CY1122460T1 - ΔΙΣΚΙΟ ΠΟΥ ΠΕΡΙΛΑΜΒΑΝΕΙ 7- [4- (4-ΒΕΝΖΟ [b] ΘΕΙΟΦΑΙΝ-4-ΥΛΟ-ΠΙΠΕΡΑΖΙΝ-1-ΥΛΟ)ΒΟΥΤΟΞΥ]-1Η-ΚΙΙΝΟΛΙΝ-2-ΟΝΗ Ή ΑΛΑΣ ΑΥΤΗΣ - Google Patents
ΔΙΣΚΙΟ ΠΟΥ ΠΕΡΙΛΑΜΒΑΝΕΙ 7- [4- (4-ΒΕΝΖΟ [b] ΘΕΙΟΦΑΙΝ-4-ΥΛΟ-ΠΙΠΕΡΑΖΙΝ-1-ΥΛΟ)ΒΟΥΤΟΞΥ]-1Η-ΚΙΙΝΟΛΙΝ-2-ΟΝΗ Ή ΑΛΑΣ ΑΥΤΗΣInfo
- Publication number
- CY1122460T1 CY1122460T1 CY20201100009T CY201100009T CY1122460T1 CY 1122460 T1 CY1122460 T1 CY 1122460T1 CY 20201100009 T CY20201100009 T CY 20201100009T CY 201100009 T CY201100009 T CY 201100009T CY 1122460 T1 CY1122460 T1 CY 1122460T1
- Authority
- CY
- Cyprus
- Prior art keywords
- thiophen
- piperazin
- benzo
- butoxy
- salt
- Prior art date
Links
- ZKIAIYBUSXZPLP-UHFFFAOYSA-N brexpiprazole Chemical compound C1=C2NC(=O)C=CC2=CC=C1OCCCCN(CC1)CCN1C1=CC=CC2=C1C=CS2 ZKIAIYBUSXZPLP-UHFFFAOYSA-N 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000011247 coating layer Substances 0.000 abstract 2
- 229920002261 Corn starch Polymers 0.000 abstract 1
- 229920002785 Croscarmellose sodium Polymers 0.000 abstract 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 235000019759 Maize starch Nutrition 0.000 abstract 1
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 1
- 229920002472 Starch Polymers 0.000 abstract 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 abstract 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 229960001681 croscarmellose sodium Drugs 0.000 abstract 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000007884 disintegrant Substances 0.000 abstract 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 abstract 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- 229960003943 hypromellose Drugs 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 229940031703 low substituted hydroxypropyl cellulose Drugs 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 1
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 1
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000000049 pigment Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229940083542 sodium Drugs 0.000 abstract 1
- 235000015424 sodium Nutrition 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
- 239000000454 talc Substances 0.000 abstract 1
- 229910052623 talc Inorganic materials 0.000 abstract 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2813—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Αυτή η εφεύρεση σχετίζεται με ένα δισκίο που περιέχει, ως δραστικό συστατικό, 7-[4-(4-βενζο[b]θειοφαιν-4-υλο-πιπεραζιν-1-υλο) βουτοξυ]-1Η-κινολιν-2-όνη ή ένα άλας αυτής, που έχει εξαιρετική ικανότητα αποσάθρωσης, σταθερότητα αποθήκευσης και φωτοσταθερότητα. Το δισκίο της παρούσας εφεύρεσης που περιλαμβάνει ένα μη επικαλυμμένο δισκίο που περιέχει 7-[4-(4-βενζο[b]θειοφαιν-4-υλο-πιπεραζιν-1-υλο) βουτοξυ]-1Η-κινολιν-2-όνη ή ένα άλας αυτής ως δραστικό συστατικό, έκδοχα όπως λακτόζη, άμυλο αραβοσίτου και μικροκρυσταλλική κυτταρίνη• αποσαθρωτικά όπως χαμηλής υποκατάστασης υδροξυπροπυλοκυτταρίνη, νατριούχο κροσκαρμελλόζη και νατριούχο καρβοξυμεθυλικό άμυλο• συνδετικά υλικά όπως υδροξυπροπυλοκυτταρίνη• λιπαντικά όπως στεατικό• και που περιλαμβάνει επιπλέον μια στιβάδα επικάλυψης που περιέχει υπρομελλόζη• τάλκη• οξείδιο του τιτανίου• χρωστική• και τα παρόμοια, όπου η στιβάδα επικάλυψης εφαρμόζεται στην επιφάνεια του μη επικαλυμμένου δισκίου.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2011227057 | 2011-10-14 | ||
PCT/JP2012/076415 WO2013054872A1 (ja) | 2011-10-14 | 2012-10-12 | 7-[4-(4-ベンゾ[b]チオフェン-4-イル-ピペラジン-1-イル)ブトキシ]-1H-キノリン-2-オン又はその塩を含む錠剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1122460T1 true CY1122460T1 (el) | 2021-01-27 |
Family
ID=48081918
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20201100009T CY1122460T1 (el) | 2011-10-14 | 2020-01-08 | ΔΙΣΚΙΟ ΠΟΥ ΠΕΡΙΛΑΜΒΑΝΕΙ 7- [4- (4-ΒΕΝΖΟ [b] ΘΕΙΟΦΑΙΝ-4-ΥΛΟ-ΠΙΠΕΡΑΖΙΝ-1-ΥΛΟ)ΒΟΥΤΟΞΥ]-1Η-ΚΙΙΝΟΛΙΝ-2-ΟΝΗ Ή ΑΛΑΣ ΑΥΤΗΣ |
Country Status (32)
Country | Link |
---|---|
US (7) | US20140234417A1 (el) |
EP (1) | EP2767285B1 (el) |
JP (2) | JP6084161B2 (el) |
KR (1) | KR102072371B1 (el) |
CN (2) | CN103889425B (el) |
AP (1) | AP2014007564A0 (el) |
AR (1) | AR088319A1 (el) |
AU (1) | AU2012321723C1 (el) |
BR (1) | BR112014008603A2 (el) |
CA (1) | CA2851588C (el) |
CL (1) | CL2014000909A1 (el) |
CO (1) | CO6950480A2 (el) |
CY (1) | CY1122460T1 (el) |
DK (1) | DK2767285T3 (el) |
EA (1) | EA032930B1 (el) |
ES (1) | ES2762479T3 (el) |
HR (1) | HRP20200037T1 (el) |
HU (1) | HUE047493T2 (el) |
IL (1) | IL231513B (el) |
IN (1) | IN2014DN02055A (el) |
JO (1) | JO3753B1 (el) |
LT (1) | LT2767285T (el) |
MX (1) | MX2014004135A (el) |
MY (1) | MY173370A (el) |
PL (1) | PL2767285T3 (el) |
PT (1) | PT2767285T (el) |
SG (2) | SG10201608412SA (el) |
SI (1) | SI2767285T1 (el) |
TW (1) | TWI634908B (el) |
UA (1) | UA114411C2 (el) |
WO (1) | WO2013054872A1 (el) |
ZA (1) | ZA201402333B (el) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
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TWI320783B (en) | 2005-04-14 | 2010-02-21 | Otsuka Pharma Co Ltd | Heterocyclic compound |
JO3753B1 (ar) * | 2011-10-14 | 2021-01-31 | Otsuka Pharma Co Ltd | قرص يتألف من 7-[4-(4-بينزو[بي]ثيوفين-4-ايل-ببرازين-1-1ايل)بوتكسيل]-1اتش-كوينولين-2-وان أو ملح منه |
JOP20200109A1 (ar) | 2012-04-23 | 2017-06-16 | Otsuka Pharma Co Ltd | مستحضر قابل للحقن |
JP5936732B1 (ja) * | 2015-03-05 | 2016-06-22 | 日本カラコン合同会社 | フィルムコーティング組成物 |
CN105106142B (zh) * | 2015-09-22 | 2018-05-22 | 成都欣捷高新技术开发有限公司 | 一种含有依匹哌唑的冻干口服制剂及其制备方法 |
CN106994119A (zh) * | 2016-01-22 | 2017-08-01 | 浙江华海药业股份有限公司 | 含有依匹哌唑或其盐的口腔崩解片及其制备方法 |
CA3014090A1 (en) * | 2016-02-19 | 2017-08-24 | Jiangsu Hengrui Medicine Co., Ltd. | Pharmaceutical composition containing jak kinase inhibitor or pharmaceutically acceptable salt thereof |
US20190201345A1 (en) * | 2016-06-28 | 2019-07-04 | Japan Antivirus Res. Inst., Ltd. | Excipient and tablet |
JP7060878B2 (ja) * | 2016-07-27 | 2022-04-27 | 日本臓器製薬株式会社 | メトトレキサート含有フィルムコーティング錠 |
WO2018033484A1 (en) | 2016-08-16 | 2018-02-22 | Hexal Aktiengesellschaft | Pharmaceutical compositions of a benzothiophene compound |
US11123300B2 (en) * | 2016-08-16 | 2021-09-21 | Hexal Ag | Immediate release tablet of a benzothiophene compound |
CN106496206A (zh) * | 2016-08-31 | 2017-03-15 | 安徽省润生医药股份有限公司 | 一种依匹哌唑新的制备方法 |
CN110325193B (zh) * | 2017-02-23 | 2023-05-05 | 勃林格殷格翰国际有限公司 | 化合物iii的新型医学用途 |
JP7166754B2 (ja) * | 2017-11-22 | 2022-11-08 | 沢井製薬株式会社 | ダサチニブ無水物含有製剤 |
EP3501506B1 (en) | 2017-12-19 | 2019-10-09 | Alfred E. Tiefenbacher (GmbH & Co. KG) | Pharmaceutical tablet composition comprising brexpiprazole |
EP3545950A1 (en) | 2018-03-26 | 2019-10-02 | Adamed sp. z o.o. | Pharmaceutical composition comprising brexpiprazole |
JPWO2021029020A1 (el) * | 2019-08-13 | 2021-02-18 | ||
CN112168794A (zh) * | 2020-10-27 | 2021-01-05 | 浙江诺得药业有限公司 | 一种布瑞哌唑片的制备方法 |
CN115192549A (zh) * | 2021-04-13 | 2022-10-18 | 上海博志研新药物技术有限公司 | 一种布瑞哌唑物口腔薄膜剂、其制备方法及应用 |
Family Cites Families (22)
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US6562375B1 (en) * | 1999-08-04 | 2003-05-13 | Yamanouchi Pharmaceuticals, Co., Ltd. | Stable pharmaceutical composition for oral use |
WO2003055467A1 (en) * | 2001-12-18 | 2003-07-10 | Synthon B.V. | Simvastatin dosage forms |
US7439251B2 (en) * | 2002-05-03 | 2008-10-21 | Israel Institute For Biological Research | Methods and compositions for treatment of central and peripheral nervous system disorders and novel compounds useful therefor |
AU2004234158B2 (en) | 2003-04-29 | 2010-01-28 | Pfizer Inc. | 5,7-diaminopyrazolo[4,3-D]pyrimidines useful in the treatment of hypertension |
CN100480279C (zh) * | 2003-06-09 | 2009-04-22 | 陶氏环球技术公司 | 稳定的有机硼烷聚合反应引发剂和可聚合的组合物 |
JP2006061067A (ja) * | 2004-08-26 | 2006-03-09 | Asahi Kasei Life & Living Corp | 酸素インジケーター |
GB0504203D0 (en) * | 2005-03-01 | 2005-04-06 | Novartis Ag | Organic compounds |
WO2006097344A1 (en) | 2005-03-17 | 2006-09-21 | Synthon B.V. | Pharmaceutical tablets of crystalline type ii aripiprazole |
TWI320783B (en) * | 2005-04-14 | 2010-02-21 | Otsuka Pharma Co Ltd | Heterocyclic compound |
JP4315393B2 (ja) * | 2005-04-14 | 2009-08-19 | 大塚製薬株式会社 | 複素環化合物 |
US8865722B2 (en) | 2006-01-05 | 2014-10-21 | Teva Pharmaceutical Industries Ltd. | Wet formulations of aripiprazole |
JP4806595B2 (ja) * | 2006-07-05 | 2011-11-02 | 富士フイルム株式会社 | 固体撮像素子駆動装置及びデジタルカメラ |
JP4540700B2 (ja) * | 2006-10-13 | 2010-09-08 | 大塚製薬株式会社 | 医薬 |
WO2008106059A1 (en) * | 2007-02-26 | 2008-09-04 | Merck & Co., Inc. | Formulations for cathepsin k inhibitors |
JP5432720B2 (ja) * | 2007-03-13 | 2014-03-05 | 武田薬品工業株式会社 | 2−[[6−[(3r)−3−アミノ−1−ピペリジニル]−3,4−ジヒドロ−3−メチル−2,4−ジオキソ−1(2h)−ピリミジニル]メチル]−4−フルオロベンゾニトリルを含む固形製剤 |
WO2008140052A1 (ja) * | 2007-05-11 | 2008-11-20 | Santen Pharmaceutical Co., Ltd. | ロピニロール又はその塩を有効成分として含有する後眼部疾患の予防又は治療剤 |
AU2008309385B2 (en) * | 2007-10-12 | 2011-10-20 | Astrazeneca Ab | Zibotentan composition containing mannitol and/or microcrystalline cellulose |
JP5463564B2 (ja) * | 2009-05-22 | 2014-04-09 | 国立大学法人信州大学 | 耐熱性及び耐塩性セルラーゼ製剤 |
TR201000948A1 (tr) | 2010-02-09 | 2011-08-22 | Sanovel İlaç San.Ve Ti̇c.A.Ş. | Aripiprazol formülasyonları. |
AR085840A1 (es) * | 2011-04-05 | 2013-10-30 | Otsuka Pharma Co Ltd | Medicamento que contiene un compuesto que es 7-[4-(4-benzo[b]tiofen-4-il-piperazin-1-il)butoxi]-1h-quinolin-2-ona |
WO2012137071A2 (en) | 2011-04-06 | 2012-10-11 | Biovaxim Limited | Pharmaceutical compositions for preventing and/or treating an hiv disease in humans |
JO3753B1 (ar) * | 2011-10-14 | 2021-01-31 | Otsuka Pharma Co Ltd | قرص يتألف من 7-[4-(4-بينزو[بي]ثيوفين-4-ايل-ببرازين-1-1ايل)بوتكسيل]-1اتش-كوينولين-2-وان أو ملح منه |
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2012
- 2012-10-04 JO JOP/2012/0301A patent/JO3753B1/ar active
- 2012-10-09 TW TW101137267A patent/TWI634908B/zh active
- 2012-10-12 CA CA2851588A patent/CA2851588C/en active Active
- 2012-10-12 JP JP2013538582A patent/JP6084161B2/ja active Active
- 2012-10-12 CN CN201280050586.1A patent/CN103889425B/zh active Active
- 2012-10-12 AR ARP120103801A patent/AR088319A1/es not_active Application Discontinuation
- 2012-10-12 PT PT128400256T patent/PT2767285T/pt unknown
- 2012-10-12 KR KR1020147010656A patent/KR102072371B1/ko active IP Right Grant
- 2012-10-12 AP AP2014007564A patent/AP2014007564A0/xx unknown
- 2012-10-12 US US14/351,325 patent/US20140234417A1/en not_active Abandoned
- 2012-10-12 EA EA201490783A patent/EA032930B1/ru active Protection Beyond IP Right Term
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