JO3410B1 - تركيبة أريبيبرازول مجفف بالتبريد - Google Patents
تركيبة أريبيبرازول مجفف بالتبريدInfo
- Publication number
- JO3410B1 JO3410B1 JOP/2012/0141A JOP20120141A JO3410B1 JO 3410 B1 JO3410 B1 JO 3410B1 JO P20120141 A JOP20120141 A JO P20120141A JO 3410 B1 JO3410 B1 JO 3410B1
- Authority
- JO
- Jordan
- Prior art keywords
- freeze
- aripiprazole
- dried
- dried aripiprazole
- aripiprazole formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Abstract
يتعلق الاختارع الحالي في أحد أهدافه بتوفير صيغة مسحوق أريبيبرازول مجففة بالتجميد تظهر قابلية جيدة للتشتت ويتم تشتيتها بسهولة في معلق متجانس عند إعادة تكوينها باستخدام الماء. يوفر الاختراع الحالي صيغة أريبيبرازول مجففة بالتجميد تم الحصول عليها بواسطة عملية تشتمل على الخطوات الخاصة بالرش لتجميد معلق من أريبيبرازول مشتمل على (1) أريبيبرازول، (2) مادة ناقلة للأريبيبرازول، و (3) ماء للحقن، ومن ثم التجفيف.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161494088P | 2011-06-07 | 2011-06-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
JO3410B1 true JO3410B1 (ar) | 2019-10-20 |
Family
ID=46420491
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JOP/2012/0141A JO3410B1 (ar) | 2011-06-07 | 2012-06-03 | تركيبة أريبيبرازول مجفف بالتبريد |
Country Status (30)
Country | Link |
---|---|
US (3) | US11154507B2 (ar) |
EP (1) | EP2717859B1 (ar) |
JP (1) | JP6012637B2 (ar) |
KR (1) | KR102014124B1 (ar) |
CN (3) | CN106389357A (ar) |
AR (2) | AR086682A1 (ar) |
AU (1) | AU2012267810B2 (ar) |
BR (1) | BR112013031459B1 (ar) |
CA (1) | CA2837693C (ar) |
CO (1) | CO6842019A2 (ar) |
CY (1) | CY1118561T1 (ar) |
DK (1) | DK2717859T3 (ar) |
EA (1) | EA023951B1 (ar) |
ES (1) | ES2599479T3 (ar) |
HK (1) | HK1191245A1 (ar) |
HR (1) | HRP20161357T1 (ar) |
HU (1) | HUE031723T2 (ar) |
IL (1) | IL229467A (ar) |
JO (1) | JO3410B1 (ar) |
LT (1) | LT2717859T (ar) |
MX (1) | MX354473B (ar) |
MY (1) | MY166052A (ar) |
PL (1) | PL2717859T3 (ar) |
PT (1) | PT2717859T (ar) |
SG (1) | SG195046A1 (ar) |
SI (1) | SI2717859T1 (ar) |
TW (1) | TWI519320B (ar) |
UA (1) | UA112186C2 (ar) |
WO (1) | WO2012169662A1 (ar) |
ZA (1) | ZA201308868B (ar) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JOP20200109A1 (ar) | 2012-04-23 | 2017-06-16 | Otsuka Pharma Co Ltd | مستحضر قابل للحقن |
CN105663057A (zh) * | 2015-12-30 | 2016-06-15 | 中国药科大学 | 阿立哌唑长效混悬剂及其制备方法 |
US20190160002A1 (en) | 2016-07-28 | 2019-05-30 | Mylan Laboratories Limited | Process for preparing sterile aripiprazole formulation |
CN115768407A (zh) * | 2020-05-21 | 2023-03-07 | 江苏先声药业有限公司 | 一种含依匹哌唑药物组合物及其制备方法 |
CN112656767A (zh) * | 2021-01-22 | 2021-04-16 | 烟台东诚药业集团股份有限公司 | 一种依诺肝素钠注射制剂及其制备方法 |
EP4043008A1 (en) | 2021-02-15 | 2022-08-17 | Warszawskie Zaklady Farmaceutyczne Polfa S.A. | Method for the preparation of a pharmaceutical composition comprising aripiprazole |
WO2023083212A1 (zh) * | 2021-11-10 | 2023-05-19 | 广东东阳光药业有限公司 | 一种喹啉类药物的组合物 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5006528A (en) | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
GB9105705D0 (en) | 1991-03-18 | 1991-05-01 | Sandoz Ltd | Improvements in or relating to organic compounds |
ATE288270T1 (de) | 1993-11-19 | 2005-02-15 | Janssen Pharmaceutica Nv | Mikroverkapselte 1,2-benzazole |
GB9718986D0 (en) | 1997-09-09 | 1997-11-12 | Danbiosyst Uk | Controlled release microsphere delivery system |
US7521068B2 (en) * | 1998-11-12 | 2009-04-21 | Elan Pharma International Ltd. | Dry powder aerosols of nanoparticulate drugs |
MY129350A (en) * | 2001-04-25 | 2007-03-30 | Bristol Myers Squibb Co | Aripiprazole oral solution |
AR033485A1 (es) | 2001-09-25 | 2003-12-26 | Otsuka Pharma Co Ltd | Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma |
US20050019607A1 (en) | 2003-06-30 | 2005-01-27 | Franky So | OLED device with mixed emissive layer |
US20050032811A1 (en) * | 2003-08-06 | 2005-02-10 | Josiah Brown | Methods for administering aripiprazole |
MXPA06004489A (es) * | 2003-10-23 | 2006-06-20 | Otsuka Pharma Co Ltd | Formulacion y metodo de aripiprazol inyectable esteril de liberacion controlada. |
TWI371274B (en) | 2003-10-23 | 2012-09-01 | Bristol Myers Squibb Co | Process for making sterile aripiprazole of desired mean particle size |
EP1732107A4 (en) | 2004-03-30 | 2009-05-13 | Fujitsu Microelectronics Ltd | METHOD FOR CORRECTING EXPOSURE DATA TO AN ELECTRON BEAM |
US7731873B2 (en) | 2005-08-09 | 2010-06-08 | Coopervision International Holding Company, Lp | Contact lens mold assemblies and systems and methods of producing same |
JP2009508859A (ja) * | 2005-09-15 | 2009-03-05 | エラン ファーマ インターナショナル リミテッド | ナノ粒子アリピプラゾール製剤 |
HUE036214T2 (hu) * | 2007-07-31 | 2018-06-28 | Otsuka Pharma Co Ltd | Eljárások aripiprazol-szuszpenzió és fagyasztva szárított készítmény elõállítására |
-
2012
- 2012-06-03 JO JOP/2012/0141A patent/JO3410B1/ar active
- 2012-06-06 AR ARP120101990A patent/AR086682A1/es not_active Application Discontinuation
- 2012-06-06 TW TW101120275A patent/TWI519320B/zh active
- 2012-06-07 MY MYPI2013702194A patent/MY166052A/en unknown
- 2012-06-07 EA EA201391818A patent/EA023951B1/ru not_active IP Right Cessation
- 2012-06-07 EP EP12731189.2A patent/EP2717859B1/en active Active
- 2012-06-07 BR BR112013031459-1A patent/BR112013031459B1/pt active IP Right Grant
- 2012-06-07 ES ES12731189.2T patent/ES2599479T3/es active Active
- 2012-06-07 WO PCT/JP2012/065180 patent/WO2012169662A1/en active Application Filing
- 2012-06-07 US US14/124,459 patent/US11154507B2/en active Active
- 2012-06-07 CN CN201610937357.1A patent/CN106389357A/zh active Pending
- 2012-06-07 PT PT127311892T patent/PT2717859T/pt unknown
- 2012-06-07 CA CA2837693A patent/CA2837693C/en active Active
- 2012-06-07 HU HUE12731189A patent/HUE031723T2/hu unknown
- 2012-06-07 LT LTEP12731189.2T patent/LT2717859T/lt unknown
- 2012-06-07 KR KR1020147000021A patent/KR102014124B1/ko active IP Right Grant
- 2012-06-07 CN CN201810450421.2A patent/CN108379231A/zh active Pending
- 2012-06-07 SI SI201230741A patent/SI2717859T1/sl unknown
- 2012-06-07 SG SG2013085568A patent/SG195046A1/en unknown
- 2012-06-07 MX MX2013014186A patent/MX354473B/es active IP Right Grant
- 2012-06-07 CN CN201280027909.5A patent/CN103596557A/zh active Pending
- 2012-06-07 PL PL12731189T patent/PL2717859T3/pl unknown
- 2012-06-07 AU AU2012267810A patent/AU2012267810B2/en active Active
- 2012-06-07 JP JP2013554727A patent/JP6012637B2/ja active Active
- 2012-06-07 DK DK12731189.2T patent/DK2717859T3/en active
- 2012-07-06 UA UAA201315553A patent/UA112186C2/uk unknown
-
2013
- 2013-11-17 IL IL229467A patent/IL229467A/en active IP Right Grant
- 2013-11-19 ZA ZA2013/08868A patent/ZA201308868B/en unknown
- 2013-12-30 CO CO13302836A patent/CO6842019A2/es unknown
-
2014
- 2014-05-14 HK HK14104543.8A patent/HK1191245A1/zh unknown
-
2016
- 2016-10-18 HR HRP20161357TT patent/HRP20161357T1/hr unknown
- 2016-11-03 CY CY20161101125T patent/CY1118561T1/el unknown
-
2021
- 2021-09-24 US US17/448,862 patent/US20220008341A1/en not_active Abandoned
- 2021-11-29 AR ARP210103281A patent/AR124163A2/es unknown
-
2023
- 2023-10-09 US US18/483,098 patent/US20240041774A1/en active Pending
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