CO7151500A2 - Preparación inyectable - Google Patents
Preparación inyectableInfo
- Publication number
- CO7151500A2 CO7151500A2 CO14256422A CO14256422A CO7151500A2 CO 7151500 A2 CO7151500 A2 CO 7151500A2 CO 14256422 A CO14256422 A CO 14256422A CO 14256422 A CO14256422 A CO 14256422A CO 7151500 A2 CO7151500 A2 CO 7151500A2
- Authority
- CO
- Colombia
- Prior art keywords
- injectable preparation
- present
- viscosity
- composition
- dispersion medium
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 4
- 239000002612 dispersion medium Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229940071643 prefilled syringe Drugs 0.000 abstract 1
- 239000000375 suspending agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Dispersion Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un objeto de la presente invención es brindar unapreparación inyectable estable durante el almacenamientoque comprende una composición que comprende un fármacopoco soluble como ingrediente activo, y que ademáscomprende un medio de dispersión. Otro objeto de lapresente invención es brindar una jeringa prellenadacompacta, liviana mediante el prellenado de la jeringacon la preparación inyectable. La presente invenciónbrinda una preparación inyectable que comprende unacomposición que comprende un fármaco poco soluble, unmedio de dispersión y un agente de suspensión específicoque tiene una viscosidad de 40 Pa·s o más en, al menos,un punto en el rango de velocidad de corte que oscilaentre 0,01 y 0,02 s-1 y tiene una viscosidad de 0,2 Pa·s oinferior, en al menos un punto en el rango de velocidadde corte que oscila entre 900 y 1,000 s-1, como se hamedido.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261636938P | 2012-04-23 | 2012-04-23 | |
US201361792089P | 2013-03-15 | 2013-03-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO7151500A2 true CO7151500A2 (es) | 2014-12-29 |
Family
ID=48614096
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO14256422A CO7151500A2 (es) | 2012-04-23 | 2014-11-21 | Preparación inyectable |
Country Status (32)
Country | Link |
---|---|
US (8) | US20150093442A1 (es) |
EP (2) | EP2841054B2 (es) |
JP (6) | JP6234996B2 (es) |
KR (4) | KR20210116702A (es) |
CN (3) | CN114344259B (es) |
AR (1) | AR090776A1 (es) |
AU (5) | AU2013253374B2 (es) |
BR (1) | BR112014026307B1 (es) |
CA (2) | CA2869889C (es) |
CO (1) | CO7151500A2 (es) |
CY (1) | CY1122252T1 (es) |
DK (1) | DK2841054T4 (es) |
EA (1) | EA026619B1 (es) |
ES (1) | ES2743706T5 (es) |
HK (2) | HK1206988A1 (es) |
HR (1) | HRP20191366T4 (es) |
HU (1) | HUE045979T2 (es) |
IL (1) | IL235299B (es) |
JO (2) | JOP20200109A1 (es) |
LT (1) | LT2841054T (es) |
MX (1) | MX359241B (es) |
MY (2) | MY198007A (es) |
NZ (1) | NZ630335A (es) |
PH (2) | PH12014502379B1 (es) |
PL (1) | PL2841054T5 (es) |
PT (1) | PT2841054T (es) |
SG (3) | SG10201608753UA (es) |
SI (1) | SI2841054T2 (es) |
TW (4) | TW202126303A (es) |
UA (1) | UA115444C2 (es) |
WO (1) | WO2013162048A1 (es) |
ZA (1) | ZA201407335B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JOP20200109A1 (ar) | 2012-04-23 | 2017-06-16 | Otsuka Pharma Co Ltd | مستحضر قابل للحقن |
AR090775A1 (es) | 2012-04-23 | 2014-12-03 | Otsuka Pharma Co Ltd | Preparado inyectable |
TWI562991B (en) * | 2012-04-23 | 2016-12-21 | Otsuka Pharma Co Ltd | Dihydrate of benzothiophene compound or of a salt thereof, and process for producing the same |
CN105461703B (zh) * | 2014-12-29 | 2019-05-17 | 深圳市泛谷药业股份有限公司 | 一种brexpiprazole的制备方法 |
JP6513461B2 (ja) * | 2015-04-14 | 2019-05-15 | 帝國製薬株式会社 | ブレクスピプラゾールの経皮吸収製剤 |
CN104829603A (zh) * | 2015-05-19 | 2015-08-12 | 杭州新博思生物医药有限公司 | A晶型依匹唑派盐酸盐及其制备方法 |
US10501450B2 (en) | 2016-02-01 | 2019-12-10 | Hexal Ag | Anhydrate-free polymorphically pure micronized crystalline brexpiprazole di-hydrate for use in intramuscular injectable sustained release formulations |
CN110198742B (zh) * | 2017-01-26 | 2021-11-30 | 四川瀛瑞医药科技有限公司 | 一种纳米炭-铁复合体系及其组合物、制备方法和用途 |
WO2019213286A1 (en) * | 2018-05-02 | 2019-11-07 | LifeMax Laboratories, Inc. | Extended release suspension formulation of lurasidone |
US20210401775A1 (en) * | 2018-11-02 | 2021-12-30 | Amaterasu Lifesciences Llp | A liquid injectable composition |
WO2021199076A1 (en) * | 2020-03-30 | 2021-10-07 | Cipla Limited | Injectable aripiprazole formulation |
TW202200141A (zh) * | 2020-04-01 | 2022-01-01 | 日商大塚製藥股份有限公司 | 阿立哌唑治療之劑量起始方法 |
US20230372317A1 (en) * | 2020-10-27 | 2023-11-23 | Pts Consulting, Llc | A liquid injectable composition of donepezil |
US11229644B1 (en) * | 2020-12-31 | 2022-01-25 | Lake O'hara Llc | Methods of treating psychiatric disorders in obese patients with brexpiprazole |
US11910794B2 (en) * | 2021-03-08 | 2024-02-27 | Monsanto Technology Llc | Solutions and methods for long-term pollen storage |
WO2023067664A1 (ja) * | 2021-10-18 | 2023-04-27 | 大塚製薬株式会社 | ベンゾチオフェン化合物の新規結晶形及びその製造方法 |
CN117529309A (zh) * | 2022-06-16 | 2024-02-06 | 江苏慧聚药业股份有限公司 | 药物组合物及依匹哌唑口溶膜 |
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AR090245A1 (es) | 2012-03-06 | 2014-10-29 | Otsuka Pharma Co Ltd | Preparacion solida oral de liberacion sostenida, metodo de preparacion |
JOP20200109A1 (ar) | 2012-04-23 | 2017-06-16 | Otsuka Pharma Co Ltd | مستحضر قابل للحقن |
TWI562991B (en) | 2012-04-23 | 2016-12-21 | Otsuka Pharma Co Ltd | Dihydrate of benzothiophene compound or of a salt thereof, and process for producing the same |
AR090775A1 (es) | 2012-04-23 | 2014-12-03 | Otsuka Pharma Co Ltd | Preparado inyectable |
-
2012
- 2012-04-23 JO JOP/2020/0109A patent/JOP20200109A1/ar unknown
-
2013
- 2013-04-22 AR ARP130101321A patent/AR090776A1/es not_active Application Discontinuation
- 2013-04-23 TW TW109130917A patent/TW202126303A/zh unknown
- 2013-04-23 ES ES13728542T patent/ES2743706T5/es active Active
- 2013-04-23 CA CA2869889A patent/CA2869889C/en active Active
- 2013-04-23 KR KR1020217029406A patent/KR20210116702A/ko not_active Application Discontinuation
- 2013-04-23 UA UAA201411954A patent/UA115444C2/uk unknown
- 2013-04-23 KR KR1020247015029A patent/KR20240068788A/ko not_active Application Discontinuation
- 2013-04-23 CA CA3120297A patent/CA3120297A1/en active Pending
- 2013-04-23 PT PT13728542T patent/PT2841054T/pt unknown
- 2013-04-23 MX MX2014012811A patent/MX359241B/es active IP Right Grant
- 2013-04-23 SG SG10201608753UA patent/SG10201608753UA/en unknown
- 2013-04-23 NZ NZ630335A patent/NZ630335A/en unknown
- 2013-04-23 MY MYPI2018001894A patent/MY198007A/en unknown
- 2013-04-23 PL PL13728542.5T patent/PL2841054T5/pl unknown
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