ES8500996A1 - Meotod de producir un polipeptido. - Google Patents

Meotod de producir un polipeptido.

Info

Publication number
ES8500996A1
ES8500996A1 ES520877A ES520877A ES8500996A1 ES 8500996 A1 ES8500996 A1 ES 8500996A1 ES 520877 A ES520877 A ES 520877A ES 520877 A ES520877 A ES 520877A ES 8500996 A1 ES8500996 A1 ES 8500996A1
Authority
ES
Spain
Prior art keywords
novel dna
host
human immune
immune interferon
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES520877A
Other languages
English (en)
Other versions
ES520877A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES520877A0 publication Critical patent/ES520877A0/es
Publication of ES8500996A1 publication Critical patent/ES8500996A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

METODO DE PRODUCIR UN POLIPEPTIDO.CONSISTE EN CULTIVAR UN HOSPEDANTE TRANSFORMADO CON UN ADN QUE CONTIENE UNA SECUENCIA DE BASES DE FORMULA (II); ACUMULAR EL POLIPEPTIDO DE FORMULA (I) EN EL CALDO DE CULTIVO; Y RECUPERAR EL MISMO SOMETIENDOLO A CONGELACION, DESCONGELACION Y TRATAMIENTO DE LISOZIMA EN PRESENCIA DE ETILENDIAMINA.TIENE APLICACION PARA OBTENCION DE PRODUCTOS DE INTERFERON.
ES520877A 1982-03-24 1983-03-23 Meotod de producir un polipeptido. Expired ES8500996A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8200080 1982-03-24
US39738482A 1982-07-12 1982-07-12

Publications (2)

Publication Number Publication Date
ES520877A0 ES520877A0 (es) 1984-11-01
ES8500996A1 true ES8500996A1 (es) 1984-11-01

Family

ID=26422985

Family Applications (1)

Application Number Title Priority Date Filing Date
ES520877A Expired ES8500996A1 (es) 1982-03-24 1983-03-23 Meotod de producir un polipeptido.

Country Status (8)

Country Link
EP (1) EP0089676A3 (es)
AU (1) AU1274483A (es)
ES (1) ES8500996A1 (es)
FI (1) FI830984L (es)
GR (1) GR78493B (es)
IL (1) IL68100A0 (es)
NO (1) NO831041L (es)
PH (1) PH20744A (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58110548A (ja) * 1981-12-24 1983-07-01 Asahi Chem Ind Co Ltd 新規な生理活性ペプチド
EP0088540A3 (en) * 1982-02-22 1984-10-17 Biogen, Inc. Dna sequences, recombinant dna molecules and processes for producing human immune interferon-like polypeptides
JPH0787797B2 (ja) * 1982-05-20 1995-09-27 サントリー株式会社 ヒト・ガンマ・インタ−フエロン様ポリペプチドの製造法
US4582800A (en) * 1982-07-12 1986-04-15 Hoffmann-La Roche Inc. Novel vectors and method for controlling interferon expression
AU571460B2 (en) * 1982-09-27 1988-04-21 Cancer Institute Of Japanese Foundation For Cancer Research Alpha interferon dna, recombinant plasmid, engineered organism and alpha interferon polypeptide
WO1984002129A1 (en) * 1982-11-22 1984-06-07 Takeda Chemical Industries Ltd Human immune interferon protein and process for its preparation
JPH0740925B2 (ja) * 1983-03-14 1995-05-10 協和醗酵工業株式会社 新規ヒトインタ−フエロン−γポリペプチド
JPS59169494A (ja) * 1983-03-17 1984-09-25 Takeda Chem Ind Ltd 新規組み換えｄｎａおよびその用途
ZA846554B (en) * 1983-09-20 1985-04-24 Hoffmann La Roche Immune interferon and method for its purification
JPH0788398B2 (ja) * 1983-10-17 1995-09-27 サントリー株式会社 新規生理活性ポリペプチドおよびその製造法
FR2556365B1 (fr) * 1983-12-09 1987-07-31 Transgene Sa Vecteurs de clonage et d'expression de l'interferon-g, bacteries transformees et procede de preparation de l'interferon-g
MX9203641A (es) * 1983-12-16 1992-07-01 Genentech Inc Interferones gamma recombinantes que poseen estabilidad mejorada y metodos biotecnologicos para su obtencion.
US4855238A (en) 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
US4935370A (en) * 1983-12-23 1990-06-19 Pfizer Inc. Expression plasmids for improved production of heterologous protein in bacteria
DE3484926D1 (de) * 1983-12-23 1991-09-19 Pfizer Expressionsplasmide fuer die herstellung eines heterologen proteins in bakterien.
US4758656A (en) * 1983-12-26 1988-07-19 Kyowa Hakko Kogyo Co., Ltd. Novel human interferon-gamma polypeptide derivative
EP0158198A1 (en) * 1984-03-29 1985-10-16 Takeda Chemical Industries, Ltd. DNA and use thereof
DE3414831A1 (de) * 1984-04-19 1985-10-31 Hoechst Ag, 6230 Frankfurt Herstellung von polypeptiden mit human-gammainterferon-aktivitaet
IL75302A0 (en) * 1984-06-06 1985-09-29 Takeda Chemical Industries Ltd Novel polypeptide and production thereof
GB2164650A (en) * 1984-09-25 1986-03-26 Fujisawa Pharmaceutical Co Process for production of y-interferon
US4935352A (en) * 1985-10-21 1990-06-19 Takeda Chemical Industries, Ltd. Expression vector for animal cell line and use thereof
CZ20021836A3 (cs) 1999-11-12 2002-08-14 Maxygen Holdings Ltd Konjugáty interferonu gama
US7230081B1 (en) 1999-11-12 2007-06-12 Maxygen Holdings, Ltd. Interferon gamma conjugates
US7038015B2 (en) 2001-04-06 2006-05-02 Maxygen Holdings, Ltd. Interferon gamma polypeptide variants
US6958388B2 (en) 2001-04-06 2005-10-25 Maxygen, Aps Interferon gamma polypeptide variants
CA2491178A1 (en) 2002-07-03 2004-01-15 Maxygen Holdings Ltd. Full-length interferon gamma polypeptide variants
CN101124243A (zh) 2004-12-23 2008-02-13 莫尔梅德股份有限公司 缀合产物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU561343B2 (en) * 1981-10-19 1987-05-07 Genentech Inc. Human immune interferon by recombinant dna
JPS58110548A (ja) * 1981-12-24 1983-07-01 Asahi Chem Ind Co Ltd 新規な生理活性ペプチド
EP0088540A3 (en) * 1982-02-22 1984-10-17 Biogen, Inc. Dna sequences, recombinant dna molecules and processes for producing human immune interferon-like polypeptides
JPH0787797B2 (ja) * 1982-05-20 1995-09-27 サントリー株式会社 ヒト・ガンマ・インタ−フエロン様ポリペプチドの製造法
US4582800A (en) * 1982-07-12 1986-04-15 Hoffmann-La Roche Inc. Novel vectors and method for controlling interferon expression

Also Published As

Publication number Publication date
PH20744A (en) 1987-04-02
NO831041L (no) 1983-09-26
EP0089676A3 (en) 1984-09-19
GR78493B (es) 1984-09-27
EP0089676A2 (en) 1983-09-28
ES520877A0 (es) 1984-11-01
FI830984L (fi) 1983-09-25
FI830984A0 (fi) 1983-03-23
AU1274483A (en) 1983-09-29
IL68100A0 (en) 1983-06-15

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