GB9718972D0
(en)
|
1996-09-25 |
1997-11-12 |
Zeneca Ltd |
Chemical compounds
|
AU733551B2
(en)
|
1996-09-25 |
2001-05-17 |
Astrazeneca Ab |
Qinoline derivatives inhibiting the effect of growth factors such as VEGF
|
CO4950519A1
(es)
*
|
1997-02-13 |
2000-09-01 |
Novartis Ag |
Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
|
EP1005470B1
(en)
|
1997-08-22 |
2007-08-01 |
AstraZeneca AB |
Oxindolylquinazoline derivatives as angiogenesis inhibitors
|
ES2342240T3
(es)
*
|
1998-08-11 |
2010-07-02 |
Novartis Ag |
Derivados de isoquinolina con actividad que inhibe la angiogenia.
|
PT1105136E
(pt)
*
|
1998-08-13 |
2007-12-03 |
Novartis Ag |
Método para tratar doenças oculares neovasculares
|
WO2000059509A1
(en)
*
|
1999-03-30 |
2000-10-12 |
Novartis Ag |
Phthalazine derivatives for treating inflammatory diseases
|
AR025068A1
(es)
*
|
1999-08-10 |
2002-11-06 |
Bayer Corp |
Pirazinas sustituidas y piridazinas fusionadas, composicion farmaceutica que las comprenden, uso de dichos compuestos para la manufactura de un medicamentocon actividad inhibidora de angiogenesis
|
US6271233B1
(en)
|
1999-08-10 |
2001-08-07 |
Ciba Vision Corporation |
Method for treating ocular neovascular diseases
|
GT200000158A
(es)
|
1999-09-28 |
2002-03-16 |
|
Piridinas y piridacinas sustituidas con actividad de inhibicion de angiogenesis.
|
US6689883B1
(en)
|
1999-09-28 |
2004-02-10 |
Bayer Pharmaceuticals Corporation |
Substituted pyridines and pyridazines with angiogenesis inhibiting activity
|
NZ518028A
(en)
|
1999-11-05 |
2004-03-26 |
Astrazeneca Ab |
Quinazoline derivatives as VEGF inhibitors
|
DE19963607B4
(de)
*
|
1999-12-23 |
2005-12-15 |
Schering Ag |
Verfahren zur Herstellung von 4-(Heteroaryl-methyl) halogen-1(2H)-phthalazinonen
|
PT1254138E
(pt)
*
|
2000-02-09 |
2005-09-30 |
Novartis Ag |
Derivados de piridina que inibem a angiogenese e/ou o receptor de tirosina cinase do vegf
|
US7087608B2
(en)
|
2000-03-03 |
2006-08-08 |
Robert Charles Atkins |
Use of PDGF receptor tyrosine kinase inhibitors for the treatment of diabetic nephropathy
|
AU779695B2
(en)
|
2000-04-07 |
2005-02-10 |
Astrazeneca Ab |
Quinazoline compounds
|
US7977333B2
(en)
|
2000-04-20 |
2011-07-12 |
Bayer Healthcare Llc |
Substituted pyridines and pyridazines with angiogenesis inhibiting activity
|
EP1166798A1
(en)
*
|
2000-06-23 |
2002-01-02 |
Schering Aktiengesellschaft |
Combinations and compositions which interfere with VEGF/VEGF and angiopoietin/ Tie receptor function and their use
|
EP1166799A1
(en)
*
|
2000-06-28 |
2002-01-02 |
Schering Aktiengesellschaft |
Combinations and compositions which interfere with VEGF/VEGF and angiopoietin/Tie receptor function and their use (II)
|
EP1292335B1
(en)
*
|
2000-06-23 |
2007-05-30 |
Bayer Schering Pharma Aktiengesellschaft |
Combinations and compositions which interfere with vegf/vegf and angiopoietin/tie receptor function and their use (ii)
|
BR0113078A
(pt)
*
|
2000-08-09 |
2003-07-01 |
Astrazeneca Ab |
Uso de um composto, composto, processo para a preparação do mesmo, composição farmacêutica, e, método para produzir um efeito antiangiogênico e/ou redutor da permeabilidade vascular em um animal de sangue quente
|
US6903101B1
(en)
|
2000-08-10 |
2005-06-07 |
Bayer Pharmaceuticals Corporation |
Substituted pyridazines and fused pyridazines with angiogenesis inhibiting activity
|
DE60134679D1
(de)
|
2000-10-20 |
2008-08-14 |
Eisai R&D Man Co Ltd |
Stickstoff enthaltende aromatische Heterozyklen
|
KR100804564B1
(ko)
*
|
2000-10-30 |
2008-02-20 |
쿠도스 파마슈티칼스 리미티드 |
프탈라지논 유도체
|
EP1810715A3
(en)
*
|
2000-11-22 |
2009-12-16 |
Novartis AG |
Combination comprising an agent decreasing VEGF activity and an agent decreasing EGF activity
|
US7814641B2
(en)
|
2001-01-09 |
2010-10-19 |
Black & Decker Inc. |
Method of forming a power tool
|
US7096566B2
(en)
*
|
2001-01-09 |
2006-08-29 |
Black & Decker Inc. |
Method for making an encapsulated coil structure
|
CZ307940B6
(cs)
|
2001-02-19 |
2019-09-04 |
Novartis Pharma Ag |
40-O-(2-hydroxyethyl)rapamycin pro použití při léčení
|
GB0111078D0
(en)
*
|
2001-05-04 |
2001-06-27 |
Novartis Ag |
Organic compounds
|
DK1392313T3
(da)
|
2001-05-16 |
2007-06-25 |
Novartis Ag |
Kombination omfattende N-{5-[4-(4-methyl-piperazino-methyl)-benzoyl-amido]-2-methylphenyl}-4-(3-pyridyl)-2-pyrimidin-amin og et biphosphonat
|
TWI315982B
(en)
|
2001-07-19 |
2009-10-21 |
Novartis Ag |
Combinations comprising epothilones and pharmaceutical uses thereof
|
US20030073692A1
(en)
|
2001-08-07 |
2003-04-17 |
Pharmacia & Upjohn S.P.A. |
Amino-phthalazinone derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them
|
SI1427420T1
(sl)
*
|
2001-09-12 |
2006-12-31 |
Novartis Ag |
Uporaba kombinacije, ki vsebuje 4-piridilmetilftalazine za zdravljenje raka
|
RU2320344C2
(ru)
*
|
2001-09-12 |
2008-03-27 |
Новартис Аг |
Применение 4-пиридилметилфталазинов для лечения рака
|
AU2002342678B2
(en)
*
|
2001-09-12 |
2006-08-24 |
Novartis Ag |
Use of 4-pyridylmethylphthalazines for cancer treatment
|
WO2003028711A2
(en)
*
|
2001-09-27 |
2003-04-10 |
Novartis Ag |
Use of c-kit inhibitors for the treatment of myeloma
|
DK1441714T3
(da)
*
|
2001-10-25 |
2008-03-31 |
Novartis Ag |
Kombinationer omfattende en selektiv cyclooxygenase-2-inhibitor
|
AU2002364102A1
(en)
*
|
2001-12-21 |
2003-07-30 |
Bayer Pharmaceuticals Corporation |
Anti-angiogenesis combination therapies comprising pyridazine or pyridine derivatives
|
EP1458713B1
(en)
|
2001-12-27 |
2005-08-24 |
Theravance, Inc. |
Indolinone derivatives useful as protein kinase inhibitors
|
US20030171375A1
(en)
*
|
2002-02-13 |
2003-09-11 |
Brazzell Romulus Kimbro |
Method for treating ocular neovascular diseases
|
GB0206215D0
(en)
|
2002-03-15 |
2002-05-01 |
Novartis Ag |
Organic compounds
|
US20050209237A1
(en)
*
|
2002-04-30 |
2005-09-22 |
Brazzell Romulus K |
Method for decreasing capillary permeability in the retina
|
KR20120125398A
(ko)
*
|
2002-05-16 |
2012-11-14 |
노파르티스 아게 |
암에서 edg 수용체 결합제의 용도
|
CA2490130A1
(en)
*
|
2002-06-28 |
2004-01-08 |
Novartis Ag |
Combination comprising a vasculostatic compound and an alkylating agent for the treatment of a tumor
|
US7195876B2
(en)
*
|
2002-08-09 |
2007-03-27 |
Theravance, Inc. |
Oncokinase fusion polypeptides associated with hyperproliferative and related disorders, nucleic acids encoding the same and methods for detecting and identifying the same
|
KR20050074450A
(ko)
*
|
2002-09-24 |
2005-07-18 |
노파르티스 아게 |
골수형성이상 증후군의 치료용 약물의 제조를 위한4-피리딜메틸-프탈라진 유도체의 용도
|
GB0223341D0
(en)
*
|
2002-10-08 |
2002-11-13 |
Groningen Acad Ziekenhuis |
Organic compounds
|
US20060148810A1
(en)
*
|
2002-10-10 |
2006-07-06 |
Frank Giles |
Treatment of amm
|
US7268137B2
(en)
*
|
2002-11-07 |
2007-09-11 |
Campochiaro Peter A |
Ocular therapy
|
US20060058313A1
(en)
*
|
2002-11-12 |
2006-03-16 |
Hohneker John A |
Treatment of mesothelioma
|
US7094785B1
(en)
|
2002-12-18 |
2006-08-22 |
Cornell Research Foundation, Inc. |
Method of treating polycythemia vera
|
EP1581228A1
(en)
*
|
2002-12-20 |
2005-10-05 |
Dana-Farber Cancer Institute, Inc. |
Treatment of von hippel lindau disease
|
JP2006514991A
(ja)
*
|
2002-12-27 |
2006-05-18 |
シエーリング アクチエンゲゼルシャフト |
新規医薬組合せ
|
EP2527326B1
(en)
|
2003-03-07 |
2014-10-08 |
Santen Pharmaceutical Co., Ltd |
Novel compounds having 4-pyridylalkylthio group as substituent
|
US20050043233A1
(en)
|
2003-04-29 |
2005-02-24 |
Boehringer Ingelheim International Gmbh |
Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis
|
US20040242886A1
(en)
*
|
2003-04-30 |
2004-12-02 |
Sandeep Gupta |
Monocyclic diazodioxide based Bcl-2 protein antagonists related applications
|
MY150088A
(en)
|
2003-05-19 |
2013-11-29 |
Irm Llc |
Immunosuppressant compounds and compositions
|
EP2644195A1
(en)
|
2003-05-19 |
2013-10-02 |
Irm Llc |
Immunosuppressant Compounds and Compositions
|
BRPI0412885A
(pt)
|
2003-07-18 |
2006-10-03 |
Amgen Inc |
polipeptìdios, agentes de ligação especìficos, moléculas de ácido nucleico e linhas de células isoladas, células hospedeiras, composições e anticorpo ou domìnio de ligação de antìgeno e métodos de tratamento de cáncer e de tumor sólido num paciente, de detecção do nìvel do fator de crescimento hepatócito (hgf) numa amostra, de obtenção de anticorpo e de inibição da ligação de hgf a met e de diminuição ou prevenção da ligação de qualquer um dos agentes de ligação especìficos ao fator de crescimento hepatócito (hgf)
|
WO2005044788A1
(ja)
|
2003-11-11 |
2005-05-19 |
Eisai Co., Ltd. |
ウレア誘導体およびその製造方法
|
EP1686997B1
(en)
|
2003-11-18 |
2009-04-15 |
Novartis AG |
Inhibitors of the mutant form of kit
|
US20050171182A1
(en)
*
|
2003-12-11 |
2005-08-04 |
Roger Briesewitz |
Methods and compositions for use in the treatment of mutant receptor tyrosine kinase driven cellular proliferative diseases
|
PL1717229T3
(pl)
|
2004-02-17 |
2011-11-30 |
Santen Pharmaceutical Co Ltd |
Nowy cykliczny związek mający grupę 4-pirydyloalkilotiolową z wprowadzoną do niej (nie)podstawioną grupą aminową
|
EP1568368A1
(en)
*
|
2004-02-26 |
2005-08-31 |
Schering Aktiengesellschaft |
Pharmaceutical combination comprising a CDK inhibitor and a VEGF receptor inhibitor
|
FR2868780B1
(fr)
*
|
2004-04-13 |
2008-10-17 |
Sanofi Synthelabo |
Derives de la 1-amino-phthalazine, leur preparation et leur application en therapeutique
|
GB0512324D0
(en)
|
2005-06-16 |
2005-07-27 |
Novartis Ag |
Organic compounds
|
EP2277595A3
(en)
|
2004-06-24 |
2011-09-28 |
Novartis Vaccines and Diagnostics, Inc. |
Compounds for immunopotentiation
|
US8772269B2
(en)
|
2004-09-13 |
2014-07-08 |
Eisai R&D Management Co., Ltd. |
Use of sulfonamide-including compounds in combination with angiogenesis inhibitors
|
WO2006030947A1
(ja)
|
2004-09-13 |
2006-03-23 |
Eisai R & D Management Co., Ltd. |
スルホンアミド含有化合物の血管新生阻害物質との併用
|
PE20060664A1
(es)
*
|
2004-09-15 |
2006-08-04 |
Novartis Ag |
Amidas biciclicas como inhibidores de cinasa
|
KR20070053205A
(ko)
|
2004-09-17 |
2007-05-23 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
의약 조성물
|
ES2325344B1
(es)
*
|
2004-11-02 |
2010-06-09 |
Univ Madrid Autonoma |
Inhibidores de angiogenesis multifuncionales y multivalentes.
|
MX2007006230A
(es)
|
2004-11-30 |
2007-07-25 |
Amgen Inc |
Quinolinas y analogos de quinazolinas y su uso como medicamentos para tratar cancer.
|
EP1854787B1
(en)
|
2005-03-03 |
2010-09-01 |
Santen Pharmaceutical Co., Ltd. |
Novel cyclic compound having quinolylalkylthio group
|
US20060216288A1
(en)
*
|
2005-03-22 |
2006-09-28 |
Amgen Inc |
Combinations for the treatment of cancer
|
EP1864977B1
(en)
|
2005-03-31 |
2015-07-29 |
Santen Pharmaceutical Co., Ltd. |
Novel cyclic compound having pyrimidinylalkylthio group
|
WO2006113172A1
(en)
*
|
2005-04-13 |
2006-10-26 |
Novartis Ag |
Use of vascular endothelial growth factor receptor inhibitors for the treatment of gastrointestinal, genitourinary, lymphoid and pulmonary cancers
|
US20080176879A1
(en)
|
2005-05-02 |
2008-07-24 |
Leila Alland |
Pyrimidylaminobenzamide Derivatives For Sytemic Mastocytosis
|
GB0510390D0
(en)
|
2005-05-20 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
EP1731154A1
(en)
*
|
2005-06-07 |
2006-12-13 |
Schering Aktiengesellschaft |
Immediate-release and high-drug-load pharmaceutical formulations of micronised (4-chlorophenyl)|4-(4-pyridylmethyl)pht halazin-1-yl| and salts thereof
|
EP1731153A1
(en)
*
|
2005-06-07 |
2006-12-13 |
Schering Aktiengesellschaft |
Immediate-release and high-drug-load pharmaceutical formulations of non-micronised (4-chlorophenyl)¬4-(4-pyridylmethyl)phthalazin-1-yl| and salts thereof
|
EP1925676A4
(en)
|
2005-08-02 |
2010-11-10 |
Eisai R&D Man Co Ltd |
TEST METHOD FOR THE EFFECT OF A VASCULARIZATION INHIBITOR
|
GB0517205D0
(en)
*
|
2005-08-22 |
2005-09-28 |
Novartis Ag |
Organic compounds
|
US7915410B2
(en)
*
|
2005-09-09 |
2011-03-29 |
Bristol-Myers Squibb Company |
Acyclic IKur inhibitors
|
AR058065A1
(es)
|
2005-09-27 |
2008-01-23 |
Novartis Ag |
Compuestos de carboxiamina y uso de los mismos.composiciones farmaceuticas.
|
UA96139C2
(uk)
|
2005-11-08 |
2011-10-10 |
Дженентек, Інк. |
Антитіло до нейропіліну-1 (nrp1)
|
CA2629245C
(en)
|
2005-11-21 |
2016-07-12 |
Novartis Ag |
Neuroendocrine tumor treatment
|
US7989461B2
(en)
|
2005-12-23 |
2011-08-02 |
Amgen Inc. |
Substituted quinazolinamine compounds for the treatment of cancer
|
US20080108664A1
(en)
|
2005-12-23 |
2008-05-08 |
Liu Belle B |
Solid-state form of AMG 706 and pharmaceutical compositions thereof
|
JO2660B1
(en)
|
2006-01-20 |
2012-06-17 |
نوفارتيس ايه جي |
Pi-3 inhibitors and methods of use
|
AR059066A1
(es)
*
|
2006-01-27 |
2008-03-12 |
Amgen Inc |
Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf)
|
US7989631B2
(en)
|
2006-02-10 |
2011-08-02 |
Amgen Inc. |
Hydrate forms of AMG706
|
PE20070978A1
(es)
*
|
2006-02-14 |
2007-11-15 |
Novartis Ag |
COMPUESTOS HETEROCICLICOS COMO INHIBIDORES DE FOSFATIDILINOSITOL 3-QUINASAS (PI3Ks)
|
KR20080108517A
(ko)
|
2006-04-05 |
2008-12-15 |
노파르티스 아게 |
암을 치료하기 위한 치료제의 조합물
|
TW200808739A
(en)
*
|
2006-04-06 |
2008-02-16 |
Novartis Vaccines & Diagnostic |
Quinazolines for PDK1 inhibition
|
US8777120B2
(en)
*
|
2006-04-15 |
2014-07-15 |
International Business Machines Corporation |
Hydronic radiant flooring heating system
|
PE20080251A1
(es)
|
2006-05-04 |
2008-04-25 |
Boehringer Ingelheim Int |
Usos de inhibidores de dpp iv
|
BRPI0711385A2
(pt)
|
2006-05-09 |
2011-11-08 |
Novartis Ag |
combinação compreendendo um quelante de ferro e um agente anti-neoplástico e seu uso
|
CN101490046A
(zh)
|
2006-05-09 |
2009-07-22 |
辉瑞产品公司 |
环烷基氨基酸衍生物及其药物组合物
|
CN101443009A
(zh)
|
2006-05-18 |
2009-05-27 |
卫材R&D管理有限公司 |
针对甲状腺癌的抗肿瘤剂
|
GB0610925D0
(en)
*
|
2006-06-02 |
2006-07-12 |
Novartis Ag |
Use of vascular endothelial growth factor receptor inhibitors for the treatment of cancer
|
GB0612721D0
(en)
|
2006-06-27 |
2006-08-09 |
Novartis Ag |
Organic compounds
|
US8217177B2
(en)
|
2006-07-14 |
2012-07-10 |
Amgen Inc. |
Fused heterocyclic derivatives and methods of use
|
PE20080403A1
(es)
|
2006-07-14 |
2008-04-25 |
Amgen Inc |
Derivados heterociclicos fusionados y metodos de uso
|
JP5238697B2
(ja)
|
2006-08-04 |
2013-07-17 |
武田薬品工業株式会社 |
縮合複素環誘導体およびその用途
|
EP2065372B1
(en)
|
2006-08-28 |
2012-11-28 |
Eisai R&D Management Co., Ltd. |
Antitumor agent for undifferentiated gastric cancer
|
MX2009003185A
(es)
|
2006-09-29 |
2009-04-03 |
Novartis Ag |
Pirazolopirimidinas como inhibidores de lipido cinasa pi3k.
|
US8883790B2
(en)
|
2006-10-12 |
2014-11-11 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
US8916552B2
(en)
|
2006-10-12 |
2014-12-23 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
AU2007338792B2
(en)
|
2006-12-20 |
2012-05-31 |
Amgen Inc. |
Substituted heterocycles and methods of use
|
EP2118069B1
(en)
|
2007-01-09 |
2014-01-01 |
Amgen Inc. |
Bis-aryl amide derivatives useful for the treatment of cancer
|
KR101445892B1
(ko)
|
2007-01-29 |
2014-09-29 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
미분화형 위암 치료용 조성물
|
WO2008093677A1
(ja)
|
2007-01-29 |
2008-08-07 |
Santen Pharmaceutical Co., Ltd. |
血管新生阻害活性を有する新規オキサジアゾール誘導体およびチアジアゾール誘導体
|
WO2008100985A2
(en)
|
2007-02-15 |
2008-08-21 |
Novartis Ag |
Combination of lbh589 with other therapeutic agents for treating cancer
|
AU2008219166B2
(en)
|
2007-02-16 |
2013-05-16 |
Amgen Inc. |
Nitrogen-containing heterocyclyl ketones and their use as c-Met inhibitors
|
WO2008150015A1
(en)
|
2007-06-05 |
2008-12-11 |
Takeda Pharmaceutical Company Limited |
Heterobicyclic compounds as kinase inhibitors
|
US20090023727A1
(en)
*
|
2007-07-05 |
2009-01-22 |
Muhammad Hashim Javaid |
Phthalazinone derivatives
|
MX2010001918A
(es)
|
2007-08-21 |
2010-03-11 |
Amgen Inc |
Proteinas enlazadas al antigeno humano de celula de cepa mcdonough de felino.
|
WO2009025358A1
(ja)
|
2007-08-23 |
2009-02-26 |
Takeda Pharmaceutical Company Limited |
複素環化合物およびその用途
|
CN101116664B
(zh)
*
|
2007-08-28 |
2010-05-19 |
山东省科学院生物研究所 |
化合物1-(4-氯苯胺基)-4-(4-甲基吡啶基)-2,3-二氮杂萘的应用
|
CA2704000C
(en)
|
2007-11-09 |
2016-12-13 |
Eisai R&D Management Co., Ltd. |
Combination of anti-angiogenic substance and anti-tumor platinum complex
|
ES2437595T3
(es)
|
2007-12-20 |
2014-01-13 |
Novartis Ag |
Derivados de tiazol usados como inhibidores de la PI 3 quinasa
|
EP2628726A1
(en)
|
2008-03-26 |
2013-08-21 |
Novartis AG |
Hydroxamate-based inhibitors of deacetylases b
|
UY32030A
(es)
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
|
CA2735562C
(en)
|
2008-08-15 |
2017-10-17 |
Boehringer Ingelheim International Gmbh |
Dpp-4 inhibitors for wound healing
|
EP2344161B1
(en)
|
2008-10-16 |
2018-12-19 |
Celator Pharmaceuticals, Inc. |
Combinations of a liposomal water-soluble camptothecin with cetuximab or bevacizumab
|
US8697874B2
(en)
|
2008-12-01 |
2014-04-15 |
Takeda Pharmaceutical Company Limited |
Heterocyclic compound and use thereof
|
JO3101B1
(ar)
|
2008-12-02 |
2017-09-20 |
Takeda Pharmaceuticals Co |
مشتقات بنزوثيازول كعوامل مضادة للسرطان
|
AU2009335887A1
(en)
|
2008-12-18 |
2011-06-30 |
Novartis Ag |
New salts
|
HRP20131106T1
(hr)
|
2008-12-18 |
2013-12-20 |
Novartis Ag |
Hemifumaratna sol od 1-[4-[1-(4-cikloheksil-3-trifluorometil-benziloksiimino)-etil]-2-etil-benzil]-azetidin-3-karboksilne kiseline
|
JP2012512884A
(ja)
|
2008-12-18 |
2012-06-07 |
ノバルティス アーゲー |
1−(4−{1−[(e)−4−シクロヘキシル−3−トリフルオロメチル−ベンジルオキシイミノ]−エチル}−2−エチル−ベンジル)−アゼチジン−3−カルボン酸の新規の多形相
|
NZ592924A
(en)
|
2008-12-23 |
2014-05-30 |
Boehringer Ingelheim Int |
Salt forms of a xanthine derivative
|
TW201036975A
(en)
|
2009-01-07 |
2010-10-16 |
Boehringer Ingelheim Int |
Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy
|
PT2391366E
(pt)
|
2009-01-29 |
2013-02-05 |
Novartis Ag |
Benzimidazoles substituídos para o tratamento de astrocitomas
|
TWI466672B
(zh)
|
2009-01-29 |
2015-01-01 |
Boehringer Ingelheim Int |
小兒科病人糖尿病之治療
|
NZ594044A
(en)
|
2009-02-13 |
2014-08-29 |
Boehringer Ingelheim Int |
Antidiabetic medications comprising a dpp-4 inhibitor (linagliptin) optionally in combination with other antidiabetics
|
WO2010108503A1
(en)
|
2009-03-24 |
2010-09-30 |
Life & Brain Gmbh |
Promotion of neuronal integration in neural stem cell grafts
|
US8530492B2
(en)
|
2009-04-17 |
2013-09-10 |
Nektar Therapeutics |
Oligomer-protein tyrosine kinase inhibitor conjugates
|
MY155570A
(en)
|
2009-06-26 |
2015-10-30 |
Novartis Ag |
1, 3-disubstituted imidazolidin-2-one derivatives as inhibitors of cyp 17
|
US8293753B2
(en)
|
2009-07-02 |
2012-10-23 |
Novartis Ag |
Substituted 2-carboxamide cycloamino ureas
|
US8389526B2
(en)
|
2009-08-07 |
2013-03-05 |
Novartis Ag |
3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
|
EP2464649A1
(en)
|
2009-08-12 |
2012-06-20 |
Novartis AG |
Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation
|
JP5819831B2
(ja)
|
2009-08-17 |
2015-11-24 |
インテリカイン, エルエルシー |
複素環式化合物およびそれらの使用
|
JP5775871B2
(ja)
|
2009-08-20 |
2015-09-09 |
ノバルティス アーゲー |
ヘテロ環式オキシム化合物
|
EP2470502A1
(en)
|
2009-08-26 |
2012-07-04 |
Novartis AG |
Tetra-substituted heteroaryl compounds and their use as mdm2 and/or mdm4 modulators
|
IN2012DN02139A
(enEXAMPLES)
|
2009-09-10 |
2015-08-07 |
Novartis Ag |
|
AU2010302586C1
(en)
|
2009-10-02 |
2016-10-06 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions comprising BI-1356 and metformin
|
JP5466767B2
(ja)
|
2009-11-04 |
2014-04-09 |
ノバルティス アーゲー |
Mek阻害剤として有用なヘテロ環式スルホンアミド誘導体
|
WO2011064211A1
(en)
|
2009-11-25 |
2011-06-03 |
Novartis Ag |
Benzene-fused 6-membered oxygen-containing heterocyclic derivatives of bicyclic heteroaryls
|
CA2782179C
(en)
|
2009-11-27 |
2020-06-23 |
Boehringer Ingelheim International Gmbh |
Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
|
CA2781218A1
(en)
|
2009-12-08 |
2011-06-16 |
Novartis Ag |
Heterocyclic sulfonamide derivatives
|
US8440693B2
(en)
|
2009-12-22 |
2013-05-14 |
Novartis Ag |
Substituted isoquinolinones and quinazolinones
|
CU24130B1
(es)
|
2009-12-22 |
2015-09-29 |
Novartis Ag |
Isoquinolinonas y quinazolinonas sustituidas
|
JP2013522279A
(ja)
|
2010-03-18 |
2013-06-13 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
糖尿病及び関連状態の治療で用いるgpr119作動薬とddp−iv阻害薬リナグリプチンの組合せ
|
KR101927068B1
(ko)
|
2010-05-05 |
2018-12-10 |
베링거 인겔하임 인터내셔날 게엠베하 |
체중 감소 치료에 후속하는 dpp-4 억제제에 의한 순차적 병용 요법
|
CN102947274A
(zh)
|
2010-06-17 |
2013-02-27 |
诺瓦提斯公司 |
联苯基取代的1,3-二氢-苯并咪唑-2-亚基胺衍生物
|
EP2582681A1
(en)
|
2010-06-17 |
2013-04-24 |
Novartis AG |
Piperidinyl substituted 1,3-dihydro-benzoimidazol-2-ylideneamine derivatives
|
WO2011161217A2
(en)
|
2010-06-23 |
2011-12-29 |
Palacký University in Olomouc |
Targeting of vegfr2
|
KR102018038B1
(ko)
|
2010-06-24 |
2019-09-05 |
베링거 인겔하임 인터내셔날 게엠베하 |
당뇨병 요법
|
WO2011162343A1
(ja)
|
2010-06-25 |
2011-12-29 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
キナーゼ阻害作用を有する化合物の併用による抗腫瘍剤
|
MX2013000083A
(es)
|
2010-07-09 |
2013-02-26 |
Genentech Inc |
Anticuerpos de anti-neuropilina y metodos de uso.
|
AR082418A1
(es)
|
2010-08-02 |
2012-12-05 |
Novartis Ag |
Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico
|
JP2013537210A
(ja)
|
2010-09-16 |
2013-09-30 |
ノバルティス アーゲー |
17α−ヒドロキシラーゼ/C17,20−リアーゼ阻害剤
|
US9034883B2
(en)
|
2010-11-15 |
2015-05-19 |
Boehringer Ingelheim International Gmbh |
Vasoprotective and cardioprotective antidiabetic therapy
|
WO2012068483A1
(en)
|
2010-11-18 |
2012-05-24 |
Synta Pharmaceuticals Corp. |
Preselection of subjects for therapeutic treatment based on hypoxic status
|
JP2014503500A
(ja)
|
2010-11-18 |
2014-02-13 |
シンタ ファーマスーティカルズ コーポレーション |
低酸素状態に基づく酸素感受性薬剤による治療に適した被験体の事前選択
|
AU2012213080B2
(en)
|
2011-01-31 |
2014-03-27 |
Novartis Ag |
Novel heterocyclic derivatives
|
EP2673277A1
(en)
|
2011-02-10 |
2013-12-18 |
Novartis AG |
[1, 2, 4]triazolo [4, 3 -b]pyridazine compounds as inhibitors of the c-met tyrosine kinase
|
US9127000B2
(en)
|
2011-02-23 |
2015-09-08 |
Intellikine, LLC. |
Heterocyclic compounds and uses thereof
|
CN103492390A
(zh)
|
2011-03-08 |
2014-01-01 |
诺瓦提斯公司 |
氟苯基双环杂芳基化合物
|
KR101606250B1
(ko)
|
2011-03-23 |
2016-03-24 |
암젠 인크 |
Cdk 4/6 및 flt3의 융합된 트리사이클릭 이중 저해제
|
CA2828946C
(en)
|
2011-04-18 |
2016-06-21 |
Eisai R&D Management Co., Ltd. |
Therapeutic agent for tumor
|
AU2012249421B9
(en)
|
2011-04-28 |
2015-10-22 |
Novartis Ag |
17alpha-hydroxylase/C17,20-lyase inhibitors
|
EP3444363B1
(en)
|
2011-06-03 |
2020-11-25 |
Eisai R&D Management Co., Ltd. |
Biomarkers for prediciting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds
|
EP2718276A1
(en)
|
2011-06-09 |
2014-04-16 |
Novartis AG |
Heterocyclic sulfonamide derivatives
|
EA025384B1
(ru)
*
|
2011-06-16 |
2016-12-30 |
Корея Рисерч Инститьют Оф Кемикал Текнолоджи |
Производные 1,3-диоксоиндена, их фармацевтически приемлемая соль, способ их получения и фармацевтическая антивирусная композиция, содержащая их в качестве активного ингредиента
|
US8859535B2
(en)
|
2011-06-20 |
2014-10-14 |
Novartis Ag |
Hydroxy substituted isoquinolinone derivatives
|
US8859586B2
(en)
|
2011-06-20 |
2014-10-14 |
Novartis Ag |
Cyclohexyl isoquinolinone compounds
|
PL3517539T3
(pl)
|
2011-07-15 |
2023-04-24 |
Boehringer Ingelheim International Gmbh |
Podstawiona dimeryczna pochodna chinazoliny, sposób jej wytwarzania i jej zastosowanie w kompozycjach farmaceutycznych do leczenia cukrzycy typu I i II
|
US9745288B2
(en)
|
2011-08-16 |
2017-08-29 |
Indiana University Research And Technology Corporation |
Compounds and methods for treating cancer by inhibiting the urokinase receptor
|
WO2014081405A2
(en)
|
2011-08-17 |
2014-05-30 |
Dennis Brown |
Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dibromodulcitol
|
ES2691650T3
(es)
|
2011-09-15 |
2018-11-28 |
Novartis Ag |
3-(quinolin-6-il-tio)-[1,2,4]-triazolo-[4,3-a]-piridinas 6-sustituidas como inhibidores de tirosina quinasa c-Met
|
AU2012327954B2
(en)
|
2011-10-28 |
2015-11-26 |
Novartis Ag |
Novel purine derivatives and their use in the treatment of disease
|
JP5992054B2
(ja)
|
2011-11-29 |
2016-09-14 |
ノバルティス アーゲー |
ピラゾロピロリジン化合物
|
CN104125953A
(zh)
|
2011-12-23 |
2014-10-29 |
诺华股份有限公司 |
用于抑制bcl2与结合配偶体相互作用的化合物
|
MX2014007729A
(es)
|
2011-12-23 |
2015-01-12 |
Novartis Ag |
Compuestos para inhibir la interaccion de bcl2 con los componentes de enlace.
|
US20140357666A1
(en)
|
2011-12-23 |
2014-12-04 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
CN104125954A
(zh)
|
2011-12-23 |
2014-10-29 |
诺华股份有限公司 |
用于抑制bcl2与结合配偶体相互作用的化合物
|
KR20140107578A
(ko)
|
2011-12-23 |
2014-09-04 |
노파르티스 아게 |
Bcl2와 결합 파트너의 상호작용을 억제하기 위한 화합물
|
US20130172244A1
(en)
|
2011-12-29 |
2013-07-04 |
Thomas Klein |
Subcutaneous therapeutic use of dpp-4 inhibitor
|
UY34591A
(es)
|
2012-01-26 |
2013-09-02 |
Novartis Ag |
Compuestos de imidazopirrolidinona
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
JP2015512425A
(ja)
|
2012-04-03 |
2015-04-27 |
ノバルティス アーゲー |
チロシンキナーゼ阻害剤との組合せ製品及びそれらの使用
|
JP6224084B2
(ja)
|
2012-05-14 |
2017-11-01 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
糸球体上皮細胞関連障害及び/又はネフローゼ症候群の治療に用いるdpp−4阻害薬としてのキサンチン誘導体
|
US20130303554A1
(en)
|
2012-05-14 |
2013-11-14 |
Boehringer Ingelheim International Gmbh |
Use of a dpp-4 inhibitor in sirs and/or sepsis
|
CN104349779A
(zh)
|
2012-05-16 |
2015-02-11 |
诺华股份有限公司 |
Pi-3激酶抑制剂的剂量方案
|
CN104321325B
(zh)
|
2012-05-24 |
2016-11-16 |
诺华股份有限公司 |
吡咯并吡咯烷酮化合物
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
JP6374862B2
(ja)
|
2012-05-24 |
2018-08-15 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
自己免疫性糖尿病、特に、ladaの治療に使用するためのdpp−4阻害剤としてのキサンチン誘導体
|
KR20150034209A
(ko)
|
2012-06-26 |
2015-04-02 |
델 마 파마슈티컬스 인코포레이티드 |
디안하이드로갈락티톨, 디아세틸디안하이드로갈락티톨, 디브로모둘시톨, 또는 그의 유사체 또는 유도체를 이용하여 유전학적 다형성이 있는 환자에 있어서 티로신-키나아제-억제제 내성 악성종양, ahi1 조절곤란 또는 돌연변이를 치료하는 방법
|
US9505749B2
(en)
|
2012-08-29 |
2016-11-29 |
Amgen Inc. |
Quinazolinone compounds and derivatives thereof
|
JP6293168B2
(ja)
|
2012-12-14 |
2018-03-14 |
コーリア リサーチ インスティテュート オブ ケミカル テクノロジー |
新規の化合物、その薬学的に許容可能な塩又は光学異性体、それを作製する方法、及びそれを有効成分として含有するウイルス疾患の予防又は治療用の医薬組成物
|
US9334239B2
(en)
|
2012-12-21 |
2016-05-10 |
Eisai R&D Management Co., Ltd. |
Amorphous form of quinoline derivative, and method for producing same
|
US9556180B2
(en)
|
2013-01-22 |
2017-01-31 |
Novartis Ag |
Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the P53/MDM2 interaction
|
US9403827B2
(en)
|
2013-01-22 |
2016-08-02 |
Novartis Ag |
Substituted purinone compounds
|
WO2014124860A1
(en)
|
2013-02-14 |
2014-08-21 |
Boehringer Ingelheim International Gmbh |
Specific pde4b-inhibitors for the treatment of diabetes mellitus
|
EP2968340A4
(en)
|
2013-03-15 |
2016-08-10 |
Intellikine Llc |
COMBINING KINASE INHIBITORS AND USES THEREOF
|
EA037712B1
(ru)
|
2013-03-15 |
2021-05-13 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Кардио- и нефропротективная противодиабетическая терапия
|
WO2014155268A2
(en)
|
2013-03-25 |
2014-10-02 |
Novartis Ag |
Fgf-r tyrosine kinase activity inhibitors - use in diseases associated with lack of or reduced snf5 activity
|
AU2014251038A1
(en)
|
2013-04-08 |
2015-11-26 |
Dennis M. Brown |
Therapeutic benefit of suboptimally administered chemical compounds
|
CN105264380B
(zh)
|
2013-05-14 |
2017-09-05 |
卫材R&D管理有限公司 |
用于预测和评价子宫内膜癌受试者对乐伐替尼化合物响应性的生物标志
|
WO2015022664A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
US9227969B2
(en)
|
2013-08-14 |
2016-01-05 |
Novartis Ag |
Compounds and compositions as inhibitors of MEK
|
WO2015022663A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
WO2015084804A1
(en)
|
2013-12-03 |
2015-06-11 |
Novartis Ag |
Combination of mdm2 inhibitor and braf inhibitor and their use
|
KR20160095035A
(ko)
|
2013-12-06 |
2016-08-10 |
노파르티스 아게 |
알파-이소형 선택성 포스파티딜이노시톨 3-키나제 억제제를 위한 투여 요법
|
BR112017001695A2
(pt)
|
2014-07-31 |
2017-11-21 |
Novartis Ag |
terapia de combinação
|
JO3783B1
(ar)
|
2014-08-28 |
2021-01-31 |
Eisai R&D Man Co Ltd |
مشتق كوينولين عالي النقاء وطريقة لإنتاجه
|
US20170340733A1
(en)
|
2014-12-19 |
2017-11-30 |
Novartis Ag |
Combination therapies
|
HK1247955A1
(zh)
|
2015-01-08 |
2018-10-05 |
小利兰.斯坦福大学托管委员会 |
提供骨、骨髓及软骨的诱导的因子和细胞
|
US20180093956A1
(en)
*
|
2015-02-06 |
2018-04-05 |
Abbvie Inc. |
Substituted phthalazines
|
DK3263106T3
(da)
|
2015-02-25 |
2024-01-08 |
Eisai R&D Man Co Ltd |
Fremgangsmåde til undertrykkelse af bitterhed af quinolinderivat
|
KR20250020678A
(ko)
|
2015-03-04 |
2025-02-11 |
머크 샤프 앤드 돔 엘엘씨 |
암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
|
MX2017011597A
(es)
|
2015-03-10 |
2018-05-11 |
Aduro Biotech Inc |
Composiciones y metodos para activar la señalizacion dependiente del "estimulador del gen de interferon".
|
US11369623B2
(en)
|
2015-06-16 |
2022-06-28 |
Prism Pharma Co., Ltd. |
Anticancer combination of a CBP/catenin inhibitor and an immune checkpoint inhibitor
|
ES2887426T3
(es)
|
2015-08-20 |
2021-12-22 |
Eisai R&D Man Co Ltd |
Lenvatinib combinado con etopósido e ifosfamida para su uso en el tratamiento de un tumor
|
US20180280370A1
(en)
|
2015-11-02 |
2018-10-04 |
Novartis Ag |
Dosage regimen for a phosphatidylinositol 3-kinase inhibitor
|
NZ747331A
(en)
|
2016-06-10 |
2025-06-27 |
Boehringer Ingelheim Int |
Combinations of linagliptin and metformin
|
WO2018009466A1
(en)
|
2016-07-05 |
2018-01-11 |
Aduro Biotech, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
WO2018060833A1
(en)
|
2016-09-27 |
2018-04-05 |
Novartis Ag |
Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib
|
CN110366550A
(zh)
|
2016-12-22 |
2019-10-22 |
美国安进公司 |
作为用于治疗肺癌、胰腺癌或结直肠癌的KRAS G12C抑制剂的苯并异噻唑、异噻唑并[3,4-b]吡啶、喹唑啉、酞嗪、吡啶并[2,3-d]哒嗪和吡啶并[2,3-d]嘧啶衍生物
|
US12303505B2
(en)
|
2017-02-08 |
2025-05-20 |
Eisai R&D Management Co., Ltd. |
Tumor-treating pharmaceutical composition
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
CA3061888A1
(en)
|
2017-05-16 |
2018-11-22 |
Eisai R&D Management Co., Ltd. |
Treatment of hepatocellular carcinoma
|
JOP20190272A1
(ar)
|
2017-05-22 |
2019-11-21 |
Amgen Inc |
مثبطات kras g12c وطرق لاستخدامها
|
EP3679040B1
(en)
|
2017-09-08 |
2022-08-03 |
Amgen Inc. |
Inhibitors of kras g12c and methods of using the same
|
CA3079076A1
(en)
|
2017-10-18 |
2019-04-25 |
Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus |
Methods and compounds for improved immune cell therapy
|
EP3730483B1
(en)
|
2017-12-21 |
2023-08-30 |
Hefei Institutes of Physical Science, Chinese Academy of Sciences |
Class of pyrimidine derivative kinase inhibitors
|
MA52496A
(fr)
|
2018-05-04 |
2021-03-10 |
Amgen Inc |
Inhibiteurs de kras g12c et leurs procédés d'utilisation
|
AU2019262589B2
(en)
|
2018-05-04 |
2022-07-07 |
Amgen Inc. |
KRAS G12C inhibitors and methods of using the same
|
CA3099045A1
(en)
|
2018-05-10 |
2019-11-14 |
Amgen Inc. |
Kras g12c inhibitors for the treatment of cancer
|
CA3098885A1
(en)
|
2018-06-01 |
2019-12-05 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
AU2019284472B2
(en)
|
2018-06-11 |
2024-05-30 |
Amgen Inc. |
KRAS G12C inhibitors for treating cancer
|
US11285156B2
(en)
|
2018-06-12 |
2022-03-29 |
Amgen Inc. |
Substituted piperazines as KRAS G12C inhibitors
|
JP2021530510A
(ja)
|
2018-07-17 |
2021-11-11 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
心臓に安全な抗糖尿病療法
|
AU2019306036B2
(en)
|
2018-07-17 |
2025-05-15 |
Boehringer Ingelheim International Gmbh |
Cardio- and renosafe antidiabetic therapy
|
JP7516029B2
(ja)
|
2018-11-16 |
2024-07-16 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤化合物の重要な中間体の改良合成法
|
JP7377679B2
(ja)
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法
|
JP7454572B2
(ja)
|
2018-11-19 |
2024-03-22 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤及びその使用方法
|
WO2020132651A1
(en)
|
2018-12-20 |
2020-06-25 |
Amgen Inc. |
Kif18a inhibitors
|
AR117490A1
(es)
|
2018-12-20 |
2021-08-11 |
Amgen Inc |
Inhibidores de kif18a
|
MA54546A
(fr)
|
2018-12-20 |
2022-03-30 |
Amgen Inc |
Amides d'hétéroaryle utiles en tant qu'inhibiteurs de kif18a
|
AU2019401495B2
(en)
|
2018-12-20 |
2025-06-26 |
Amgen Inc. |
Heteroaryl amides useful as KIF18A inhibitors
|
CN113767100A
(zh)
|
2019-03-01 |
2021-12-07 |
锐新医药公司 |
双环杂芳基化合物及其用途
|
KR20210146288A
(ko)
|
2019-03-01 |
2021-12-03 |
레볼루션 메디슨즈, 인크. |
이환식 헤테로사이클릴 화합물 및 이의 용도
|
CA3140044A1
(en)
|
2019-05-14 |
2020-11-19 |
The Scripps Research Institute |
Compounds for the treatment of neurodegenerative and metabolic disorders
|
EP3738593A1
(en)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosing of kras inhibitor for treatment of cancers
|
BR112021023277A2
(pt)
|
2019-05-21 |
2022-01-04 |
Amgen Inc |
Formas em estado sólido
|
AU2020326627A1
(en)
|
2019-08-02 |
2022-03-17 |
Amgen Inc. |
KIF18A inhibitors
|
MX2022001302A
(es)
|
2019-08-02 |
2022-03-02 |
Amgen Inc |
Inhibidores de kif18a.
|
US20220281843A1
(en)
|
2019-08-02 |
2022-09-08 |
Amgen Inc. |
Kif18a inhibitors
|
WO2021026099A1
(en)
|
2019-08-02 |
2021-02-11 |
Amgen Inc. |
Kif18a inhibitors
|
WO2021081212A1
(en)
|
2019-10-24 |
2021-04-29 |
Amgen Inc. |
Pyridopyrimidine derivatives useful as kras g12c and kras g12d inhibitors in the treatment of cancer
|
JP2022553857A
(ja)
|
2019-11-04 |
2022-12-26 |
レボリューション メディシンズ インコーポレイテッド |
Ras阻害剤
|
JP2022553858A
(ja)
|
2019-11-04 |
2022-12-26 |
レボリューション メディシンズ インコーポレイテッド |
Ras阻害剤
|
WO2021091956A1
(en)
|
2019-11-04 |
2021-05-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
AU2020380315A1
(en)
|
2019-11-08 |
2022-05-26 |
Revolution Medicines, Inc. |
Bicyclic heteroaryl compounds and uses thereof
|
CN120463705A
(zh)
|
2019-11-14 |
2025-08-12 |
美国安进公司 |
Kras g12c抑制剂化合物的改善的合成
|
AU2020383535A1
(en)
|
2019-11-14 |
2022-05-05 |
Amgen Inc. |
Improved synthesis of KRAS G12C inhibitor compound
|
WO2021097256A1
(en)
|
2019-11-14 |
2021-05-20 |
Cohbar, Inc. |
Cxcr4 antagonist peptides
|
JP2023505100A
(ja)
|
2019-11-27 |
2023-02-08 |
レボリューション メディシンズ インコーポレイテッド |
共有ras阻害剤及びその使用
|
IL294484A
(en)
|
2020-01-07 |
2022-09-01 |
Revolution Medicines Inc |
Shp2 inhibitor dosing and methods of treating cancer
|
CN120590351A
(zh)
|
2020-04-20 |
2025-09-05 |
诺华股份有限公司 |
抗病毒素1,3-二氧代茚化合物
|
US12286423B2
(en)
|
2020-04-20 |
2025-04-29 |
Novartis Ag |
Antiviral 1,3-di-oxo-indene compounds
|
IL299131A
(en)
|
2020-06-18 |
2023-02-01 |
Revolution Medicines Inc |
Methods for delaying, preventing and treating acquired resistance to RAS inhibitors
|
EP4208261A1
(en)
|
2020-09-03 |
2023-07-12 |
Revolution Medicines, Inc. |
Use of sos1 inhibitors to treat malignancies with shp2 mutations
|
CA3194067A1
(en)
|
2020-09-15 |
2022-03-24 |
Revolution Medicines, Inc. |
Ras inhibitors
|
EP4267250A1
(en)
|
2020-12-22 |
2023-11-01 |
Qilu Regor Therapeutics Inc. |
Sos1 inhibitors and uses thereof
|
CN117355303A
(zh)
*
|
2021-01-28 |
2024-01-05 |
佛罗里达大学研究基金会公司 |
化合物及其用于治疗神经退行性、退行性和代谢病症的用途
|
PE20240089A1
(es)
|
2021-05-05 |
2024-01-16 |
Revolution Medicines Inc |
Inhibidores de ras para el tratamiento del cancer
|
IL308193A
(en)
|
2021-05-05 |
2024-01-01 |
Revolution Medicines Inc |
RAS inhibitors
|
CN117500811A
(zh)
|
2021-05-05 |
2024-02-02 |
锐新医药公司 |
共价ras抑制剂及其用途
|
US20250059182A1
(en)
*
|
2021-06-21 |
2025-02-20 |
Mirati Therapeutics, Inc. |
Sos1 inhibitors
|
AR127308A1
(es)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
Inhibidores ras
|
CN119212994A
(zh)
|
2021-12-17 |
2024-12-27 |
建新公司 |
作为shp2抑制剂的吡唑并吡嗪化合物
|
WO2023121413A1
(ko)
*
|
2021-12-24 |
2023-06-29 |
제일약품주식회사 |
신규한 바이사이클릭 헤테로사이클릴 화합물 및 이의 용도
|
EP4227307A1
(en)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
EP4489755A1
(en)
|
2022-03-08 |
2025-01-15 |
Revolution Medicines, Inc. |
Methods for treating immune refractory lung cancer
|
CN119998298A
(zh)
|
2022-06-10 |
2025-05-13 |
锐新医药公司 |
大环ras抑制剂
|
WO2024081916A1
(en)
|
2022-10-14 |
2024-04-18 |
Black Diamond Therapeutics, Inc. |
Methods of treating cancers using isoquinoline or 6-aza-quinoline derivatives
|
TW202504611A
(zh)
|
2023-03-30 |
2025-02-01 |
美商銳新醫藥公司 |
用於誘導ras gtp水解之組合物及其用途
|
WO2024211712A1
(en)
|
2023-04-07 |
2024-10-10 |
Revolution Medicines, Inc. |
Condensed macrocyclic compounds as ras inhibitors
|
WO2024211663A1
(en)
|
2023-04-07 |
2024-10-10 |
Revolution Medicines, Inc. |
Condensed macrocyclic compounds as ras inhibitors
|
WO2024216016A1
(en)
|
2023-04-14 |
2024-10-17 |
Revolution Medicines, Inc. |
Crystalline forms of a ras inhibitor
|
US20240352038A1
(en)
|
2023-04-14 |
2024-10-24 |
Revolution Medicines, Inc. |
Crystalline forms of ras inhibitors, compositions containing the same, and methods of use thereof
|
WO2024229406A1
(en)
|
2023-05-04 |
2024-11-07 |
Revolution Medicines, Inc. |
Combination therapy for a ras related disease or disorder
|
US20250049810A1
(en)
|
2023-08-07 |
2025-02-13 |
Revolution Medicines, Inc. |
Methods of treating a ras protein-related disease or disorder
|
US20250154171A1
(en)
|
2023-10-12 |
2025-05-15 |
Revolution Medicines, Inc. |
Ras inhibitors
|
WO2025137507A1
(en)
|
2023-12-22 |
2025-06-26 |
Regor Pharmaceuticals, Inc. |
Sos1 inhibitors and uses thereof
|
WO2025171296A1
(en)
|
2024-02-09 |
2025-08-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|