CY1122252T1 - Ενεσιμο παρασκευασμα - Google Patents

Ενεσιμο παρασκευασμα

Info

Publication number
CY1122252T1
CY1122252T1 CY20191100912T CY191100912T CY1122252T1 CY 1122252 T1 CY1122252 T1 CY 1122252T1 CY 20191100912 T CY20191100912 T CY 20191100912T CY 191100912 T CY191100912 T CY 191100912T CY 1122252 T1 CY1122252 T1 CY 1122252T1
Authority
CY
Cyprus
Prior art keywords
injectable preparation
present
pascal
viscosity
point
Prior art date
Application number
CY20191100912T
Other languages
English (en)
Inventor
Daiki KANEKO
Takakuni Matsuda
Yusuke HOSHIKA
Original Assignee
Otsuka Pharmaceutical Co., Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48614096&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1122252(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharmaceutical Co., Ltd filed Critical Otsuka Pharmaceutical Co., Ltd
Publication of CY1122252T1 publication Critical patent/CY1122252T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Psychiatry (AREA)
  • Dispersion Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Στόχος της παρούσας εφεύρεσης αποτελεί η παροχή ενός σταθερού κατά την αποθήκευση ενέσιμου παρασκευάσματος το οποίο περιλαμβάνει μία σύνθεση η οποία περιέχει ένα ελαχίστως διαλυτό φάρμακο ως δραστικό συστατικό και ένα μέσο διασποράς. Έτερος στόχος της παρούσας εφεύρεσης είναι η παροχή μίας συμπαγούς, ελαφριάς προπληρωθείσας σύριγγας πληρώνοντας τη σύριγγα με το ενέσιμο παρασκεύασμα. Η παρούσα εφεύρεση παρέχει ένα ενέσιμο παρασκεύασμα το οποίο περιλαμβάνει μία σύνθεση η οποία περιέχει ένα ελαχίστως διαλυτό φάρμακο, ένα μέσο διασποράς και έναν ειδικό παράγοντα εναιώρησης, όπου η σύνθεση διαθέτει ιξώδες της τάξεως των 40 pascal-δευτερόλεπτο ή περισσότερο σε ένα τουλάχιστον σημείο στην κλίμακα του λόγου ταχύτητας απόχυσης και κλίσης από 0,01 έως 0,02 s-1 και διαθέτει ιξώδες της τάξεως των 0,2 pascal-δευτερόλεπτο ή λιγότερο σε ένα τουλάχιστον σημείο στην κλίμακα του λόγου ταχύτητας απόχυσης και κλίσης από 900 έως 1.000 s-1, όπως μετράται.
CY20191100912T 2012-04-23 2019-08-28 Ενεσιμο παρασκευασμα CY1122252T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261636938P 2012-04-23 2012-04-23
US201361792089P 2013-03-15 2013-03-15
PCT/JP2013/062683 WO2013162048A1 (en) 2012-04-23 2013-04-23 Injectable preparation

Publications (1)

Publication Number Publication Date
CY1122252T1 true CY1122252T1 (el) 2020-11-25

Family

ID=48614096

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20191100912T CY1122252T1 (el) 2012-04-23 2019-08-28 Ενεσιμο παρασκευασμα

Country Status (32)

Country Link
US (8) US20150093442A1 (el)
EP (2) EP2841054B2 (el)
JP (6) JP6234996B2 (el)
KR (4) KR20210116702A (el)
CN (3) CN114344259B (el)
AR (1) AR090776A1 (el)
AU (5) AU2013253374B2 (el)
BR (1) BR112014026307B1 (el)
CA (2) CA2869889C (el)
CO (1) CO7151500A2 (el)
CY (1) CY1122252T1 (el)
DK (1) DK2841054T4 (el)
EA (1) EA026619B1 (el)
ES (1) ES2743706T5 (el)
HK (2) HK1206988A1 (el)
HR (1) HRP20191366T4 (el)
HU (1) HUE045979T2 (el)
IL (1) IL235299B (el)
JO (2) JOP20200109A1 (el)
LT (1) LT2841054T (el)
MX (1) MX359241B (el)
MY (2) MY198007A (el)
NZ (1) NZ630335A (el)
PH (2) PH12014502379B1 (el)
PL (1) PL2841054T5 (el)
PT (1) PT2841054T (el)
SG (3) SG10201608753UA (el)
SI (1) SI2841054T2 (el)
TW (4) TW202126303A (el)
UA (1) UA115444C2 (el)
WO (1) WO2013162048A1 (el)
ZA (1) ZA201407335B (el)

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Also Published As

Publication number Publication date
PT2841054T (pt) 2019-09-09
TW202126303A (zh) 2021-07-16
DK2841054T3 (da) 2019-09-09
SI2841054T1 (sl) 2019-09-30
US12016927B2 (en) 2024-06-25
US20200179517A1 (en) 2020-06-11
US20210085794A1 (en) 2021-03-25
PH12014502379A1 (en) 2015-01-12
BR112014026307B1 (pt) 2022-10-11
CA2869889A1 (en) 2013-10-31
ES2743706T3 (es) 2020-02-20
AU2017228608B2 (en) 2018-10-18
MY198007A (en) 2023-07-25
CN104470499B (zh) 2018-03-16
JP2021008512A (ja) 2021-01-28
JP6234996B2 (ja) 2017-11-22
AU2017228608C1 (en) 2019-02-21
WO2013162048A1 (en) 2013-10-31
US20230390399A1 (en) 2023-12-07
EA201491685A1 (ru) 2015-04-30
JP6470378B2 (ja) 2019-02-13
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