CN112274641A - 用于杀死衰老细胞和用于治疗衰老相关疾病和病症的方法和组合物 - Google Patents

用于杀死衰老细胞和用于治疗衰老相关疾病和病症的方法和组合物 Download PDF

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Publication number
CN112274641A
CN112274641A CN202010556478.8A CN202010556478A CN112274641A CN 112274641 A CN112274641 A CN 112274641A CN 202010556478 A CN202010556478 A CN 202010556478A CN 112274641 A CN112274641 A CN 112274641A
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days
bcl
treatment
senolytic agent
administered
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CN202010556478.8A
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Chinese (zh)
Inventor
瑞米-马丁·拉伯奇
朱迪思·坎皮斯
艾伯特·黛沃洛斯
马可·德马利亚
纳撒尼尔·大卫
阿兰·菲利普·瓦赛洛特
达伦·J·贝克
本内特·G·蔡尔兹
詹姆斯·L·柯克兰德
塔马·蒂驰科尼亚
简·M·A·范德尔森
朱毅
詹尼弗·叶利谢耶夫
金载奎
全玉熙
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Johns Hopkins University
Buck Institute for Research on Aging
Unity Biotechnology Inc
Mayo Clinic in Florida
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Johns Hopkins University
Buck Institute for Research on Aging
Unity Biotechnology Inc
Mayo Clinic in Florida
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Application filed by Johns Hopkins University, Buck Institute for Research on Aging, Unity Biotechnology Inc, Mayo Clinic in Florida filed Critical Johns Hopkins University
Publication of CN112274641A publication Critical patent/CN112274641A/zh
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CN202010556478.8A 2014-01-28 2015-01-28 用于杀死衰老细胞和用于治疗衰老相关疾病和病症的方法和组合物 Pending CN112274641A (zh)

Applications Claiming Priority (23)

Application Number Priority Date Filing Date Title
US201461932711P 2014-01-28 2014-01-28
US201461932704P 2014-01-28 2014-01-28
US61/932,704 2014-01-28
US61/932,711 2014-01-28
US201461979911P 2014-04-15 2014-04-15
US61/979,911 2014-04-15
US201462002709P 2014-05-23 2014-05-23
US62/002,709 2014-05-23
US201462042708P 2014-08-27 2014-08-27
US62/042,708 2014-08-27
US201462044664P 2014-09-02 2014-09-02
US62/044,664 2014-09-02
US201462057825P 2014-09-30 2014-09-30
US201462057820P 2014-09-30 2014-09-30
US201462057828P 2014-09-30 2014-09-30
US62/057,820 2014-09-30
US62/057,828 2014-09-30
US62/057,825 2014-09-30
US201462061627P 2014-10-08 2014-10-08
US201462061629P 2014-10-08 2014-10-08
US62/061,627 2014-10-08
US62/061,629 2014-10-08
CN201580017167.1A CN106163557B (zh) 2014-01-28 2015-01-28 用于杀死衰老细胞和用于治疗衰老相关疾病和病症的方法和组合物

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CN201910589846.6A Pending CN110623956A (zh) 2014-01-28 2015-01-28 用于杀死衰老细胞和用于治疗衰老相关疾病和病症的方法和组合物
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CN201580017167.1A Expired - Fee Related CN106163557B (zh) 2014-01-28 2015-01-28 用于杀死衰老细胞和用于治疗衰老相关疾病和病症的方法和组合物

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US (19) US9993472B2 (https=)
EP (2) EP3099380B1 (https=)
JP (5) JP6688224B2 (https=)
KR (1) KR102496146B1 (https=)
CN (3) CN112274641A (https=)
AU (4) AU2015211021B2 (https=)
BR (1) BR112016017564A8 (https=)
CA (2) CA3100140C (https=)
IL (3) IL286427B2 (https=)
MX (2) MX2016009753A (https=)
NZ (1) NZ723035A (https=)
RU (1) RU2716256C2 (https=)
SG (2) SG10201805670QA (https=)
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ES2725852T3 (es) 2010-09-27 2019-09-27 Siwa Corp Eliminación selectiva de células modificadas por AGE para el tratamiento de la aterosclerosis
US8721571B2 (en) 2010-11-22 2014-05-13 Siwa Corporation Selective removal of cells having accumulated agents
US20190269675A1 (en) 2014-01-28 2019-09-05 Buck Institute for Research and Aging Treatment of parkinson's disease and other conditions caused or mediated by senescent astrocytes using small molecule senolytic agents
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IL286427B2 (en) 2014-01-28 2024-08-01 Mayo Found Medical Education & Res Inhibitors bcl-2 anti-apoptotic protein family members for treatment of non cancer pulmonary disease or an opthalmic disease
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