GB2133284A - Resilient pharmaceutical unit for treating mouth ulcers - Google Patents

Resilient pharmaceutical unit for treating mouth ulcers Download PDF

Info

Publication number
GB2133284A
GB2133284A GB08300405A GB8300405A GB2133284A GB 2133284 A GB2133284 A GB 2133284A GB 08300405 A GB08300405 A GB 08300405A GB 8300405 A GB8300405 A GB 8300405A GB 2133284 A GB2133284 A GB 2133284A
Authority
GB
United Kingdom
Prior art keywords
carrier
sore
active ingredients
ulcer
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB08300405A
Other versions
GB8300405D0 (en
Inventor
Arnold Richard Webster
Raymond Hamilton-Cooper
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ENGLISH GRAINS Ltd
Original Assignee
ENGLISH GRAINS Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ENGLISH GRAINS Ltd filed Critical ENGLISH GRAINS Ltd
Priority to GB08300405A priority Critical patent/GB2133284A/en
Publication of GB8300405D0 publication Critical patent/GB8300405D0/en
Publication of GB2133284A publication Critical patent/GB2133284A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays

Landscapes

  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A pharmaceutical form for treating mouth ulcers and other painful skin lesions appropriate pharmaceutically active ingredients comprises (e.g. local anaesthetic, bactericide) in a solid resilient carrier shaped into the form of a disk or wafer having a concave major surface whereby, in use, the concave-face is pressed against the sore so that the concavity is flattened, and the resilience of the carrier then maintains a pressure differential to hold the unit in position on the ulcer while the active ingredients are liberated. Specified materials are lignocaine hydrochloride and cetyl pyridinium chloride in a gelatin carrier.

Description

SPECIFICATION An improved method and means for treating sores The present invention concerns an improved method and means for treating sores, especially but not exclusively mouth ulcers. It is to be understood that the term sores as used herein includes abrasions and skin disorders of any painful kind and also aches caused by or related to the teeth.
A known method of treatment of mouth ulcers involves sucking a tablet or lozenge containing active ingredients for treating the ulcer, the hope being that the ingredients reach the ulcer in solution or suspension in the patient's saliva.
Such a method is not completely successful and is also wasteful of active ingredients in that only a small portion of the ingredients ever come into contact with the ulcer.
A marginally better method has been devised in which the ulcer is painted with a coating which dries to form a skin thereon, the skin containing the active ingredients. This method is also disadvantageous as the ulcers are often located in parts of the mouth which cannot readily be reached by the patient and the coating is often removed before the active ingredients can perform.
It is an object of the present invention to obviate or mitigate these disadvantages.
According to the present invention there is provided a method of treating sores by applying thereto a wafer-like carrier including active ingredients for use in the treatment of the sore, holding the carrier against the sore by the application of a pressure differential thereto and allowing the carrier to break down whereby the active ingredients are applied to and retained in contact with the sore.
Further according to the present invention there is provided means for treating a sore comprising a carrier formed from a resilient material which includes an active treatment medium capable of being released on break down of the carrier whilst in contact with the sore, the carrier having a face adapted, in use, to contact the sore which is concave, whereby on pressing the carrier against the sore such that the concave face tends to flatten a pressure differential is applied to the carrier to hold it in position.
Preferably the resilient material is soluble such that the active medium therein may be released or, alternatively, the said material may be meltable at body temperature to release the ingredient.
An embodiment of the present invention will now be described by way of example only.
A means for treating a mouth ulcer comprises a circular thin, wafer-like carrier with at least one concave face manufactured from gelatin such that in its manufactured form the carrier is resilient and is soluble is saliva.
The material forming the carrier is impregnated with active ingredients suitable for the treatment of mouth ulcers, for example, lignocaine hydrochloride, a local anaesthetic and cetyl pyridinium chloride.
In use the patient presses the carrier over the ulcer and surrounding skin with the concave face facing the ulcer either by use of the finger or his tongue and in view of its resilient nature.the carrier deforms to flattern the concave face. The carrier thus acts as a suction cup and adheres to the skin and ulcer under the action of the atmosphereic pressure acting thereon.
Subsequently saliva washing against the carrier causes it to dissolve and to release its active ingredients onto the ulcer.
Various modifications can be made without departing from the scope of the invention, for example the carrier could be manufactured from material such that it melts slowly at the temperature of the mouth to release the said active ingredients.
Ingredients other than those disclosed above but also suitable for treatment of sores could be incorporated in the carder.
It should be realised that whereas the abovedescribed embodiment relates to the treatment of mouth ulcers the invention is equally suitable for use in the treatment of skin sores or skin abrasions or disorders of a painful kind and also toothache which would be covered by a suitably impregnated carrier.
Claims
1. A method of treating sores (as hereinbefore defined) by applying thereto a wafer-like carrier including active ingredients for use in the treatment of the sore, holding the carrier against the sore by the application of a pressure differential thereto and allowing the carrier to break down whereby the active ingredients are applied to and retained in contact with the sore.
2. Means for treating a sore comprising a carrier formed from a resilient material which includes an active treatment medium capable of being released on breakdown of the carrier whilst in contact with the sore, the carrier having a face adapted, in use, to contact the sore which is concave, whereby on pressing the carrier against the sore such that the concave face tends to flatten a pressure differential is applied to the carrier to hold it in position.
3. Means as claimed in claim 2 in which the resilient material is soluble such that the active medium therein may be released.
4. Means as claimed in claim 2 in which the flexible material is meltable at body temperature to release the ingredient.
5. Means as claimed in any preceding claim for treating a mouth ulcer in which the carrier is manufactured from gelatin.
6. Means as claimed in any preceding claim in which the active ingredient comprises a combination of lignocaine hydrochloride, a local anaesthetic and cetyl pyridinium chloride.
7. A method of treating sores as claimed in claim 1, substantially as hereinbefore described.
**WARNING** end of DESC field may overlap start of CLMS **.

Claims (9)

**WARNING** start of CLMS field may overlap end of DESC **. SPECIFICATION An improved method and means for treating sores The present invention concerns an improved method and means for treating sores, especially but not exclusively mouth ulcers. It is to be understood that the term sores as used herein includes abrasions and skin disorders of any painful kind and also aches caused by or related to the teeth. A known method of treatment of mouth ulcers involves sucking a tablet or lozenge containing active ingredients for treating the ulcer, the hope being that the ingredients reach the ulcer in solution or suspension in the patient's saliva. Such a method is not completely successful and is also wasteful of active ingredients in that only a small portion of the ingredients ever come into contact with the ulcer. A marginally better method has been devised in which the ulcer is painted with a coating which dries to form a skin thereon, the skin containing the active ingredients. This method is also disadvantageous as the ulcers are often located in parts of the mouth which cannot readily be reached by the patient and the coating is often removed before the active ingredients can perform. It is an object of the present invention to obviate or mitigate these disadvantages. According to the present invention there is provided a method of treating sores by applying thereto a wafer-like carrier including active ingredients for use in the treatment of the sore, holding the carrier against the sore by the application of a pressure differential thereto and allowing the carrier to break down whereby the active ingredients are applied to and retained in contact with the sore. Further according to the present invention there is provided means for treating a sore comprising a carrier formed from a resilient material which includes an active treatment medium capable of being released on break down of the carrier whilst in contact with the sore, the carrier having a face adapted, in use, to contact the sore which is concave, whereby on pressing the carrier against the sore such that the concave face tends to flatten a pressure differential is applied to the carrier to hold it in position. Preferably the resilient material is soluble such that the active medium therein may be released or, alternatively, the said material may be meltable at body temperature to release the ingredient. An embodiment of the present invention will now be described by way of example only. A means for treating a mouth ulcer comprises a circular thin, wafer-like carrier with at least one concave face manufactured from gelatin such that in its manufactured form the carrier is resilient and is soluble is saliva. The material forming the carrier is impregnated with active ingredients suitable for the treatment of mouth ulcers, for example, lignocaine hydrochloride, a local anaesthetic and cetyl pyridinium chloride. In use the patient presses the carrier over the ulcer and surrounding skin with the concave face facing the ulcer either by use of the finger or his tongue and in view of its resilient nature.the carrier deforms to flattern the concave face. The carrier thus acts as a suction cup and adheres to the skin and ulcer under the action of the atmosphereic pressure acting thereon. Subsequently saliva washing against the carrier causes it to dissolve and to release its active ingredients onto the ulcer. Various modifications can be made without departing from the scope of the invention, for example the carrier could be manufactured from material such that it melts slowly at the temperature of the mouth to release the said active ingredients. Ingredients other than those disclosed above but also suitable for treatment of sores could be incorporated in the carder. It should be realised that whereas the abovedescribed embodiment relates to the treatment of mouth ulcers the invention is equally suitable for use in the treatment of skin sores or skin abrasions or disorders of a painful kind and also toothache which would be covered by a suitably impregnated carrier. Claims
1. A method of treating sores (as hereinbefore defined) by applying thereto a wafer-like carrier including active ingredients for use in the treatment of the sore, holding the carrier against the sore by the application of a pressure differential thereto and allowing the carrier to break down whereby the active ingredients are applied to and retained in contact with the sore.
2. Means for treating a sore comprising a carrier formed from a resilient material which includes an active treatment medium capable of being released on breakdown of the carrier whilst in contact with the sore, the carrier having a face adapted, in use, to contact the sore which is concave, whereby on pressing the carrier against the sore such that the concave face tends to flatten a pressure differential is applied to the carrier to hold it in position.
3. Means as claimed in claim 2 in which the resilient material is soluble such that the active medium therein may be released.
4. Means as claimed in claim 2 in which the flexible material is meltable at body temperature to release the ingredient.
5. Means as claimed in any preceding claim for treating a mouth ulcer in which the carrier is manufactured from gelatin.
6. Means as claimed in any preceding claim in which the active ingredient comprises a combination of lignocaine hydrochloride, a local anaesthetic and cetyl pyridinium chloride.
7. A method of treating sores as claimed in claim 1, substantially as hereinbefore described.
8. A means for treating sores as claimed in claim 2, substantially as hereinbefore described.
9. Any novel subject matter or combination including novel subject matter herein disclosed, whether or not within the scope of or relating to the same invention as any of the preceding claims.
GB08300405A 1983-01-07 1983-01-07 Resilient pharmaceutical unit for treating mouth ulcers Withdrawn GB2133284A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB08300405A GB2133284A (en) 1983-01-07 1983-01-07 Resilient pharmaceutical unit for treating mouth ulcers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08300405A GB2133284A (en) 1983-01-07 1983-01-07 Resilient pharmaceutical unit for treating mouth ulcers

Publications (2)

Publication Number Publication Date
GB8300405D0 GB8300405D0 (en) 1983-02-09
GB2133284A true GB2133284A (en) 1984-07-25

Family

ID=10536041

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08300405A Withdrawn GB2133284A (en) 1983-01-07 1983-01-07 Resilient pharmaceutical unit for treating mouth ulcers

Country Status (1)

Country Link
GB (1) GB2133284A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2206044A (en) * 1987-05-28 1988-12-29 Univ Belfast Unit-dose film composition for percutaneous anaesthesia and associated method
US9956211B2 (en) 2011-04-29 2018-05-01 Moberg Pharma Ab Pharmaceutical compositions comprising a local anaesthetic such as bupivacaine for local administration to the mouth or throat

Citations (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB981372A (en) * 1960-05-04 1965-01-27 Pfizer Ltd Pharmaceutical formulations for oral administration to animals
GB1083896A (en) * 1964-04-30 1967-09-20 Dunster Lab Ltd Vehicles for administering drugs
GB1108837A (en) * 1965-11-30 1968-04-03 Astra Pharma Prod Improvements in material for causing local anaesthesia
GB1142325A (en) * 1965-05-14 1969-02-05 Higham Stanley Russell Means for administering drugs
GB1145734A (en) * 1965-06-10 1969-03-19 Higham Stanley Russell Means for administering medicaments
GB1154317A (en) * 1965-06-15 1969-06-04 Higham Stanley Russell Oral Vehicle for Administering Drugs by Buccal Absorption
GB1154318A (en) * 1965-10-21 1969-06-04 Higham Stanley Russell Improvements in Vitamin B12 Compositions
GB1213295A (en) * 1967-04-27 1970-11-25 Boots Pure Drug Co Ltd Improvements in therapeutic compositions for topical application
GB1300588A (en) * 1969-12-22 1972-12-20 Scherico Ltd Antiseptic composition
GB1341999A (en) * 1970-03-24 1973-12-25 Itek Corp Gelled burn-treating solutions
GB1384537A (en) * 1971-05-20 1975-02-19 Sterling Winthrop Group Ltd Wound coverings
GB1430684A (en) * 1972-06-26 1976-03-31 Lowey H Prolonged release lozenges
GB1471013A (en) * 1973-09-13 1977-04-21 Univ Pacific Wound dressing
GB2023614A (en) * 1978-04-12 1980-01-03 Unitika Ltd Material for wound healing
GB1565775A (en) * 1978-05-11 1980-04-23 Bates W Sting and bite treatment
GB1577259A (en) * 1977-07-12 1980-10-22 Boehringer Sohn Ingelheim Adhesive skin patch for transdermal administration of clonidine
GB1594389A (en) * 1977-06-03 1981-07-30 Max Planck Gesellschaft Dressing material for wounds
GB2085299A (en) * 1980-10-09 1982-04-28 English Grains Ltd Treating sores using wafer-like carrier with active ingredients

Patent Citations (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB981372A (en) * 1960-05-04 1965-01-27 Pfizer Ltd Pharmaceutical formulations for oral administration to animals
GB1083896A (en) * 1964-04-30 1967-09-20 Dunster Lab Ltd Vehicles for administering drugs
GB1142325A (en) * 1965-05-14 1969-02-05 Higham Stanley Russell Means for administering drugs
GB1145734A (en) * 1965-06-10 1969-03-19 Higham Stanley Russell Means for administering medicaments
GB1154317A (en) * 1965-06-15 1969-06-04 Higham Stanley Russell Oral Vehicle for Administering Drugs by Buccal Absorption
GB1154318A (en) * 1965-10-21 1969-06-04 Higham Stanley Russell Improvements in Vitamin B12 Compositions
GB1108837A (en) * 1965-11-30 1968-04-03 Astra Pharma Prod Improvements in material for causing local anaesthesia
GB1213295A (en) * 1967-04-27 1970-11-25 Boots Pure Drug Co Ltd Improvements in therapeutic compositions for topical application
GB1300588A (en) * 1969-12-22 1972-12-20 Scherico Ltd Antiseptic composition
GB1341999A (en) * 1970-03-24 1973-12-25 Itek Corp Gelled burn-treating solutions
GB1384537A (en) * 1971-05-20 1975-02-19 Sterling Winthrop Group Ltd Wound coverings
GB1430684A (en) * 1972-06-26 1976-03-31 Lowey H Prolonged release lozenges
GB1471013A (en) * 1973-09-13 1977-04-21 Univ Pacific Wound dressing
GB1594389A (en) * 1977-06-03 1981-07-30 Max Planck Gesellschaft Dressing material for wounds
GB1577259A (en) * 1977-07-12 1980-10-22 Boehringer Sohn Ingelheim Adhesive skin patch for transdermal administration of clonidine
GB2023614A (en) * 1978-04-12 1980-01-03 Unitika Ltd Material for wound healing
GB1565775A (en) * 1978-05-11 1980-04-23 Bates W Sting and bite treatment
GB2085299A (en) * 1980-10-09 1982-04-28 English Grains Ltd Treating sores using wafer-like carrier with active ingredients

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2206044A (en) * 1987-05-28 1988-12-29 Univ Belfast Unit-dose film composition for percutaneous anaesthesia and associated method
US9956211B2 (en) 2011-04-29 2018-05-01 Moberg Pharma Ab Pharmaceutical compositions comprising a local anaesthetic such as bupivacaine for local administration to the mouth or throat
US10493068B2 (en) 2011-04-29 2019-12-03 Moberg Pharma Ab Pharmaceutical compositions comprising a local anaesthetic such as bupivacaine for local administration to the mouth or throat

Also Published As

Publication number Publication date
GB8300405D0 (en) 1983-02-09

Similar Documents

Publication Publication Date Title
CA2141859C (en) Biostable drug delivery system
KR880003941Y1 (en) First aid adhesive tape
ATE81023T1 (en) DEVICE FOR ADMINISTRATION OF AN ACTIVE DRUG IN THE SKIN OR MUCOUS.
JPS61279256A (en) Balloon catheter
IE830094L (en) Drug delivery device
GB2194446B (en) Wound dressing, its preparation and use
DE69132407D1 (en) AEROSOL MEDICAL FORMULATIONS
GB2231269A (en) Contraceptive device
PH25091A (en) Active stubstance-containing plaster for the controlled administration of active substances to the skin, the use thereof and a process for the controlled administration of active substances to the skin
GB2133284A (en) Resilient pharmaceutical unit for treating mouth ulcers
GB2085299A (en) Treating sores using wafer-like carrier with active ingredients
AU3217389A (en) Reservoir for controlled release of active substances, device containing it, process for producing it, and use of the device
DE3865601D1 (en) PACKAGE FOR ADMINISTRATION OF A MEDICINAL PRODUCT.
US6069293A (en) Healing pack and applicator and method
IL88808A (en) Apparatus for administering medicaments in veterinary applications
JP3581054B2 (en) Self-heating type adhesive
JPS577412A (en) Plaster
JPH0371900B2 (en)
JP3091386B2 (en) Wart removal treatment tool
JPS63119764A (en) Emergency adhesive plaster
JPS5839731Y2 (en) magnetic therapy equipment
JPS6217063Y2 (en)
CA1316782C (en) Contraceptive device
JPS60256468A (en) Germanium skin contact treating device
JPH04329951A (en) Bandage for emergency

Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)