JO3753B1 - قرص يتألف من 7-[4-(4-بينزو[بي]ثيوفين-4-ايل-ببرازين-1-1ايل)بوتكسيل]-1اتش-كوينولين-2-وان أو ملح منه - Google Patents

قرص يتألف من 7-[4-(4-بينزو[بي]ثيوفين-4-ايل-ببرازين-1-1ايل)بوتكسيل]-1اتش-كوينولين-2-وان أو ملح منه

Info

Publication number
JO3753B1
JO3753B1 JOP/2012/0301A JOP20120301A JO3753B1 JO 3753 B1 JO3753 B1 JO 3753B1 JO P20120301 A JOP20120301 A JO P20120301A JO 3753 B1 JO3753 B1 JO 3753B1
Authority
JO
Jordan
Prior art keywords
quinolin
thiophen
piperazin
benzo
butoxy
Prior art date
Application number
JOP/2012/0301A
Other languages
English (en)
Inventor
Inoue Yoshiharu
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48081918&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JO3753(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of JO3753B1 publication Critical patent/JO3753B1/ar

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2813—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Supply Of Fluid Materials To The Packaging Location (AREA)
  • Basic Packing Technique (AREA)

Abstract

يتعلق ذلك الاختراع بقرص يتضمن، كمكون أساسي نشط، 7-<span dir="LTR">]</span>4-(4-بنزو<span dir="LTR"> [b] </span>ثيوفين-4-يل-بيبرازين-1-يل)بيوتوكسي<span dir="LTR">[</span>-1<span dir="LTR">H</span>-كينولين-2- أون أو ملح منه، يكون له قابلية تقتت ممتازة، استقرار أثناء التخزين و الاستقرار الضوئي. <span dir="RTL">يحتوي القرص الخاص بالاختراع الحالي على 7-</span>]<span dir="RTL">4-(4- بنزو </span>[b] <span dir="RTL">ثيوفين-4-يل- بيبرازين-1-يل) بيوتوكسي</span>[<span dir="RTL">-1</span>H<span dir="RTL">-كينولين-2- أون أو ملح منه كمكون أساسي نش، و يحتوي أيضا على عامل تغطية تتضمن لاكتوز، نشا الذرة، بلورة سيلولوز دقيقة و سواغات مشابهة؛ هيدروكسي بروبيل سيلولوز منخفض الاستبدال، كروسكارميلوز صوديوم، صوديوم كربوكسيل ميثيل نشا و مواد مفتتة مشابهة؛ هيدروكسي بروبيل سيلولوز و مواد رابطو مشابهة؛ ميلوز فائق؛تلك؛ أكسيد تيتانيوم؛ مواد ملونة؛ و ما شابه ذلك.</span>
JOP/2012/0301A 2011-10-14 2012-10-04 قرص يتألف من 7-[4-(4-بينزو[بي]ثيوفين-4-ايل-ببرازين-1-1ايل)بوتكسيل]-1اتش-كوينولين-2-وان أو ملح منه JO3753B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011227057 2011-10-14

Publications (1)

Publication Number Publication Date
JO3753B1 true JO3753B1 (ar) 2021-01-31

Family

ID=48081918

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2012/0301A JO3753B1 (ar) 2011-10-14 2012-10-04 قرص يتألف من 7-[4-(4-بينزو[بي]ثيوفين-4-ايل-ببرازين-1-1ايل)بوتكسيل]-1اتش-كوينولين-2-وان أو ملح منه

Country Status (34)

Country Link
US (8) US20140234417A1 (ar)
EP (1) EP2767285B2 (ar)
JP (2) JP6084161B2 (ar)
KR (1) KR102072371B1 (ar)
CN (2) CN103889425B (ar)
AP (1) AP2014007564A0 (ar)
AR (1) AR088319A1 (ar)
AU (1) AU2012321723C1 (ar)
BR (1) BR112014008603A2 (ar)
CA (1) CA2851588C (ar)
CL (1) CL2014000909A1 (ar)
CO (1) CO6950480A2 (ar)
CY (1) CY1122460T1 (ar)
DK (1) DK2767285T4 (ar)
EA (1) EA032930B1 (ar)
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HR (1) HRP20200037T4 (ar)
HU (1) HUE047493T2 (ar)
IL (1) IL231513B (ar)
IN (1) IN2014DN02055A (ar)
JO (1) JO3753B1 (ar)
LT (1) LT2767285T (ar)
MX (1) MX376092B (ar)
MY (1) MY173370A (ar)
PH (1) PH12014500607A1 (ar)
PL (1) PL2767285T5 (ar)
PT (1) PT2767285T (ar)
SG (2) SG10201608412SA (ar)
SI (1) SI2767285T2 (ar)
TW (1) TWI634908B (ar)
UA (1) UA114411C2 (ar)
WO (1) WO2013054872A1 (ar)
ZA (1) ZA201402333B (ar)

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JP6084161B2 (ja) 2017-02-22
PT2767285T (pt) 2020-01-21
AU2012321723C1 (en) 2017-11-02
IL231513B (en) 2020-01-30
US20160158227A1 (en) 2016-06-09
DK2767285T3 (da) 2020-01-27
SG2014013783A (en) 2014-06-27
JP2017088610A (ja) 2017-05-25
NZ622639A (en) 2015-11-27
ES2762479T3 (es) 2020-05-25
EA201490783A1 (ru) 2014-07-30
IN2014DN02055A (ar) 2015-05-15
ZA201402333B (en) 2015-07-29
PL2767285T3 (pl) 2020-04-30
TWI634908B (zh) 2018-09-11
EP2767285B1 (en) 2019-11-27
KR20140075754A (ko) 2014-06-19
US20180008600A1 (en) 2018-01-11
EP2767285B2 (en) 2025-02-19
CL2014000909A1 (es) 2014-11-21
US10307419B2 (en) 2019-06-04
MX376092B (es) 2025-03-07
CA2851588A1 (en) 2013-04-18
KR102072371B1 (ko) 2020-02-03
CN107397730A (zh) 2017-11-28
EA032930B1 (ru) 2019-08-30
US20240277703A1 (en) 2024-08-22
AU2012321723A1 (en) 2014-05-15
BR112014008603A2 (pt) 2017-04-18
WO2013054872A1 (ja) 2013-04-18
IL231513A0 (en) 2014-04-30
HRP20200037T1 (hr) 2020-03-20
PL2767285T5 (pl) 2025-06-02
SI2767285T1 (sl) 2020-03-31
CN103889425A (zh) 2014-06-25
US20140234417A1 (en) 2014-08-21
CN103889425B (zh) 2018-08-03
TW201318651A (zh) 2013-05-16
AP2014007564A0 (en) 2014-04-30
CY1122460T1 (el) 2021-01-27
US20210023078A1 (en) 2021-01-28
AR088319A1 (es) 2014-05-28
MY173370A (en) 2020-01-21
HRP20200037T4 (hr) 2025-05-23
CA2851588C (en) 2019-07-02
EP2767285A4 (en) 2015-03-11
PH12014500607A1 (en) 2014-04-21
JPWO2013054872A1 (ja) 2015-03-30
US20190240215A1 (en) 2019-08-08
LT2767285T (lt) 2020-02-10
ES2762479T5 (en) 2025-05-30
US20170165258A1 (en) 2017-06-15
DK2767285T4 (da) 2025-04-22
UA114411C2 (uk) 2017-06-12
FI2767285T4 (fi) 2025-05-08
SG10201608412SA (en) 2016-12-29
MX2014004135A (es) 2014-07-24
HUE047493T2 (hu) 2020-04-28
SI2767285T2 (sl) 2025-06-30
EP2767285A1 (en) 2014-08-20
US20220331311A1 (en) 2022-10-20
CO6950480A2 (es) 2014-05-20
AU2012321723B2 (en) 2017-07-20

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