YU46031B - Postupak za proizvodnju površinskog antigena hepatitisa b iz kvasca - Google Patents

Postupak za proizvodnju površinskog antigena hepatitisa b iz kvasca

Info

Publication number
YU46031B
YU46031B YU201386A YU201386A YU46031B YU 46031 B YU46031 B YU 46031B YU 201386 A YU201386 A YU 201386A YU 201386 A YU201386 A YU 201386A YU 46031 B YU46031 B YU 46031B
Authority
YU
Yugoslavia
Prior art keywords
hepatitis
surface antigen
production
yeast
procedure
Prior art date
Application number
YU201386A
Other languages
English (en)
Other versions
YU201386A (en
Inventor
F.J. Tschopp
M.M. Harpold
J.M. Cregg
R.G. Buckholz
Original Assignee
Phillips Petroleum Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phillips Petroleum Company filed Critical Phillips Petroleum Company
Publication of YU201386A publication Critical patent/YU201386A/xx
Publication of YU46031B publication Critical patent/YU46031B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

POSTUPAK ZA PROIZVODNJU POVRŠINSKOG ANTIGENA HEPATITISA B IZ KVASCA, naznačen time, što se kultiviše soj kvasca koji je transformisan pomoću plazmida u hranljivoj podlozi koja se sastoji bar od jednog izvora ugljenika i enegije odabranog iz grupe koja se sastoji od metanola, i kataboličkog nerepresivnog izvora ugljenika, ili bar jednog kataboličkog represivnog izvora ugljenika i energije pod ulsovom da se u slučaju jednog kataboličkog represivnog izvora ugljenika i energije dobijeni proizvod podvrgava uslovima izvora ugljenika koji se iscrpljuje, gde se plazmid sastoji od DNK fragmenta, bakterijalnog plazmida DNK, gena markera kvasca koji može da se bira, i autonomne replikacione sekvence kvasca, i gde se DNK fragment sastoji od regulativnog regiona koji je sposoban da kontroliše transkripciju masengera DNK kada se postavi u položaj na 5 kraj regiona koji šifrira polipeptid; gde je regulativni region osetljiv na bar jedan od uslova odabranih iz grupa koja se sastoji od; prisustva metanola u hranljivoj podlozi sa kojim je organizam domaćin koji sadrži DNK fragment u dodiru, prisustva nekataboličkog represivnog izvora ugljenika koji se razlikuje od metanola u hranljivoj podlozi sa kojim je organizam domaćin koji sadrži DNK fragment u dodiru, i izvora ugljenika koji se iscrpljuje u hranljivoj podlozi sa kojim je organizam domaćin koji sadrži DNK fragment u dodiru posle rasta organizma domaćina na katabolički represivnom izvoru ugljenika i energije; i regiona koji šifrira polipeptid u kome region koji šifrira za površinski antigen hepatitisa B ili delove istoga. Prijava sadrži 12 zavisnih patentnih zahteva.
YU201386A 1985-11-26 1986-11-25 Postupak za proizvodnju površinskog antigena hepatitisa b iz kvasca YU46031B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/801,713 US4895800A (en) 1985-11-26 1985-11-26 Yeast production of hepatitis B surface antigen

Publications (2)

Publication Number Publication Date
YU201386A YU201386A (en) 1988-10-31
YU46031B true YU46031B (sh) 1992-12-21

Family

ID=25181867

Family Applications (1)

Application Number Title Priority Date Filing Date
YU201386A YU46031B (sh) 1985-11-26 1986-11-25 Postupak za proizvodnju površinskog antigena hepatitisa b iz kvasca

Country Status (28)

Country Link
US (1) US4895800A (sh)
EP (1) EP0226846B1 (sh)
JP (1) JPH0763372B2 (sh)
KR (1) KR920004050B1 (sh)
CN (1) CN86107885A (sh)
AT (1) ATE92527T1 (sh)
AU (1) AU583683B2 (sh)
CA (1) CA1285895C (sh)
CS (1) CS276453B6 (sh)
DD (1) DD252614A5 (sh)
DE (1) DE3688831T2 (sh)
DK (1) DK565186A (sh)
EG (1) EG17949A (sh)
ES (1) ES2058055T3 (sh)
FI (1) FI95929C (sh)
HU (1) HUT43112A (sh)
IE (1) IE64519B1 (sh)
IL (1) IL80754A (sh)
IN (1) IN166428B (sh)
MX (1) MX4334A (sh)
NO (1) NO176025C (sh)
NZ (1) NZ218286A (sh)
PH (2) PH25941A (sh)
PL (1) PL152882B1 (sh)
PT (1) PT83819B (sh)
TW (1) TW215457B (sh)
YU (1) YU46031B (sh)
ZA (1) ZA868601B (sh)

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Also Published As

Publication number Publication date
ZA868601B (en) 1987-06-24
DK565186A (da) 1987-05-27
NO176025B (no) 1994-10-10
JPS62190085A (ja) 1987-08-20
AU6538486A (en) 1987-05-28
EP0226846A1 (en) 1987-07-01
ES2058055T3 (es) 1994-11-01
IN166428B (sh) 1990-05-05
DE3688831D1 (de) 1993-09-09
US4895800A (en) 1990-01-23
DK565186D0 (da) 1986-11-25
NO176025C (no) 1995-01-18
NZ218286A (en) 1991-07-26
PL262598A1 (en) 1987-09-21
EG17949A (en) 1991-03-30
IL80754A0 (en) 1987-02-27
KR870005099A (ko) 1987-06-04
PT83819A (en) 1986-12-01
CA1285895C (en) 1991-07-09
KR920004050B1 (ko) 1992-05-23
NO864704D0 (no) 1986-11-25
CS276453B6 (en) 1992-06-17
FI864791A (fi) 1987-05-27
FI864791A0 (fi) 1986-11-25
TW215457B (sh) 1993-11-01
MX4334A (es) 1993-12-01
ATE92527T1 (de) 1993-08-15
FI95929C (fi) 1996-04-10
PH25539A (en) 1991-07-24
CS864186A3 (en) 1992-01-15
JPH0763372B2 (ja) 1995-07-12
EP0226846B1 (en) 1993-08-04
YU201386A (en) 1988-10-31
PH25941A (en) 1991-12-19
AU583683B2 (en) 1989-05-04
IL80754A (en) 1993-03-15
PL152882B1 (en) 1991-02-28
IE863021L (en) 1987-05-26
DD252614A5 (de) 1987-12-23
DE3688831T2 (de) 1993-11-25
CN86107885A (zh) 1987-09-23
HUT43112A (en) 1987-09-28
PT83819B (pt) 1988-10-14
FI95929B (fi) 1995-12-29
IE64519B1 (en) 1995-08-09

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