CS216525B2 - Method of making the phenylpiperazine derivatives - Google Patents

Method of making the phenylpiperazine derivatives Download PDF

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Publication number
CS216525B2
CS216525B2 CS801368A CS136880A CS216525B2 CS 216525 B2 CS216525 B2 CS 216525B2 CS 801368 A CS801368 A CS 801368A CS 136880 A CS136880 A CS 136880A CS 216525 B2 CS216525 B2 CS 216525B2
Authority
CS
Czechoslovakia
Prior art keywords
compound
group
compounds
formula
piperazine
Prior art date
Application number
CS801368A
Other languages
Czech (cs)
English (en)
Inventor
Hans W Haeck
Feddo C Hillen
International Research Duphar
Original Assignee
Hans W Haeck
Feddo C Hillen
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hans W Haeck, Feddo C Hillen, Duphar Int Res filed Critical Hans W Haeck
Publication of CS216525B2 publication Critical patent/CS216525B2/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Cookers (AREA)
CS801368A 1979-03-01 1980-02-28 Method of making the phenylpiperazine derivatives CS216525B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7901633 1979-03-01

Publications (1)

Publication Number Publication Date
CS216525B2 true CS216525B2 (en) 1982-11-26

Family

ID=19832723

Family Applications (1)

Application Number Title Priority Date Filing Date
CS801368A CS216525B2 (en) 1979-03-01 1980-02-28 Method of making the phenylpiperazine derivatives

Country Status (20)

Country Link
EP (1) EP0015615B1 (es)
JP (1) JPS55141478A (es)
AT (1) ATE2219T1 (es)
AU (1) AU532411B2 (es)
CA (1) CA1138461A (es)
CS (1) CS216525B2 (es)
DD (1) DD151408A5 (es)
DE (1) DE3061561D1 (es)
DK (1) DK84380A (es)
ES (3) ES8106898A1 (es)
FI (1) FI800588A (es)
GR (1) GR67005B (es)
HU (1) HU182070B (es)
IE (1) IE49526B1 (es)
IL (1) IL59489A (es)
PH (1) PH17025A (es)
PL (1) PL126161B1 (es)
SU (1) SU1039442A3 (es)
YU (1) YU54680A (es)
ZA (1) ZA801119B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8005133A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met antiagressieve werking.
NL8005131A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met analgetische werking.
US4457931A (en) * 1982-09-27 1984-07-03 Selvi & C. S.P.A. Piperazine derivatives with anticholinergic and/or antihistaminic activity
JPH0660160B2 (ja) * 1985-12-13 1994-08-10 テルモ株式会社 アミド誘導体およびこれを含有する抗アレルギ−剤
US5340812A (en) * 1989-04-22 1994-08-23 John Wyeth & Brother, Limited Piperazine derivatives
DK0395313T3 (da) * 1989-04-22 2000-06-19 American Home Prod Tertiære alkyl-funktionaliserede piperazin-derivater
US5382583A (en) * 1989-04-22 1995-01-17 John Wyeth & Brother, Limited Piperazine derivatives
FI102175B1 (fi) * 1989-04-22 1998-10-30 Wyeth John & Brother Ltd Menetelmä terapeuttisesti käyttökelpoisten piperatsiinijohdannaisten valmistamiseksi
DK203990D0 (da) * 1990-08-24 1990-08-24 Novo Nordisk As Piperazinylderivater
GB9200293D0 (en) * 1992-01-08 1992-02-26 Wyeth John & Brother Ltd Piperazine derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2833770A (en) * 1958-05-06 Chj-chj
US2722529A (en) * 1955-11-01 Amides of certain l-amevoalkyl-x-phenyl
BE788280A (fr) * 1971-09-04 1973-02-28 Pfizer Nouvelles 1-(3-trifluoro-methyl-phenyl)-4-((amido cyclique)- alkyl) piperazines et composition pharmaceutique les contenant
GB1443598A (en) * 1973-07-06 1976-07-21 Acraf 1- 3-acetylaminopropyl-4-2,5-dichlorophenyl-piperazine
FR2306694A1 (fr) * 1975-04-07 1976-11-05 Parcor Derives de la piperazine

Also Published As

Publication number Publication date
IE49526B1 (en) 1985-10-16
AU532411B2 (en) 1983-09-29
JPS55141478A (en) 1980-11-05
ES488988A0 (es) 1981-09-01
ATE2219T1 (de) 1983-01-15
EP0015615B1 (en) 1983-01-12
ES8200883A1 (es) 1981-11-16
SU1039442A3 (ru) 1983-08-30
AU5584880A (en) 1980-09-04
CA1138461A (en) 1982-12-28
IL59489A0 (en) 1980-05-30
PH17025A (en) 1984-05-17
EP0015615A1 (en) 1980-09-17
GR67005B (es) 1981-05-18
FI800588A (fi) 1980-09-02
ES8106898A1 (es) 1981-09-01
ES8200884A1 (es) 1981-11-16
PL222294A1 (es) 1980-12-01
DD151408A5 (de) 1981-10-21
IE800405L (en) 1980-09-01
YU54680A (en) 1983-09-30
ES495105A0 (es) 1981-11-16
DK84380A (da) 1980-09-02
DE3061561D1 (en) 1983-02-17
PL126161B1 (en) 1983-07-30
HU182070B (en) 1983-12-28
ZA801119B (en) 1981-09-30
ES495106A0 (es) 1981-11-16
IL59489A (en) 1984-05-31

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