IL85759A0 - The cloning of malaria-specific dna sequences,isolation of the gene for the 140 kd protein - Google Patents
The cloning of malaria-specific dna sequences,isolation of the gene for the 140 kd proteinInfo
- Publication number
- IL85759A0 IL85759A0 IL85759A IL8575988A IL85759A0 IL 85759 A0 IL85759 A0 IL 85759A0 IL 85759 A IL85759 A IL 85759A IL 8575988 A IL8575988 A IL 8575988A IL 85759 A0 IL85759 A0 IL 85759A0
- Authority
- IL
- Israel
- Prior art keywords
- gene
- protein
- malaria
- cloning
- isolation
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- 238000010367 cloning Methods 0.000 title 1
- 238000002955 isolation Methods 0.000 title 1
- 201000004792 malaria Diseases 0.000 title 1
- 241000223960 Plasmodium falciparum Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The gene coding for a 140 kD antigen of P. falciparum was isolated, sequenced and expressed in cells transformed with it. The expressed protein or parts thereof are suitable as vaccines or it or the gene can be employed for the production of diagnostics.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3708783 | 1987-03-18 | ||
DE19873741057 DE3741057A1 (en) | 1987-03-18 | 1987-12-04 | CLONING OF MALARIA-SPECIFIC DNA SEQUENCES: ISOLATING THE GENE FOR THE 140 KD PROTEIN |
Publications (2)
Publication Number | Publication Date |
---|---|
IL85759A0 true IL85759A0 (en) | 1988-08-31 |
IL85759A IL85759A (en) | 1995-06-29 |
Family
ID=25853634
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL8575988A IL85759A (en) | 1987-03-18 | 1988-03-16 | Dna or rna sequence encoding the 140 kd antigen of plamodium falciparum vectors and host cells containing them and vaccines containing antigens prepared in said cells |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0283882B1 (en) |
JP (1) | JPS63267293A (en) |
AT (1) | ATE188997T1 (en) |
AU (1) | AU611132B2 (en) |
DE (2) | DE3741057A1 (en) |
DK (1) | DK145988A (en) |
IL (1) | IL85759A (en) |
NZ (1) | NZ223907A (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990001549A2 (en) * | 1988-08-12 | 1990-02-22 | Trustees Of Dartmouth College | Gene encoding protein antigens of plasmodium falciparum |
US6333406B1 (en) | 1988-08-12 | 2001-12-25 | Joseph W. Inselburg | Gene encoding protein antigens of Plasmodium falciparum and uses therefor |
EP0474891A1 (en) * | 1990-09-08 | 1992-03-18 | BEHRINGWERKE Aktiengesellschaft | Vectors for expression of malarial antigens on the surface of Salmonella vaccine strains |
DE4041836A1 (en) * | 1990-12-24 | 1992-06-25 | Behringwerke Ag | PROTECTIVE PLASMODIUM FALCIPARUM HYBRID PROTEINS COMPRISING PARTIAL SEQUENCES OF MALARIA ANTIGENE HRPII AND SERP, THEIR PREPARATION AND USE |
EP1279735B1 (en) | 2001-01-24 | 2009-09-09 | The Research Foundation for Microbial Diseases of Osaka University | Malaria plasmodium antigen polypeptide se36, method of purifying the same and vaccine and diagnostic with the use of the thus obtained antigen |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU569722B2 (en) * | 1983-01-28 | 1988-02-18 | Saramane Pty Ltd | Expression of plasmodium falciparum polypeptides from cloned cdna |
GB8404378D0 (en) * | 1984-02-20 | 1984-03-28 | Biogen Nv | Dna sequence recombinant dna molecules |
EP0215059A4 (en) * | 1985-02-20 | 1988-04-13 | Sloan Kettering Inst Cancer | cDNA CODING FOR PLASMODIUM FALCIPARUM GLYCOPHORIN BINDING PROTEINS WEIGHING 130,000 DALTONS AND 155,000 DALTONS. |
-
1987
- 1987-12-04 DE DE19873741057 patent/DE3741057A1/en not_active Withdrawn
-
1988
- 1988-03-12 AT AT88103949T patent/ATE188997T1/en not_active IP Right Cessation
- 1988-03-12 DE DE3856392T patent/DE3856392D1/en not_active Expired - Fee Related
- 1988-03-12 EP EP88103949A patent/EP0283882B1/en not_active Expired - Lifetime
- 1988-03-16 NZ NZ223907A patent/NZ223907A/en unknown
- 1988-03-16 IL IL8575988A patent/IL85759A/en not_active IP Right Cessation
- 1988-03-17 JP JP63064685A patent/JPS63267293A/en active Pending
- 1988-03-17 DK DK145988A patent/DK145988A/en not_active Application Discontinuation
- 1988-03-17 AU AU13219/88A patent/AU611132B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
DK145988A (en) | 1988-09-19 |
DE3856392D1 (en) | 2000-02-24 |
AU1321988A (en) | 1988-09-22 |
EP0283882A1 (en) | 1988-09-28 |
DE3741057A1 (en) | 1988-09-29 |
EP0283882B1 (en) | 2000-01-19 |
NZ223907A (en) | 1991-05-28 |
AU611132B2 (en) | 1991-06-06 |
JPS63267293A (en) | 1988-11-04 |
DK145988D0 (en) | 1988-03-17 |
IL85759A (en) | 1995-06-29 |
ATE188997T1 (en) | 2000-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HP | Change in proprietorship | ||
RH | Patent void |