MX2013001204A - Compuesto para el tratamiento/prevencion de enfermedades inflamatorias oculares. - Google Patents

Compuesto para el tratamiento/prevencion de enfermedades inflamatorias oculares.

Info

Publication number
MX2013001204A
MX2013001204A MX2013001204A MX2013001204A MX2013001204A MX 2013001204 A MX2013001204 A MX 2013001204A MX 2013001204 A MX2013001204 A MX 2013001204A MX 2013001204 A MX2013001204 A MX 2013001204A MX 2013001204 A MX2013001204 A MX 2013001204A
Authority
MX
Mexico
Prior art keywords
prevention
treatment
compounds
inflammatory diseases
ocular inflammatory
Prior art date
Application number
MX2013001204A
Other languages
English (en)
Other versions
MX339759B (es
Inventor
Jocelyne Annat
Helene-Celine Huguet
Olivier Lacombe
Luc Lebreton
Original Assignee
Fournier Lab Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR1056290A external-priority patent/FR2963238B1/fr
Application filed by Fournier Lab Sa filed Critical Fournier Lab Sa
Publication of MX2013001204A publication Critical patent/MX2013001204A/es
Publication of MX339759B publication Critical patent/MX339759B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere al uso de los compuestos de la fórmula (I) y sus sales aceptables farmacéuticamente para el tratamiento o la prevención de enfermedades inflamatorias oculares, en particular para el tratamiento y/o prevención de la uveítis, conjuntivitis severa, síndrome de ojo seco o retinopatía diabética.
MX2013001204A 2010-07-29 2011-07-08 Compuesto para el tratamiento/prevencion de enfermedades inflamatorias oculares. MX339759B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1056290A FR2963238B1 (fr) 2010-07-29 2010-07-29 Derives de 15-desoxyspergualine pour le traitement et/ou la prevention des maladies inflammatoires oculaires
FR1152836 2011-04-01
PCT/FR2011/051639 WO2012013884A1 (fr) 2010-07-29 2011-07-08 Composes pour le traitement/la prevention des maladies inflammatoires oculaires

Publications (2)

Publication Number Publication Date
MX2013001204A true MX2013001204A (es) 2013-08-15
MX339759B MX339759B (es) 2016-06-08

Family

ID=44514307

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013001204A MX339759B (es) 2010-07-29 2011-07-08 Compuesto para el tratamiento/prevencion de enfermedades inflamatorias oculares.

Country Status (11)

Country Link
US (1) US20130190278A1 (es)
EP (1) EP2598131A1 (es)
JP (1) JP5878172B2 (es)
KR (1) KR20130099926A (es)
CN (1) CN103037857B (es)
AU (1) AU2011284589B2 (es)
BR (1) BR112013002144A2 (es)
CA (1) CA2806942C (es)
MX (1) MX339759B (es)
RU (1) RU2582609C2 (es)
WO (1) WO2012013884A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
CA2871745C (en) 2012-05-03 2023-01-24 Kala Pharmaceuticals, Inc. Pharmaceutical nanoparticles showing improved mucosal transport
JP6360039B2 (ja) 2012-05-03 2018-07-18 カラ ファーマシューティカルズ インコーポレイテッド 複数の被覆された粒子を含む組成物、医薬組成物、医薬製剤、及び当該粒子の形成方法
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
EP2956138B1 (en) 2013-02-15 2022-06-22 Kala Pharmaceuticals, Inc. Therapeutic compounds and uses thereof
ES2831625T3 (es) 2013-02-20 2021-06-09 Kala Pharmaceuticals Inc Compuestos terapéuticos y sus usos
US9688688B2 (en) 2013-02-20 2017-06-27 Kala Pharmaceuticals, Inc. Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
US9890173B2 (en) 2013-11-01 2018-02-13 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
MX355330B (es) 2013-11-01 2018-04-16 Kala Pharmaceuticals Inc Formas cristalinas de compuestos terapeuticos y sus usos.
CN105658069A (zh) * 2013-11-04 2016-06-08 贝克顿·迪金森公司 多潜能基质细胞(msc)群体的免疫调节潜力
US20170360013A1 (en) * 2014-12-02 2017-12-21 Regeneron Pharmaceuticals, Inc. Animal model for dry eye and methods of use of such animals
EP3381438B1 (en) 2015-11-24 2023-06-07 BMI Korea Co. Ltd Composition for injection of hyaluronic acid, containing hyaluronic acid derivative and dna fraction, and use thereof
EP3448359B1 (en) * 2016-04-29 2023-06-07 Laurentia Holding B.V. Liposomal corticosteroids for topical injection in inflamed lesions or areas
CA3036340A1 (en) 2016-09-08 2018-03-15 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
AU2017324713B2 (en) 2016-09-08 2020-08-13 KALA BIO, Inc. Crystalline forms of therapeutic compounds and uses thereof
KR20190051010A (ko) 2016-09-08 2019-05-14 칼라 파마슈티컬스, 인크. 치료 화합물의 결정형 및 그의 용도
RU2633349C1 (ru) * 2016-11-24 2017-10-11 Федеральное государственное автономное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации Способ определения дифференцированных показаний к срокам лечения нарушений прекорнеальной слезной пленки после лазерного in situ кератомилеза с фемтолазерным сопровождением у детей
WO2019108602A1 (en) * 2017-11-28 2019-06-06 University Of Florida Research Foundation Methods and compositions for retinal drug delivery
EP3876712B1 (en) * 2018-11-14 2024-02-14 Smilebiotek Zhuhai Limited Screening methods for treatments of intraocular diseases or disorders

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698628B1 (fr) * 1992-12-02 1995-02-17 Fournier Ind & Sante Analogues de 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
FR2716452B1 (fr) * 1994-02-24 1996-05-10 Fournier Ind & Sante Analogues de la 15-déoxyspergualine, leur procédé de préparation et leur utilisation en thérapeutique.
CA2473461C (en) * 2002-01-11 2011-11-01 Sankyo Company, Limited Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these
US20050008640A1 (en) * 2003-04-23 2005-01-13 Wendy Waegell Method of treating transplant rejection
JP2006176457A (ja) * 2004-12-24 2006-07-06 Wakamoto Pharmaceut Co Ltd 医薬用水性液状組成物

Also Published As

Publication number Publication date
CN103037857A (zh) 2013-04-10
JP2013532678A (ja) 2013-08-19
EP2598131A1 (fr) 2013-06-05
CN103037857B (zh) 2016-02-10
AU2011284589A1 (en) 2013-02-21
BR112013002144A2 (pt) 2016-05-24
MX339759B (es) 2016-06-08
RU2013108857A (ru) 2014-09-10
RU2582609C2 (ru) 2016-04-27
WO2012013884A1 (fr) 2012-02-02
CA2806942A1 (en) 2012-02-02
US20130190278A1 (en) 2013-07-25
KR20130099926A (ko) 2013-09-06
JP5878172B2 (ja) 2016-03-08
AU2011284589B2 (en) 2015-07-16
CA2806942C (en) 2019-06-25

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