DE3588117T2 - Zubereitung für die Herstellung von Hepatitis B Virus-Oberflächenantigen und polymerisierten Humanserumalbuminrezeptor tragende Partikel enthaltenden Vakzinen, tierische Zellen für die Herstellung von diesen Partikeln und Verfahren für ihre Erhaltung - Google Patents
Zubereitung für die Herstellung von Hepatitis B Virus-Oberflächenantigen und polymerisierten Humanserumalbuminrezeptor tragende Partikel enthaltenden Vakzinen, tierische Zellen für die Herstellung von diesen Partikeln und Verfahren für ihre ErhaltungInfo
- Publication number
- DE3588117T2 DE3588117T2 DE3588117T DE3588117T DE3588117T2 DE 3588117 T2 DE3588117 T2 DE 3588117T2 DE 3588117 T DE3588117 T DE 3588117T DE 3588117 T DE3588117 T DE 3588117T DE 3588117 T2 DE3588117 T2 DE 3588117T2
- Authority
- DE
- Germany
- Prior art keywords
- production
- particles
- hepatitis
- surface antigen
- maintenance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002245 particle Substances 0.000 title abstract 5
- 239000000427 antigen Substances 0.000 title abstract 3
- 108091007433 antigens Proteins 0.000 title abstract 3
- 102000036639 antigens Human genes 0.000 title abstract 3
- 102000008100 Human Serum Albumin Human genes 0.000 title abstract 2
- 108091006905 Human Serum Albumin Proteins 0.000 title abstract 2
- 210000004102 animal cell Anatomy 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 2
- 241000700721 Hepatitis B virus Species 0.000 title 1
- 238000012423 maintenance Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 108020003175 receptors Proteins 0.000 title 1
- AIYUHDOJVYHVIT-UHFFFAOYSA-M caesium chloride Chemical compound [Cl-].[Cs+] AIYUHDOJVYHVIT-UHFFFAOYSA-M 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 101710132601 Capsid protein Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 208000002672 hepatitis B Diseases 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8403564A FR2560890B1 (fr) | 1984-03-07 | 1984-03-07 | Composition utile pour la fabrication de vaccins contenant des particules portant l'antigene de surface du virus de l'hepatite b et le recepteur de l'albumine serique humaine polymerisee, cellules animales capables de produire de telles particules et procede pour leur obtention |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3588117D1 DE3588117D1 (de) | 1996-09-19 |
| DE3588117T2 true DE3588117T2 (de) | 1997-03-20 |
Family
ID=9301807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE3588117T Expired - Lifetime DE3588117T2 (de) | 1984-03-07 | 1985-03-07 | Zubereitung für die Herstellung von Hepatitis B Virus-Oberflächenantigen und polymerisierten Humanserumalbuminrezeptor tragende Partikel enthaltenden Vakzinen, tierische Zellen für die Herstellung von diesen Partikeln und Verfahren für ihre Erhaltung |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP0156712B1 (de) |
| JP (1) | JPH08839B2 (de) |
| KR (1) | KR930003609B1 (de) |
| AT (1) | ATE141168T1 (de) |
| AU (1) | AU598181B2 (de) |
| CA (1) | CA1262532A (de) |
| DE (1) | DE3588117T2 (de) |
| FR (1) | FR2560890B1 (de) |
| SU (1) | SU1625332A3 (de) |
| WO (1) | WO1985003876A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL79740A0 (en) * | 1986-08-17 | 1986-11-30 | Yeda Res & Dev | Hepatitis vaccine |
| FR2608052B1 (fr) * | 1986-12-10 | 1990-04-13 | Pasteur Vaccins | Procede de preparation d'un vaccin contre l'hepatite b et vaccin obtenu |
| EP1088830A3 (de) * | 1987-06-22 | 2004-04-07 | Medeva Holdings B.V. | Partikel von Hepatitis B Oberflächenantigen |
| EP0299242A3 (de) * | 1987-06-22 | 1989-01-25 | Medico Labs Ag | Heterologe, virale, immunogen wirksame Peptidpartikel |
| KR970007153B1 (ko) * | 1987-06-22 | 1997-05-03 | 메데바 홀딩스 비브이 | B형 간염 표면 항원 백신 |
| JPH0216975A (ja) * | 1988-02-09 | 1990-01-19 | Eugene Tech Internatl Inc | 異成分混交性のプレーｓに富んだｂ型肝炎表面抗原 |
| EP0491077A1 (de) * | 1990-12-19 | 1992-06-24 | Medeva Holdings B.V. | Zusammensetzung verwendbar als therapeutisches Mittel gegen chronische virale Leberkrankheiten |
| FR2711670B1 (fr) | 1993-10-22 | 1996-01-12 | Pasteur Institut | Vecteur nucléotidique, composition le contenant et vaccin pour l'immunisation à l'encontre d'une hépatite. |
| JP4085231B2 (ja) * | 2000-02-28 | 2008-05-14 | 株式会社ビークル | タンパク質中空ナノ粒子とそれを用いた物質運搬体、ならびに細胞への物質導入方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4113712A (en) * | 1976-03-08 | 1978-09-12 | The Green Cross Corporation | HBsAG Particle composed of single polypeptide subunits and the preparation procedure |
| CA1100037A (en) * | 1977-03-11 | 1981-04-28 | Chung-Mei Ling | Hb.sub.c ag coated on solid phase |
| FI86437C (fi) * | 1978-12-22 | 1992-08-25 | Biogen Inc | Foerfarande foer framstaellning av polypeptider med de antigena egenskaperna hos ett hepatitis b- virusantigen. |
| JPS5610119A (en) * | 1979-07-05 | 1981-02-02 | Alpha Therapeutic Corp | Manufacture of b type hepatitis infection preventive vaccine |
| FR2480780B1 (fr) * | 1980-04-22 | 1985-12-06 | Pasteur Institut | Procede de transformation de cellules, notamment eucaryotes, par un adn circulaire tel que celui du virus de l'hepatite b et preparations contenant les produits d'expression desdits adn |
| DE3176404D1 (en) * | 1980-04-22 | 1987-10-08 | Pasteur Institut | Vaccine against viral hepatitis b, method and transformed eucaryotic cells for the preparation of this vaccine |
| ZW18282A1 (en) * | 1981-08-31 | 1983-03-23 | Genentech Inc | Preparation of polypeptides in vertebrate cell culture |
| JPS5936698A (ja) * | 1982-08-20 | 1984-02-28 | Science & Tech Agency | Ｂ型肝炎ウイルス遺伝子を組込んだ組換えｄｎａおよび形質転換動物細胞 |
| US4847080A (en) * | 1984-03-07 | 1989-07-11 | New York Blood Center, Inc. | Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipide vesicle carriers |
| WO1985004103A1 (en) * | 1984-03-09 | 1985-09-26 | Scripps Clinic And Research Foundation | Synthetic hepatitis b virus vaccine including both t cell anc b cell determinants |
| NL8401066A (nl) * | 1984-04-04 | 1985-11-01 | Stichting Centraal Lab | Werkwijze ter bereiding van preparaten, die de humorale en cellulaire immuunreaktiviteit vergroten. |
-
1984
- 1984-03-07 FR FR8403564A patent/FR2560890B1/fr not_active Expired
-
1985
- 1985-03-07 WO PCT/FR1985/000044 patent/WO1985003876A1/fr unknown
- 1985-03-07 AU AU40610/85A patent/AU598181B2/en not_active Expired
- 1985-03-07 DE DE3588117T patent/DE3588117T2/de not_active Expired - Lifetime
- 1985-03-07 CA CA000475890A patent/CA1262532A/fr not_active Expired
- 1985-03-07 EP EP85400444A patent/EP0156712B1/de not_active Expired - Lifetime
- 1985-03-07 EP EP95120494A patent/EP0732104A1/de not_active Withdrawn
- 1985-03-07 JP JP60501078A patent/JPH08839B2/ja not_active Expired - Lifetime
- 1985-03-07 AT AT85400444T patent/ATE141168T1/de not_active IP Right Cessation
- 1985-11-06 SU SU854011814A patent/SU1625332A3/ru active
- 1985-11-06 KR KR1019850700290A patent/KR930003609B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2560890A1 (fr) | 1985-09-13 |
| FR2560890B1 (fr) | 1987-10-16 |
| KR850700214A (ko) | 1985-12-26 |
| KR930003609B1 (ko) | 1993-05-08 |
| JPS61500971A (ja) | 1986-05-15 |
| JPH08839B2 (ja) | 1996-01-10 |
| AU4061085A (en) | 1985-09-24 |
| SU1625332A3 (ru) | 1991-01-30 |
| EP0156712A1 (de) | 1985-10-02 |
| CA1262532A (fr) | 1989-10-31 |
| AU598181B2 (en) | 1990-06-21 |
| EP0732104A1 (de) | 1996-09-18 |
| WO1985003876A1 (fr) | 1985-09-12 |
| ATE141168T1 (de) | 1996-08-15 |
| DE3588117D1 (de) | 1996-09-19 |
| EP0156712B1 (de) | 1996-08-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |