DD248592A5 - Verfahren zur herstellung der [3s(z)]-2-[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfoxy)-3-azetidinyl]-amino]-2-oxoaethyliden]-aminooxyessigsaeure und ihrer salze - Google Patents

Verfahren zur herstellung der [3s(z)]-2-[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfoxy)-3-azetidinyl]-amino]-2-oxoaethyliden]-aminooxyessigsaeure und ihrer salze Download PDF

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Publication number
DD248592A5
DD248592A5 DD86292942A DD29294286A DD248592A5 DD 248592 A5 DD248592 A5 DD 248592A5 DD 86292942 A DD86292942 A DD 86292942A DD 29294286 A DD29294286 A DD 29294286A DD 248592 A5 DD248592 A5 DD 248592A5
Authority
DD
German Democratic Republic
Prior art keywords
amino
oxo
azetidinyl
dimethyl
thiazolyl
Prior art date
Application number
DD86292942A
Other languages
German (de)
English (en)
Inventor
William A Slusarchyk
Tamara Dejneka
William H Koster
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �K@�K@������@���@����K@���Kk�� filed Critical �K@�K@������@���@����K@���Kk��
Publication of DD248592A5 publication Critical patent/DD248592A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/18—Salts thereof

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DD86292942A 1985-01-28 1986-01-28 Verfahren zur herstellung der [3s(z)]-2-[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfoxy)-3-azetidinyl]-amino]-2-oxoaethyliden]-aminooxyessigsaeure und ihrer salze DD248592A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/695,775 US4638061A (en) 1985-01-28 1985-01-28 [3S(Z)]-2-[[[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]-amino]oxy] acetic acid and intermediate

Publications (1)

Publication Number Publication Date
DD248592A5 true DD248592A5 (de) 1987-08-12

Family

ID=24794413

Family Applications (3)

Application Number Title Priority Date Filing Date
DD86292942A DD248592A5 (de) 1985-01-28 1986-01-28 Verfahren zur herstellung der [3s(z)]-2-[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfoxy)-3-azetidinyl]-amino]-2-oxoaethyliden]-aminooxyessigsaeure und ihrer salze
DD86286545A DD241600A5 (de) 1985-01-28 1986-01-28 Verfahren zur herstellung von 4,4-dialkyl-2-azetidinon-verbindungen
DD86292943A DD248584A5 (de) 1985-01-28 1986-01-28 Verfahren zur herstellung von (3s)-3-amino-2-oxo-4,4-dimethyl-1-azetidinylsulfat und seinen salzen mit basen

Family Applications After (2)

Application Number Title Priority Date Filing Date
DD86286545A DD241600A5 (de) 1985-01-28 1986-01-28 Verfahren zur herstellung von 4,4-dialkyl-2-azetidinon-verbindungen
DD86292943A DD248584A5 (de) 1985-01-28 1986-01-28 Verfahren zur herstellung von (3s)-3-amino-2-oxo-4,4-dimethyl-1-azetidinylsulfat und seinen salzen mit basen

Country Status (35)

Country Link
US (1) US4638061A (fr)
JP (2) JPH0780840B2 (fr)
KR (1) KR900000675B1 (fr)
CN (1) CN1014894B (fr)
AR (1) AR242024A1 (fr)
AT (1) AT389511B (fr)
AU (1) AU588017B2 (fr)
BE (1) BE904121A (fr)
CA (2) CA1283924C (fr)
CH (3) CH670825A5 (fr)
CS (1) CS253740B2 (fr)
DD (3) DD248592A5 (fr)
DE (1) DE3602347A1 (fr)
DK (1) DK39486A (fr)
EG (1) EG17682A (fr)
ES (3) ES8706112A1 (fr)
FI (1) FI85022C (fr)
FR (1) FR2576596B1 (fr)
GB (2) GB2170201B (fr)
GR (1) GR860239B (fr)
HU (1) HU196367B (fr)
IE (2) IE930750L (fr)
IL (1) IL77661A (fr)
IT (1) IT1190604B (fr)
LU (1) LU86262A1 (fr)
NL (1) NL8600136A (fr)
NO (1) NO170014C (fr)
NZ (1) NZ214836A (fr)
PH (3) PH22425A (fr)
PL (3) PL262318A1 (fr)
PT (1) PT81914B (fr)
RO (1) RO93483B (fr)
SE (3) SE467824B (fr)
YU (2) YU45760B (fr)
ZA (1) ZA86302B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751220A (en) * 1986-12-19 1988-06-14 E. R. Squibb & Sons, Inc. Crystalline salts of [3S(Z)]-2[[[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]-amino]oxy]acetic acid
EP0336667A3 (fr) * 1988-04-04 1991-04-10 E.R. Squibb & Sons, Inc. Sulfate de [3S(Z)]-3-[[(2-amino-4-thiazolyl)[[2-(hydroxyamino)-2-oxoéthoxy]imino]acétyl]-amino]-2,2-diméthyl-4-oxo-1-azétidine
US5143913A (en) * 1988-04-04 1992-09-01 E. R. Squibb & Sons, Inc. [3S(Z)]-3-[[(2-amino-4-thiazolyl)[[2-(hydroxyamino)-2-oxoethoxy]imino]acetyl]amino]-2,2-dimethyl-4-oxo-1-azetidinyl sulfate
US4973747A (en) * 1989-08-15 1990-11-27 E. R. Squibb & Sons, Inc. Process for preparing 3-hydroxy 2-keto acids
PL1965798T3 (pl) * 2005-12-07 2012-02-29 Basilea Pharmaceutica Ag Użyteczne antybiotyki monobaktamowe
WO2017180794A1 (fr) 2016-04-13 2017-10-19 Skyline Antiinfectives, Inc. Acides hydroxamiques de bêta-lactame o-sulfatés deutérés et bêta-lactames n-sulfatés deutérés

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4337197A (en) * 1980-10-31 1982-06-29 E. R. Squibb & Sons, Inc. O-sulfated β-lactam hydroxamic acids and intermediates
JPS58113174A (ja) * 1981-12-26 1983-07-05 Toyama Chem Co Ltd 新規なアゼチジン誘導体またはその塩類を含有する抗菌剤
JPS58194856A (ja) * 1982-05-10 1983-11-12 Yamanouchi Pharmaceut Co Ltd 新規２−アゼチジノン誘導体
JPS58206589A (ja) * 1982-05-26 1983-12-01 Yamanouchi Pharmaceut Co Ltd ２−アゼチジノン誘導体
US4565654A (en) * 1983-03-28 1986-01-21 University Of Notre Dame Du Lac N-Acyloxy monocyclic β-lactams

Also Published As

Publication number Publication date
GB2170201A (en) 1986-07-30
HUT40407A (en) 1986-12-28
FR2576596A1 (fr) 1986-08-01
AU588017B2 (en) 1989-09-07
ES551252A0 (es) 1987-06-01
ZA86302B (en) 1986-08-27
RO93483A (fr) 1987-12-31
YU167087A (en) 1988-04-30
BE904121A (fr) 1986-05-15
GB2198133B (en) 1989-01-11
CA1279322C (fr) 1991-01-22
SE9002338D0 (sv) 1990-07-03
SE8600355D0 (sv) 1986-01-27
LU86262A1 (fr) 1986-08-04
PL149156B1 (en) 1990-01-31
HU196367B (en) 1988-11-28
SE502442C2 (sv) 1995-10-16
ATA20386A (de) 1989-05-15
SE467824B (sv) 1992-09-21
DK39486D0 (da) 1986-01-27
CH667872A5 (fr) 1988-11-15
IE860205L (en) 1986-07-28
GB2170201B (en) 1989-01-11
DD248584A5 (de) 1987-08-12
KR900000675B1 (ko) 1990-02-02
DK39486A (da) 1986-07-29
NL8600136A (nl) 1986-08-18
PL262317A1 (en) 1987-09-07
RO93483B (ro) 1988-01-01
IT8619206A0 (it) 1986-01-28
YU45760B (sh) 1992-07-20
PL262318A1 (en) 1987-09-07
ES557056A0 (es) 1987-12-01
PH23084A (en) 1989-04-10
FI860247A (fi) 1986-07-29
SE9002338L (sv) 1990-07-03
SE468896B (sv) 1993-04-05
IE59629B1 (en) 1994-03-09
AT389511B (de) 1989-12-27
JPS61176563A (ja) 1986-08-08
NO170014B (no) 1992-05-25
YU5886A (en) 1988-02-29
CS253740B2 (en) 1987-12-17
DE3602347A1 (de) 1986-07-31
KR860005812A (ko) 1986-08-13
PT81914A (en) 1986-02-01
US4638061A (en) 1987-01-20
ES8800897A1 (es) 1987-12-01
FI85022B (fi) 1991-11-15
IL77661A (en) 1989-06-30
SE8600355L (sv) 1986-07-29
DD241600A5 (de) 1986-12-17
FR2576596B1 (fr) 1989-12-15
GR860239B (en) 1986-05-28
NO860273L (no) 1986-07-29
PL257668A1 (en) 1987-03-09
EG17682A (en) 1990-10-30
CN86100736A (zh) 1986-10-22
GB8800425D0 (en) 1988-02-10
NO170014C (no) 1992-09-02
NZ214836A (en) 1988-10-28
ES8706112A1 (es) 1987-06-01
SE9002337L (sv) 1990-07-03
FI85022C (fi) 1992-02-25
ES8801917A1 (es) 1988-03-01
CN1014894B (zh) 1991-11-27
AU5246086A (en) 1986-07-31
CH670825A5 (fr) 1989-07-14
ES557057A0 (es) 1988-03-01
JPH0780840B2 (ja) 1995-08-30
SE9002337D0 (sv) 1990-07-03
GB2198133A (en) 1988-06-08
JPH0853404A (ja) 1996-02-27
CA1283924C (fr) 1991-05-07
PT81914B (pt) 1987-11-30
FI860247A0 (fi) 1986-01-20
AR242024A1 (es) 1993-02-26
IE930750L (en) 1986-07-28
IT1190604B (it) 1988-02-16
PH22425A (en) 1988-09-12
CH670824A5 (fr) 1989-07-14
PH23093A (en) 1989-04-10

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