FI864791A0 - Hepatitis B pinta-antigeenin tuotanto hiivassa - Google Patents

Hepatitis B pinta-antigeenin tuotanto hiivassa

Info

Publication number
FI864791A0
FI864791A0 FI864791A FI864791A FI864791A0 FI 864791 A0 FI864791 A0 FI 864791A0 FI 864791 A FI864791 A FI 864791A FI 864791 A FI864791 A FI 864791A FI 864791 A0 FI864791 A0 FI 864791A0
Authority
FI
Finland
Prior art keywords
hepatitis
surface antigen
yeast
regulatory regions
antigen production
Prior art date
Application number
FI864791A
Other languages
English (en)
Swedish (sv)
Other versions
FI95929B (fi
FI864791A (fi
FI95929C (fi
Inventor
Juerg Friedrich Tschopp
Michael Miller Harpold
James Michael Cregg
Richard Gordon Buckholz
Original Assignee
Phillips Petroleum Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phillips Petroleum Co filed Critical Phillips Petroleum Co
Publication of FI864791A0 publication Critical patent/FI864791A0/fi
Publication of FI864791A publication Critical patent/FI864791A/fi
Publication of FI95929B publication Critical patent/FI95929B/fi
Application granted granted Critical
Publication of FI95929C publication Critical patent/FI95929C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
FI864791A 1985-11-26 1986-11-25 Hepatitis B pinta-antigeenin tuotanto hiivassa FI95929C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80171385 1985-11-26
US06/801,713 US4895800A (en) 1985-11-26 1985-11-26 Yeast production of hepatitis B surface antigen

Publications (4)

Publication Number Publication Date
FI864791A0 true FI864791A0 (fi) 1986-11-25
FI864791A FI864791A (fi) 1987-05-27
FI95929B FI95929B (fi) 1995-12-29
FI95929C FI95929C (fi) 1996-04-10

Family

ID=25181867

Family Applications (1)

Application Number Title Priority Date Filing Date
FI864791A FI95929C (fi) 1985-11-26 1986-11-25 Hepatitis B pinta-antigeenin tuotanto hiivassa

Country Status (28)

Country Link
US (1) US4895800A (fi)
EP (1) EP0226846B1 (fi)
JP (1) JPH0763372B2 (fi)
KR (1) KR920004050B1 (fi)
CN (1) CN86107885A (fi)
AT (1) ATE92527T1 (fi)
AU (1) AU583683B2 (fi)
CA (1) CA1285895C (fi)
CS (1) CS276453B6 (fi)
DD (1) DD252614A5 (fi)
DE (1) DE3688831T2 (fi)
DK (1) DK565186A (fi)
EG (1) EG17949A (fi)
ES (1) ES2058055T3 (fi)
FI (1) FI95929C (fi)
HU (1) HUT43112A (fi)
IE (1) IE64519B1 (fi)
IL (1) IL80754A (fi)
IN (1) IN166428B (fi)
MX (1) MX4334A (fi)
NO (1) NO176025C (fi)
NZ (1) NZ218286A (fi)
PH (2) PH25941A (fi)
PL (1) PL152882B1 (fi)
PT (1) PT83819B (fi)
TW (1) TW215457B (fi)
YU (1) YU46031B (fi)
ZA (1) ZA868601B (fi)

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US4683293A (en) * 1986-10-20 1987-07-28 Phillips Petroleum Company Purification of pichia produced lipophilic proteins
ATE91304T1 (de) * 1987-02-27 1993-07-15 Merck & Co Inc Verfahren zur herstellung des pres 1/s2/shepatitis-b-antigens aus hefe.
US5026828A (en) * 1987-02-27 1991-06-25 Merck & Co., Inc. Method of purifying recombinant pres-1/S-2/S/S hepatitis B antigen from yeast
ATE93891T1 (de) * 1987-03-09 1993-09-15 Merck & Co Inc Reinigung von rekombiniertem hepatitis-boberfl|chen-antigen.
ES2167304T3 (es) * 1987-06-22 2002-05-16 Medeva Holdings Bv Peptido que contiene el antigeno de superficie de la hepatitis b.
US5011915A (en) * 1987-10-26 1991-04-30 Merck & Co., Inc. Process for purifying recombinant hepatitis antigens
EP0314240A3 (en) * 1987-10-26 1990-03-28 Merck & Co. Inc. Process for purifying recombinant hepatitis antigens
US5004688A (en) * 1988-04-15 1991-04-02 Phillips Petroleum Company Purification of hepatitis proteins
IL89992A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human serum albumin in methylotrophic yeasts
NZ228774A (en) * 1988-04-25 1991-05-28 Phillips Petroleum Co Hbv particles containing pres 2 proteins and recombinant processes for their production in yeast cells
IL89993A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of the hiv 24kda gag protein in methylotrophic yeasts
IL89989A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human interleukin-2 in methylotrophic yeasts
IL90021A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Process for the production of interferon
IL90161A0 (en) * 1988-05-13 1989-12-15 Phillips Petroleum Co Expression of hepatitis b s and pres2 proteins in methylotrophic yeasts
JPH04501662A (ja) * 1988-09-26 1992-03-26 ザ・サルク・インスティチュート・バイオテクノロジー／インダストリアル・アソシエイツ・インコーポレーテッド 混合給送組換え酵母発酵
DD297841A5 (de) * 1989-02-13 1992-01-23 The Salk Institute Biotechnology/Industrial Associates,Us Herstellung von superoxiddismutase in pichia pastoris hefezellen
US6197548B1 (en) 1990-04-02 2001-03-06 Medeva Pharma Limited Transformed Pichia expressing the pertactin antigen
CA2090969C (en) * 1990-09-04 2001-08-21 Russell Arthur Brierley Production of insulin-like growth factor-1 in methylotrophic yeast cells
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
CU22290A1 (es) * 1990-10-08 1995-01-31 Cigb Procedimiento para la obtencion de antigeno de superficie del virus de la hepatitis b de superior capacidad inmunoganica y su uso en un preparado vacunal
US5268273A (en) * 1990-12-14 1993-12-07 Phillips Petroleum Company Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same
EP0491077A1 (en) * 1990-12-19 1992-06-24 Medeva Holdings B.V. A composition used as a therapeutic agent against chronic viral hepatic diseases
WO1992013951A1 (en) * 1991-02-04 1992-08-20 The Salk Institute Biotechnology/Industrial Associates, Inc. Production of human serum albumin in methylotrophic yeast cells
CA2063890C (en) * 1991-03-27 2007-03-13 Masami Miura Mutant aox2 promoter, microorganism carrying same, method of preparation thereof and production of heterologous protein using such microorganism
WO1992017595A1 (en) * 1991-04-01 1992-10-15 The Salk Institute Biotechnology/Industrial Associates, Inc. Genes which influence pichia proteolytic activity, and uses therefor
CA2058820C (en) * 1991-04-25 2003-07-15 Kotikanyad Sreekrishna Expression cassettes and vectors for the secretion of human serum albumin in pichia pastoris cells
US5330901A (en) * 1991-04-26 1994-07-19 Research Corporation Technologies, Inc. Expression of human serum albumin in Pichia pastoris
US5850025A (en) * 1991-09-19 1998-12-15 Sibia Neurosciences, Inc. Protection of plants against plant pathogens
ATE168271T1 (de) 1992-05-23 1998-08-15 Smithkline Beecham Biolog Kombinierte impfstoffe, die hepatitis b oberfläche antigen und andere antigenen enthalten
JP3755890B2 (ja) 1992-06-25 2006-03-15 スミスクライン・ビーチャム・バイオロジカルス（ソシエテ・アノニム） アジュバント含有ワクチン組成物
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US5872098A (en) * 1995-06-05 1999-02-16 Corvas International, Inc. Nematode-extracted anticoagulant protein
US5945275A (en) * 1994-10-18 1999-08-31 Corvas International, Inc. Nematode-extracted anticoagulant protein
WO1996012021A2 (en) * 1994-10-18 1996-04-25 Corvas International, Inc. Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5866543A (en) * 1995-06-05 1999-02-02 Corvas International, Inc. Nematode-extracted anticoagulant protein
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US5716808A (en) * 1995-11-09 1998-02-10 Zymogenetics, Inc. Genetic engineering of pichia methanolica
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CA2347099C (en) 1998-10-16 2014-08-05 Smithkline Beecham Biologicals S.A. Adjuvant systems comprising an immunostimulant adsorbed to a metallic salt particle and vaccines thereof
UA79735C2 (uk) 2000-08-10 2007-07-25 Глаксосмітклайн Байолоджікалз С.А. Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах
DE60335602D1 (de) * 2002-12-18 2011-02-17 Roche Diagnostics Gmbh Rekombinante Desoxyribonuclease I aus Rinder-Pankreas mit hoher spezifischer Aktivität
DE60319333D1 (de) * 2002-12-20 2008-04-10 Roche Diagnostics Gmbh Hitzelabile Desoxyribonuklease I-Varianten
EP1460425A1 (en) * 2003-03-17 2004-09-22 Boehringer Mannheim Gmbh Deglycosylated enzymes for conjugates
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BRPI0708865A8 (pt) 2006-03-14 2019-01-22 Univ Oregon Health & Science métodos para produzir uma resposta imune à tuberculose
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FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
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NZ201705A (en) * 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
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Also Published As

Publication number Publication date
PL262598A1 (en) 1987-09-21
HUT43112A (en) 1987-09-28
ES2058055T3 (es) 1994-11-01
AU6538486A (en) 1987-05-28
NO176025B (no) 1994-10-10
NO864704D0 (no) 1986-11-25
EP0226846B1 (en) 1993-08-04
FI95929B (fi) 1995-12-29
KR920004050B1 (ko) 1992-05-23
TW215457B (fi) 1993-11-01
DK565186A (da) 1987-05-27
AU583683B2 (en) 1989-05-04
IE863021L (en) 1987-05-26
NO176025C (no) 1995-01-18
US4895800A (en) 1990-01-23
JPS62190085A (ja) 1987-08-20
MX4334A (es) 1993-12-01
FI864791A (fi) 1987-05-27
YU201386A (en) 1988-10-31
CS864186A3 (en) 1992-01-15
DK565186D0 (da) 1986-11-25
EG17949A (en) 1991-03-30
IL80754A0 (en) 1987-02-27
CN86107885A (zh) 1987-09-23
PT83819A (en) 1986-12-01
ATE92527T1 (de) 1993-08-15
YU46031B (sh) 1992-12-21
NZ218286A (en) 1991-07-26
PL152882B1 (en) 1991-02-28
EP0226846A1 (en) 1987-07-01
CA1285895C (en) 1991-07-09
ZA868601B (en) 1987-06-24
CS276453B6 (en) 1992-06-17
JPH0763372B2 (ja) 1995-07-12
IE64519B1 (en) 1995-08-09
FI95929C (fi) 1996-04-10
IN166428B (fi) 1990-05-05
IL80754A (en) 1993-03-15
PT83819B (pt) 1988-10-14
PH25539A (en) 1991-07-24
DD252614A5 (de) 1987-12-23
DE3688831D1 (de) 1993-09-09
PH25941A (en) 1991-12-19
KR870005099A (ko) 1987-06-04
DE3688831T2 (de) 1993-11-25

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Owner name: RESEARCH CORPORATION TECHNOLOGIES, INC.

GB Transfer or assigment of application

Owner name: RESEARCH CORPORATION TECHNOLOGIES, INC.

BB Publication of examined application
FG Patent granted

Owner name: RESEARCH CORPORATION TECHNOLOGIES, INC.

MA Patent expired