DD151408A5 - Verfahren zur herstellung neuer pharmazeutisch aktiver phenylpiperazinderivate - Google Patents

Verfahren zur herstellung neuer pharmazeutisch aktiver phenylpiperazinderivate Download PDF

Info

Publication number
DD151408A5
DD151408A5 DD80219413A DD21941380A DD151408A5 DD 151408 A5 DD151408 A5 DD 151408A5 DD 80219413 A DD80219413 A DD 80219413A DD 21941380 A DD21941380 A DD 21941380A DD 151408 A5 DD151408 A5 DD 151408A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
compound
item
point
meaning given
Prior art date
Application number
DD80219413A
Other languages
German (de)
English (en)
Inventor
Hans H Haeck
Feddo C Hillen
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of DD151408A5 publication Critical patent/DD151408A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Cookers (AREA)
DD80219413A 1979-03-01 1980-03-03 Verfahren zur herstellung neuer pharmazeutisch aktiver phenylpiperazinderivate DD151408A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7901633 1979-03-01

Publications (1)

Publication Number Publication Date
DD151408A5 true DD151408A5 (de) 1981-10-21

Family

ID=19832723

Family Applications (1)

Application Number Title Priority Date Filing Date
DD80219413A DD151408A5 (de) 1979-03-01 1980-03-03 Verfahren zur herstellung neuer pharmazeutisch aktiver phenylpiperazinderivate

Country Status (20)

Country Link
EP (1) EP0015615B1 (es)
JP (1) JPS55141478A (es)
AT (1) ATE2219T1 (es)
AU (1) AU532411B2 (es)
CA (1) CA1138461A (es)
CS (1) CS216525B2 (es)
DD (1) DD151408A5 (es)
DE (1) DE3061561D1 (es)
DK (1) DK84380A (es)
ES (3) ES8106898A1 (es)
FI (1) FI800588A (es)
GR (1) GR67005B (es)
HU (1) HU182070B (es)
IE (1) IE49526B1 (es)
IL (1) IL59489A (es)
PH (1) PH17025A (es)
PL (1) PL126161B1 (es)
SU (1) SU1039442A3 (es)
YU (1) YU54680A (es)
ZA (1) ZA801119B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8005133A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met antiagressieve werking.
NL8005131A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met analgetische werking.
US4457931A (en) * 1982-09-27 1984-07-03 Selvi & C. S.P.A. Piperazine derivatives with anticholinergic and/or antihistaminic activity
JPH0660160B2 (ja) * 1985-12-13 1994-08-10 テルモ株式会社 アミド誘導体およびこれを含有する抗アレルギ−剤
CA2015033C (en) * 1989-04-22 2000-06-06 American Home Products Corporation Tertiary alkyl functionalized piperazine derivatives
GB2230781B (en) * 1989-04-22 1993-04-28 Wyeth John & Brother Ltd Piperazine derivatives
US5340812A (en) * 1989-04-22 1994-08-23 John Wyeth & Brother, Limited Piperazine derivatives
US5382583A (en) * 1989-04-22 1995-01-17 John Wyeth & Brother, Limited Piperazine derivatives
DK203990D0 (da) * 1990-08-24 1990-08-24 Novo Nordisk As Piperazinylderivater
GB9200293D0 (en) * 1992-01-08 1992-02-26 Wyeth John & Brother Ltd Piperazine derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2722529A (en) * 1955-11-01 Amides of certain l-amevoalkyl-x-phenyl
US2833770A (en) * 1958-05-06 Chj-chj
BE788280A (fr) * 1971-09-04 1973-02-28 Pfizer Nouvelles 1-(3-trifluoro-methyl-phenyl)-4-((amido cyclique)- alkyl) piperazines et composition pharmaceutique les contenant
GB1443598A (en) * 1973-07-06 1976-07-21 Acraf 1- 3-acetylaminopropyl-4-2,5-dichlorophenyl-piperazine
FR2306694A1 (fr) * 1975-04-07 1976-11-05 Parcor Derives de la piperazine

Also Published As

Publication number Publication date
IE49526B1 (en) 1985-10-16
YU54680A (en) 1983-09-30
CS216525B2 (en) 1982-11-26
ES8200884A1 (es) 1981-11-16
AU532411B2 (en) 1983-09-29
AU5584880A (en) 1980-09-04
PL222294A1 (es) 1980-12-01
PH17025A (en) 1984-05-17
GR67005B (es) 1981-05-18
ES488988A0 (es) 1981-09-01
HU182070B (en) 1983-12-28
ES8200883A1 (es) 1981-11-16
ZA801119B (en) 1981-09-30
ES495106A0 (es) 1981-11-16
IE800405L (en) 1980-09-01
IL59489A (en) 1984-05-31
EP0015615B1 (en) 1983-01-12
EP0015615A1 (en) 1980-09-17
PL126161B1 (en) 1983-07-30
ES495105A0 (es) 1981-11-16
SU1039442A3 (ru) 1983-08-30
ATE2219T1 (de) 1983-01-15
CA1138461A (en) 1982-12-28
DE3061561D1 (en) 1983-02-17
FI800588A (fi) 1980-09-02
JPS55141478A (en) 1980-11-05
DK84380A (da) 1980-09-02
IL59489A0 (en) 1980-05-30
ES8106898A1 (es) 1981-09-01

Similar Documents

Publication Publication Date Title
DE1695556C3 (de) 3-Alkyl-1,2,3,4,4a,9-hexahydropyrazino[1,2-f]morphanthridinderivate
EP0136658B1 (de) 1-Benzyl-aminoalkyl-pyrrolidinone und ihre Säureadditionssalze, Verfahren zu ihrer Herstellung und Arzneimittel
DE2503815C2 (de) Indazol-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel
DE2205815A1 (de) Piperazinderivate und verfahren zu ihrer herstellung
DE3212304A1 (de) Imidazolylphenyl-tetrahydropyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
EP0163260B1 (de) Neue substituierte Pyrrolidinone, Verfahren zu ihrer Herstellung und Arzneimittel
DD151408A5 (de) Verfahren zur herstellung neuer pharmazeutisch aktiver phenylpiperazinderivate
CH643809A5 (de) Aminoalkohol-derivate.
DE3334757A1 (de) Piperazinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate
DE1518452B2 (de) 4-substituierte 2-benzhydryl-2butanol-derivate und verfahren zu ihrer herstellung
CH558784A (de) Verfahren zur herstellung von sulfonaniliden.
DD151933A5 (de) Verfahren zur herstellung von basischen oximaethern
DE1905353C3 (de) 2-Benzylimidazolinderivate, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen
DE3305495A1 (de) Piperazin- und homopiperazinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen
DE2609437C2 (es)
DE2628464C2 (de) Xanthen-9-carbonsäureester, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende pharmazeutische Mittel
DE2833892C2 (de) 12H-Dibenzo[d,g][1,3,6]dioxazocinderivate, solche enthaltende Arzneimittel und Verfahren zur Herstellung derselben
DE2609862C2 (es)
DE1076691B (de) Verfahren zur Herstellung von Phenthiazinderivaten
DE1620373A1 (de) Verfahren zur Herstellung von neuen heterocyclischen Verbindungen
DD202288A5 (de) Verfahren zur herstellung von phenylpiperazinderivaten
DE1670143C3 (es)
AT375079B (de) Verfahren zur herstellung von neuen trans-2,3,4,4a ,5,9b-hexahydro-1h-pyrido(4,3-b)indolen und ihren pharmazeutisch annehmbaren salzen
DE1018868B (de) Verfahren zur Herstellung von Phenthiazinderivaten
DE3121137A1 (de) Neue pyridazino(4,5-b)indole, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen, zwischenprodukte und deren herstellung"