NO176025C - DNA-fragment, plasmid, kultur og fremgangsmåte til fremstilling av et hepatitt-B-overflateantigen - Google Patents

DNA-fragment, plasmid, kultur og fremgangsmåte til fremstilling av et hepatitt-B-overflateantigen

Info

Publication number
NO176025C
NO176025C NO864704A NO864704A NO176025C NO 176025 C NO176025 C NO 176025C NO 864704 A NO864704 A NO 864704A NO 864704 A NO864704 A NO 864704A NO 176025 C NO176025 C NO 176025C
Authority
NO
Norway
Prior art keywords
hepatitis
surface antigen
plasmid
culture
producing
Prior art date
Application number
NO864704A
Other languages
English (en)
Other versions
NO176025B (no
NO864704D0 (no
Inventor
Juerg Friedrich Tschopp
James Michael Cregg
Michael Miller Harpold
Richard Gordon Buckholz
Original Assignee
Res Corp Technologies Inc
Phillips Petroleum Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Corp Technologies Inc, Phillips Petroleum Co filed Critical Res Corp Technologies Inc
Publication of NO864704D0 publication Critical patent/NO864704D0/no
Publication of NO176025B publication Critical patent/NO176025B/no
Publication of NO176025C publication Critical patent/NO176025C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO864704A 1985-11-26 1986-11-25 DNA-fragment, plasmid, kultur og fremgangsmåte til fremstilling av et hepatitt-B-overflateantigen NO176025C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/801,713 US4895800A (en) 1985-11-26 1985-11-26 Yeast production of hepatitis B surface antigen

Publications (3)

Publication Number Publication Date
NO864704D0 NO864704D0 (no) 1986-11-25
NO176025B NO176025B (no) 1994-10-10
NO176025C true NO176025C (no) 1995-01-18

Family

ID=25181867

Family Applications (1)

Application Number Title Priority Date Filing Date
NO864704A NO176025C (no) 1985-11-26 1986-11-25 DNA-fragment, plasmid, kultur og fremgangsmåte til fremstilling av et hepatitt-B-overflateantigen

Country Status (28)

Country Link
US (1) US4895800A (no)
EP (1) EP0226846B1 (no)
JP (1) JPH0763372B2 (no)
KR (1) KR920004050B1 (no)
CN (1) CN86107885A (no)
AT (1) ATE92527T1 (no)
AU (1) AU583683B2 (no)
CA (1) CA1285895C (no)
CS (1) CS276453B6 (no)
DD (1) DD252614A5 (no)
DE (1) DE3688831T2 (no)
DK (1) DK565186A (no)
EG (1) EG17949A (no)
ES (1) ES2058055T3 (no)
FI (1) FI95929C (no)
HU (1) HUT43112A (no)
IE (1) IE64519B1 (no)
IL (1) IL80754A (no)
IN (1) IN166428B (no)
MX (1) MX4334A (no)
NO (1) NO176025C (no)
NZ (1) NZ218286A (no)
PH (2) PH25941A (no)
PL (1) PL152882B1 (no)
PT (1) PT83819B (no)
TW (1) TW215457B (no)
YU (1) YU46031B (no)
ZA (1) ZA868601B (no)

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US5026828A (en) * 1987-02-27 1991-06-25 Merck & Co., Inc. Method of purifying recombinant pres-1/S-2/S/S hepatitis B antigen from yeast
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ES2043808T3 (es) * 1987-03-09 1994-01-01 Merck & Co Inc Purificacion de antigeno superficial de hepatitis b recombinante.
CA1341074C (en) 1987-06-22 2000-08-08 Hans A. Thoma Hbv surface antigen particles, prepared by recombinant dna processes, composed of different epitopes, selected from the pre-s and s-peptides as a new vaccine
EP0314240A3 (en) * 1987-10-26 1990-03-28 Merck & Co. Inc. Process for purifying recombinant hepatitis antigens
US5011915A (en) * 1987-10-26 1991-04-30 Merck & Co., Inc. Process for purifying recombinant hepatitis antigens
US5004688A (en) * 1988-04-15 1991-04-02 Phillips Petroleum Company Purification of hepatitis proteins
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IL89993A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of the hiv 24kda gag protein in methylotrophic yeasts
NZ228774A (en) * 1988-04-25 1991-05-28 Phillips Petroleum Co Hbv particles containing pres 2 proteins and recombinant processes for their production in yeast cells
IL89992A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human serum albumin in methylotrophic yeasts
IL90021A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Process for the production of interferon
NZ228948A (en) * 1988-05-13 1991-06-25 Phillips Petroleum Co Hbv particles containing s and pre-s 2 proteins and recombinant processes for their production in yeast cells
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US6197548B1 (en) 1990-04-02 2001-03-06 Medeva Pharma Limited Transformed Pichia expressing the pertactin antigen
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
JPH06500470A (ja) * 1990-09-04 1994-01-20 メルク　エンド　カンパニー　インコーポレーテッド メチロトローフ酵母細胞におけるインスリン様成長因子の産生
CU22290A1 (es) * 1990-10-08 1995-01-31 Cigb Procedimiento para la obtencion de antigeno de superficie del virus de la hepatitis b de superior capacidad inmunoganica y su uso en un preparado vacunal
US5268273A (en) * 1990-12-14 1993-12-07 Phillips Petroleum Company Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same
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CA2063890C (en) * 1991-03-27 2007-03-13 Masami Miura Mutant aox2 promoter, microorganism carrying same, method of preparation thereof and production of heterologous protein using such microorganism
DE69232666T2 (de) * 1991-04-01 2003-03-20 Merck & Co., Inc. Gene, die die proteolytische aktivitaet von pichia beeinflussen und deren verwendung
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UA40596C2 (uk) 1992-05-23 2001-08-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини та спосіб її одержання
NZ253137A (en) 1992-06-25 1996-08-27 Smithkline Beecham Biolog Vaccine comprising antigen and/or antigenic composition, qs21 (quillaja saponaria molina extract) and 3 de-o-acylated monophosphoryl lipid a.
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US5955349A (en) * 1996-08-26 1999-09-21 Zymogenetics, Inc. Compositions and methods for producing heterologous polypeptides in Pichia methanolica
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UA79735C2 (uk) * 2000-08-10 2007-07-25 Глаксосмітклайн Байолоджікалз С.А. Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах
US7118901B2 (en) * 2002-12-18 2006-10-10 Roche Diagnostics Operations, Inc. Recombinant bovine pancreatic desoxyribonuclease I with high specific activity
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ES2337684T3 (es) * 2003-12-05 2010-04-28 F. Hoffmann-La Roche Ag Carboxipeptidasa b recombinante y su purificacion.
MY146082A (en) * 2005-09-14 2012-06-29 Sanofi Aventis Deutschland Cleavage of precursors of insulins by a variant of trypsin
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Also Published As

Publication number Publication date
ZA868601B (en) 1987-06-24
DK565186A (da) 1987-05-27
NO176025B (no) 1994-10-10
JPS62190085A (ja) 1987-08-20
AU6538486A (en) 1987-05-28
EP0226846A1 (en) 1987-07-01
ES2058055T3 (es) 1994-11-01
IN166428B (no) 1990-05-05
DE3688831D1 (de) 1993-09-09
YU46031B (sh) 1992-12-21
US4895800A (en) 1990-01-23
DK565186D0 (da) 1986-11-25
NZ218286A (en) 1991-07-26
PL262598A1 (en) 1987-09-21
EG17949A (en) 1991-03-30
IL80754A0 (en) 1987-02-27
KR870005099A (ko) 1987-06-04
PT83819A (en) 1986-12-01
CA1285895C (en) 1991-07-09
KR920004050B1 (ko) 1992-05-23
NO864704D0 (no) 1986-11-25
CS276453B6 (en) 1992-06-17
FI864791A (fi) 1987-05-27
FI864791A0 (fi) 1986-11-25
TW215457B (no) 1993-11-01
MX4334A (es) 1993-12-01
ATE92527T1 (de) 1993-08-15
FI95929C (fi) 1996-04-10
PH25539A (en) 1991-07-24
CS864186A3 (en) 1992-01-15
JPH0763372B2 (ja) 1995-07-12
EP0226846B1 (en) 1993-08-04
YU201386A (en) 1988-10-31
PH25941A (en) 1991-12-19
AU583683B2 (en) 1989-05-04
IL80754A (en) 1993-03-15
PL152882B1 (en) 1991-02-28
IE863021L (en) 1987-05-26
DD252614A5 (de) 1987-12-23
DE3688831T2 (de) 1993-11-25
CN86107885A (zh) 1987-09-23
HUT43112A (en) 1987-09-28
PT83819B (pt) 1988-10-14
FI95929B (fi) 1995-12-29
IE64519B1 (en) 1995-08-09

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