DD151309A5 - Verfahren zur herstellung von substituierten aminotriazinen - Google Patents

Verfahren zur herstellung von substituierten aminotriazinen Download PDF

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Publication number
DD151309A5
DD151309A5 DD80221474A DD22147480A DD151309A5 DD 151309 A5 DD151309 A5 DD 151309A5 DD 80221474 A DD80221474 A DD 80221474A DD 22147480 A DD22147480 A DD 22147480A DD 151309 A5 DD151309 A5 DD 151309A5
Authority
DD
German Democratic Republic
Prior art keywords
hydrogen
group
triazine
diamino
trifluoromethyl
Prior art date
Application number
DD80221474A
Other languages
German (de)
English (en)
Inventor
Martin G Baxter
Albert R Elphick
Alistair A Miller
David A Sawyer
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10505597&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DD151309(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DD151309A5 publication Critical patent/DD151309A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
DD80221474A 1979-06-01 1980-05-30 Verfahren zur herstellung von substituierten aminotriazinen DD151309A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7919257 1979-06-01

Publications (1)

Publication Number Publication Date
DD151309A5 true DD151309A5 (de) 1981-10-14

Family

ID=10505597

Family Applications (1)

Application Number Title Priority Date Filing Date
DD80221474A DD151309A5 (de) 1979-06-01 1980-05-30 Verfahren zur herstellung von substituierten aminotriazinen

Country Status (30)

Country Link
US (2) US4486354A (da)
EP (2) EP0059987B1 (da)
JP (2) JPS5625169A (da)
AR (1) AR227521A1 (da)
AT (1) AT370097B (da)
AU (2) AU530999B2 (da)
BG (1) BG60427B2 (da)
CA (1) CA1112643A (da)
CS (1) CS234018B2 (da)
CZ (1) CZ384891A3 (da)
DD (1) DD151309A5 (da)
DK (1) DK153787C (da)
ES (1) ES8104993A1 (da)
FI (1) FI67844C (da)
GE (1) GEP19960470B (da)
GR (1) GR68380B (da)
HU (1) HU182086B (da)
IE (1) IE49823B1 (da)
IL (1) IL60201A (da)
IT (1) IT1147087B (da)
MX (1) MX9202962A (da)
MY (1) MY8500062A (da)
NL (1) NL950007I2 (da)
NZ (1) NZ193890A (da)
PL (1) PL124029B1 (da)
SU (1) SU1055331A3 (da)
UA (1) UA5576A1 (da)
YU (1) YU145680A (da)
ZA (1) ZA803250B (da)
ZW (1) ZW12980A1 (da)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
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GB9305692D0 (en) * 1993-03-19 1993-05-05 Wellcome Found Therapeutic triazine compounds and use
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GB9426448D0 (en) * 1994-12-30 1995-03-01 Wellcome Found Process
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GB2395483A (en) * 2003-07-03 2004-05-26 Jubilant Organosys Ltd Crystalline lamotrigine and its monohydrate
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CN101312952B (zh) 2005-09-23 2012-12-26 詹森药业有限公司 四氢-环戊二烯并吡唑大麻素调节剂
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ES2858750T3 (es) * 2015-06-12 2021-09-30 Univ Greenwich Derivados de triazina como inhibidores del interferón gamma
JP6931701B2 (ja) 2016-12-16 2021-09-08 イドーシア ファーマシューティカルズ リミテッドＩｄｏｒｓｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ Ｔ型カルシウムチャンネルブロッカーを含有する薬学的合剤
TWI826531B (zh) 2018-09-21 2023-12-21 南韓商愛思開生物製藥股份有限公司 具有㗁二唑之化合物及包含該化合物之醫藥組合物

Family Cites Families (8)

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GB759014A (en) * 1952-02-26 1956-10-10 Wellcome Found Improvements in triazines and their manufacture
AT190941B (de) * 1954-09-22 1957-07-25 Chemie Linz Ag Verfahren zur Herstellung neuer Guanylhydrazone
US2952677A (en) * 1956-10-01 1960-09-13 Ici Ltd Aminoguanadine compounds
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US3637688A (en) * 1970-01-09 1972-01-25 American Home Prod 6-(fluoro and trifluoromethyl phenyl)-3 5-diamino - 1 2 4 - triazines and substituted - 6 - phenylalkyl-3,5-diamino-1 2 4-triazines
EP0086502B1 (en) * 1979-08-16 1987-03-25 The Wellcome Foundation Limited Substituted aromatic triazines

Also Published As

Publication number Publication date
ES491998A0 (es) 1981-05-16
NL950007I2 (nl) 1997-02-03
GR68380B (da) 1981-12-28
BG60427B2 (bg) 1995-03-31
CZ384891A3 (en) 1993-10-13
MX9202962A (es) 1992-07-01
GEP19960470B (en) 1996-08-29
JPH0144179B2 (da) 1989-09-26
SU1055331A3 (ru) 1983-11-15
IT8048848A0 (it) 1980-05-30
US4486354A (en) 1984-12-04
IT1147087B (it) 1986-11-19
PL224633A1 (da) 1981-02-13
JPS5625169A (en) 1981-03-10
US4602017A (en) 1986-07-22
FI801758A (fi) 1980-12-02
NL950007I1 (nl) 1995-06-16
FI67844C (fi) 1985-06-10
ES8104993A1 (es) 1981-05-16
AU530999B2 (en) 1983-08-04
IL60201A0 (en) 1980-07-31
ZW12980A1 (en) 1982-01-06
IE49823B1 (en) 1985-12-25
EP0021121A1 (en) 1981-01-07
AT370097B (de) 1983-02-25
EP0059987B1 (en) 1985-08-14
DK233880A (da) 1980-12-02
AU566870B2 (en) 1987-11-05
AU5890680A (en) 1980-12-04
JPS6133163A (ja) 1986-02-17
ATA289680A (de) 1982-07-15
DK153787B (da) 1988-09-05
JPH0144706B2 (da) 1989-09-29
ZA803250B (en) 1982-01-27
IE801126L (en) 1980-12-01
FI67844B (fi) 1985-02-28
MY8500062A (en) 1985-12-31
CS234018B2 (en) 1985-03-14
HU182086B (en) 1983-12-28
PL124029B1 (en) 1982-12-31
DK153787C (da) 1989-01-16
YU145680A (en) 1983-02-28
AR227521A1 (es) 1982-11-15
EP0059987A1 (en) 1982-09-15
CA1112643A (en) 1981-11-17
IL60201A (en) 1984-05-31
NZ193890A (en) 1984-07-06
UA5576A1 (uk) 1994-12-28
EP0021121B1 (en) 1983-05-11

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