CS216917B2 - Method of making the therapeutic system for the transdermal serving of the clonidine - Google Patents

Method of making the therapeutic system for the transdermal serving of the clonidine Download PDF

Info

Publication number
CS216917B2
CS216917B2 CS784601A CS460178A CS216917B2 CS 216917 B2 CS216917 B2 CS 216917B2 CS 784601 A CS784601 A CS 784601A CS 460178 A CS460178 A CS 460178A CS 216917 B2 CS216917 B2 CS 216917B2
Authority
CS
Czechoslovakia
Prior art keywords
clonidine
weight
layer
mineral oil
polyisobutene
Prior art date
Application number
CS784601A
Other languages
Czech (cs)
English (en)
Inventor
Santosh K Chandrasekaran
Siegfried Darda
Alan S Michaels
Gary W Cleary
Original Assignee
Alza Corp
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp, Boehringer Sohn Ingelheim filed Critical Alza Corp
Publication of CS216917B2 publication Critical patent/CS216917B2/cs

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2323/00—Polyalkenes
    • B32B2323/10—Polypropylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2556/00—Patches, e.g. medical patches, repair patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CS784601A 1977-07-12 1978-07-10 Method of making the therapeutic system for the transdermal serving of the clonidine CS216917B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/815,033 US4201211A (en) 1977-07-12 1977-07-12 Therapeutic system for administering clonidine transdermally

Publications (1)

Publication Number Publication Date
CS216917B2 true CS216917B2 (en) 1982-12-31

Family

ID=25216676

Family Applications (1)

Application Number Title Priority Date Filing Date
CS784601A CS216917B2 (en) 1977-07-12 1978-07-10 Method of making the therapeutic system for the transdermal serving of the clonidine

Country Status (34)

Country Link
US (1) US4201211A (fr)
JP (1) JPS5420129A (fr)
AR (1) AR218037A1 (fr)
AT (1) AT362884B (fr)
AU (1) AU512328B2 (fr)
BE (1) BE862585A (fr)
BG (1) BG29866A3 (fr)
CA (1) CA1089362A (fr)
CH (1) CH646876A5 (fr)
CS (1) CS216917B2 (fr)
DD (1) DD135566A5 (fr)
DE (1) DE2755661C2 (fr)
DK (1) DK159375C (fr)
ES (2) ES245891Y (fr)
FI (1) FI772754A (fr)
FR (1) FR2397190A1 (fr)
GB (1) GB1577259A (fr)
GR (1) GR61591B (fr)
HU (1) HU179397B (fr)
IE (1) IE46069B1 (fr)
IL (1) IL52839A (fr)
IT (1) IT1104643B (fr)
LU (1) LU78845A1 (fr)
NL (1) NL189800C (fr)
NO (1) NO772955L (fr)
NZ (1) NZ185000A (fr)
PH (1) PH16059A (fr)
PL (1) PL113984B1 (fr)
PT (1) PT67128B (fr)
RO (1) RO75336A (fr)
SE (1) SE7709731L (fr)
SU (1) SU1005650A3 (fr)
YU (1) YU41594B (fr)
ZA (1) ZA775848B (fr)

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SE7709731L (sv) 1979-01-13
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PT67128A (fr) 1977-11-01
DE2755661A1 (de) 1979-01-25
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IL52839A (en) 1979-09-30
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US4201211A (en) 1980-05-06
AT362884B (de) 1981-06-25
PT67128B (fr) 1979-03-16
ES245891Y (es) 1980-12-16
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FR2397190B1 (fr) 1982-10-15
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IE46069L (en) 1979-01-12
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