DK202586A - Partikler med immunogene egenskaber svarende til antigen hbs, vektorerog animalske celler til produktion af saadanne partikler samt anvendelse af disse til fremstilling af blandede vacciner - Google Patents

Partikler med immunogene egenskaber svarende til antigen hbs, vektorerog animalske celler til produktion af saadanne partikler samt anvendelse af disse til fremstilling af blandede vacciner Download PDF

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Publication number
DK202586A
DK202586A DK202586A DK202586A DK202586A DK 202586 A DK202586 A DK 202586A DK 202586 A DK202586 A DK 202586A DK 202586 A DK202586 A DK 202586A DK 202586 A DK202586 A DK 202586A
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DK
Denmark
Prior art keywords
particles
vector
producing
preparation
animal cells
Prior art date
Application number
DK202586A
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English (en)
Other versions
DK202586D0 (da
DK166357B (da
DK166357C (da
Inventor
Francis Delpeyroux
Nicole Chenciner
Annick Lim
Yves Malpiece
Rolf Streeck
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Pasteur Institut filed Critical Pasteur Institut
Publication of DK202586D0 publication Critical patent/DK202586D0/da
Publication of DK202586A publication Critical patent/DK202586A/da
Publication of DK166357B publication Critical patent/DK166357B/da
Application granted granted Critical
Publication of DK166357C publication Critical patent/DK166357C/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/32011Picornaviridae
    • C12N2770/32611Poliovirus
    • C12N2770/32622New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK202586A 1985-05-02 1986-05-02 Partikler med immunogene egenskaber svarende til hbs antigen samt vektorer og animalske celler til produktion af saadanne partikler DK166357C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8506708 1985-05-02
FR8506708A FR2581394B1 (fr) 1985-05-02 1985-05-02 Particules ayant les proprietes immunogenes de l'antigene hbs et portant un site antigenique etranger aux epitopes portes par l'antigene hbs, vecteurs et cellules animales pour la production de telles particules et compositions contenant de telles particules pour la production de vaccins mixtes

Publications (4)

Publication Number Publication Date
DK202586D0 DK202586D0 (da) 1986-05-02
DK202586A true DK202586A (da) 1986-11-03
DK166357B DK166357B (da) 1993-04-13
DK166357C DK166357C (da) 1993-09-06

Family

ID=9318908

Family Applications (1)

Application Number Title Priority Date Filing Date
DK202586A DK166357C (da) 1985-05-02 1986-05-02 Partikler med immunogene egenskaber svarende til hbs antigen samt vektorer og animalske celler til produktion af saadanne partikler

Country Status (10)

Country Link
EP (1) EP0201416B1 (da)
JP (2) JPH088869B2 (da)
AT (1) ATE62508T1 (da)
CA (1) CA1282021C (da)
DE (1) DE3678609D1 (da)
DK (1) DK166357C (da)
ES (1) ES8703520A1 (da)
FR (1) FR2581394B1 (da)
GR (1) GR861141B (da)
PT (1) PT82500B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0278940A3 (en) * 1987-01-30 1988-12-07 Smithkline Biologicals S.A. Hepatitis b virus surface antigens and hybrid antigens containing them
IL86833A0 (en) * 1987-06-22 1988-11-30 Medico Labs Peptide containing immunogenic particles
FR2635532B1 (fr) * 1988-07-29 1992-05-22 Pasteur Institut Particules hbsag recombinantes hybrides : caracteristiques morphologiques de l'antigene hbsag contenant 1 sequence immunogene induisant des anticorps neutralisants diriges contre hiv ou susceptible d'etre reconnue par de tels anticorps; sequences nucleotidiques codant pour de telles particules; vaccins les contenant
EP0491077A1 (en) * 1990-12-19 1992-06-24 Medeva Holdings B.V. A composition used as a therapeutic agent against chronic viral hepatic diseases
US6740323B1 (en) 1999-11-24 2004-05-25 Chiron Corporation HBV/HCV virus-like particle
ATE290399T1 (de) * 1999-11-24 2005-03-15 Chiron Corp Hbv/hcv virus-ohnliche particle
JP4085231B2 (ja) * 2000-02-28 2008-05-14 株式会社ビークル タンパク質中空ナノ粒子とそれを用いた物質運搬体、ならびに細胞への物質導入方法
US7128911B2 (en) 2001-01-19 2006-10-31 Cytos Biotechnology Ag Antigen arrays for treatment of bone disease
US7094409B2 (en) 2001-01-19 2006-08-22 Cytos Biotechnology Ag Antigen arrays for treatment of allergic eosinophilic diseases
AU2002339224B2 (en) 2001-09-14 2008-10-09 Kuros Us Llc Packaging of immunostimulatory substances into virus-like particles: method of preparation and use
US7115266B2 (en) 2001-10-05 2006-10-03 Cytos Biotechnology Ag Angiotensin peptide-carrier conjugates and uses thereof
JP2003286189A (ja) * 2002-03-29 2003-10-07 Japan Science & Technology Corp 中空ナノ粒子を形成するタンパク質に疾患治療用の細胞導入物質を融合させた薬剤
JP2003286198A (ja) * 2002-03-29 2003-10-07 Japan Science & Technology Corp 増殖因子等を提示するタンパク質中空ナノ粒子を用いる治療薬剤
JP2003286199A (ja) * 2002-03-29 2003-10-07 Japan Science & Technology Corp タンパク質中空ナノ粒子を用いる肝臓疾患治療用薬剤
US20060141042A1 (en) * 2002-06-28 2006-06-29 Shunichi Kuroda Hollow nanoparticle having modified cysteine residue and drug with the use thereof
JP4509999B2 (ja) * 2003-02-17 2010-07-21 ブルクハルト,ペーター 医薬送達及び抗原提示システムとしてのペプチドナノ粒子
KR20050115913A (ko) 2003-03-26 2005-12-08 사이토스 바이오테크놀로지 아게 Melan―a 펩티드 유사체-바이러스-양-입자컨쥬게이트
US7537767B2 (en) 2003-03-26 2009-05-26 Cytis Biotechnology Ag Melan-A- carrier conjugates
US20140242104A1 (en) 2011-10-12 2014-08-28 Alpha-O Peptides Ag Self-assembling peptide nanoparticles as vaccines against infection with norovirus
WO2014103608A1 (ja) 2012-12-25 2014-07-03 一般財団法人化学及血清療法研究所 HPV/HBsキメラタンパク質を有効成分とするHPV感染症及び/又はB型肝炎用ワクチン
EP3104877B1 (en) 2014-02-11 2020-01-22 The USA, as represented by The Secretary, Department of Health and Human Services Pcsk9 vaccine and methods of using the same
WO2018154010A1 (en) 2017-02-23 2018-08-30 Alpha-O Peptides Ag Self-assembling protein nanoparticles encapsulating immunostimulatory nucleid acids
WO2018172447A1 (en) 2017-03-23 2018-09-27 Alpha-O Peptides Ag Self-assembling protein nanoparticles with built-in six-helix bundle proteins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415491A (en) * 1980-01-14 1983-11-15 The Regents Of The University Of California Synthetic vaccine peptide epitomes of hepatitis B surface antigen
FR2532850B1 (fr) * 1982-09-15 1985-12-20 Pasteur Institut Conjugues immunogenes entre un haptene et une molecule porteuse derivee d'une toxine, les vaccins les composant et procede pour leur obtention
US4483793A (en) * 1982-10-04 1984-11-20 The Regents Of The University Of California Dimeric oligopeptides as heptenic epitopic sites for hepatitis
FR2550203B1 (fr) * 1983-08-01 1985-11-22 Anvar Peptides synthetiques immunogenes porteurs d'un epitope caracteristique de l'antigene de surface du virus de l'hepatite b et compositions les contenant
FR2569984B1 (fr) * 1984-09-12 1987-08-14 Anvar Molecule synthetique contenant une pluralite d'epitopes distincts, procede pour son obtention et application a la production de polyvaccins

Also Published As

Publication number Publication date
JPS61258000A (ja) 1986-11-15
DK202586D0 (da) 1986-05-02
FR2581394B1 (fr) 1988-08-05
ATE62508T1 (de) 1991-04-15
DE3678609D1 (de) 1991-05-16
GR861141B (en) 1986-08-21
DK166357B (da) 1993-04-13
PT82500A (fr) 1986-06-01
EP0201416B1 (fr) 1991-04-10
JPH088869B2 (ja) 1996-01-31
FR2581394A1 (fr) 1986-11-07
CA1282021C (fr) 1991-03-26
EP0201416A1 (fr) 1986-11-12
ES8703520A1 (es) 1987-03-01
PT82500B (pt) 1989-05-12
ES555124A0 (es) 1987-03-01
JPH08198897A (ja) 1996-08-06
DK166357C (da) 1993-09-06

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