GB864100A - Therapeutic pencillin compositions and the preparation thereof - Google Patents

Therapeutic pencillin compositions and the preparation thereof

Info

Publication number
GB864100A
GB864100A GB9095/58A GB909558A GB864100A GB 864100 A GB864100 A GB 864100A GB 9095/58 A GB9095/58 A GB 9095/58A GB 909558 A GB909558 A GB 909558A GB 864100 A GB864100 A GB 864100A
Authority
GB
United Kingdom
Prior art keywords
chloride
derivative
penicillin
urea
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB9095/58A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Charles Pfizer and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc, Charles Pfizer and Co Inc filed Critical Pfizer Inc
Publication of GB864100A publication Critical patent/GB864100A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Injectable suspensions comprise an aqueous suspension of a water-insoluble salt of penicillin and 0.5 to 10% of choline or a water-soluble derivative thereof. About 3 to 10% of urea or a derivative, 1 to 5% of a parenterally acceptable suspending agent and about 0.25 to 5% (based on the weight of the penicillin salt) of a parenterally acceptable buffer. Preservatives may also be added. The penicillin salt may be that with procaine, dibenzylethylenediamine, N - benzyl - N1 - (3 - ethoxy - 4 - hydroxy)-benzyl ethylenediamine, 2-chloroprocaine and N,N1 - di - (4 - methoxybenzyl) ethylene diamine. The choline derivative may be the chloride, dihydrogen tartrate, dihydrogen citrate or chloride carbamate. Examples of urea derivatives are thiocarbamide, carbamyl chloride, urea nitrate, thiomethane, lower (up to four carbon atoms) alkyl carbamates.
GB9095/58A 1957-04-09 1958-03-21 Therapeutic pencillin compositions and the preparation thereof Expired GB864100A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US864100XA 1957-04-09 1957-04-09

Publications (1)

Publication Number Publication Date
GB864100A true GB864100A (en) 1961-03-29

Family

ID=22198386

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9095/58A Expired GB864100A (en) 1957-04-09 1958-03-21 Therapeutic pencillin compositions and the preparation thereof

Country Status (1)

Country Link
GB (1) GB864100A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2273655A (en) * 1992-12-08 1994-06-29 Bimeda Res Dev Ltd Veterinary compositions for treating mastitis
WO2013162048A1 (en) * 2012-04-23 2013-10-31 Otsuka Pharmaceutical Co., Ltd. Injectable preparation

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2273655A (en) * 1992-12-08 1994-06-29 Bimeda Res Dev Ltd Veterinary compositions for treating mastitis
GB2273655B (en) * 1992-12-08 1997-01-08 Bimeda Res Dev Ltd Veterinary compositions for the treatment of mastitis
WO2013162048A1 (en) * 2012-04-23 2013-10-31 Otsuka Pharmaceutical Co., Ltd. Injectable preparation
KR20150003861A (en) * 2012-04-23 2015-01-09 오쓰까 세이야꾸 가부시키가이샤 Injectable prepararion
EA026619B1 (en) * 2012-04-23 2017-04-28 Оцука Фармасьютикал Ко., Лтд. Injectable preparation
AU2013253374B2 (en) * 2012-04-23 2017-06-15 Otsuka Pharmaceutical Co., Ltd. Injectable preparation
CN104470499B (en) * 2012-04-23 2018-03-16 大塚制药株式会社 Injectable formulation
AU2017228608B2 (en) * 2012-04-23 2018-10-18 Otsuka Pharmaceutical Co., Ltd. Injectable preparation
AU2017228608C1 (en) * 2012-04-23 2019-02-21 Otsuka Pharmaceutical Co., Ltd. Injectable preparation
US10517951B2 (en) 2012-04-23 2019-12-31 Otsuka Pharmaceutical Co., Ltd. Injectable preparation
US11097007B2 (en) 2012-04-23 2021-08-24 Otsuka Pharmaceutical Co., Ltd. Injectable preparation
AU2020204200B2 (en) * 2012-04-23 2022-06-30 Otsuka Pharmaceutical Co., Ltd. Injectable preparation
US11638757B2 (en) 2012-04-23 2023-05-02 Otsuka Pharmaceutical Co., Ltd. Injectable preparation
US12016927B2 (en) 2012-04-23 2024-06-25 Otsuka Pharmaceutical Co., Ltd. Injectable preparation

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