fi) 1995-12-29
IE64519B1 (en) 1995-08-09

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RPI Change in the person, name or address of the patentee (searches according to art. 11 and 12 extension act)
RPV Change in the person, the name or the address of the representative (searches according to art. 11 and 12 extension act)
ASS Change of applicant or owner

Owner name: RESEARCH CORPORATION TECHNOLOGIES, INC

Effective date: 19940503

IF04 In force in the year 2004

Expiry date: 20061126