ES2002490A6 - Un metodo de preparar un virus recombinante - Google Patents
Un metodo de preparar un virus recombinanteInfo
- Publication number
- ES2002490A6 ES2002490A6 ES8602123A ES8602123A ES2002490A6 ES 2002490 A6 ES2002490 A6 ES 2002490A6 ES 8602123 A ES8602123 A ES 8602123A ES 8602123 A ES8602123 A ES 8602123A ES 2002490 A6 ES2002490 A6 ES 2002490A6
- Authority
- ES
- Spain
- Prior art keywords
- virus
- immunoassays
- vaccines
- recombinant
- immune deficiency
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 208000030507 AIDS Diseases 0.000 title abstract 2
- 238000003018 immunoassay Methods 0.000 title abstract 2
- 208000011580 syndromic disease Diseases 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 abstract 5
- 210000004027 cell Anatomy 0.000 abstract 3
- 239000002773 nucleotide Substances 0.000 abstract 3
- 125000003729 nucleotide group Chemical group 0.000 abstract 3
- 230000014509 gene expression Effects 0.000 abstract 2
- 208000008771 Lymphadenopathy Diseases 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 208000018555 lymphatic system disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 230000007482 viral spreading Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
UN METODO DE PREPARAR UN VIRUS RECOMBINANTE QUE DIRIGE LA EXPRESION DE UN PEPTIDO O UNA PROTEINA RELACIONADOS CON UN EPITOPE DE VIRUS ASOCIADO A LINFOADENOPATIAS/VIRUS DE LEUCEMIA DE CELULAS T HUMANAS (LAV/HTLV-III) EN UNA CELULA HOSPEDANTE INFECTADA CON EL VIRUS RECOMBINANTE, EN DONDE SE INFECTA UNA CELULA CON UN VIRUS RECOMBINANTE CUYO GENOMA COMPRENDE UNA SECUENCIA DE NUCLEOTIDOS QUE CODIFICA UN EPITOPE DE LAV/HTLV-III, O UNA PORCION ANTIGENICA DEL MISMO, EN QUE LA SECUENCIA DE NUCLEOTIDOS ESTA BAJO EL CONTROL DE UNA SEGUNDA SECUENCIA DE NUCLEOTIDOS QUE REGULA LA EXPRESION DEL GEN, Y SE PROPAGA EL VIRUS RECOMBINANTE PROPAGANDO LA CELULA INFECTADA. EL INVENTO ES PARTICULARMENTE UTIL EN RELACION CON VACUNAS E INMUNOENSAYOS PARA EL SINDROME DE INMUNODEFICIENCIA ADQUIRIDA (SIDA).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77990985A | 1985-09-25 | 1985-09-25 | |
US84298486A | 1986-03-27 | 1986-03-27 | |
US90521786A | 1986-09-09 | 1986-09-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2002490A6 true ES2002490A6 (es) | 1988-08-16 |
Family
ID=27419757
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8602123A Expired ES2002490A6 (es) | 1985-09-25 | 1986-09-24 | Un metodo de preparar un virus recombinante |
ES8801494A Expired ES2006941A6 (es) | 1985-09-25 | 1988-05-13 | Un metodo de producir un peptido o una proteina relacionados con un epitope de virus asociado a linfoadenopatiasnvirus de leucemia de celulas t humanas (lavnhtlv-iii). |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8801494A Expired ES2006941A6 (es) | 1985-09-25 | 1988-05-13 | Un metodo de producir un peptido o una proteina relacionados con un epitope de virus asociado a linfoadenopatiasnvirus de leucemia de celulas t humanas (lavnhtlv-iii). |
Country Status (22)
Country | Link |
---|---|
CN (1) | CN1020752C (es) |
AT (1) | ATA256786A (es) |
CH (1) | CH676247A5 (es) |
DE (1) | DE3690508T1 (es) |
DK (1) | DK455486A (es) |
ES (2) | ES2002490A6 (es) |
FI (1) | FI863848A (es) |
FR (1) | FR2587720A2 (es) |
GB (1) | GB2181435B (es) |
GR (1) | GR862412B (es) |
HU (1) | HU205780B (es) |
IE (1) | IE59314B1 (es) |
IL (1) | IL80073A (es) |
IT (1) | IT1195829B (es) |
MY (1) | MY103182A (es) |
NL (1) | NL8602422A (es) |
NO (1) | NO863803L (es) |
NZ (1) | NZ217645A (es) |
PT (1) | PT83434B (es) |
SE (4) | SE8604007L (es) |
WO (1) | WO1987002038A1 (es) |
YU (1) | YU46753B (es) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986006099A1 (en) * | 1985-04-08 | 1986-10-23 | Genetic Systems Corporation | EXPRESSION AND DIAGNOSTIC USE OF gag ENCODED PEPTIDES WHICH ARE IMMUNOLOGICALLY REACTIVE WITH ANTIBODIES TO LAV |
US4734362A (en) * | 1986-02-03 | 1988-03-29 | Cambridge Bioscience Corporation | Process for purifying recombinant proteins, and products thereof |
US4925784A (en) * | 1986-04-04 | 1990-05-15 | Hoffmann-La Roche Inc. | Expression and purification of an HTLV-III gag/env gene protein |
US4983387A (en) * | 1986-05-19 | 1991-01-08 | Viral Technologies Inc. | HIV related peptides, immunogenic antigens, and use therefor as subunit vaccine for AIDS virus |
EP0260714B1 (en) * | 1986-09-19 | 1994-06-29 | Oncogen Limited Partnership | The use of activated t-lymphocytes for preparing a pharmaceutical composition for the treatment of AIDS |
IL84154A0 (en) * | 1986-10-16 | 1988-03-31 | Microgenesys Inc | Polypeptides derived from the envelope gene of human immunodeficiency virus in recombinant baculovirus infected insect cells and vaccines against acquired immune deficiency syndrome containing the same |
JPS63258575A (ja) * | 1986-12-15 | 1988-10-26 | レプリゲン コーポレーション | 昆虫細胞中でつくられる組換えhivエンベロープタンパク |
FR2610632B1 (fr) * | 1987-02-11 | 1990-12-21 | Pasteur Institut | Peptides caracteristiques des retrovirus d'immunodeficience humaine (virus hiv) leurs applications au diagnostic des infections dues a certains de ces virus et, le cas echeant, a la vaccination contre le sida |
WO1988005440A1 (fr) * | 1987-01-16 | 1988-07-28 | Institut Pasteur | Peptides ayant des proprietes immunologiques 2-hiv-2 |
US5681713A (en) * | 1987-05-08 | 1997-10-28 | Smithkline Beecham Corporation | Expression of heterologous proteins in Drosophila cells |
GB8714802D0 (en) * | 1987-06-24 | 1987-07-29 | Proteus Biotech Ltd | Synthetic polypeptides |
DE10399032I1 (de) * | 1987-08-28 | 2004-01-29 | Health Research Inc | Rekombinante Viren. |
FR2620030B1 (fr) * | 1987-09-07 | 1990-03-23 | Transgene Sa | Vecteur d'expression des proteines du virus hiv-2, un agent causal du sida, culture cellulaire infectee ou transformee par ce vecteur, proteines obtenues, vaccin et anticorps obtenus |
IL89118A0 (en) * | 1988-02-03 | 1989-08-15 | Microgenesys Inc | Vaccine containing polypeptides derived from the envelope gene of human immunodeficiency virus type 1 |
US5763160A (en) * | 1988-02-12 | 1998-06-09 | United Biomedical, Inc. | Synthetic peptides and process of using same for the detection of antibodies to human immunodeficiency virus (HIV) gp120 envelope protein, diagnosis of AIDS and pre-AIDS conditions and as vaccines |
DE68917520T2 (de) * | 1988-05-06 | 1995-01-05 | Ferropas Ag | Verfahren und Systeme zur Herstellung von HIV-Antigenen. |
US5043262A (en) * | 1988-05-12 | 1991-08-27 | Dana Farber Cancer Institute | Protein, sequences containing the VPU gene therefore, vectors, methods of preparation and use |
AP129A (en) * | 1988-06-03 | 1991-04-17 | Smithkline Biologicals S A | Expression of retrovirus gag protein eukaryotic cells |
AU3775789A (en) * | 1988-06-10 | 1990-01-05 | Applied Biotechnology, Inc. | A method of evaluating recombinant vaccines against immunodeficiency virus |
US5614404A (en) * | 1988-06-10 | 1997-03-25 | Theriod Biologics, Incorporated | Self-assembled, defective, non-self-propagating lentivirus particles |
US5747324A (en) * | 1988-06-10 | 1998-05-05 | Therion Biologics Corporation | Self-assembled, defective, non-self-propagating lentivirus particles |
US5631154A (en) * | 1988-06-10 | 1997-05-20 | Therion Biologics, Incorporated | Self assembled, defective, non-self-propagating lentivirus particles |
US5665577A (en) * | 1989-02-06 | 1997-09-09 | Dana-Farber Cancer Institute | Vectors containing HIV packaging sequences, packaging defective HIV vectors, and uses thereof |
ATE160377T1 (de) * | 1989-04-18 | 1997-12-15 | Applied Biotechnology Inc | Erzeugung von hybrid-genen und proteinen durch rekombination mittels viren |
EP1288304A3 (en) * | 1989-06-01 | 2006-04-05 | Applied Biotechnology, Inc. | Self-assembled, defective, non-self-propagating viral particles |
GB8923123D0 (en) | 1989-10-13 | 1989-11-29 | Connaught Lab | A vaccine for human immunodeficiency virus |
US5981276A (en) * | 1990-06-20 | 1999-11-09 | Dana-Farber Cancer Institute | Vectors containing HIV packaging sequences, packaging defective HIV vectors, and uses thereof |
FR2676068B1 (fr) * | 1991-05-02 | 1994-11-04 | Pasteur Institut | Souches recombinantes immunogenes de b. anthracis - compositions immunogenes les contenant. |
US5840312A (en) * | 1991-05-02 | 1998-11-24 | Institut Pasteur | Recombinant Bacillus anthracis strains unable to produce the lethal factor protein or edema factor protein |
WO1993009238A1 (en) * | 1991-11-08 | 1993-05-13 | The Upjohn Company | Feline leukemia virus vaccines |
DE4405810A1 (de) | 1994-02-23 | 1995-08-24 | Behringwerke Ag | Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung |
EP0888128A2 (en) | 1995-02-10 | 1999-01-07 | The Worcester Foundation For Biomedical Research | Delivery of exogenous compounds |
US6013506A (en) * | 1995-06-05 | 2000-01-11 | Wardley; Richard C. | Feline leukemia virus vaccines |
ES2143570T3 (es) * | 1995-09-06 | 2000-05-16 | Schablonentechnik Kufstein Ag | Procedimiento para la fabricacion de una plantilla de serigrafia. |
US5741492A (en) * | 1996-01-23 | 1998-04-21 | St. Jude Children's Research Hospital | Preparation and use of viral vectors for mixed envelope protein vaccines against human immunodeficiency viruses |
US6723558B1 (en) | 1996-01-23 | 2004-04-20 | St. Jude Children's Research Hospital | Preparation and use of viral vectors for mixed envelope protein vaccines against human immunodeficiency viruses |
US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
EP1458360B1 (en) | 2001-12-19 | 2011-05-11 | Novartis AG | Pulmonary delivery of aminoglycosides |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE78293T1 (de) * | 1983-05-27 | 1992-08-15 | Texas A & M Univ Sys | Verfahren zur herstellung eines rekombinanten baculovirus-expressionsvektors. |
US4662514A (en) * | 1983-11-01 | 1987-05-05 | Charleswater Products, Inc. | Electrically conductive polymeric tubes for static sensitive electronic devices |
IL76082A (en) * | 1984-08-22 | 1991-07-18 | Us Health | Molecular clones of the genome of htlv-iii and a process for the preparation thereof |
US9328391B1 (en) * | 1984-08-22 | 2016-05-03 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Cloning and expression of HIV-1 DNA |
GB8501473D0 (en) * | 1985-01-21 | 1985-02-20 | Pasteur Institut | Cloned dna sequences |
DE3588248T2 (de) * | 1984-10-18 | 2004-07-01 | Institut Pasteur | LAV-Antigene und -Peptide |
CA1341482C (en) * | 1984-10-31 | 2005-05-10 | Paul A. Luciw | Process for preparing fragments of aids-associated retroviruses |
AU600658B2 (en) * | 1984-12-24 | 1990-08-23 | Genentech Inc. | Molecularly cloned acquired immunodeficiency syndrome polypeptides and their methods of use |
US4774175A (en) * | 1985-03-01 | 1988-09-27 | Centocor, Inc. | Immunochemical methods for the detection of antibody against HTLV-III |
FI861626A (fi) * | 1985-04-19 | 1986-10-20 | Hoffmann La Roche | Foervaervat immunbristsyndrom (aids) -relaterat viralt rekombinant hoeljeprotein samt ett testfoerfarande foer aids. |
FR2586427B1 (fr) * | 1985-08-20 | 1988-12-09 | Pasteur Institut | Sequences de nucleotides et de polypeptides issus du virus visna et leur application a des essais de diagnostic et a la production de compositions immunogenes |
-
1986
- 1986-09-22 NZ NZ217645A patent/NZ217645A/xx unknown
- 1986-09-22 GR GR862412A patent/GR862412B/el unknown
- 1986-09-23 IE IE252586A patent/IE59314B1/en not_active IP Right Cessation
- 1986-09-23 SE SE8604007A patent/SE8604007L/xx not_active Application Discontinuation
- 1986-09-24 HU HU864072A patent/HU205780B/hu not_active IP Right Cessation
- 1986-09-24 ES ES8602123A patent/ES2002490A6/es not_active Expired
- 1986-09-24 DK DK455486A patent/DK455486A/da not_active Application Discontinuation
- 1986-09-24 IT IT67730/86A patent/IT1195829B/it active
- 1986-09-24 CH CH3821/86A patent/CH676247A5/fr not_active IP Right Cessation
- 1986-09-24 NO NO863803A patent/NO863803L/no unknown
- 1986-09-24 GB GB8622987A patent/GB2181435B/en not_active Expired - Fee Related
- 1986-09-24 FI FI863848A patent/FI863848A/fi not_active IP Right Cessation
- 1986-09-25 YU YU165486A patent/YU46753B/sh unknown
- 1986-09-25 CN CN86106632A patent/CN1020752C/zh not_active Expired - Fee Related
- 1986-09-25 AT AT0256786A patent/ATA256786A/de unknown
- 1986-09-25 DE DE19863690508 patent/DE3690508T1/de not_active Withdrawn
- 1986-09-25 FR FR8613414A patent/FR2587720A2/fr active Granted
- 1986-09-25 NL NL8602422A patent/NL8602422A/nl not_active Application Discontinuation
- 1986-09-25 WO PCT/US1986/002002 patent/WO1987002038A1/en active Application Filing
- 1986-09-25 PT PT83434A patent/PT83434B/pt not_active IP Right Cessation
- 1986-12-31 IL IL8007386A patent/IL80073A/en not_active IP Right Cessation
-
1987
- 1987-09-29 MY MYPI87002188A patent/MY103182A/en unknown
-
1988
- 1988-05-13 ES ES8801494A patent/ES2006941A6/es not_active Expired
-
1991
- 1991-10-14 SE SE9102976A patent/SE9102976L/xx not_active Application Discontinuation
- 1991-10-14 SE SE9102975A patent/SE9102975L/xx not_active Application Discontinuation
- 1991-10-14 SE SE9102974A patent/SE9102974L/xx not_active Application Discontinuation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2002490A6 (es) | Un metodo de preparar un virus recombinante | |
ATE325882T1 (de) | Polypeptide, die mit alfalfamosaikviralen oder ilarviralen kapsiden fusioniert sind | |
DE10399037I2 (de) | Rekombinante Virusproteine begleitet von lymphadenopathischem Sydrom und/oder "Acquired Immune Deficiency Syndrome" (AIDS). | |
FI935808A (fi) | Hepatit-C-virus (HCV) polypeptider | |
ES8105388A1 (es) | Un metodo para mantener, replicar y expresar por lo menos una porcion del genoma de un virus n.p. | |
EP0608261A4 (en) | COMPOSITION OF AN IMMUNREACTIVE HEPATITIS C VIRUS POLYPEPTIDE. | |
ES8500322A1 (es) | Un metodo de modificar un virus para conferirle una nueva funcion biologica. | |
AU8223187A (en) | T cell epitopes of the hepatitis b virus nucleocapsid protein | |
ATE496630T1 (de) | Immunologische zusammensetzung und impfstoffe, die einen auf n-formyl-methionyl peptide bestehenden adjuvans enthalten | |
ES8500996A1 (es) | Meotod de producir un polipeptido. | |
EA200000528A1 (ru) | Способ получения вакцин для предупреждения патогенных эффектов, связанных с ретровирусной инфекцией | |
BR9202024A (pt) | Virus de apivox recombinante,cultura de celulas eucariotica infectadas por um virus de avipox,vacina,sequencia de transferencia e plasmideo | |
KR860004146A (ko) | 경구용 백신의 제조방법 | |
ES8706208A1 (es) | Un metodo para preparar proteinas que son inmunologicamente reactivas con anticuerpos para virus asociados con linfadenopatia | |
ES8706824A1 (es) | Un metodo para preparar proteinas que son inmunologicamente reactivas con anticuerpos para virus asociados con linfadenopatia. | |
DE3585578D1 (de) | Hepatitisoberflaechenantigenpartikelvakzin. | |
DK457687A (da) | Antigenisk aktive proteiner og peptider, og vacciner mod virus for felin peritonitis (fipv) med indhold af saadanne proteiner eller peptider | |
EP0236977A3 (en) | Bovine virus diarrhea and hog cholera vaccines | |
EP0327180A3 (en) | Vaccine containing polypeptides derived from the envelope gene of human immunodeficiency virus type 1 | |
EP0257721A3 (en) | Vaccine | |
FI870501A (fi) | Menetelmä melanoomaan liittyvän p97-antigeenin antigeenisen sukulaispeptidin tai -proteiinin valmistamiseksi, sekä siinä käyttökelpoiset yhdistelmävirukset, yhdistelmävektorit ja isäntäsolut | |
ES8801959A1 (es) | Un procedimiento para ensayos de sangre humana respecto de la presencia de anticuerpos frente al agente etiologico viral de sida | |
DK589586A (da) | Ekspression og diagnostisk anvendelse af gag-kodede peptider, der er immunologisk reaktive med antistoffer til lav. | |
SU1380209A1 (ru) | РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК PUR 291-HAV 22, КОДИРУЮЩАЯ СИНТЕЗ ГИБРИДНОГО ПОЛИПЕПТИДА АНТИГЕННЫХ ДЕТЕРМИНАНТ ВИРУСА ГЕПАТИТА А С β -ГАЛАКТОЗИДАЗОЙ | |
SU1533329A1 (ru) | Штамм гибридных культивируемых клеток животных mus musculus, используемый для получения моноклональных антител к белку е оболочки вирусов комплекса клещевого энцефалита |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
SA6 | Expiration date (snapshot 920101) |
Free format text: 2006-09-24 |
|
FD1A | Patent lapsed |
Effective date: 20000601 |