ZA801119B - Phenyl piperazine derivatives having antiagressive activity - Google Patents

Phenyl piperazine derivatives having antiagressive activity

Info

Publication number
ZA801119B
ZA801119B ZA00801119A ZA801119A ZA801119B ZA 801119 B ZA801119 B ZA 801119B ZA 00801119 A ZA00801119 A ZA 00801119A ZA 801119 A ZA801119 A ZA 801119A ZA 801119 B ZA801119 B ZA 801119B
Authority
ZA
South Africa
Prior art keywords
compounds
piperazine derivatives
phenyl piperazine
antiagressive
activity
Prior art date
Application number
ZA00801119A
Other languages
English (en)
Inventor
F Hillen
H Haeck
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of ZA801119B publication Critical patent/ZA801119B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Cookers (AREA)
ZA00801119A 1979-03-01 1980-02-27 Phenyl piperazine derivatives having antiagressive activity ZA801119B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7901633 1979-03-01

Publications (1)

Publication Number Publication Date
ZA801119B true ZA801119B (en) 1981-09-30

Family

ID=19832723

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00801119A ZA801119B (en) 1979-03-01 1980-02-27 Phenyl piperazine derivatives having antiagressive activity

Country Status (20)

Country Link
EP (1) EP0015615B1 (xx)
JP (1) JPS55141478A (xx)
AT (1) ATE2219T1 (xx)
AU (1) AU532411B2 (xx)
CA (1) CA1138461A (xx)
CS (1) CS216525B2 (xx)
DD (1) DD151408A5 (xx)
DE (1) DE3061561D1 (xx)
DK (1) DK84380A (xx)
ES (3) ES8106898A1 (xx)
FI (1) FI800588A (xx)
GR (1) GR67005B (xx)
HU (1) HU182070B (xx)
IE (1) IE49526B1 (xx)
IL (1) IL59489A (xx)
PH (1) PH17025A (xx)
PL (1) PL126161B1 (xx)
SU (1) SU1039442A3 (xx)
YU (1) YU54680A (xx)
ZA (1) ZA801119B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8005133A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met antiagressieve werking.
NL8005131A (nl) * 1980-09-12 1982-04-01 Duphar Int Res Fenylpiperazinederivaten met analgetische werking.
US4457931A (en) * 1982-09-27 1984-07-03 Selvi & C. S.P.A. Piperazine derivatives with anticholinergic and/or antihistaminic activity
JPH0660160B2 (ja) * 1985-12-13 1994-08-10 テルモ株式会社 アミド誘導体およびこれを含有する抗アレルギ−剤
US5340812A (en) * 1989-04-22 1994-08-23 John Wyeth & Brother, Limited Piperazine derivatives
DK0395313T3 (da) * 1989-04-22 2000-06-19 American Home Prod Tertiære alkyl-funktionaliserede piperazin-derivater
US5382583A (en) * 1989-04-22 1995-01-17 John Wyeth & Brother, Limited Piperazine derivatives
FI102175B1 (fi) * 1989-04-22 1998-10-30 Wyeth John & Brother Ltd Menetelmä terapeuttisesti käyttökelpoisten piperatsiinijohdannaisten valmistamiseksi
DK203990D0 (da) * 1990-08-24 1990-08-24 Novo Nordisk As Piperazinylderivater
GB9200293D0 (en) * 1992-01-08 1992-02-26 Wyeth John & Brother Ltd Piperazine derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2833770A (en) * 1958-05-06 Chj-chj
US2722529A (en) * 1955-11-01 Amides of certain l-amevoalkyl-x-phenyl
BE788280A (fr) * 1971-09-04 1973-02-28 Pfizer Nouvelles 1-(3-trifluoro-methyl-phenyl)-4-((amido cyclique)- alkyl) piperazines et composition pharmaceutique les contenant
GB1443598A (en) * 1973-07-06 1976-07-21 Acraf 1- 3-acetylaminopropyl-4-2,5-dichlorophenyl-piperazine
FR2306694A1 (fr) * 1975-04-07 1976-11-05 Parcor Derives de la piperazine

Also Published As

Publication number Publication date
IE49526B1 (en) 1985-10-16
AU532411B2 (en) 1983-09-29
JPS55141478A (en) 1980-11-05
ES488988A0 (es) 1981-09-01
ATE2219T1 (de) 1983-01-15
EP0015615B1 (en) 1983-01-12
ES8200883A1 (es) 1981-11-16
SU1039442A3 (ru) 1983-08-30
CS216525B2 (en) 1982-11-26
AU5584880A (en) 1980-09-04
CA1138461A (en) 1982-12-28
IL59489A0 (en) 1980-05-30
PH17025A (en) 1984-05-17
EP0015615A1 (en) 1980-09-17
GR67005B (xx) 1981-05-18
FI800588A (fi) 1980-09-02
ES8106898A1 (es) 1981-09-01
ES8200884A1 (es) 1981-11-16
PL222294A1 (xx) 1980-12-01
DD151408A5 (de) 1981-10-21
IE800405L (en) 1980-09-01
YU54680A (en) 1983-09-30
ES495105A0 (es) 1981-11-16
DK84380A (da) 1980-09-02
DE3061561D1 (en) 1983-02-17
PL126161B1 (en) 1983-07-30
HU182070B (en) 1983-12-28
ES495106A0 (es) 1981-11-16
IL59489A (en) 1984-05-31

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