ATE62508T1 - Partikel mit immunogenen hbs-antigeneigenschaften und mit einer mit dem hbs-antigen- epitopen nichtverwandten antigenischen stelle, vektoren und tierische zellen fuer die herstellung dieser kombinierten impfstoffartikel. - Google Patents
Partikel mit immunogenen hbs-antigeneigenschaften und mit einer mit dem hbs-antigen- epitopen nichtverwandten antigenischen stelle, vektoren und tierische zellen fuer die herstellung dieser kombinierten impfstoffartikel.Info
- Publication number
- ATE62508T1 ATE62508T1 AT86400944T AT86400944T ATE62508T1 AT E62508 T1 ATE62508 T1 AT E62508T1 AT 86400944 T AT86400944 T AT 86400944T AT 86400944 T AT86400944 T AT 86400944T AT E62508 T1 ATE62508 T1 AT E62508T1
- Authority
- AT
- Austria
- Prior art keywords
- antigenic
- hbs
- particles
- vectors
- production
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 4
- 230000002163 immunogen Effects 0.000 title abstract 2
- 230000000890 antigenic effect Effects 0.000 title 3
- 229960005486 vaccine Drugs 0.000 title 1
- 239000013598 vector Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108020004511 Recombinant DNA Proteins 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 101150010882 S gene Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8506708A FR2581394B1 (fr) | 1985-05-02 | 1985-05-02 | Particules ayant les proprietes immunogenes de l'antigene hbs et portant un site antigenique etranger aux epitopes portes par l'antigene hbs, vecteurs et cellules animales pour la production de telles particules et compositions contenant de telles particules pour la production de vaccins mixtes |
EP86400944A EP0201416B1 (de) | 1985-05-02 | 1986-04-29 | Partikel mit immunogenen HBs-Antigen-Eigenschaften und mit einer mit dem HBs-Antigen-Epitopen nichtverwandten antigenischen Stelle, Vektoren und tierische Zellen für die Herstellung dieser kombinierten Impfstoffartikel |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE62508T1 true ATE62508T1 (de) | 1991-04-15 |
Family
ID=9318908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT86400944T ATE62508T1 (de) | 1985-05-02 | 1986-04-29 | Partikel mit immunogenen hbs-antigeneigenschaften und mit einer mit dem hbs-antigen- epitopen nichtverwandten antigenischen stelle, vektoren und tierische zellen fuer die herstellung dieser kombinierten impfstoffartikel. |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0201416B1 (de) |
JP (2) | JPH088869B2 (de) |
AT (1) | ATE62508T1 (de) |
CA (1) | CA1282021C (de) |
DE (1) | DE3678609D1 (de) |
DK (1) | DK166357C (de) |
ES (1) | ES8703520A1 (de) |
FR (1) | FR2581394B1 (de) |
GR (1) | GR861141B (de) |
PT (1) | PT82500B (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0278940A3 (de) * | 1987-01-30 | 1988-12-07 | Smithkline Biologicals S.A. | Hepatitis-B-Virus-Oberflächenantigene und sie enthaltende hybride Antigene |
DE10299017I2 (de) * | 1987-06-22 | 2005-05-25 | Medeva Holdings Bv | Hepatitis-B-Oberfl{chenantigen enthaltendes Peptid. |
FR2635532B1 (fr) * | 1988-07-29 | 1992-05-22 | Pasteur Institut | Particules hbsag recombinantes hybrides : caracteristiques morphologiques de l'antigene hbsag contenant 1 sequence immunogene induisant des anticorps neutralisants diriges contre hiv ou susceptible d'etre reconnue par de tels anticorps; sequences nucleotidiques codant pour de telles particules; vaccins les contenant |
EP0491077A1 (de) * | 1990-12-19 | 1992-06-24 | Medeva Holdings B.V. | Zusammensetzung verwendbar als therapeutisches Mittel gegen chronische virale Leberkrankheiten |
EP1233783B9 (de) * | 1999-11-24 | 2006-03-15 | Chiron Corporation | HBV/HCV Virus-ºhnliche Particle |
US6740323B1 (en) | 1999-11-24 | 2004-05-25 | Chiron Corporation | HBV/HCV virus-like particle |
JP4085231B2 (ja) * | 2000-02-28 | 2008-05-14 | 株式会社ビークル | タンパク質中空ナノ粒子とそれを用いた物質運搬体、ならびに細胞への物質導入方法 |
US7094409B2 (en) | 2001-01-19 | 2006-08-22 | Cytos Biotechnology Ag | Antigen arrays for treatment of allergic eosinophilic diseases |
US7128911B2 (en) | 2001-01-19 | 2006-10-31 | Cytos Biotechnology Ag | Antigen arrays for treatment of bone disease |
AU2002339224B2 (en) | 2001-09-14 | 2008-10-09 | Kuros Us Llc | Packaging of immunostimulatory substances into virus-like particles: method of preparation and use |
US7115266B2 (en) | 2001-10-05 | 2006-10-03 | Cytos Biotechnology Ag | Angiotensin peptide-carrier conjugates and uses thereof |
JP2003286199A (ja) * | 2002-03-29 | 2003-10-07 | Japan Science & Technology Corp | タンパク質中空ナノ粒子を用いる肝臓疾患治療用薬剤 |
JP2003286198A (ja) * | 2002-03-29 | 2003-10-07 | Japan Science & Technology Corp | 増殖因子等を提示するタンパク質中空ナノ粒子を用いる治療薬剤 |
JP2003286189A (ja) * | 2002-03-29 | 2003-10-07 | Japan Science & Technology Corp | 中空ナノ粒子を形成するタンパク質に疾患治療用の細胞導入物質を融合させた薬剤 |
JP2004081210A (ja) * | 2002-06-28 | 2004-03-18 | Japan Science & Technology Corp | システイン残基を改変したタンパク質からなる中空ナノ粒子およびそれを用いた薬剤 |
WO2004071493A1 (en) * | 2003-02-17 | 2004-08-26 | Peter Burkhard | Peptidic nanoparticles as drug delivery and antigen display systems |
EP1605973B1 (de) | 2003-03-26 | 2012-09-26 | Cytos Biotechnology AG | Verpacken von immunostimulierenden oligonukleotiden in virus-ähnliche partikel, verfahren zu deren herstellung sowie deren verwendungen |
US7537767B2 (en) | 2003-03-26 | 2009-05-26 | Cytis Biotechnology Ag | Melan-A- carrier conjugates |
EP2766386A1 (de) | 2011-10-12 | 2014-08-20 | Alpha-o Peptides AG | Selbstanordnende peptid-nanoteilchen als impfstoffe gegen eine norovirus-infektion |
WO2014103608A1 (ja) | 2012-12-25 | 2014-07-03 | 一般財団法人化学及血清療法研究所 | HPV/HBsキメラタンパク質を有効成分とするHPV感染症及び/又はB型肝炎用ワクチン |
US10279019B2 (en) | 2014-02-11 | 2019-05-07 | Stc.Unm | PCSK9 peptide vaccine conjugated to a Qbeta carrier and methods of using the same |
EP3585428A1 (de) | 2017-02-23 | 2020-01-01 | Alpha-o Peptides AG | Selbstanordnende proteinnanopartikel zur einkapselung von immunstimulierenden nukleinsäuren |
EA201991918A1 (ru) | 2017-03-23 | 2020-05-15 | Альфа-О Пептидс Аг | Самосборные белковые наночастицы со встроенными белками с шестиспиральным пучком |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4415491A (en) * | 1980-01-14 | 1983-11-15 | The Regents Of The University Of California | Synthetic vaccine peptide epitomes of hepatitis B surface antigen |
FR2532850B1 (fr) * | 1982-09-15 | 1985-12-20 | Pasteur Institut | Conjugues immunogenes entre un haptene et une molecule porteuse derivee d'une toxine, les vaccins les composant et procede pour leur obtention |
US4483793A (en) * | 1982-10-04 | 1984-11-20 | The Regents Of The University Of California | Dimeric oligopeptides as heptenic epitopic sites for hepatitis |
FR2550203B1 (fr) * | 1983-08-01 | 1985-11-22 | Anvar | Peptides synthetiques immunogenes porteurs d'un epitope caracteristique de l'antigene de surface du virus de l'hepatite b et compositions les contenant |
FR2569984B1 (fr) * | 1984-09-12 | 1987-08-14 | Anvar | Molecule synthetique contenant une pluralite d'epitopes distincts, procede pour son obtention et application a la production de polyvaccins |
-
1985
- 1985-05-02 FR FR8506708A patent/FR2581394B1/fr not_active Expired
-
1986
- 1986-04-29 AT AT86400944T patent/ATE62508T1/de not_active IP Right Cessation
- 1986-04-29 DE DE8686400944T patent/DE3678609D1/de not_active Expired - Fee Related
- 1986-04-29 EP EP86400944A patent/EP0201416B1/de not_active Expired - Lifetime
- 1986-04-29 GR GR861141A patent/GR861141B/el unknown
- 1986-05-02 PT PT82500A patent/PT82500B/pt not_active IP Right Cessation
- 1986-05-02 JP JP61102929A patent/JPH088869B2/ja not_active Expired - Lifetime
- 1986-05-02 ES ES555124A patent/ES8703520A1/es not_active Expired
- 1986-05-02 CA CA000508233A patent/CA1282021C/fr not_active Expired - Fee Related
- 1986-05-02 DK DK202586A patent/DK166357C/da not_active IP Right Cessation
-
1995
- 1995-07-24 JP JP7187404A patent/JPH08198897A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DK166357C (da) | 1993-09-06 |
PT82500B (pt) | 1989-05-12 |
ES8703520A1 (es) | 1987-03-01 |
JPS61258000A (ja) | 1986-11-15 |
EP0201416A1 (de) | 1986-11-12 |
CA1282021C (fr) | 1991-03-26 |
ES555124A0 (es) | 1987-03-01 |
PT82500A (fr) | 1986-06-01 |
GR861141B (en) | 1986-08-21 |
DK202586A (da) | 1986-11-03 |
FR2581394A1 (fr) | 1986-11-07 |
EP0201416B1 (de) | 1991-04-10 |
DE3678609D1 (de) | 1991-05-16 |
JPH08198897A (ja) | 1996-08-06 |
DK166357B (da) | 1993-04-13 |
DK202586D0 (da) | 1986-05-02 |
FR2581394B1 (fr) | 1988-08-05 |
JPH088869B2 (ja) | 1996-01-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |