ATE89317T1 - Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten. - Google Patents

Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten.

Info

Publication number
ATE89317T1
ATE89317T1 AT88301887T AT88301887T ATE89317T1 AT E89317 T1 ATE89317 T1 AT E89317T1 AT 88301887 T AT88301887 T AT 88301887T AT 88301887 T AT88301887 T AT 88301887T AT E89317 T1 ATE89317 T1 AT E89317T1
Authority
AT
Austria
Prior art keywords
proteins
expression vectors
dna encoding
cmpd
cells containing
Prior art date
Application number
AT88301887T
Other languages
English (en)
Inventor
Keith C Backman
Ramaswamy Balakrishnan
Original Assignee
Bioteknika International
Heinz Co H J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioteknika International, Heinz Co H J filed Critical Bioteknika International
Application granted granted Critical
Publication of ATE89317T1 publication Critical patent/ATE89317T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/222—Phenylalanine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT88301887T 1986-05-07 1988-03-03 Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten. ATE89317T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/860,541 US4753883A (en) 1986-05-07 1986-05-07 Enzyme deregulation
EP88301887A EP0330773B1 (de) 1986-05-07 1988-03-03 Proteine, Expressionsvektoren, die für solche Proteine kodierende DNA enthalten und Zellen, die solche Expressionsvektoren enthalten

Publications (1)

Publication Number Publication Date
ATE89317T1 true ATE89317T1 (de) 1993-05-15

Family

ID=25333456

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88301887T ATE89317T1 (de) 1986-05-07 1988-03-03 Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten.

Country Status (5)

Country Link
US (1) US4753883A (de)
EP (1) EP0330773B1 (de)
AT (1) ATE89317T1 (de)
CA (1) CA1295565C (de)
DE (1) DE3881023T2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753883A (en) * 1986-05-07 1988-06-28 Biotechnica International, Inc. Enzyme deregulation
US5120837A (en) * 1989-09-20 1992-06-09 The Nutrasweet Company Dna encoding phe a feedback inhibition resistant enzyme analogues
DE69124939T2 (de) * 1990-11-30 1997-10-02 Ajinomoto Kk Rekombinante DNS-Sequenzen kodierend für Enzyme frei von Feedback Inhibition, Plasmide diese Sequenzen enthaltend, transformierte Mikroorganismen nützlich für Produktion von aromatischen Aminosäuren, und deren Verfahren zur Herstellung durch Fermentation
US5168056A (en) * 1991-02-08 1992-12-01 Purdue Research Foundation Enhanced production of common aromatic pathway compounds
TW313589B (de) * 1991-12-12 1997-08-21 Wacker Chemie Gmbh
US5856148A (en) * 1991-12-12 1999-01-05 Wacker Chemie Gmbh Materials and methods for biosynthesis of serine and serine-related products
US5776736A (en) * 1992-12-21 1998-07-07 Purdue Research Foundation Deblocking the common pathway of aromatic amino acid synthesis
US5487987A (en) * 1993-09-16 1996-01-30 Purdue Research Foundation Synthesis of adipic acid from biomass-derived carbon sources
US5629181A (en) * 1993-09-16 1997-05-13 Purdue Research Foundation Synthesis of catechol from biomass-derived carbon sources
US5728555A (en) * 1996-09-30 1998-03-17 Monsanto Company Preparation of d-amino acids by direct fermentative means
US6465217B1 (en) * 2000-07-05 2002-10-15 Paradigm Genetics, Inc. Methods and compositions for the modulation of chorismate synthase and chorismate mutase expression or activity in plants
RU2250261C1 (ru) * 2003-09-30 2005-04-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) ПРЕФЕНАТДЕГИДРАТАЗА-ХОРИЗМАТМУТАЗА И ФРАГМЕНТ ДНК, КОДИРУЮЩИЙ ПРЕФЕНАТДЕГИДРАТАЗУ-ХОРИЗМАТМУТАЗУ, ИЗ БАКТЕРИИ Methylophilus methylotrophus
CA2862051A1 (en) 2012-01-30 2013-08-08 Myriant Corporation Production of muconic acid from genetically engineered microorganisms
CN109415684B (zh) 2016-03-02 2022-06-07 Ptt全球化学公众有限公司 从基因工程微生物改进的黏康酸生产
KR20220140619A (ko) 2020-03-18 2022-10-18 란자테크, 인크. 가스성 기질로부터의 2-페닐에탄올의 발효 제조

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS561890A (en) * 1979-06-15 1981-01-10 Ajinomoto Co Inc Preparation of l-phenylalanine by fermentation
AU550349B2 (en) * 1980-07-18 1986-03-20 Austgen-Biojet International Pty. Ltd. Novel e.coli and phenylalanine production
DE3128411A1 (de) * 1980-07-18 1983-09-15 Unisearch Ltd., 2033 Kensington, New South Wales Kulturstamm-mutante von esccherichia coli sowie verfahren zur herstellung von phenylalanin
US4839286A (en) * 1983-10-07 1989-06-13 Biotechnica International, Inc. Method of biosynthesis and cells therefor
CA1283375C (en) * 1984-09-24 1991-04-23 H.J. Heinz Company Method of biosynthesis and cells therefor
JPS61247392A (ja) * 1985-02-04 1986-11-04 エンジニツクス　インコ−ポレ−テツド ２種またはより多くのアミノ酸を同時に産生できる組換え微生物
WO1987000202A1 (en) * 1985-06-24 1987-01-15 The Nutrasweet Company Composite plasmids for amino acid synthesis
US4753883A (en) * 1986-05-07 1988-06-28 Biotechnica International, Inc. Enzyme deregulation

Also Published As

Publication number Publication date
US4753883A (en) 1988-06-28
DE3881023D1 (de) 1993-06-17
EP0330773B1 (de) 1993-05-12
EP0330773A1 (de) 1989-09-06
CA1295565C (en) 1992-02-11
DE3881023T2 (de) 1993-11-25

Similar Documents

Publication Publication Date Title
ATE89317T1 (de) Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten.
BG60256B1 (bg) Рекомбинантен метод за получаване на лимфотоксин
IL173399A0 (en) Circular dna molecule with conditional origin of replication which contains nucleic acid of interest and selection marker but does not encode its replication initiation protein, method for preparing the same and use thereof in gene therapy
ATE42114T1 (de) Mikrobiologisch hergestelltes interferon alpha2(arg), dna-sequenz, die fuer dieses interferon codiert, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung.
HUP0000810A2 (hu) Esszenciális aminosavakat nagy mennyiségben tartalmazó fehérjék
AU595221B2 (en) Fusion proteins, a process for their preparation and their use
IT8119760A0 (it) Polipeptide prodotto microbiologicamente con la sequenza di aminoacidi dell'interferone umano, dna e plasmidi che codificano per questa sequenza, microorganismi che contengono queste informazioni genetiche e processo per la loro preparazione.
DK164940C (da) Polypeptid med human-gamma-interferonaktivitet, genteknologisk fremgangsmaade til fremstilling deraf, hybrid-plasmider indeholdende en dna-sekvens, der koder for peptidet, vaertsorganismer indeholdende hybridplasmiderne, samt laegemidler, som indeholder polypeptidet
IL81018A (en) Fusion proteins comprising small fragments of human interleukin-2 as ballast,process for its preparation and genes,vectors and transformed host containing said fragments and used in the process
DE68925869D1 (de) Modifizierte Proteine, modifizierte Interferone alpha- und beta-phosphorylierte Proteine, DNA-Sequenzen und Analoge und deren Verwendung
ATE256182T1 (de) Neuartiges p- selectin ligandenprotein
CA2066370A1 (en) Yield when disulfide-bonded proteins are secreted
AU8223387A (en) Horse gamma-interferon
IL88151A (en) Interleukin-7 protein, dna sequences encoding it, its preparation and compositions containing it
EP1449849A3 (de) Protease-resistentes Thrombomodulinanalog
DK0386752T3 (da) Polypeptid og fremstilling heraf
DE3856240D1 (de) Herstellung der p1 proteine und impfstoffe gegen gonorrhöe
IT8119759A0 (it) Umano, dna e plasmidi che polipeptide prodotto codificano per questa sequenza, microbiologicamente con la sequenza microorganismi che contengono di aminoacidi dell'interferone queste informazioni genetiche e processo per la loro preparazione.
KR880701073A (ko) 제조합 dna 기법에 의해 생성된 민악티빈
ATE5151T1 (de) Mikrobiologisch hergestelltes polypeptid mit der aminosaeuresequenz des proinsulins von affen, dna und plasmide, die fuer diese sequenz codieren, mikroorganismen, die diese genetischen informationen enthalten, und verfahren zu deren herstellung.
KR860008282A (ko) 재조합 사람 레닌의 제조방법
ES2061574T3 (es) Acil-peptido-hidrolasa y metodos de produccion y uso.
TH34143A (th) การใส่รหัสของยีนส์ชนิดใหม่สำหรับอะมีโมเอชิดดีเอซิทิเลสซึ่งมีฤทธิ์โดยเฉพาะเจาะจงกับ n-เอชิทิล-l ฟอสฟิโนไทรซิน, กรรมวิธีการแยก และการนำมาใช้ของสารนี้

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee