EG17949A - Yeast production of hepatitis b surface antigen - Google Patents

Yeast production of hepatitis b surface antigen

Info

Publication number
EG17949A
EG17949A EG733/86A EG73386A EG17949A EG 17949 A EG17949 A EG 17949A EG 733/86 A EG733/86 A EG 733/86A EG 73386 A EG73386 A EG 73386A EG 17949 A EG17949 A EG 17949A
Authority
EG
Egypt
Prior art keywords
hepatitis
surface antigen
regulatory regions
yeast production
carbon sources
Prior art date
Application number
EG733/86A
Other languages
English (en)
Original Assignee
Phillips Petroleum Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phillips Petroleum Co filed Critical Phillips Petroleum Co
Application granted granted Critical
Publication of EG17949A publication Critical patent/EG17949A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Beans For Foods Or Fodder (AREA)
EG733/86A 1985-11-26 1986-11-24 Yeast production of hepatitis b surface antigen EG17949A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/801,713 US4895800A (en) 1985-11-26 1985-11-26 Yeast production of hepatitis B surface antigen

Publications (1)

Publication Number Publication Date
EG17949A true EG17949A (en) 1991-03-30

Family

ID=25181867

Family Applications (1)

Application Number Title Priority Date Filing Date
EG733/86A EG17949A (en) 1985-11-26 1986-11-24 Yeast production of hepatitis b surface antigen

Country Status (28)

Country Link
US (1) US4895800A (pt)
EP (1) EP0226846B1 (pt)
JP (1) JPH0763372B2 (pt)
KR (1) KR920004050B1 (pt)
CN (1) CN86107885A (pt)
AT (1) ATE92527T1 (pt)
AU (1) AU583683B2 (pt)
CA (1) CA1285895C (pt)
CS (1) CS276453B6 (pt)
DD (1) DD252614A5 (pt)
DE (1) DE3688831T2 (pt)
DK (1) DK565186A (pt)
EG (1) EG17949A (pt)
ES (1) ES2058055T3 (pt)
FI (1) FI95929C (pt)
HU (1) HUT43112A (pt)
IE (1) IE64519B1 (pt)
IL (1) IL80754A (pt)
IN (1) IN166428B (pt)
MX (1) MX4334A (pt)
NO (1) NO176025C (pt)
NZ (1) NZ218286A (pt)
PH (2) PH25941A (pt)
PL (1) PL152882B1 (pt)
PT (1) PT83819B (pt)
TW (1) TW215457B (pt)
YU (1) YU46031B (pt)
ZA (1) ZA868601B (pt)

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US4683293A (en) * 1986-10-20 1987-07-28 Phillips Petroleum Company Purification of pichia produced lipophilic proteins
US5026828A (en) * 1987-02-27 1991-06-25 Merck & Co., Inc. Method of purifying recombinant pres-1/S-2/S/S hepatitis B antigen from yeast
ATE91304T1 (de) * 1987-02-27 1993-07-15 Merck & Co Inc Verfahren zur herstellung des pres 1/s2/shepatitis-b-antigens aus hefe.
EP0291146B1 (en) * 1987-03-09 1993-09-01 Merck & Co. Inc. Purification of recombinant hepatitis b surface antigen
DE10299017I2 (de) * 1987-06-22 2005-05-25 Medeva Holdings Bv Hepatitis-B-Oberfl{chenantigen enthaltendes Peptid.
US5011915A (en) * 1987-10-26 1991-04-30 Merck & Co., Inc. Process for purifying recombinant hepatitis antigens
EP0314240A3 (en) * 1987-10-26 1990-03-28 Merck & Co. Inc. Process for purifying recombinant hepatitis antigens
US5004688A (en) * 1988-04-15 1991-04-02 Phillips Petroleum Company Purification of hepatitis proteins
IL89989A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human interleukin-2 in methylotrophic yeasts
NZ228774A (en) * 1988-04-25 1991-05-28 Phillips Petroleum Co Hbv particles containing pres 2 proteins and recombinant processes for their production in yeast cells
IL89993A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of the hiv 24kda gag protein in methylotrophic yeasts
IL90021A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Process for the production of interferon
IL89992A0 (en) * 1988-04-25 1989-12-15 Phillips Petroleum Co Expression of human serum albumin in methylotrophic yeasts
IL90161A0 (en) * 1988-05-13 1989-12-15 Phillips Petroleum Co Expression of hepatitis b s and pres2 proteins in methylotrophic yeasts
WO1990003431A1 (en) * 1988-09-26 1990-04-05 The Salk Institute Biotechnology/Industrial Associates, Inc. Mixed feed recombinant yeast fermentation
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CA2090969C (en) * 1990-09-04 2001-08-21 Russell Arthur Brierley Production of insulin-like growth factor-1 in methylotrophic yeast cells
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
CU22290A1 (es) * 1990-10-08 1995-01-31 Cigb Procedimiento para la obtencion de antigeno de superficie del virus de la hepatitis b de superior capacidad inmunoganica y su uso en un preparado vacunal
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EP0491077A1 (en) * 1990-12-19 1992-06-24 Medeva Holdings B.V. A composition used as a therapeutic agent against chronic viral hepatic diseases
WO1992013951A1 (en) * 1991-02-04 1992-08-20 The Salk Institute Biotechnology/Industrial Associates, Inc. Production of human serum albumin in methylotrophic yeast cells
CA2063890C (en) * 1991-03-27 2007-03-13 Masami Miura Mutant aox2 promoter, microorganism carrying same, method of preparation thereof and production of heterologous protein using such microorganism
EP0578746B1 (en) * 1991-04-01 2002-07-03 Merck & Co., Inc. GENES WHICH INFLUENCE $i(PICHIA) PROTEOLYTIC ACTIVITY, AND USES THEREFOR
CA2058820C (en) * 1991-04-25 2003-07-15 Kotikanyad Sreekrishna Expression cassettes and vectors for the secretion of human serum albumin in pichia pastoris cells
US5330901A (en) * 1991-04-26 1994-07-19 Research Corporation Technologies, Inc. Expression of human serum albumin in Pichia pastoris
US5850025A (en) * 1991-09-19 1998-12-15 Sibia Neurosciences, Inc. Protection of plants against plant pathogens
HU220236B (hu) 1992-05-23 2001-11-28 Smithkline Beecham Biologicals S.A. Hepatitis B felszíni antigént és egyéb antigéneket tartalmazó, kombinált oltóanyagok
JP3755890B2 (ja) 1992-06-25 2006-03-15 スミスクライン・ビーチャム・バイオロジカルス（ソシエテ・アノニム） アジュバント含有ワクチン組成物
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US5945275A (en) * 1994-10-18 1999-08-31 Corvas International, Inc. Nematode-extracted anticoagulant protein
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DE602004025192D1 (de) * 2003-12-05 2010-03-11 Roche Diagnostics Gmbh Rekombinante Carboxypeptidase B und ihre Aufreinigung
ATE517919T1 (de) * 2005-09-14 2011-08-15 Sanofi Aventis Deutschland Spaltung von insulinvorstufen durch eine trypsinvariante
CN101438166A (zh) 2006-03-14 2009-05-20 俄勒冈健康科学大学 产生针对结核病的免疫应答的方法
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JP4216875B2 (ja) * 2006-09-29 2009-01-28 株式会社東芝 メタノール応答性プロモーター、プロモーターと外来遺伝子を発現可能な様式で連結した融合遺伝子、ベクター、形質転換体、およびタンパク質の生産方法
DK2918598T3 (en) 2007-02-28 2019-04-29 The Govt Of U S A As Represented By The Secretary Of The Dept Of Health And Human Services Brachyury polypeptides and methods of use
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US8664183B2 (en) 2009-02-27 2014-03-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services SPANX-B polypeptides and their use
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WO2013152352A1 (en) 2012-04-06 2013-10-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic Live, attenuated rubella vector to express vaccine antigens
EP2895191B1 (en) 2012-09-14 2019-06-05 The U.S.A. as represented by the Secretary, Department of Health and Human Services Brachyury protein, adenoviral vectors encoding brachyury protein, and their use
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WO2017024000A1 (en) 2015-08-03 2017-02-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Brachyury deletion mutants, non-yeast vectors encoding brachyury deletion mutants, and their use

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FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
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KR850001534A (ko) * 1983-08-22 1985-03-30 제임스 에프. 나우톤 형질전환된 효모로 부터 유도된 면역원성 HBsAg
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Also Published As

Publication number Publication date
US4895800A (en) 1990-01-23
DK565186A (da) 1987-05-27
NO864704D0 (no) 1986-11-25
IN166428B (pt) 1990-05-05
ZA868601B (en) 1987-06-24
DE3688831T2 (de) 1993-11-25
ES2058055T3 (es) 1994-11-01
EP0226846B1 (en) 1993-08-04
AU583683B2 (en) 1989-05-04
PT83819B (pt) 1988-10-14
DK565186D0 (da) 1986-11-25
YU46031B (sh) 1992-12-21
YU201386A (en) 1988-10-31
KR870005099A (ko) 1987-06-04
IL80754A (en) 1993-03-15
ATE92527T1 (de) 1993-08-15
TW215457B (pt) 1993-11-01
PH25539A (en) 1991-07-24
IL80754A0 (en) 1987-02-27
MX4334A (es) 1993-12-01
CN86107885A (zh) 1987-09-23
PL152882B1 (en) 1991-02-28
JPH0763372B2 (ja) 1995-07-12
NO176025C (no) 1995-01-18
IE64519B1 (en) 1995-08-09
AU6538486A (en) 1987-05-28
JPS62190085A (ja) 1987-08-20
FI95929B (fi) 1995-12-29
FI95929C (fi) 1996-04-10
PL262598A1 (en) 1987-09-21
FI864791A (fi) 1987-05-27
FI864791A0 (fi) 1986-11-25
KR920004050B1 (ko) 1992-05-23
HUT43112A (en) 1987-09-28
DD252614A5 (de) 1987-12-23
PH25941A (en) 1991-12-19
EP0226846A1 (en) 1987-07-01
PT83819A (en) 1986-12-01
NO176025B (no) 1994-10-10
CA1285895C (en) 1991-07-09
CS864186A3 (en) 1992-01-15
IE863021L (en) 1987-05-26
DE3688831D1 (de) 1993-09-09
NZ218286A (en) 1991-07-26
CS276453B6 (en) 1992-06-17

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