CN109310573B - 包括通气式药瓶转接器和通气式液体瓶转接器的双瓶转接器组合件 - Google Patents

包括通气式药瓶转接器和通气式液体瓶转接器的双瓶转接器组合件 Download PDF

Info

Publication number
CN109310573B
CN109310573B CN201780032222.3A CN201780032222A CN109310573B CN 109310573 B CN109310573 B CN 109310573B CN 201780032222 A CN201780032222 A CN 201780032222A CN 109310573 B CN109310573 B CN 109310573B
Authority
CN
China
Prior art keywords
liquid
vial
vial adapter
drug
vented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201780032222.3A
Other languages
English (en)
Other versions
CN109310573A (zh
Inventor
伊格·德仁伯格
阿米尔·列弗
乌瑞·大卫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
West Pharma Services IL Ltd
Original Assignee
West Pharma Services IL Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by West Pharma Services IL Ltd filed Critical West Pharma Services IL Ltd
Publication of CN109310573A publication Critical patent/CN109310573A/zh
Application granted granted Critical
Publication of CN109310573B publication Critical patent/CN109310573B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1406—Septums, pierceable membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2041—Separating means having removable plugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2068—Venting means
    • A61J1/2075—Venting means for external venting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2079—Filtering means
    • A61J1/2082—Filtering means for gas filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents

Abstract

与药瓶和液体瓶一起使用的双瓶转接器组合件，该双瓶转接器组合件包括通气式药瓶转接器和通气式液体瓶转接器使得液体瓶和药瓶的同时通气帮助液体内含物从液体瓶重力流动到药瓶中用于在药瓶中形成液体药物。

Description

包括通气式药瓶转接器和通气式液体瓶转接器的双瓶转接器 组合件
技术领域
本发明涉及与包含药剂的药瓶和包含液体内含物的液体瓶一起使用的双瓶转接器组合件。
技术背景
双瓶转接器组合件包括用于伸缩地安装在液体瓶上的液体瓶转接器和用于伸缩地安装在药瓶上的药瓶转接器，该双瓶转接器组合件用来与包含药剂的药瓶和包含液体内含物的液体瓶一起使用，该液体内含物用来与药瓶中的药剂混合或重构药瓶中的药物以形成液体药物。双瓶转接器组合件通常被分为以下两类型：负压类型、重力流动类型，该负压类型目的是与负压下的药瓶一起使用用来从液体瓶中正压抽取液体内含物到该药瓶中。该重力流动类型利用液体内含物从液体瓶重力流动到药瓶。前一类型通常被用于准备小的液体药物剂量，后一类型通常被用于准备大的液体药物体积，该大的液体药物体积适合用来投予几个小的液体药物剂量或用来与IV输液器一起使用。
一个典型的负压类型的双瓶转接器组合件被公开在共同拥有的美国专利号6,558,365 (Zinger等，发明名称：液体转移装置)中，其包括具有公连接头的液体瓶转接器和具有母连接头的药瓶转接器。该公连接头优选地是公鲁尔锁接头并且该母连接头优选地是母鲁尔锁接头，该母鲁尔锁接头具有用于在其上螺纹连接母鲁尔锁接头的螺纹。这样的双瓶转接器组合件从West Pharmaceutical Services,Inc.,Exton,USA可市售购得，注册商标是MIX2VIAL。
另一个典型的负压类型的双瓶转接器组合件被公开在共同拥有的美国专利号 8,684,994(Lev等人，发明名称：具有通气式装置的流体转移组合件(Fluid TransferAssembly with Venting Arrangement))中。该双瓶转接器组合件包括通气式母小瓶转接器(vented female vial adapter)和公小瓶转接器。该通气式母小瓶转接器包括通气装置，该公小瓶转接器包括用于选择性密该通气式装置的密封装置。该双瓶转接器组合件经设计使得在重构液体药剂内含物之后在负压下仅仅过滤的空气被抽到药瓶中以保证无菌条件。
具体地，该负压类型的双瓶转接器组合件要求用户将液体瓶转接器初始地伸缩地安装在液体瓶上，并且就在此之后，将药瓶转接器伸缩地安装在药瓶上，否则负压损失，从而使得该双瓶转接器组合件不可操作。负压泄漏或负压不足可能导致液体内含物从液体瓶到药瓶抽取不充分。
一个典型的重力流动类型的双瓶转接器组合件被公开在共同拥有的美国专利号8,752,598(Denenburg等人，发明名称：液体药物转移组合件)中。美国专利号8,752,598 图9显示了双瓶转接器组合件，该双瓶转接器组合件包括具有母连接头的药瓶转接器和具有用于穿刺液体瓶瓶塞和药瓶瓶塞的双腔双末端液体转移矛状物的液体瓶转接器。有利地是，该双瓶转接器组合件并不要求伸缩地安装在液体瓶和药瓶上的具体顺序，但是相比液体内含物的正压抽取，液体内含物通过双腔双末端液体转移矛状物从液体瓶到药瓶的基于重力的转移可能需要更长时间。再者，这样的双瓶转接器组合件可遭受液体内含物从液体瓶到药瓶的不完全转移。
需要双瓶转接器组合件，该双瓶转接器组合件用来促使全部液体内含物从液体瓶到药瓶的快速转移，不论药瓶是否是在负压下。
发明内容
本发明针对的是双瓶转接器组合件(Dual vial adapter assemblages)，该双瓶转接器组合件包括a)通气式药瓶转接器(vented drug vial adapter)和b)通气式液体瓶转接器 (vented liquid vial adapter)，该通气式药瓶转接器具有双腔药瓶瓶塞穿刺套管，该双腔药瓶瓶塞穿刺套管具有i)与药瓶转接器接头流体连通的液体腔和ii)通气式通气腔 (vented air lumen)，该通气式液体瓶转接器具有双腔液体瓶瓶塞穿刺套管，该双腔液体瓶瓶塞穿刺套管具有i)与液体瓶转接器接头流体连通的液体腔和ii)通气式通气腔。在该双瓶转接器组合件的安装位置，该药瓶转接器接头与该液体瓶转接器接头流体连通，使得将该液体瓶转接器初始地伸缩地安装在该液体瓶上和将该药瓶转接器初始地伸缩地安装在该药瓶上时，随后在药瓶上方设置液体瓶导致该液体瓶通过该双腔液体瓶瓶塞穿刺套管的通气式通气腔和该药瓶通过该双腔药瓶瓶塞穿刺套管的通气式通气腔的同时通气用于帮助液体内含物从该液体瓶重力流动到该药瓶，用于在该药瓶中形成液体药物。提供通气式药瓶转接器和通气式液体瓶转接器保证了全部液体内含物从液体瓶到药瓶的快速转移，不论该药瓶是否处于负压下。
在本发明的双瓶转接器组合件的一个优选实施方案中，该药瓶转接器接头是母连接头，该液体瓶转接器接头是用来与母连接头密封配合的公连接头。因此，该双瓶转接器组合件具有与迄今提到的Zinger双瓶转接器组合件类似的构造，除了它的药瓶转接器和液体瓶转接器是通气的。该公连接头优选地是公鲁尔锁接头，该母连接头优选地是母鲁尔锁接头。
在本发明的双瓶转接器组合件的其它的优选实施方案中，该药瓶转接器和该液体瓶转接器均具有公连接头和母连接头。在这样的情况下，该双瓶转接器组合件包括中间的双末端液体转移连接器，该中间的双末端液体转移连接器具有呈母连接头或公连接头形式的一对相对的连接器端。因此，这样的双瓶转接器组合件提供了液体瓶转接器和药瓶转接器同样可被伸缩地安装在药瓶或液体瓶上的优势。
本发明的双瓶转接器组合件优选地被提供在安装位置，准备用于在从合适的无菌包装中移出时直接使用。或者，该双瓶转接器组合件可要求在使用之前由用户组装。
打算用于准备大体积的液体药物用于输液目的的本发明的双瓶转接器组合件优选地包括经设计用于从小瓶快速释放的小瓶转接器，如PCT国际公开号WO 2012/150587(发明名称：小瓶转接器)所公开的。因此，通气式药瓶转接器可很容易从包含液体药物的药瓶上移除，从而暴露它的药瓶瓶塞用于IV输液装置的插入，用来向患者输注液体药剂。
附图的简要说明
为了理解本发明并且明白如何在实践中实施它，仅仅通过非限制性实施方案，参照附图，现在描述优选实施方案，其中类似的部分被做了同样标记，并且其中：
图1是根据本发明的第一优选实施方案的给药装置的示图，该给药装置包括无针注射器、药瓶、液体瓶、IV输液器以及双瓶转接器组合件；
图2是图1的双瓶转接器组合件的分解图；
图3是图1的双瓶转接器组合件沿着图1中的线A-A的纵向截面图；
图4是图1中双瓶转接器组合件沿着图1中的线A-A的纵向截面图，显示了液体内含物从液体瓶到药瓶的转移；
图5A到图5F显示了给药装置的使用；
图6是根据本发明的第二优选实施方案的双瓶转接器组合件的透视图；
图7是图6的双瓶转接器组合件的分解图；
图8是图6双瓶转接器组合件沿着图6中的线B-B的纵向截面图；
图9是根据本发明的第三优选实施方案的双瓶转接器组合件的透视图；
图10是图9的双瓶转接器组合件的分解图；以及
图11是图9的双瓶转接器组合件沿着图9中的线C-C的纵向截面图。
本发明的优选实施方案的详细描述
图1显示了输液装置5，输液装置5包括初始空的无针注射器10、药瓶20、液体瓶30、输液器40(按减小比例显示的)和药瓶转接器组合件100。无针注射器10包括具有活塞12 和公鲁尔锁接头13的针筒11。注射器10可以与其它类型的公连接头一起形成。药瓶20具有纵向的药瓶轴20A并且包括具有药瓶瓶冠22和窄直径的药瓶瓶颈23的顶部开口的药瓶瓶体21。药瓶瓶冠22是由药瓶瓶塞24密封的。药瓶瓶塞24是由铝带26密封的。药瓶20 包含呈粉末、固体或液体形式的药剂27。液体瓶30具有纵向的药瓶轴30A并且包括具有液体瓶瓶冠32和窄直径药瓶瓶颈33的顶部开口的液体瓶瓶体31。液体瓶瓶冠32是由液体瓶瓶塞34密封的。液体瓶塞34是由铝带36密封的。液体瓶30包括仅仅呈稀释剂形式或呈活性成分形式的液体内含物37。IV输液器40包括IV矛状物41、第一管子42、夹钳43、滴注室44、第二管子46、滚动夹子(roller clamp)47、公鲁尔锁接头(male Luer connector) 48和鲁尔防护物(Luer shield)49。第一管子42通常具有4.1mm x 200mm的大小，并且第二管子46通常具有4.1mm和500mm的大小。
图2和图3显示了双瓶转接器组合件100，其具有纵向的双瓶转接器组合件中心线101 并且包括通气式药瓶转接器110和通气式液体瓶转接器120。
通气式药瓶转接器110具有纵向的药瓶转接器中心线111并且包括横向的药瓶转接器顶壁112。药瓶转接器顶壁112具有直立的药瓶转接器接头113，直立的药瓶转接器接头113 优选地是由母鲁尔锁接头(female Luer connector)构成，该母鲁尔锁接头包括用于被公鲁尔锁接头螺纹配合的外部螺纹。药瓶转接器顶壁112具有相反指向的药瓶转接器裙114 用于在药瓶20上的伸缩安装。药瓶转接器顶壁112包括双腔药瓶瓶塞穿刺套管116，用于将通气式药瓶转接器110伸缩地安装在药瓶20上时穿刺药瓶瓶塞24。双腔药瓶瓶塞穿刺套管116包括与药瓶转接器接头113流体连通的液体腔117和具有在药瓶转接器顶壁112中形成的贯穿孔119的通气式通气腔118。液体腔117通常具有比通气式通气腔118宽的直径。通气式液体瓶转接器120具有纵向的液体瓶转接器中心线121并且包括横向的液体瓶转接器顶壁122。液体瓶转接器顶壁122具有直立的液体瓶转接器接头123，直立的液体瓶转接器接头123优选地是由公鲁尔锁接头(female Luer connector)构成的，用于螺纹配合在母鲁尔锁接头113上。液体瓶转接器顶壁122具有相反指向的液体瓶转接器裙124用于在液体瓶30上的伸缩安装。液体瓶转接器顶壁122包括双腔液体瓶瓶塞穿刺套管126，用于将通气式液体瓶转接器120伸缩地安装在液体瓶30上时穿刺液体瓶瓶塞34。双腔液体瓶瓶塞穿刺套管126包括与液体瓶转接器接头123流体连通的液体腔127和具有在液体瓶转接器顶壁122形成的贯穿孔129的通气式通气腔128。液体腔127通常具有比通气式通气腔 128宽的直径。液体瓶转接器120可任选地包括用于过滤进入的空气的空气过滤器。
图4显示了液体内含物从液体瓶30通过液体腔127、液体瓶转接器接头123、药瓶转接器113和液体腔117的重力流动到药瓶20，如箭头A所示。图4显示了通过经由通气式通气腔128空气被抽取到液体瓶30中(如箭头B所示)和经由通气式通气腔118空气从药瓶20中被排出(如箭头C所示)来促进的重力流动。
图5A到图5F显示了给药装置5用于在药瓶20中准备液体药物准备向患者投予的使用。图5A显示了在液体瓶30上伸缩安装通气式液体瓶转接器120，用来穿刺液体瓶30。图5B显示了连同连接的液体瓶30一起倒置双瓶转接器组合件100并且将通气式药瓶转接器110伸缩地安装在药瓶20上用来穿刺药瓶20，从而导致液体内含物从液体瓶30重力流动到药瓶20以在其中形成液体药物。图5C显示了从通气式药瓶转接器110上拧下通气式药瓶转接器120。图5D显示了将注射器10拧紧在通气式药瓶转接器110上用于从药瓶20中抽吸液体药物剂量用于向患者投予。图5E显示了通气式药瓶转接器110从药瓶20移除。图5F 显示了IV输液器40与药瓶20的连接用于向患者输送液体药物。
图6到图8显示了在结构和操作上类似双瓶转接器100的双瓶转接器200。后者200与前者100不同之处在于后者200具有与双重组件构造(dual component construction)不同的三重组件构造。后者200包括通气式小瓶转接器130、通气式小瓶转接器140和在通气式小瓶转接器130和通气式小瓶转接器140中间的双末端液体转移连接器(dual endedliquid transfer coupler)150。通气式小瓶转接器130和通气式小瓶转接器140与通气式药瓶转接器110相同并且相应地包括母鲁尔锁接头131和母鲁尔锁接头141。双末端液体转移连接器150与双重的相对的公鲁尔锁接头151和152一起形成，用于与母鲁尔接头131 和母鲁尔接头141相应的密封的互相配合。
双瓶转接器组合件200的使用与双瓶转接器组合件100相同，除了通气式小瓶转接器 130和通气式小瓶转接器140中的一个可初始地伸缩地安装在液体瓶30上并且通气式小瓶转接器130和通气式小瓶转接器140的其它可用小瓶转接器随后伸缩地安装在药瓶20上以在药瓶20中准备液体药物。在这之后，双末端液体转移连接器150和伸缩的安装在空的液体瓶30上的通气式小瓶转接器130或通气式小瓶转接器140被移除用于实现从图5C向前的使用。
图9到图11显示了在结构与操作方面类似双瓶转接器组合件200的双瓶转接器组合件 300。后者300不同前者200的区别在于后者300包括与通气式液体瓶转接器120相同的通气式小瓶转接器160和通气式小瓶转接器170，并且相应地包括公鲁尔锁接头161和公鲁尔锁接头171。相应地，后者300包括双末端液体转移连接器180，双末端液体转移连接器180与双重的相对的母鲁尔接头181和182一起形成用于与公鲁尔锁接头161和公鲁尔锁接头171相应的密封的互相配合。
双瓶转接器组合件300的使用与双瓶转接器组合件200相同，除了双末端液体转移连接器180被靠左连接到伸缩地安装在药瓶20上的通气式小瓶转接器160或通气式小瓶转接器170，药瓶20包含准备用于注射抽吸和/或输液的液体药物。
虽然本发明的具体实施方案被说明和描述了，对本领域技术人员来说，很明显，不同的其它变化和修改可以在不脱离本发明的精神和范围的情况下被做出。

Claims (4)

1.与药瓶、液体瓶和无针注射器一起使用的双瓶转接器组合件，所述药瓶具有药瓶瓶体和密封所述药瓶瓶体的药瓶瓶塞，所述药瓶包含药剂，所述液体瓶具有液体瓶瓶体和密封所述液体瓶瓶体的液体瓶瓶塞，所述液体瓶包含用来与所述药瓶中的药剂混合或重构所述药瓶中的药剂以在所述药瓶中形成液体药物的液体内含物，所述无针注射器是空的，所述双瓶转接器组合件具有纵向的双瓶转接器组合件中心线并且包括：
(a)通气式药瓶转接器，所述通气式药瓶转接器具有纵向的药瓶转接器中心线并且包括具有直立的药瓶转接器接头的横向的药瓶转接器顶壁、用于伸缩地安装在所述药瓶上的相反指向的药瓶转接器裙和用于在所述伸缩地安装所述通气式药瓶转接器在所述药瓶上时穿刺所述药瓶瓶塞的双腔药瓶瓶塞穿刺套管，所述双腔药瓶瓶塞穿刺套管具有i)与所述药瓶转接器接头流体连通的液体腔和ii)与周围环境敞开通气的通气式通气腔；和
(b)通气式液体瓶转接器，所述通气式液体瓶转接器具有纵向的液体瓶转接器中心线并且包括具有直立的液体瓶转接器接头的横向的液体瓶转接器顶壁、用于伸缩地安装在所述液体瓶上的相反指向的液体瓶转接器裙和用于在所述伸缩地安装所述通气式液体瓶转接器在所述液体瓶上时穿刺所述液体瓶瓶塞的双腔液体瓶瓶塞穿刺套管，所述双腔液体瓶瓶塞穿刺套管具有i)与所述液体瓶转接器接头流体连通的液体腔和ii)与周围环境敞开通气的通气式通气腔，
所述通气式药瓶转接器和所述通气式液体瓶转接器是作为分立的组件形成的，
组装是使得在双瓶转接器组合件的安装位置，其中所述药瓶转接器接头与所述液体瓶转接器接头连接并且与所述液体瓶转接器接头流体连通，在将所述通气式液体瓶转接器初始地伸缩地安装在所述液体瓶上和将所述通气式药瓶转接器初始地伸缩地安装在所述药瓶上时，随后的在药瓶上方设置液体瓶导致液体内含物通过所述液体瓶和所述药瓶的同时通气的帮助从所述液体瓶重力流动到所述药瓶，用于在所述药瓶中形成液体药物，所述液体瓶通过所述双腔液体瓶瓶塞穿刺套管的通气式通气腔将周围空气抽取到其中来通气，所述药瓶通过所述双腔药瓶瓶塞穿刺套管的通气式通气腔将空气从其中排到周围环境中来通气，
所述药瓶转接器从所述液体瓶转接器可拆除用于提供所述药瓶转接器接头的入口，用于实现空的无针注射器与所述药瓶转接器接头的连接，用于从所述药瓶中抽吸液体药物剂量，用于向病人给药。
2.根据权利要求1所述的组合件，其中所述液体瓶转接器接头是公连接头，并且所述药瓶转接器接头是用来与所述公连接头直接密封配合的母连接头。
3.根据权利要求1所述的组合件，所述液体瓶转接器接头和所述药瓶转接器接头中的每者都是母连接头并且所述双瓶转接器组合件进一步包括双末端液体转移连接器，所述双末端液体转移连接器具有一对呈公连接头形式的相对的连接器端用于在所述安装位置与所述液体瓶转接器接头和所述药瓶转接器接头密封地配合。
4.根据权利要求1所述的组合件，所述液体瓶转接器接头和所述药瓶转接器接头中的每者都是公连接头并且所述双瓶转接器组合件进一步包括双末端液体转移连接器，所述双末端液体转移连接器具有一对呈母连接头形式的相对的连接器端用于在所述安装位置与所述液体瓶转接器接头和所述药瓶转接器接头密封地配合。
CN201780032222.3A 2016-05-24 2017-05-11 包括通气式药瓶转接器和通气式液体瓶转接器的双瓶转接器组合件 Active CN109310573B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL245803A IL245803A0 (en) 2016-05-24 2016-05-24 Devices with two vial adapters include an aerated drug vial adapter and an aerated liquid vial adapter
IL245803 2016-05-24
PCT/IL2017/050527 WO2017203512A1 (en) 2016-05-24 2017-05-11 Dual vial adapter assemblages including vented drug vial adapter and vented liquid vial adapter

Publications (2)

Publication Number Publication Date
CN109310573A CN109310573A (zh) 2019-02-05
CN109310573B true CN109310573B (zh) 2020-08-18

Family

ID=58765880

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780032222.3A Active CN109310573B (zh) 2016-05-24 2017-05-11 包括通气式药瓶转接器和通气式液体瓶转接器的双瓶转接器组合件

Country Status (6)

Country Link
US (1) US10765604B2 (zh)
EP (1) EP3463250B1 (zh)
JP (1) JP6636182B2 (zh)
CN (1) CN109310573B (zh)
IL (2) IL245803A0 (zh)
WO (1) WO2017203512A1 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9101717B2 (en) * 2013-03-12 2015-08-11 Carefusion 303, Inc. Non-vented vial access syringe
IL254802A0 (en) 2017-09-29 2017-12-31 Medimop Medical Projects Ltd A device with two vial adapters includes two identical perforated vial adapters
WO2020148748A1 (en) * 2019-01-18 2020-07-23 West Pharma. Services IL, Ltd. Liquid transfer devices for use with intravenous (iv) bottles
WO2020157719A1 (en) 2019-01-31 2020-08-06 West Pharma. Services Il, Ltd Liquid transfer device
IL307176A (en) 2019-04-30 2023-11-01 West Pharma Services Il Ltd A fluid delivery device with a dual-canal infusion tip
EP4096615A4 (en) * 2020-01-30 2024-02-28 Yukon Medical Llc TRANSFER DEVICE WITH USER-CONTROLLED VENTILATION
USD956958S1 (en) 2020-07-13 2022-07-05 West Pharma. Services IL, Ltd. Liquid transfer device
WO2022076908A2 (en) 2020-10-09 2022-04-14 Icu Medical, Inc. Fluid transfer device and method of use for same
DE102021125666A1 (de) 2021-10-04 2023-04-06 Sfm Medical Devices Gmbh Transfervorrichtung

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000262497A (ja) * 1999-03-16 2000-09-26 Sekisui Chem Co Ltd 分注器具、分注システム及び分注方法
CN1802143A (zh) * 2003-06-06 2006-07-12 巴克斯特国际公司 重新组配装置及其使用方法
CN101588780A (zh) * 2006-12-19 2009-11-25 卡迪纳尔健康303公司 用于药瓶进出的压力平衡设备
CN102711712A (zh) * 2010-02-24 2012-10-03 麦迪麦珀医疗工程有限公司 具有通风布置的流体转移组合件
WO2013128444A1 (en) * 2012-03-02 2013-09-06 Medeq Llc Two way fluid control device
CN103585014A (zh) * 2012-07-13 2014-02-19 贝克顿·迪金森有限公司 有压力平衡和密闭药物传输系统的瓶接入装置及其用法
US8753325B2 (en) * 2010-02-24 2014-06-17 Medimop Medical Projects, Ltd. Liquid drug transfer device with vented vial adapter

Family Cites Families (782)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US247975A (en) 1881-10-04 James h
US254444A (en) 1882-02-28 Chaeles w
US62333A (en) 1867-02-26 Henry holl
US300060A (en) 1884-06-10 Isaac v
US1021681A (en) 1911-02-13 1912-03-26 John F Jennings Valve for corrosive liquids.
US1704817A (en) 1928-01-17 1929-03-12 Okadee Company Locomotive-cylinder cock
US1930944A (en) 1932-12-21 1933-10-17 Jr William L Schmitz Measuring dispenser
US2326490A (en) 1942-06-13 1943-08-10 Harold N Perelson Fluid dispenser
US2560162A (en) 1950-02-10 1951-07-10 Becton Dickinson Co Needle structure
US2748769A (en) 1953-02-24 1956-06-05 Huber Jennie Hypodermic needle
US2830587A (en) 1954-02-01 1958-04-15 Everett Samuel James Hypodermic needles
US3059643A (en) 1954-12-10 1962-10-23 Baxter Laboratories Inc Pumping apparatus
DE1064693B (de) 1956-03-08 1959-09-03 Josef Klinger Vorrichtung zum selbsttaetigen Einstechen einer Injektionsnadel
US2931668A (en) 1956-04-30 1960-04-05 Bastian Blessing Co Coupling
US2968497A (en) 1958-02-05 1961-01-17 Avro Aircraft Ltd Self-sealing coupling
US3225763A (en) 1962-06-18 1965-12-28 Chesebrough Ponds Medicinal injector
US3277893A (en) 1964-01-31 1966-10-11 Becton Dickinson Co Hypodermic projectile with barb in the cannula bevel
US3308822A (en) 1964-04-02 1967-03-14 Loretta Fontano Hypodermic needle
DE1945279U (de) 1966-07-02 1966-09-01 Gruenenthal Chemie Hilfsgeraet zur herstellung von sterilen loesungen.
FR2029242A5 (en) 1969-01-21 1970-10-16 Alriq Christian Self-perforable plug for bacteriological - culture tubes
DE1913926A1 (de) 1969-03-19 1970-09-24 Hoechst Ag Zweikammerspritze
US3757981A (en) 1969-11-24 1973-09-11 Harris R Valves and valve needle syringes
US3618637A (en) 1970-02-04 1971-11-09 Deseret Pharma Rotary mixing valve
US3788524A (en) 1971-12-22 1974-01-29 Cutter Lab Additive container
US3826261A (en) 1971-12-27 1974-07-30 Upjohn Co Vial and syringe assembly
US3782365A (en) 1973-03-13 1974-01-01 S Pinna Detector for locating veins in living bodies
US3822700A (en) 1973-03-16 1974-07-09 M Pennington Intravenous solution dispenser
US4109670A (en) 1973-05-16 1978-08-29 Slagel Roger D Combination check flow control and selector valve
US3872992A (en) 1973-08-06 1975-03-25 Pharmaco Inc Medicament vial stopper piercing and needle positioning device
US3885607A (en) 1973-11-16 1975-05-27 Richard I Peltier Device for providing fluid communication between two sealed vessels
FR2268707B1 (zh) 1974-04-26 1976-12-17 Becton Dickinson France
US3977555A (en) 1974-05-07 1976-08-31 Pharmaco, Inc. Protective safety cap for medicament vial
US3938520A (en) 1974-06-10 1976-02-17 Abbott Laboratories Transfer unit having a dual channel transfer member
US3957052A (en) 1974-09-13 1976-05-18 Medical Development Corporation Pumping-syringe
US3993063A (en) 1975-06-16 1976-11-23 Union Carbide Corporation Protective shielding assembly for use in loading a hypodermic syringe with radioactive material
US4051852A (en) 1975-06-26 1977-10-04 The Kendall Company Aspirating device
US4026128A (en) 1975-12-12 1977-05-31 Universal Textile Machine Corporation Faulty needle sensing
US4020839A (en) 1976-02-26 1977-05-03 Parke, Davis & Company Medicament-dispensing package
USD247975S (en) 1976-07-30 1978-05-23 Luther Ronald B Catheterization needle
US4210173A (en) 1976-12-06 1980-07-01 American Hospital Supply Corporation Syringe pumping system with valves
USD248568S (en) 1976-12-13 1978-07-18 Aaron Ismach Animal intradermal nozzle for jet injection device
US4121585A (en) 1977-01-24 1978-10-24 Becker Jr Karl E Anti backflow injection device
DE2714094C3 (de) 1977-03-30 1980-04-17 Bayer Ag, 5090 Leverkusen Vorrichtung zur Bestimmung des Wassergehaltes von isotropen Materialien mit Hilfe der Mikrowellenabsorption
US4187848A (en) 1977-07-18 1980-02-12 The Kendall Company Adapter assembly
US4203443A (en) 1977-12-08 1980-05-20 Abbott Laboratories Additive transfer unit with interlocking means
US4161178A (en) 1977-12-08 1979-07-17 Abbott Laboratories Additive transfer device
USD257286S (en) 1978-03-06 1980-10-07 Tronomed International, Inc. Medical valve
US4314586A (en) 1978-08-30 1982-02-09 Tronomed International, Inc. Disposable valve
US4639019A (en) 1979-06-04 1987-01-27 Baxter Travenol Laboratories, Inc. Luer connection
US4312349A (en) 1979-07-23 1982-01-26 Cohen Milton J Filter device for injectable fluid
US4296786A (en) 1979-09-28 1981-10-27 The West Company Transfer device for use in mixing a primary solution and a secondary or additive substance
US4253501A (en) 1979-11-09 1981-03-03 Ims Limited Transfer system
US4303067A (en) 1980-01-21 1981-12-01 American Hospital Supply Corporation Medical liquid bag having an improved additive port
US4328802A (en) 1980-05-14 1982-05-11 Survival Technology, Inc. Wet dry syringe package
US4376634A (en) 1980-05-30 1983-03-15 Mallinckrodt, Inc. Assay kit having syringe, dilution device and reagents within sealed container
USD267199S (en) 1980-07-17 1982-12-07 Abbott Laboratories Vial and solution container connecting device
USD268871S (en) 1980-09-18 1983-05-03 Alva Medical, Inc. Medical tubing hub for catheters or the like
USD270282S (en) 1980-10-09 1983-08-23 Abbott Laboratories Catheter insertion adapter
US4335717A (en) 1980-10-10 1982-06-22 Abbott Laboratories I.V. Administration set with retrograde volume
USD271421S (en) 1981-06-12 1983-11-15 Fetterman James W Medical valve
US4493348A (en) 1981-06-29 1985-01-15 Pur/Acc Corporation Method and apparatus for orally dispensing liquid medication
US4434823A (en) 1981-06-29 1984-03-06 American Hospital Supply Corporation Liquid transfer device
US4465471A (en) 1981-08-26 1984-08-14 Eli Lilly And Company Intravenous administration system for dry medicine
US4392850A (en) 1981-11-23 1983-07-12 Abbott Laboratories In-line transfer unit
US4458733A (en) 1982-04-06 1984-07-10 Baxter Travenol Laboratories, Inc. Mixing apparatus
US4410321A (en) 1982-04-06 1983-10-18 Baxter Travenol Laboratories, Inc. Closed drug delivery system
US4475915A (en) 1982-05-07 1984-10-09 Sloane Glenn L Holder for a syringe and an ampoule
US4588396A (en) 1982-10-22 1986-05-13 Stroebel Maurice G Apparatus for gravity feed of liquid under constant hydrostatic pressure
USD280018S (en) 1982-10-25 1985-08-06 Commonwealth Industries Syringe loading guide
US4507113A (en) 1982-11-22 1985-03-26 Derata Corporation Hypodermic jet injector
US5688254A (en) 1983-01-24 1997-11-18 Icu Medical, Inc. Medical connector
US4752292A (en) 1983-01-24 1988-06-21 Icu Medical, Inc. Medical connector
US4505709A (en) 1983-02-22 1985-03-19 Froning Edward C Liquid transfer device
US4676530A (en) 1983-04-07 1987-06-30 Warner-Lambert Company Coupling assembly for use in fluid flow systems
WO1984004673A1 (en) 1983-05-20 1984-12-06 Bengt Gustavsson A device for transferring a substance
US4778447A (en) 1983-05-20 1988-10-18 Travenol European Research & Development Center Connectors
JPS6026391U (ja) 1983-07-30 1985-02-22 株式会社ハーマン 管接続具
US4532969A (en) 1983-09-21 1985-08-06 Kwaan Hau C Fluid withdrawal and instillation device
US4573993A (en) 1983-09-29 1986-03-04 Instafil, Inc. Fluid transfer apparatus
USD284603S (en) 1983-11-25 1986-07-08 Loignon Edward G Syphon fitting
US4743243A (en) 1984-01-03 1988-05-10 Vaillancourt Vincent L Needle with vent filter assembly
IT1173370B (it) 1984-02-24 1987-06-24 Erba Farmitalia Dispositivo di sicurezza per collegare una siringa alla imboccatura di un flacone contenente un farmaco o di un tubicino per l'erogazione del farmaco della siringa
US4585446A (en) 1984-03-16 1986-04-29 Joseph Kempf Dialysis needle
US4581014A (en) 1984-04-03 1986-04-08 Ivac Corporation Fluid infusion system
US5088996A (en) 1984-04-16 1992-02-18 Kopfer Rudolph J Anti-aerosoling drug reconstitution device
US4697622A (en) 1984-06-01 1987-10-06 Parker Hannifin Corporation Passive filling device
US4588403A (en) 1984-06-01 1986-05-13 American Hospital Supply Corporation Vented syringe adapter assembly
US4604093A (en) 1984-06-12 1986-08-05 I-Flow Corporation Apparatus and method for administering multiple fluid infusions
US5113904A (en) 1984-07-13 1992-05-19 Aslanian Jerry L Flow control device for administration of intravenous fluids
US4607671A (en) 1984-08-21 1986-08-26 Baxter Travenol Laboratories, Inc. Reconstitution device
JPS6168045A (ja) 1984-09-10 1986-04-08 テルモ株式会社 医療用活栓
US4759756A (en) 1984-09-14 1988-07-26 Baxter Travenol Laboratories, Inc. Reconstitution device
US4614437A (en) 1984-11-02 1986-09-30 Dougherty Brothers Company Mixing container and adapter
USD300060S (en) 1985-02-25 1989-02-28 William Cook Europe A/S Biopsy cannula
SE8501656D0 (sv) 1985-04-03 1985-04-03 Mediplast Ab Overforingsanordning
US4721133A (en) 1985-09-26 1988-01-26 Alcon Laboratories, Inc. Multiple use valving device
US4675020A (en) 1985-10-09 1987-06-23 Kendall Mcgaw Laboratories, Inc. Connector
US4667927A (en) 1985-11-08 1987-05-26 Rao Medical Devices, Inc. Liquid flow metering device
DE3600496A1 (de) 1986-01-10 1987-07-16 Josef Magasi Punktionskanuele, deren griff sowie verfahren zu deren herstellung
US4865592A (en) 1986-02-20 1989-09-12 Becton, Dickinson And Company Container and needle assembly
US4834152A (en) 1986-02-27 1989-05-30 Intelligent Medicine, Inc. Storage receptacle sealing and transfer apparatus
US4735608A (en) 1986-05-14 1988-04-05 Del F. Kahan Apparatus for storing and reconstituting antibiotics with intravenous fluids
US5049129A (en) 1986-05-29 1991-09-17 Zdeb Brian D Adapter for passive drug delivery system
USD303013S (en) 1986-06-19 1989-08-22 Pacesetter Infusion, Ltd. Female luer connector
SE461765B (sv) 1986-07-10 1990-03-26 Haessle Ab Anordning foer frisaettning av substans
IT1201801B (it) 1986-08-04 1989-02-02 Pietro Cosmai Caricatore miscelatore per iniettori transcutanei
IE60235B1 (en) 1986-09-18 1994-06-15 Kabi Pharmacia Ab "Connector and disposable assembly utilising said connector"
US4743229A (en) 1986-09-29 1988-05-10 Collagen Corporation Collagen/mineral mixing device and method
US4683975A (en) 1986-09-30 1987-08-04 General Motors Corporation Vehicle power window control
US4797898A (en) 1986-11-21 1989-01-10 Racal Data Communications Inc. Method and apparatus for equalization of data transmission system
US4832690A (en) 1987-01-23 1989-05-23 Baxter International Inc. Needle-pierceable cartridge for drug delivery
US4729401A (en) 1987-01-29 1988-03-08 Burron Medical Inc. Aspiration assembly having dual co-axial check valves
US5041105A (en) 1987-03-03 1991-08-20 Sherwood Medical Company Vented spike connection component
US4787898A (en) 1987-05-12 1988-11-29 Burron Medical Inc. Vented needle with sideport
US4758235A (en) 1987-05-26 1988-07-19 Tu Ho C Cardiopulmonary resuscitation medication assembly
AU101237S (en) 1987-06-18 1988-09-08 Ab Astra Transfer cannula
US5178607A (en) 1987-07-31 1993-01-12 Lynn Lawrence A Blood aspiration assembly septum and blunt needle aspirator
IT211830Z2 (it) 1987-09-22 1989-05-25 Farmitalia Carl Erba S P A Dispositivo di sicurezza perl'introduzione ed il prelievo di liquidi in e da flaconi di farmaci e simili.
US4804366A (en) 1987-10-29 1989-02-14 Baxter International Inc. Cartridge and adapter for introducing a beneficial agent into an intravenous delivery system
USD314050S (en) 1987-11-27 1991-01-22 Terumo Kabushiki Kaisha Medical connector
US4919596A (en) 1987-12-04 1990-04-24 Pacesetter Infusion, Ltd. Fluid delivery control and monitoring apparatus for a medication infusion system
US5211638A (en) 1988-01-25 1993-05-18 Baxter International Inc. Pre-slit injection site
DE3804429A1 (de) 1988-02-12 1989-08-24 Schleicher & Schuell Gmbh Einmalfilter
US4932944A (en) 1988-03-09 1990-06-12 The University Of Virginia Alumni Patents Foundation Intravenous port injection and connector system
US4857062A (en) 1988-03-09 1989-08-15 Medical Parameters, Inc. Catheter introducer valve
US4931040A (en) 1988-04-13 1990-06-05 Habley Medical Technology Safety syringe having a combination needle cannula and articulating hub for retracting said cannula into a medication carpule
US4871463A (en) 1988-08-23 1989-10-03 Sepratech Vertical reaction vessel
US4898209A (en) 1988-09-27 1990-02-06 Baxter International Inc. Sliding reconstitution device with seal
US6344031B1 (en) 1989-03-22 2002-02-05 Laurel A. Novacek Safety syringe needle device with interchangeable and retractable needle platform
US5122124A (en) 1988-12-14 1992-06-16 Patco Ventures Ltd. Safety syringe needle device with interchangeable and retractable needle platform
US5301685A (en) 1989-01-10 1994-04-12 Guirguis Raouf A Method and apparatus for obtaining a cytology monolayer
US5035686A (en) 1989-01-27 1991-07-30 C. R. Bard, Inc. Catheter exchange system with detachable luer fitting
USD328788S (en) 1989-05-01 1992-08-18 Terumo Kabushiki Kaisha Connector for catheter
US5135492A (en) 1989-06-26 1992-08-04 University Of Florida Arterial/venous fluid transfer system
USD341420S (en) 1989-07-14 1993-11-16 Ivac Corporation Combined universal spike and drip chamber
US4967797A (en) 1989-08-16 1990-11-06 Manska Wayne E Tap valve
US5053015A (en) 1989-08-30 1991-10-01 The Kendall Company Locking catheter adapter
US4997430A (en) 1989-09-06 1991-03-05 Npbi Nederlands Produktielaboratorium Voor Bloedtransfusieapparatuur En Infusievloeistoffen B.V. Method of and apparatus for administering medicament to a patient
US5578015A (en) 1989-09-18 1996-11-26 Robb Pascal Patent Limited Safety syringe incorporating automatic needle holder release
AU637130B2 (en) * 1989-11-01 1993-05-20 David Bull Laboratories Pty. Ltd. Transfer and dispensing device
DK0462255T3 (da) 1990-01-08 1994-11-21 Becton Dickinson France Opbevarings- og overføringsflaske med dobbeltkammer
US5304163A (en) 1990-01-29 1994-04-19 Baxter International Inc. Integral reconstitution device
US5125915A (en) 1990-03-02 1992-06-30 Cardiopulmonics, Inc. Locking y-connector for selective attachment to exterior of medical tubing
US5061248A (en) 1990-04-04 1991-10-29 Sacco John J Injection port safety shield
US5006114A (en) 1990-04-20 1991-04-09 Rogers Bobby E Medical valve assembly
USRE38996E1 (en) 1990-04-20 2006-02-28 Becton, Dickinson And Company Needle tip cover
US5104387A (en) 1990-05-25 1992-04-14 St. Jude Medical, Inc. Bi-planar fluid control valve
US5045066A (en) 1990-06-07 1991-09-03 Smith & Nephew, Inc. Dental needle with stick resistant protective sleeve
US5203775A (en) 1990-09-18 1993-04-20 Medex, Inc. Needleless connector sample site
US5515871A (en) 1990-09-28 1996-05-14 Sulzer Brothers Ltd. Hollow needle for medical use and a laser method for manufacturing
US5125908A (en) 1990-10-19 1992-06-30 Cohen Milton J Hypodermic syringe with protective holder
US5201717A (en) 1990-12-05 1993-04-13 Philip Wyatt Safety enclosure
US5232029A (en) 1990-12-06 1993-08-03 Abbott Laboratories Additive device for vial
US5183469A (en) 1991-05-10 1993-02-02 Becton, Dickinson And Company Device for the removal and replacement of a needle shield
DE4122221A1 (de) 1991-07-04 1993-03-18 Axel Von Brand Transfer- und entnahmespike
DE4122476A1 (de) 1991-07-06 1993-01-07 Leopold Pharma Gmbh Verfahren und vorrichtung zum ueberleiten von zwei oder mehr sterilen fluessigkeiten im geschlossenen system
US5288290A (en) 1991-09-25 1994-02-22 Alcon Surgical, Inc. Multi-ported valve assembly
US5242432A (en) 1991-09-26 1993-09-07 Ivac Needleless adapter
WO1993010001A1 (en) 1991-11-21 1993-05-27 Gds Technology, Inc. Fluid transfer device
US5171230A (en) 1991-11-29 1992-12-15 Medex, Inc. Fast flush catheter valve
US5304165A (en) 1991-12-09 1994-04-19 Habley Medical Technology Corporation Syringe-filling medication dispenser
US5247972A (en) 1991-12-17 1993-09-28 Whittier Medical, Inc. Alignment guide for hypodermic syringe
RU94030466A (ru) 1991-12-18 1996-05-20 Айку Медикал Инк. (US) Медицинский клапан, способ переливания среды, способ переливания заранее определенного количества медикаментов
US5279597A (en) 1992-01-13 1994-01-18 Arrow International Investment Corp. Catheter compression clamp
CA2093560C (en) 1992-04-10 2005-06-07 Minoru Honda Fluid container
US5328474A (en) 1992-04-13 1994-07-12 B. Braun Medical Inc. Tamper resistant syringe cap
JP2605345Y2 (ja) 1992-05-01 2000-07-10 株式会社大塚製薬工場 薬剤容器
JPH05317383A (ja) 1992-05-19 1993-12-03 Nissho Corp 薬剤容器との連通手段を備えた溶解液容器
US5279576A (en) 1992-05-26 1994-01-18 George Loo Medication vial adapter
US5232109A (en) 1992-06-02 1993-08-03 Sterling Winthrop Inc. Double-seal stopper for parenteral bottle
USD349648S (en) 1992-06-02 1994-08-16 Sterling Winthrop Inc. Closure for vials
GB9211912D0 (en) 1992-06-04 1992-07-15 Drg Flexpak Ltd Vial connector system
JPH0686738U (ja) 1992-06-16 1994-12-20 森下ルセル株式会社 医療用容器
USD357733S (en) 1992-07-28 1995-04-25 Pall Corporation Spike detector
US5300034A (en) 1992-07-29 1994-04-05 Minnesota Mining And Manufacturing Company Iv injection site for the reception of a blunt cannula
CZ29095A3 (en) 1992-08-07 1995-07-12 West Co Closing device for little containers, particularly for medicaments, for providing access without need of needle
DE9210674U1 (zh) 1992-08-07 1993-07-22 B. Braun Melsungen Ag, 34212 Melsungen, De
US5308483A (en) 1992-08-27 1994-05-03 Gelman Sciences Inc. Microporous filtration funnel assembly
US5344417A (en) 1992-09-11 1994-09-06 Becton, Dickinson And Company Universal fitting for inoculation receptacles
US5334163A (en) 1992-09-16 1994-08-02 Sinnett Kevin B Apparatus for preparing and administering a dose of a fluid mixture for injection into body tissue
US5603706A (en) 1992-09-29 1997-02-18 Wyatt; Philip Infusion apparatus
US5334179A (en) 1992-10-16 1994-08-02 Abbott Laboratories Latching piercing pin for use with fluid vials of varying sizes
US5562696A (en) 1992-11-12 1996-10-08 Cordis Innovasive Systems, Inc. Visualization trocar
US5547471A (en) 1992-11-19 1996-08-20 Baxter International Inc. In-line drug delivery device for use with a standard IV administration set and a method for delivery
US5385547A (en) 1992-11-19 1995-01-31 Baxter International Inc. Adaptor for drug delivery
US5496274A (en) 1992-11-23 1996-03-05 Becton, Dickinson And Company Locking safety needle assembly
WO1994013344A1 (fr) 1992-12-15 1994-06-23 Gabriel Meyer Dispositif pour la preparation d'une solution, d'une suspension ou d'une emulsion d'une substance medicinale
JP2604240Y2 (ja) 1992-12-25 2000-04-24 川澄化学工業株式会社 医療用具
US5405333A (en) 1992-12-28 1995-04-11 Richmond; Frank M. Liquid medicament bag with needleless connector fitting using boat assembly
JPH06239352A (ja) 1993-02-05 1994-08-30 Nissho Corp 溶解液注入セット
US5766211A (en) 1993-02-08 1998-06-16 Wood; Jan Medical device for allowing insertion and drainage into a body cavity
US5269768A (en) 1993-02-08 1993-12-14 Smiths Industries Medical Systems, Inc. Valved suction catheter
US5464111A (en) 1993-03-03 1995-11-07 Sterling Winthrop Closure for medication container
US5312377A (en) 1993-03-29 1994-05-17 Dalton Michael J Tapered luer connector
US5591143A (en) 1993-04-02 1997-01-07 Medrad Inc. Luer connector with torque indicator
US5364386A (en) 1993-05-05 1994-11-15 Hikari Seiyaku Kabushiki Kaisha Infusion unit
US5607439A (en) 1993-06-24 1997-03-04 Yoon; Inbae Safety penetrating instrument with penetrating member moving during penetration and triggered safety member protrusion
CA2124970A1 (en) 1993-06-29 1994-12-30 R. Hayes Helgren Pointed adapter for blunt entry device
US5429614A (en) 1993-06-30 1995-07-04 Baxter International Inc. Drug delivery system
US5445630A (en) 1993-07-28 1995-08-29 Richmond; Frank M. Spike with luer fitting
US5364387A (en) 1993-08-02 1994-11-15 Becton, Dickinson And Company Drug access assembly for vials and ampules
US5397303A (en) 1993-08-06 1995-03-14 River Medical, Inc. Liquid delivery device having a vial attachment or adapter incorporated therein
US5451374A (en) 1993-08-23 1995-09-19 Incutech, Inc. Medicine vessel stopper
US6146362A (en) 1993-08-27 2000-11-14 Baton Development, Inc. Needleless IV medical delivery system
BR9407390A (pt) 1993-09-07 1996-11-05 Debiotech Sa Dispositivo de seringa para mistura de dois compostos
SE9303178D0 (sv) 1993-09-29 1993-09-29 Kabi Pharmacia Ab Improvements in injection cartridges
US5806831A (en) 1993-10-13 1998-09-15 Paradis; Joseph R. Control of fluid flow with internal cannula
US5699821A (en) 1993-10-13 1997-12-23 Paradis; Joseph R. Control of fluid flow
US5509433A (en) 1993-10-13 1996-04-23 Paradis; Joseph R. Control of fluid flow
US5472022A (en) 1993-11-02 1995-12-05 Genentech, Inc. Injection pen solution transfer apparatus and method
DE4408498C2 (de) 1993-11-16 1997-06-12 Christian Eichler Umfülleinrichtung für die Medizin und die Pharmazie
US5348544A (en) 1993-11-24 1994-09-20 Becton, Dickinson And Company Single-handedly actuatable safety shield for needles
US5549577A (en) 1993-12-29 1996-08-27 Ivac Corporation Needleless connector
US5466220A (en) 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US5520659A (en) 1994-03-09 1996-05-28 Joseph K. Andonian Syringe needle cover and vial connector
US5482446A (en) 1994-03-09 1996-01-09 Baxter International Inc. Ambulatory infusion pump
US5554128A (en) 1994-03-09 1996-09-10 Joseph K. Andonian Syringe and vial connector
US5658133A (en) 1994-03-09 1997-08-19 Baxter International Inc. Pump chamber back pressure dissipation apparatus and method
US5454805A (en) 1994-03-14 1995-10-03 Brony; Seth K. Medicine vial link for needleless syringes
US5462317A (en) 1994-03-23 1995-10-31 Keller; Wilhelm A. Adapter for a mixing or dispensing device
US5527306A (en) 1994-04-18 1996-06-18 Haining; Michael L. Vial adapter
USD362718S (en) 1994-04-22 1995-09-26 Mcgaw, Inc. Turn lock cannula
DE4414697C2 (de) 1994-04-27 1998-06-18 Caremed Vertriebsgesellschaft Vorrichtung zum Transferieren und Entnehmen von Flüssigkeiten aus Flaschen, Beuteln oder ähnlichen Behältnissen für medizinische Zwecke
US5832971A (en) 1994-05-19 1998-11-10 Becton, Dickinson And Company Syringe filling and delivery device
US5746733A (en) 1994-05-19 1998-05-05 Becton, Dickinson And Company Syringe filling and delivery device
KR970703123A (ko) 1994-05-23 1997-07-03 카롤 질레스피 조성물 준비 장치(formulation preparation device)
US5649637A (en) 1994-06-02 1997-07-22 Automatic Liquid Packaging, Inc. Torque-resistant closure for a hermetically sealed container
JP3456019B2 (ja) 1994-06-17 2003-10-14 ニプロ株式会社 液体導入針およびそれを用いた乾燥製剤溶解補助具
US6183448B1 (en) 1994-06-20 2001-02-06 Bruno Franz P. Mayer Needleless injection site
US5470319A (en) 1994-06-20 1995-11-28 Critical Device Corporation Needleless injection site
DE69528063T2 (de) 1994-06-24 2003-06-05 Icu Medical Inc Vorrichtung zur überleitung einer flüssigkeit und methode zur anwendung
EP0692235A1 (en) 1994-07-14 1996-01-17 International Medication Systems (U.K.) Ltd. Mixing & dispensing apparatus
US5526853A (en) 1994-08-17 1996-06-18 Mcgaw, Inc. Pressure-activated medication transfer system
GB9419316D0 (en) 1994-09-24 1994-11-09 Robertson William F A needle guard
FR2726768A1 (fr) 1994-11-14 1996-05-15 Debiotech Sa Dispositif de seringue fixable sur un flacon
GB9425642D0 (en) 1994-12-20 1995-02-22 Weston Medical Ltd Filling device
US6681810B2 (en) 1994-12-20 2004-01-27 Aradigm Corporation Filling device for a needleless injector cartridge
US5531695A (en) 1994-12-22 1996-07-02 Sherwood Medical Company Tamper evident sleeve
US5616136A (en) 1995-01-09 1997-04-01 Med-Safe Systems, Inc. Quick release needle removal apparatus
USD369406S (en) 1995-01-13 1996-04-30 Sanofi Winthrop, Inc. Cannula
US5653686A (en) 1995-01-13 1997-08-05 Coulter Corporation Closed vial transfer method and system
US5492147A (en) 1995-01-17 1996-02-20 Aeroquip Corporation Dry break coupling
GB9501218D0 (en) 1995-01-21 1995-03-15 Boc Group Plc Medical devices
US5647845A (en) 1995-02-01 1997-07-15 Habley Medical Technology Corporation Generic intravenous infusion system
US5674195A (en) 1995-02-06 1997-10-07 Truthan; Charles Edwin Syringe apparatus and method of mixing liquid medicants within a syringe
DE19504413A1 (de) 1995-02-10 1996-08-22 Pharmacia Gmbh Überleitungsgerät
DE19506163C2 (de) 1995-02-22 1998-01-29 Hans Mueller Vorrichtung zur Behandlung von Blut
US5584819A (en) 1995-03-13 1996-12-17 Kopfer; Rudolph J. Nested blunt/sharp injection assembly
IL114960A0 (en) 1995-03-20 1995-12-08 Medimop Medical Projects Ltd Flow control device
US5651776A (en) 1995-03-22 1997-07-29 Angiodynamics, Inc. Luer-type connector
DE69603139T2 (de) 1995-04-04 1999-12-30 Kuraray Co Verfahren zur herstellung von 6-methylheptan-2-on
US5566729A (en) 1995-04-06 1996-10-22 Abbott Laboratories Drug reconstitution and administration system
DE19513666C1 (de) 1995-04-11 1996-11-28 Behringwerke Ag Vorrichtung zum Zusammenführen einer ersten flüssigen und einer zweiten festen oder flüssigen Komponente mittels Unterdruck unter sterilen Bedingungen
US5902280A (en) 1995-04-13 1999-05-11 Advanced Cytometrix, Inc. Aspiration needle apparatus incorporating its own vacuum and method and adapter for use therewith
US5562686A (en) 1995-04-19 1996-10-08 United States Surgical Corporation Apparaus and method for suturing body tissue
US5968022A (en) 1995-04-28 1999-10-19 Saito; Yoshikuni Medical hollow needle and method of production
SE509950C2 (sv) 1995-05-02 1999-03-29 Carmel Pharma Ab Anordning för administrering av toxisk vätska
US5839715A (en) 1995-05-16 1998-11-24 Alaris Medical Systems, Inc. Medical adapter having needleless valve and sharpened cannula
NZ286445A (en) 1995-05-16 1997-12-19 Ivac Corp Needleless luer connector: deformable piston occludes bore
US5685845A (en) 1995-07-11 1997-11-11 Becton, Dickinson And Company Sterile resealable vial connector assembly
US5616203A (en) 1995-07-14 1997-04-01 Merit Medical Method of manufacturing a split ring airless rotatable connector
USD388172S (en) 1995-07-27 1997-12-23 E-Z Kare Good Health Systems, Inc. Nasal dilator
JPH0956782A (ja) 1995-08-24 1997-03-04 Kanae:Kk 受動的薬剤放出用具
FR2738550B1 (fr) 1995-09-11 1997-11-07 Biodome Dispositif d'obturation d'un recipient lui-meme ferme, ensemble pour dispenser un produit comprenant un tel recipient et un tel dispositif d'obturation
IE77523B1 (en) 1995-09-11 1997-12-17 Elan Med Tech Medicament delivery device
US5702019A (en) 1995-09-27 1997-12-30 Becton Dickinson France S.A. Vial having resealable membrane assembly activated by a medical delivery device
CA2185494A1 (en) 1995-09-27 1997-03-28 Jean-Pierre Grimard Resealable vial with connector assembly having a membrane and pusher
US5989221A (en) 1995-10-20 1999-11-23 Pharmacia & Upjohn Ab Arrangement in electronically controlled injection devices
ATE233530T1 (de) 1995-10-20 2003-03-15 Schering Ag Adapter zum entnehmen einer flüssigkeit aus einem mit einem stopfen verschlossenen behältnis
US5611576A (en) 1995-11-24 1997-03-18 Industrie Borla Spa Female coupling element for haemodialysis medical equipment
US5833213A (en) 1995-12-29 1998-11-10 Rymed Technologies, Inc. Multiple dose drug vial adapter for use with a vial having a pierceable septum and a needleless syringe
ATE217181T1 (de) 1996-01-11 2002-05-15 Duoject Inc Abgabesystem für in pharmazeutischen phiolen verpackte arzneimittel
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
US6629959B2 (en) 1996-02-27 2003-10-07 Injectimed, Inc. Needle tip guard for percutaneous entry needles
US5879337A (en) 1997-02-27 1999-03-09 Injectimed, Inc. Needle tip guard for hypodermic needles
US5810792A (en) 1996-04-03 1998-09-22 Icu Medical, Inc. Locking blunt cannula
USD393722S (en) 1996-04-04 1998-04-21 Icu Medical, Inc. Locking blunt cannula
WO1997039720A1 (en) 1996-04-22 1997-10-30 Abbott Laboratories Container closure system
GB9609563D0 (en) 1996-05-08 1996-07-10 Sterimatic Holdings Ltd Venting devices
DE19619026A1 (de) 1996-05-10 1997-11-13 Trinova Gmbh Schnellkupplung
US5752942A (en) 1996-06-20 1998-05-19 Becton Dickinson And Company Five beveled point geometry for a hypodermic needle
US5897526A (en) 1996-06-26 1999-04-27 Vaillancourt; Vincent L. Closed system medication administering system
US5728087A (en) 1996-07-30 1998-03-17 Bracco Diagnostics, Inc. Universal flexible plastic container with multiple access ports of inverted Y shape configuration
US6296621B1 (en) 1996-08-23 2001-10-02 Baxter International Inc. Receptacle for passive drug delivery
CA2266033C (en) * 1996-09-10 2005-11-08 Omrix Biopharmaceuticals S.A. Applicator device for applying a multiple component fluid
US5871110A (en) 1996-09-13 1999-02-16 Grimard; Jean-Pierre Transfer assembly for a medicament container having a splashless valve
CA2211629A1 (en) 1996-09-17 1998-03-17 Bernard Sams Vial connector assembly for a medicament container
US5873872A (en) 1996-09-17 1999-02-23 Becton Dickinson And Company Multipositional resealable vial connector assembly for efficient transfer of liquid
FR2753624B1 (fr) 1996-09-25 1999-04-16 Biodome Dispositif de connexion, en particulier entre un recipient avec bouchon perforable et une seringue
US5738144A (en) 1996-10-11 1998-04-14 Aeroquip Corporation Luer connecting coupling
US5895383A (en) 1996-11-08 1999-04-20 Bracco Diagnostics Inc. Medicament container closure with recessed integral spike access means
US5817082A (en) 1996-11-08 1998-10-06 Bracco Diagnostics Inc. Medicament container closure with integral spike access means
US5941848A (en) 1996-11-14 1999-08-24 Baxter International Inc. Passive drug delivery apparatus
CA2271972C (en) 1996-11-18 2008-01-29 Andrew L. Cote, Sr. Swabbable luer-coned valve
US6883778B1 (en) 1996-11-18 2005-04-26 Nypro Inc. Apparatus for reducing fluid drawback through a medical valve
US5868710A (en) 1996-11-22 1999-02-09 Liebel Flarsheim Company Medical fluid injector
US6004278A (en) 1996-12-05 1999-12-21 Mdc Investment Holdings, Inc. Fluid collection device with retractable needle
FR2756811B1 (fr) 1996-12-06 1999-02-05 Valois Dispositif de distribution de produit fluide du type bicomposant
GB9700177D0 (en) 1997-01-07 1997-02-26 Nycomed Imaging As Container
GB9701413D0 (en) 1997-01-24 1997-03-12 Smithkline Beecham Biolog Novel device
US5954104A (en) 1997-02-28 1999-09-21 Abbott Laboratories Container cap assembly having an enclosed penetrator
US5924584A (en) 1997-02-28 1999-07-20 Abbott Laboratories Container closure with a frangible seal and a connector for a fluid transfer device
US7899511B2 (en) 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
USD405522S (en) 1997-04-18 1999-02-09 Vital Signs Inc. Breathing tube for conveying oxygen or anesthesia gas to lungs and conveying exhaled gas away from lungs of patient
US5911710A (en) 1997-05-02 1999-06-15 Schneider/Namic Medical insertion device with hemostatic valve
US6530900B1 (en) 1997-05-06 2003-03-11 Elan Pharma International Limited Drug delivery device
US5772652A (en) 1997-05-14 1998-06-30 Comar, Inc. Stab cap for a vial having a puncturable seal
US6042433A (en) 1997-05-29 2000-03-28 The Whitaker Corporation Electrical contact
JPH1147274A (ja) 1997-06-03 1999-02-23 Takeda Chem Ind Ltd ２室型注射器及び２室型注射器用接続具
IT1293856B1 (it) 1997-06-27 1999-03-10 Borla Ind Dispositivo trasduttore-protettore per linee biomedicali di emodialisi
US5755696A (en) 1997-06-30 1998-05-26 Becton, Dickinson And Company Syringe filling and delivery device
US5899468A (en) 1997-07-02 1999-05-04 Rehrig Pacific Company Organic waste cart with vented lid
US5820621A (en) 1997-07-29 1998-10-13 Becton, Dickinson And Company Medical fluid transfer and delivery device
JPH11104215A (ja) 1997-08-12 1999-04-20 Becton Dickinson Fr Sa ガラス瓶コネクタアセンブリ
US7125397B2 (en) 1997-08-20 2006-10-24 B. Braun Melsungen Ag Protective device for an injection needle
IL121605A (en) 1997-08-22 2001-03-19 Medimop Medical Projects Ltd Fluid access assembly and a method for preparing a liquid drug
US5834744A (en) 1997-09-08 1998-11-10 The Rubbright Group Tubular microwave applicator
US5919182A (en) 1997-09-12 1999-07-06 Becton, Dickinson And Company Medical fluid transfer and delivery device
US6036171A (en) 1997-09-17 2000-03-14 Halkey-Roberts Corporation Swabbable valve assembly
US6089541A (en) 1998-09-10 2000-07-18 Halkey-Roberts Corporation Valve having a valve body and a deformable stem therein
US6090093A (en) 1997-09-25 2000-07-18 Becton Dickinson And Company Connector assembly for a vial having a flexible collar
US5925029A (en) 1997-09-25 1999-07-20 Becton, Dickinson And Company Method and apparatus for fixing a connector assembly onto a vial with a crimp cap
US5944700A (en) 1997-09-26 1999-08-31 Becton, Dickinson And Company Adjustable injection length pen needle
US5935112A (en) 1997-10-15 1999-08-10 Stevens; Brian W. Hemostasis valve with catheter/guidewire seals
US5902298A (en) 1997-11-07 1999-05-11 Bracco Research Usa Medicament container stopper with integral spike access means
USD399559S (en) 1997-11-12 1998-10-13 Incutech, Inc. Pediatric catheter connector
IT236233Y1 (it) 1997-11-26 2000-08-08 Eurospital S P A Dispositivo per il collegamento di un contenitore di prodottofarmaceutico ad una sacca di prodotto liquido per effettuare il
US6019750A (en) 1997-12-04 2000-02-01 Baxter International Inc. Sliding reconstitution device with seal
US6457488B2 (en) 1998-01-08 2002-10-01 George Loo Stopcock having axial port for syringe twist actuation
US6179823B1 (en) 1998-01-20 2001-01-30 Bracco Research Usa Multiple use universal connector flexible medical container assembly
US6179822B1 (en) 1998-01-20 2001-01-30 Bracco Research Usa Single use universal access device/medical container assembly
US6186997B1 (en) 1998-01-20 2001-02-13 Bracco Research Usa Multiple use universal connector
FR2773735B1 (fr) 1998-01-20 2000-02-25 Becton Dickinson France Dispositif de confinement etanche
US6096011A (en) 1998-01-29 2000-08-01 Medrad, Inc. Aseptic connector and fluid delivery system using such an aseptic connector
US6382442B1 (en) 1998-04-20 2002-05-07 Becton Dickinson And Company Plastic closure for vials and other medical containers
US6681946B1 (en) 1998-02-26 2004-01-27 Becton, Dickinson And Company Resealable medical transfer set
US6003566A (en) 1998-02-26 1999-12-21 Becton Dickinson And Company Vial transferset and method
US6080132A (en) 1998-02-27 2000-06-27 Abbott Laboratories Apparatus for altering characteristics of a fluid
US6221065B1 (en) 1998-04-03 2001-04-24 Filtertek Inc. Self-priming needle-free “Y”-adapter
US6209738B1 (en) 1998-04-20 2001-04-03 Becton, Dickinson And Company Transfer set for vials and medical containers
US6957745B2 (en) 1998-04-20 2005-10-25 Becton, Dickinson And Company Transfer set
US6378714B1 (en) 1998-04-20 2002-04-30 Becton Dickinson And Company Transferset for vials and other medical containers
US6692478B1 (en) 1998-05-04 2004-02-17 Paradis Joseph R Swabbable needleless vial access
USD422357S (en) 1998-05-04 2000-04-04 Bracco Research Usa Stopper for medication container
US5921419A (en) 1998-05-04 1999-07-13 Bracco Research Usa Universal stopper
US6117114A (en) 1998-05-07 2000-09-12 Paradis; Joseph R. Swabbable needleless valve adaptations
USD410740S (en) 1998-05-11 1999-06-08 Incutech, Inc. Pediatric catheter connector
CA2262477C (en) 1998-05-16 2008-02-12 Bracco International B.V. Multiple use universal stopper
CN100471535C (zh) 1998-05-29 2009-03-25 劳伦斯A·林恩 路厄氏接纳器与输液的方法
US5941850A (en) 1998-06-29 1999-08-24 Shah; Binod Safety cannula
US6245044B1 (en) 1998-07-17 2001-06-12 Becton, Dickinson And Company Variable extension combined spinal/epidural needle set and method for its use
US6358236B1 (en) 1998-08-06 2002-03-19 Baxter International Inc. Device for reconstituting medicaments for injection
US6276568B1 (en) 1998-08-21 2001-08-21 Pharmacia & Upjohn Company Spray bottle grip
GB2359754B (en) 2000-03-03 2004-04-28 Nmt Group Plc Needle sheath
US6113583A (en) 1998-09-15 2000-09-05 Baxter International Inc. Vial connecting device for a sliding reconstitution device for a diluent container
US7074216B2 (en) 1998-09-15 2006-07-11 Baxter International Inc. Sliding reconstitution device for a diluent container
US20050137566A1 (en) 2003-12-23 2005-06-23 Fowles Thomas A. Sliding reconstitution device for a diluent container
AR021220A1 (es) 1998-09-15 2002-07-03 Baxter Int DISPOSITIVO DE CONEXIoN PARA ESTABLECER UNA COMUNICACIoN FLUíDA ENTRE UN PRIMER RECIPIENTE Y UN SEGUNDO RECIPIENTE.
FR2783808B1 (fr) 1998-09-24 2000-12-08 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
US6726672B1 (en) 1998-09-28 2004-04-27 Icu Medical, Inc. Intravenous drug access system
US6113068A (en) 1998-10-05 2000-09-05 Rymed Technologies Swabbable needleless injection port system having low reflux
USD430291S (en) 1998-10-08 2000-08-29 Becton, Dickinson And Company Medical container
USD431864S (en) 1998-11-24 2000-10-10 Becton Dickinson And Company Tamper evident cap for a tip cap
US6364866B1 (en) 1999-01-22 2002-04-02 Douglas Furr Syringe loading aid
USD427308S (en) 1999-01-22 2000-06-27 Medimop Medical Projects Ltd. Vial adapter
FR2789369B1 (fr) 1999-02-10 2001-04-27 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
EP1034809A1 (en) 1999-02-26 2000-09-13 F. Hoffmann-La Roche Ag Administering device for medication
USD445895S1 (en) 1999-03-05 2001-07-31 Maersk Medical A/S Funnel for a catheter
FR2790948B1 (fr) 1999-03-18 2001-06-22 Sedat Dispositif de transfert bidirectionnel d'un liquide entre un flacon et une capsule
US6099511A (en) 1999-03-19 2000-08-08 Merit Medical Systems, Inc. Manifold with check valve positioned within manifold body
USD427309S (en) 1999-04-30 2000-06-27 Incutech, Inc. Pediatric catheter connector
US6231552B1 (en) 1999-05-04 2001-05-15 Saf-T-Med, Inc. Threaded latching mechanism
US6092692A (en) 1999-05-10 2000-07-25 Riskin; Jane G. Medication applicator with incident reminder system
US6156025A (en) 1999-06-17 2000-12-05 Bracco Research Usa Inc. Twist valve
JP4329954B2 (ja) 1999-06-29 2009-09-09 東洋ゴム工業株式会社 空気入りタイヤ
US6706022B1 (en) 1999-07-27 2004-03-16 Alaris Medical Systems, Inc. Needleless medical connector with expandable valve mechanism
USD428141S (en) 1999-08-04 2000-07-11 Pharmacia & Upjohn Company Spray bottle grip
US6348044B1 (en) 1999-10-12 2002-02-19 George D. N. Coletti Method and apparatus for recapping single-use hypodermic needles
EP1237598B1 (en) 1999-10-22 2017-11-22 Antares Pharma, Inc. Medical injector and medicament loading system for use therewith
US7198618B2 (en) 1999-11-04 2007-04-03 Tyco Healthcare Group Lp Safety shield for medical needles
US6453956B2 (en) 1999-11-05 2002-09-24 Medtronic Minimed, Inc. Needle safe transfer guard
US6253804B1 (en) 1999-11-05 2001-07-03 Minimed Inc. Needle safe transfer guard
FR2800713B1 (fr) 1999-11-05 2002-01-04 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
US6632201B1 (en) 1999-11-17 2003-10-14 Baxter International Inc. Locking needle protector
US6428505B1 (en) 1999-11-19 2002-08-06 Prismedical Corporation In-line IV drug delivery pack with controllable dilution
DE19960226C1 (de) 1999-12-14 2001-05-10 Fresenius Ag Sterilitäterhaltendes Konnektionssystem für medizinische Systeme und dessen Verwendung
US6503240B1 (en) 2000-01-24 2003-01-07 Brocco Diagnostics, Inc. Vial access adapter
US6832994B2 (en) 2000-01-24 2004-12-21 Bracco Diagnostics Inc. Table top drug dispensing vial access adapter
US6139534A (en) 2000-01-24 2000-10-31 Bracco Diagnostics, Inc. Vial access adapter
US6544246B1 (en) 2000-01-24 2003-04-08 Bracco Diagnostics, Inc. Vial access adapter and vial combination
US7799009B2 (en) 2000-01-24 2010-09-21 Bracco Diagnostics Inc. Tabletop drug dispensing vial access adapter
USD445501S1 (en) 2000-01-24 2001-07-24 Bracco Diagnostics, Inc. Vial access adapter
US6706031B2 (en) 2000-02-15 2004-03-16 Comar, Inc. Needleless access apparatus and system
US20020173752A1 (en) 2000-02-16 2002-11-21 Polzin U1F Method for reconstituting an injection liquid and an injection appliance for carrying out such a method
US6530903B2 (en) 2000-02-24 2003-03-11 Xiping Wang Safety syringe
US6173868B1 (en) 2000-03-08 2001-01-16 Calmar Inc. Nasal sprayer with folding actuator
US6652509B1 (en) 2000-04-03 2003-11-25 Abbott Laboratories Housing capable of connecting a container to a medical device
JP4372310B2 (ja) 2000-04-10 2009-11-25 ニプロ株式会社 混注用アダプター
US6972002B2 (en) 2000-04-28 2005-12-06 Specialized Health Products, Inc. Passively activated safety shield for a catheter insertion needle
US6884253B1 (en) 2000-05-16 2005-04-26 Taut, Inc. Penetrating tip for trocar assembly
US6343629B1 (en) 2000-06-02 2002-02-05 Carmel Pharma Ab Coupling device for coupling a vial connector to a drug vial
US7530964B2 (en) 2000-06-30 2009-05-12 Elan Pharma International Limited Needle device and method thereof
US6499617B1 (en) 2000-07-17 2002-12-31 Brocco Diagnostics, Inc. Rotary seal stopper
JP2002035140A (ja) 2000-07-21 2002-02-05 Terumo Corp コネクタ
ES2605353T3 (es) 2000-08-02 2017-03-14 Becton, Dickinson And Company Sistema de aguja de pluma y pantalla protectora de seguridad
JP2004508897A (ja) 2000-09-21 2004-03-25 エラン・ファルマ・インターナショナル・リミテッド 再形成および注入システム
FR2815328B1 (fr) 2000-10-17 2002-12-20 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
JP2002191695A (ja) 2000-10-20 2002-07-09 Mitsubishi Pencil Co Ltd 針先カバー部材、針先カバー部材付き注射針の組立方法、針ガード部材付き注射針および針ガード部材付き注射器
US6769430B1 (en) 2000-10-31 2004-08-03 Kimberly-Clark Worldwide, Inc. Heat and moisture exchanger adaptor for closed suction catheter assembly and system containing the same
JP2002177392A (ja) 2000-11-08 2002-06-25 West Pharmaceutical Services Inc 注射器安全装置
US6666852B2 (en) 2000-12-04 2003-12-23 Bracco Diagnostics, Inc. Axially activated vial access adapter
FR2817566B1 (fr) 2000-12-04 2003-02-07 Freyssinet Int Stup Toron individuellement protege, son utilisation dans la construction, et procede de fabrication
US20020087118A1 (en) 2000-12-29 2002-07-04 Duoject Medical Systems Inc. Pharmaceutical delivery system
US6558365B2 (en) * 2001-01-03 2003-05-06 Medimop Medical Projects, Ltd. Fluid transfer device
USD468015S1 (en) 2001-01-22 2002-12-31 Astra Tech Ab Combined connector with valve and non-return valve for medical equipment
US6474375B2 (en) 2001-02-02 2002-11-05 Baxter International Inc. Reconstitution device and method of use
WO2002066100A2 (en) 2001-02-20 2002-08-29 Medrad, Inc. Syringes, connectors, and syringe and connector systems for use in fluid delivery systems
US6503244B2 (en) 2001-03-07 2003-01-07 Micro Therapeutics, Inc. High pressure injection system
US6656433B2 (en) 2001-03-07 2003-12-02 Churchill Medical Systems, Inc. Vial access device for use with various size drug vials
US6685692B2 (en) 2001-03-08 2004-02-03 Abbott Laboratories Drug delivery system
US20020138045A1 (en) 2001-03-20 2002-09-26 Moen Michael E. Quick connect fitting
CA2440873C (en) 2001-03-27 2010-12-07 Eli Lilly And Company Kit including side firing syringe needle for preparing a drug in an injection pen cartridge
US6581593B1 (en) 2001-04-03 2003-06-24 Darren A. Rubin Universal oxygen connector system
WO2002089900A1 (en) 2001-05-07 2002-11-14 Nexell Therapeutics Inc. Fluid connector devices and methods of use
JP2002355318A (ja) 2001-06-01 2002-12-10 Terumo Corp 弁体付コネクター
EP1264609B1 (en) 2001-06-06 2006-01-18 Graziano Azzolini High-sterility and high-capacity connector for lines for outflow from bottles
USD457954S1 (en) 2001-06-19 2002-05-28 Becton, Dickinson And Company Syringe tip cap
JP2003033441A (ja) 2001-07-23 2003-02-04 Terumo Corp 三方活栓
US6453949B1 (en) 2001-08-08 2002-09-24 Sam Chau Plug for medical bayonet connectors and drug infusion ports
US6745998B2 (en) 2001-08-10 2004-06-08 Alaris Medical Systems, Inc. Valved male luer
USD476731S1 (en) 2001-08-27 2003-07-01 Kimberly-Clark Worldwide, Inc. Bendable connector
DE10142450C1 (de) 2001-08-31 2003-06-18 Aventis Behring Gmbh Vorrichtung zum Zusammenführen von Komponenten unter sterilen Bedingungen
FR2829691B1 (fr) 2001-09-17 2004-07-09 Sedat Dispositif de transfert bidirectionnel d'un liquide entre un flacon et une carpule
US7354422B2 (en) 2001-09-26 2008-04-08 B. Braun Melsungen Ag Spring launched needle safety clip
JP4817564B2 (ja) 2001-09-28 2011-11-16 株式会社細川洋行 ニードルケース及び輸液容器
DE10149251B4 (de) 2001-10-05 2007-04-19 Sartorius Ag Vorrichtung zur genetischen Immunisierung durch Einbringen von Wirkstoffen in ein Gewebe und Verfahren zur Herstellung einer Injektionslösung
US20030069550A1 (en) 2001-10-06 2003-04-10 Sharp M. Keith Hypodermic needle
US6715520B2 (en) 2001-10-11 2004-04-06 Carmel Pharma Ab Method and assembly for fluid transfer
US20030073971A1 (en) 2001-10-17 2003-04-17 Saker Gordon Mark Universal connector and method for securing flexible tube assemblies
EP2092950A3 (en) 2001-11-14 2009-09-02 JMS Co., Ltd. Three-way stopcock, and liquid transfusion tubing set or blood transfusion tubing set using the three-way stopcock
US6802828B2 (en) 2001-11-23 2004-10-12 Duoject Medical Systems, Inc. System for filling and assembling pharmaceutical delivery devices
US6802490B2 (en) 2001-11-29 2004-10-12 Alaris Medical Systems, Inc. Needle free medical connector with expanded valve mechanism and method of fluid flow control
ES2257597T3 (es) 2001-11-30 2006-08-01 Novo Nordisk A/S Ensamblaje de aguja de seguridad.
JP4451661B2 (ja) 2001-12-13 2010-04-14 ベクトン・ディキンソン・アンド・カンパニー 注射針閉鎖システム除去装置
ES2262733T3 (es) 2001-12-17 2006-12-01 Bristol-Myers Squibb Company Dispositivo de transferencia y sistema que comprende un conjunto de tapa, un recipiente y el dispositivo de transferencia.
US6651956B2 (en) 2002-01-31 2003-11-25 Halkey-Roberts Corporation Slit-type swabable valve
US6875205B2 (en) 2002-02-08 2005-04-05 Alaris Medical Systems, Inc. Vial adapter having a needle-free valve for use with vial closures of different sizes
FR2836129B1 (fr) 2002-02-20 2004-04-02 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
AU2003201335B2 (en) 2002-03-20 2009-07-23 Becton, Dickinson And Company Shieldable needle assembly with biased safety shield
US8562583B2 (en) 2002-03-26 2013-10-22 Carmel Pharma Ab Method and assembly for fluid transfer and drug containment in an infusion system
US9440046B2 (en) 2002-04-04 2016-09-13 Angiodynamics, Inc. Venous insufficiency treatment method
US7744581B2 (en) 2002-04-08 2010-06-29 Carmel Pharma Ab Device and method for mixing medical fluids
US7867215B2 (en) 2002-04-17 2011-01-11 Carmel Pharma Ab Method and device for fluid transfer in an infusion system
US6740277B2 (en) 2002-04-24 2004-05-25 Becton Dickinson And Company Process of making a catheter
USD472316S1 (en) 2002-04-30 2003-03-25 Sterling Medivations, Inc. Pen needle catheter connector
USD472630S1 (en) 2002-04-30 2003-04-01 Sterling Medivations, Inc. Pen needle catheter connector
US6914212B2 (en) 2002-05-01 2005-07-05 Becton Dickinson And Company Method of making a needle and a needle
USD476733S1 (en) 2002-05-09 2003-07-01 Becton, Dickinson And Company Medical needle assembly
CA2486005C (en) 2002-05-16 2008-08-26 Scott Laboratories, Inc. Drug container entry mechanisms and method
US20030236543A1 (en) 2002-06-25 2003-12-25 Brenneman Allen J. Polygonal cross section lancet needle
JP4427965B2 (ja) 2002-07-02 2010-03-10 ニプロ株式会社 連通手段付き薬液容器
SE523001C2 (sv) 2002-07-09 2004-03-23 Carmel Pharma Ab En kopplingsdel, en koppling, en infusionspåse, en infusionsanordning och ett förfarande för överföring av medicinska substanser
US20040010207A1 (en) 2002-07-15 2004-01-15 Flaherty J. Christopher Self-contained, automatic transcutaneous physiologic sensing system
JP4209642B2 (ja) 2002-07-26 2009-01-14 川澄化学工業株式会社 針カバー及びキャップ付針カバー並びに針カバー付翼付針
US7326188B1 (en) 2002-08-02 2008-02-05 Elcam Medical Anesthesia manifold and induction valve
US7083600B2 (en) 2002-08-08 2006-08-01 Advanced Medical Sharps, Inc. Safety needle and shield
JP2004097253A (ja) 2002-09-04 2004-04-02 Nipro Corp 液体移注具
USD482121S1 (en) 2002-09-17 2003-11-11 Becton Dickinson And Company Needleless luer access port
USD482447S1 (en) 2002-09-17 2003-11-18 Becton Dickinson And Company Needleless luer access port
US6979318B1 (en) 2002-10-07 2005-12-27 Lemaitre Vascular, Inc. Catheter introducer
US20040073189A1 (en) 2002-10-09 2004-04-15 Phil Wyatt Vial access transfer set
US7544191B2 (en) 2002-10-22 2009-06-09 Baxter International Inc. Formed, filled, sealed solution container, port and method for establishing flow between the container and an administration set
USD483869S1 (en) 2002-10-29 2003-12-16 Pre Holding, Inc. Tubing connector
EP1558194A1 (en) 2002-11-08 2005-08-03 Duoject Medical Systems Inc Pharmaceutical delivery systems and methods for using same
US8100879B2 (en) 2002-11-18 2012-01-24 Nestec S.A. Connector device for enteral administration set
CH696186A5 (de) 2002-11-25 2007-02-15 Tecpharma Licensing Ag Vorrichtung zur Sicherung von Injektionsnadeln.
USD506256S1 (en) 2002-11-26 2005-06-14 Nipro Corporation Adapter for transfer of medical solution
US7086431B2 (en) 2002-12-09 2006-08-08 D'antonio Consultants International, Inc. Injection cartridge filling apparatus
USD483487S1 (en) 2002-12-19 2003-12-09 Becton Dickinson And Company Stopcock device
JP4341239B2 (ja) 2002-12-19 2009-10-07 ニプロ株式会社 液体移注具
US7125396B2 (en) 2002-12-30 2006-10-24 Cardinal Health 303, Inc. Safety catheter system and method
US7140592B2 (en) 2002-12-31 2006-11-28 Cardinal Health 303, Inc. Self-sealing male Luer connector with biased valve plug
US20040143226A1 (en) 2003-01-16 2004-07-22 Becton, Dickinson And Company Blood collection set with venting mechanism
US20040143218A1 (en) 2003-01-21 2004-07-22 Animas Corporation Needle having optimum grind for reduced insertion force
US7678333B2 (en) 2003-01-22 2010-03-16 Duoject Medical Systems Inc. Fluid transfer assembly for pharmaceutical delivery system and method for using same
US7229419B2 (en) 2003-02-11 2007-06-12 Promex/U.S. Biosy Llc Single-handed biopsy system
US20040162540A1 (en) 2003-02-13 2004-08-19 Becton, Dickinson And Company Transfer device
DK1454609T3 (da) 2003-03-05 2013-02-11 Csl Behring Gmbh Overføringsindretning
EP1454650B1 (de) 2003-03-06 2007-10-10 CSL Behring GmbH Transfervorrichtung, insbesondere für medizinische Fluids
US20040181192A1 (en) 2003-03-11 2004-09-16 Cuppy Michael John Vascular access device and method of using same
US7470262B2 (en) 2003-03-17 2008-12-30 Nipro Corporation Medical valve
US7470265B2 (en) 2003-03-20 2008-12-30 Nxstage Medical, Inc. Dual access spike for infusate bags
US7024968B2 (en) 2003-03-26 2006-04-11 Boston Scientific Scimed, Inc. Luer lock wrench
US7001369B2 (en) 2003-03-27 2006-02-21 Scimed Life Systems, Inc. Medical device
EP1631496B1 (en) 2003-04-28 2014-02-26 Medical Instill Technologies, Inc. Container with valve assembly for filling and dispensing substances, and apparatus and method for filling
US7040598B2 (en) 2003-05-14 2006-05-09 Cardinal Health 303, Inc. Self-sealing male connector
USD495416S1 (en) 2003-05-30 2004-08-31 Alaris Medical Systems, Inc. Vial access device
US20040249235A1 (en) 2003-06-03 2004-12-09 Connell Edward G. Hazardous material handling system and method
WO2004112866A2 (en) 2003-06-17 2004-12-29 Filtertek Inc. Fluid handling device and method of making same
FR2856660A1 (fr) 2003-06-30 2004-12-31 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
ITMO20030204A1 (it) 2003-07-14 2005-01-15 Gambro Lundia Ab Sacca per dialisi, set per dialisi comprendente detta
JP3883527B2 (ja) 2003-07-17 2007-02-21 ニプロ株式会社 トランスファーニードル
US7488297B2 (en) 2003-07-30 2009-02-10 Patrice Flaherty Blood collecting devices
US6960164B2 (en) 2003-08-01 2005-11-01 Neosurg Technologies, Inc. Obturator tip for a trocar
CN1863566B (zh) 2003-08-12 2010-09-01 贝克顿·迪金森公司 片状输液装置
EP2609947B1 (en) 2003-08-12 2020-04-15 Becton, Dickinson and Company Patch-like infusion device
FR2858931B1 (fr) 2003-08-21 2007-04-13 Becton Dickinson France Dispositif d'administration orale d'un medicament
US7097637B2 (en) 2003-08-27 2006-08-29 C. R. Bard, Inc. Safety needle with positive flush
US20050082828A1 (en) 2003-09-12 2005-04-21 Wicks Jeffrey C. Releasable connection assembly for joining tubing sections
WO2005041846A2 (en) 2003-10-30 2005-05-12 Teva Medical Ltd. Safety drug handling device
FR2863161B1 (fr) 2003-12-05 2006-09-01 Map France Capuchon pour conditionnement de securite pour flacon a usage medical
WO2005058744A2 (en) 2003-12-11 2005-06-30 Gregory Lambrecht Wine extraction and preservation device and method
US20080009822A1 (en) 2003-12-18 2008-01-10 Halkey-Roberts Corporation Needleless access vial
MXPA06006962A (es) 2003-12-18 2007-01-30 Halkey Roberts Corp Frasco de acceso sin agua.
US8454573B2 (en) 2008-05-06 2013-06-04 Philip Wyatt Medicament administration apparatus
US20050137523A1 (en) 2003-12-22 2005-06-23 Wyatt Philip W. Medicament administration apparatus
US6997916B2 (en) 2004-01-02 2006-02-14 Smiths Medical Asd, Inc. Fluid transfer holder assembly and a method of fluid transfer
US7530546B2 (en) 2004-01-13 2009-05-12 Rymed Technologies, Inc. Swabbable needle-free injection port valve system with zero fluid displacement
US6994315B2 (en) 2004-01-13 2006-02-07 Rymed Technologies, Inc. Swabbable needle-free injection port valve system with neutral fluid displacement
US20050159706A1 (en) 2004-01-20 2005-07-21 Becton, Dickinson And Company Medical syringe with safety shield system
DE102004005435B3 (de) 2004-02-04 2005-09-15 Haindl, Hans, Dr. Medizinisches Transfergerät
IL160891A0 (en) 2004-03-16 2004-08-31 Auto-mix needle
US20050209554A1 (en) 2004-03-19 2005-09-22 Sergio Landau Needle-free single-use cartridge and injection system
ATE540721T1 (de) 2004-03-26 2012-01-15 Cook Medical Technologies Llc Verfahren und gerät für eine verbesserte luer- verbindung
IL161660A0 (en) 2004-04-29 2004-09-27 Medimop Medical Projects Ltd Liquid drug delivery device
DE102004021670A1 (de) 2004-05-03 2005-12-01 Saint-Gobain Calmar Gmbh Manuell betätigbarer Spender mit Schutzkappe
FR2869795B1 (fr) 2004-05-07 2006-08-04 Sedat Sa Dispositif de transfert bidirectionnel
US20050261637A1 (en) 2004-05-21 2005-11-24 Halkey-Roberts Corporation T-port with swabbable valve
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
DE102004036051A1 (de) 2004-07-24 2006-02-16 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Spritze
US7615041B2 (en) 2004-07-29 2009-11-10 Boston Scientific Scimed, Inc. Vial adaptor
DE202004012714U1 (de) 2004-08-12 2004-11-04 Smiths Medical Deutschland Gmbh Luer-Lock-Verbinder für medizinische Geräte
DE102004039408A1 (de) 2004-08-13 2006-03-02 Disetronic Licensing Ag Insertionskopf für medizinische oder pharmazeutische Anwendungen
JP2006061421A (ja) 2004-08-26 2006-03-09 Bio Media Co Ltd 薬剤収容ユニット
CA2578989C (en) 2004-09-03 2014-02-25 Elcam Medical Agricultural Cooperative Association Ltd. Stopcock
US20060161192A1 (en) 2004-09-03 2006-07-20 Young Christopher S Wound needle with composite cutting edge
EP2077512A1 (en) 2004-10-04 2009-07-08 Clearpace Software Limited Method and system for implementing an enhanced database
US7731678B2 (en) 2004-10-13 2010-06-08 Hyprotek, Inc. Syringe devices and methods for mixing and administering medication
JP4821947B2 (ja) 2004-10-19 2011-11-24 朝日インテック株式会社 薬液注入装置
US7771383B2 (en) 2004-10-22 2010-08-10 Medegen, Inc. Fluid control device with valve and methods of use
US20060089594A1 (en) 2004-10-26 2006-04-27 Sergio Landau Needle-free injection device
US7192423B2 (en) 2004-11-17 2007-03-20 Cindy Wong Dispensing spike assembly with removable indicia bands
US8826988B2 (en) 2004-11-23 2014-09-09 Weatherford/Lamb, Inc. Latch position indicator system and method
US7241285B1 (en) 2004-12-06 2007-07-10 Medical Ventures, Inc. Medical site connection
FR2878737B1 (fr) 2004-12-07 2007-03-16 Maptech Soc Par Actions Simpli Dispositif de securite pour flacon a usage medical
US7645274B2 (en) 2004-12-10 2010-01-12 Cardinal Health 303, Inc. Self-sealing male luer connector with multiple seats
US7523967B2 (en) 2004-12-13 2009-04-28 Alcon, Inc. Tubing fitting
US20060135948A1 (en) 2004-12-16 2006-06-22 Medtronic Vascular, Inc., A Delaware Corporation Multi-exchange catheter guide member with improved seal
US7935070B2 (en) 2005-01-28 2011-05-03 Fresenius Medical Care North America Systems and methods for dextrose containing peritoneal dialysis (PD) solutions with neutral pH and reduced glucose degradation product
US7704229B2 (en) 2005-02-03 2010-04-27 Medtronic Minimed, Inc. Insertion device
US7651482B2 (en) 2005-02-04 2010-01-26 Boston Scientific Scimed, Inc. Non-coring needles and methods of manufacturing same
US7862537B2 (en) 2005-02-14 2011-01-04 Medimop Medical Projects Ltd. Medical device for in situ liquid drug reconstitution in medicinal vessels
US20090076360A1 (en) 2007-09-13 2009-03-19 Dexcom, Inc. Transcutaneous analyte sensor
US20070060904A1 (en) 2005-03-14 2007-03-15 Becton, Dickinson And Company Filling system and method for syringes with short needles
US7666172B2 (en) 2005-03-15 2010-02-23 Plaridel Cerna Atil Medical needle having a closed tip
US20060253084A1 (en) 2005-05-03 2006-11-09 Greg Nordgren Outdwelling slit valves and assemblies for medical liquid flow through a cannula and related methods
WO2006124756A2 (en) 2005-05-13 2006-11-23 Bob Rogers Medical substance transfer system
CA111438S (fr) 2005-05-23 2006-12-22 Rexam Dispensing Sys Pulvérisateur nasal
US7803139B2 (en) 2005-07-06 2010-09-28 Icu Medical, Inc. Medical connector with closeable male luer
JP2007024928A (ja) 2005-07-12 2007-02-01 Nidec Sankyo Corp 光ビーム出射装置および画像形成装置
EP1909735A1 (en) 2005-08-01 2008-04-16 Medimop Medical Projects Ltd. Liquid drug delivery system
EP1919432B1 (en) 2005-08-11 2011-10-19 Medimop Medical Projects Ltd. Liquid drug transfer devices for failsafe correct snap fitting onto medicinal vials
DE502005011091D1 (de) 2005-09-15 2011-04-21 Roche Diagnostics Gmbh System aus Insertionskopf und Inserter
DE502005009907D1 (de) 2005-09-15 2010-08-26 Roche Diagnostics Gmbh Insertionskopf mit Griff
US8409142B2 (en) 2005-09-26 2013-04-02 Asante Solutions, Inc. Operating an infusion pump system
US20090043253A1 (en) 2005-10-11 2009-02-12 Blake Podaima Smart medical compliance method and system
US7882863B2 (en) 2005-10-19 2011-02-08 Cd Solutions, Llc Apparatus and method for mixing and transferring medications
US7611502B2 (en) 2005-10-20 2009-11-03 Covidien Ag Connector for enteral fluid delivery set
EP1957028B1 (en) 2005-10-30 2017-06-07 Medimop Medical Projects Ltd. Needleless additive control valve
US7743799B2 (en) 2005-11-07 2010-06-29 Industrie Borta S.p.A. Vented safe handling vial adapter
US7935104B2 (en) 2005-11-07 2011-05-03 Medingo, Ltd. Systems and methods for sustained medical infusion and devices related thereto
DE102005055326A1 (de) 2005-11-11 2007-05-16 Storz Karl Gmbh & Co Kg Anschluss für ein medizinisches Saug- oder Spülinstrument
GB0523638D0 (en) 2005-11-21 2005-12-28 Cambridge Biostability Ltd Pharmaceutical device for the administration of substances to patients
JP2007143813A (ja) 2005-11-28 2007-06-14 Nippon Sherwood Medical Industries Ltd 医療用活栓
US20070191767A1 (en) 2005-12-16 2007-08-16 Medtronic Vascular, Inc. Bifurcated Catheter Joints
US7981101B2 (en) 2005-12-30 2011-07-19 Carefusion 303, Inc. Medical vial adapter with reduced diameter cannula and enlarged vent lumen
DE502006005333D1 (de) 2006-02-16 2009-12-24 Roche Diagnostics Gmbh System und Vorrichtung zum Entnehmen von Pharmazeutika
JP2007222472A (ja) 2006-02-24 2007-09-06 Nipro Corp 薬剤微量投与具セット
EP1911432A1 (en) 2006-10-10 2008-04-16 Novo Nordisk A/S A mixing unit
WO2007101772A1 (en) 2006-03-07 2007-09-13 Novo Nordisk A/S A drug mixing device
EP1991110B1 (en) 2006-03-09 2018-11-07 DexCom, Inc. Systems and methods for processing analyte sensor data
IL174352A0 (en) 2006-03-16 2006-08-20 Medimop Medical Projects Ltd Medical devices for use with carpules
JP4769103B2 (ja) 2006-03-17 2011-09-07 日本シャーウッド株式会社 コネクタ
FR2898812B1 (fr) 2006-03-24 2008-06-13 Technoflex Sa Connecteur luer, connecteur medical et set de transfert comportant un tel connecteur
AU2007242198B2 (en) 2006-03-29 2012-02-16 Terumo Kabushiki Kaisha Protector
JP4775638B2 (ja) 2006-03-31 2011-09-21 株式会社ジェイ・エム・エス 連通部材、およびそれを用いた医療用容器、並びに輸液調剤用具セット
US7547300B2 (en) 2006-04-12 2009-06-16 Icu Medical, Inc. Vial adaptor for regulating pressure
WO2007118372A1 (fr) 2006-04-18 2007-10-25 Zhongshan Botai Pharmaceutic Instruments Co., Ltd. Seringue stérilisée servant au mélange de médicaments
JP4820703B2 (ja) 2006-04-28 2011-11-24 日本シャーウッド株式会社 液体混注具
US7731735B2 (en) 2006-04-28 2010-06-08 Warsaw Orthopedic, Inc. Open axle surgical implant
US9295790B2 (en) 2006-05-05 2016-03-29 Retractable Technologies, Inc. Syringe with recessed nose and protective guard for use with frontal attachments
JP4871019B2 (ja) 2006-05-15 2012-02-08 日本コヴィディエン株式会社 液体混注具
JP4897879B2 (ja) 2006-05-25 2012-03-14 バイエル・ヘルスケア・エルエルシー 再構成デバイス
US20090318946A1 (en) 2006-06-02 2009-12-24 Yuji Tamesada Pricking Needle and Lancet Having The Same
CN101466344B (zh) 2006-06-19 2012-06-06 尼普洛株式会社 药液调制用套件
JP2008005974A (ja) 2006-06-28 2008-01-17 Nippon Sherwood Medical Industries Ltd ルアー固定フィッティング接続構造
DK2043585T3 (da) 2006-07-21 2010-08-16 Polimoon Medical Packaging As Forbindelsesindretning og fremgangsmåde til steril blanding
USD561348S1 (en) 2006-08-17 2008-02-05 Medimop Medical Projects Ltd. Vial adapter
US7670326B2 (en) 2006-09-25 2010-03-02 Teva Medical Ltd.. Syringe adapter element in drug mixing system
DE102006049528A1 (de) 2006-09-28 2008-04-03 Robert Bosch Gmbh Vorrichtung und Verfahren zur Montage eines Nadelschutzes auf einen Spritzenkörper
USD580558S1 (en) 2006-09-29 2008-11-11 Fujifilm Corporation Cap of cartridge for component extraction
US8167863B2 (en) 2006-10-16 2012-05-01 Carefusion 303, Inc. Vented vial adapter with filter for aerosol retention
DE602007014252D1 (de) 2006-10-25 2011-06-09 Icu Medical Inc Medizinischer verbinder
US20100076397A1 (en) 2006-11-30 2010-03-25 Jay Reed Dual-lumen needle with an elongate notch opening
WO2008067506A1 (en) 2006-11-30 2008-06-05 Medi-Physics, Inc. Dual-lumen needle
US7758082B2 (en) 2006-12-05 2010-07-20 Nxstage Medical, Inc. Fluid line connector safety device
US20080135051A1 (en) 2006-12-07 2008-06-12 George Lee Air Line Adapter Structure Of Suction Apparatus
US8002756B2 (en) 2006-12-08 2011-08-23 Becton, Dickinson And Company Method and apparatus for delivering a therapeutic substance through an injection port
US8057431B2 (en) 2006-12-21 2011-11-15 B. Braun Melsungen Ag Hinged cap for needle device
CN101610803A (zh) 2006-12-21 2009-12-23 Ssb技术有限公司 针尖
IL180565A0 (en) 2007-01-04 2007-06-03 Ilan Brand An improved stopcock for administering medicaments into the patient's body
US8523830B2 (en) 2007-01-16 2013-09-03 Catheter Connections Disinfecting caps for medical female luer connectors
GB2446778A (en) 2007-02-01 2008-08-27 Pa Knowledge Ltd Syringe adaptor
US8038654B2 (en) 2007-02-26 2011-10-18 Becton, Dickinson And Company Syringe having a hinged needle shield
US7883499B2 (en) 2007-03-09 2011-02-08 Icu Medical, Inc. Vial adaptors and vials for regulating pressure
DK1970084T3 (da) 2007-03-14 2010-11-22 Hoffmann La Roche Indføringsapparat til en indføringshoved, især til et infusionssæt
GB0705782D0 (en) 2007-03-26 2007-05-02 Novartis Ag Vial assemblies
IL182605A0 (en) 2007-04-17 2007-07-24 Medimop Medical Projects Ltd Fluid control device with manually depressed actuator
BRPI0810582A2 (pt) 2007-04-23 2015-10-27 Program For Appropriate Technology In Health métodos e dispositivos para injeção intradérmica
EP2139442B1 (en) 2007-04-23 2014-04-02 Plastmed Ltd. Method and apparatus for contamination-free transfer of a hazardous drug
US7963954B2 (en) 2007-04-30 2011-06-21 Medtronic Minimed, Inc. Automated filling systems and methods
US8323250B2 (en) 2007-04-30 2012-12-04 Medtronic Minimed, Inc. Adhesive patch systems and methods
IL182922A0 (en) 2007-05-02 2007-09-20 Medimop Medical Projects Ltd Automatic liquid drug reconstitution apparatus
US20080306439A1 (en) 2007-06-08 2008-12-11 Nelson M Bud Devices for mixing and applying a fluid composition
USD588693S1 (en) 2007-06-12 2009-03-17 Nordson Corporation Liquid dispensing syringe
US8657803B2 (en) 2007-06-13 2014-02-25 Carmel Pharma Ab Device for providing fluid to a receptacle
EP2170437A2 (en) 2007-07-20 2010-04-07 Amylin Pharmaceuticals, Inc. Pen injection device and method of using same
US8216207B2 (en) 2007-08-01 2012-07-10 Hospira, Inc. Medicament admixing system
GB0716159D0 (en) 2007-08-17 2007-09-26 Precisense As Injection apparatus
WO2009026443A2 (en) 2007-08-21 2009-02-26 Gilero, Llc Vial access and injection system
US9968742B2 (en) 2007-08-29 2018-05-15 Medtronic Minimed, Inc. Combined sensor and infusion set using separated sites
EP2190401B1 (en) 2007-08-30 2015-05-20 Carmel Pharma AB Device, sealing member and fluid container
US8287513B2 (en) 2007-09-11 2012-10-16 Carmel Pharma Ab Piercing member protection device
US20110276007A1 (en) 2007-09-18 2011-11-10 Igor Denenburg Safety needle device
EP2190518B1 (en) 2007-09-18 2016-01-27 Medimop Medical Projects Ltd. Medicament mixing and injection apparatus
IL186290A0 (en) 2007-09-25 2008-01-20 Medimop Medical Projects Ltd Liquid drug delivery devices for use with syringe having widened distal tip
DE102007046951B3 (de) 2007-10-01 2009-02-26 B. Braun Melsungen Ag Vorrichtung zum Einführen eines Medikaments in einen Infusionsbehälter
USD616090S1 (en) 2007-10-29 2010-05-18 Daikyo Seiko, Ltd. Sealing device for medicine container or medical apparatus
WO2009060419A2 (en) 2007-11-08 2009-05-14 Elcam Medical A.C.A..L. Ltd Vial adaptor and manufacturing method therfor
DE102007061346A1 (de) 2007-12-17 2009-06-18 Bayer Schering Pharma Aktiengesellschaft Spike mit zwei Dornen
US9039673B2 (en) 2008-01-09 2015-05-26 Novartis Ag Unitary withdrawal spike unit suitable for factory fitting
US8287496B2 (en) 2008-01-17 2012-10-16 Custom Medical Applications, Inc. Flow elements for use with flexible spinal needles, needle assemblies and methods therefor
IL188975A0 (en) 2008-01-23 2008-11-03 Medimop Medical Projects Ltd Fluid control device with stopper
FR2927533B1 (fr) 2008-02-18 2011-02-11 P2A Medical Capuchon de transfert securise
DK2254542T3 (da) 2008-02-18 2012-10-15 Icu Medical Inc Flaskeadapter
DE102008002800A1 (de) 2008-03-10 2009-09-24 Süddeutsche Feinmechanik GmbH Mischvorrichtung
WO2009146088A1 (en) 2008-04-01 2009-12-03 Yukon Medical, Llc Dual container fluid transfer device
US20090267011A1 (en) 2008-04-23 2009-10-29 Jason Hatton Dispensing valve assembly
FR2931363B1 (fr) 2008-05-23 2010-06-25 Vygon Connecteur pour circuit de liquide, notamment a usage medical et utilisation d'un tel connecteur
US8075550B2 (en) 2008-07-01 2011-12-13 Carmel Pharma Ab Piercing member protection device
US7967785B2 (en) 2008-07-14 2011-06-28 Nipro Healthcare Systems, Llc Insulin reservoir detection via magnetic switching
USD595862S1 (en) 2008-07-18 2009-07-07 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595420S1 (en) 2008-07-18 2009-06-30 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595863S1 (en) 2008-07-18 2009-07-07 Hitachi High-Technologies Corporation Adapter for a sample rack
USD595421S1 (en) 2008-07-18 2009-06-30 Hitachi High-Technologies Corporation Adapter for a sample rack
GB0814747D0 (en) 2008-08-13 2008-09-17 Owen Mumford Ltd Autoinjection devices
WO2010021749A2 (en) 2008-08-22 2010-02-25 Circle Biologics, Llc Fluid management devices and methods
US8480645B1 (en) 2008-08-22 2013-07-09 Sambhu N. Choudhury Multi-dose device for insertion into a vial and method of using the same
JP5854836B2 (ja) 2008-08-30 2016-02-09 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング カートリッジ及びそのための針システム
JP5266990B2 (ja) 2008-09-10 2013-08-21 ニプロ株式会社 薬剤調製器具
US8523837B2 (en) 2008-10-14 2013-09-03 Mead Johnson Nutrition Company Nutritive substance delivery container
US7762524B2 (en) 2008-10-20 2010-07-27 Baxter International Inc. Barrier assembly for use with needleless connector
EP2355770A1 (en) 2008-11-12 2011-08-17 British Columbia Cancer Agency Branch Vial handling and injection safety systems and connectors
EP2351548B1 (en) 2008-11-21 2016-01-27 Terumo Kabushiki Kaisha Connector
CN102196798B (zh) 2008-11-25 2014-04-09 株式会社Jms 连接器
JP5557040B2 (ja) 2008-11-25 2014-07-23 株式会社ジェイ・エム・エス コネクタ
US9370621B2 (en) 2008-12-16 2016-06-21 Medtronic Minimed, Inc. Needle insertion systems and methods
US20100160889A1 (en) 2008-12-22 2010-06-24 Baxter International Inc. Vial access spike assembly
EP2201968A1 (de) 2008-12-24 2010-06-30 Roche Diagnostics GmbH Insertionssystem und Insertionsvorrichtung
US8152779B2 (en) 2008-12-30 2012-04-10 Medimop Medical Projects Ltd. Needle assembly for drug pump
US8512309B2 (en) 2009-01-15 2013-08-20 Teva Medical Ltd. Vial adapter element
US8221352B2 (en) 2009-01-29 2012-07-17 Michael Merchant Disposable safety needle system and safety enclosure means
EP2393533B1 (en) 2009-02-05 2015-03-25 Sanofi-Aventis Deutschland GmbH Medicament delivery devices
US8123736B2 (en) 2009-02-10 2012-02-28 Kraushaar Timothy Y Cap adapters for medicament vial and associated methods
US8012132B2 (en) 2009-02-24 2011-09-06 Becton, Dickinson And Company Luer-snap connection and luer-snap syringe
USD608900S1 (en) 2009-03-06 2010-01-26 Csp Technologies, Inc. Identification component for a vial
US8864725B2 (en) 2009-03-17 2014-10-21 Baxter Corporation Englewood Hazardous drug handling system, apparatus and method
USD641080S1 (en) 2009-03-31 2011-07-05 Medimop Medical Projects Ltd. Medical device having syringe port with locking mechanism
USD634007S1 (en) 2009-03-31 2011-03-08 Medimop Medical Projects Ltd. Needleless additive control valve
US8182452B2 (en) 2009-04-06 2012-05-22 Carefusion 303, Inc. Closed male luer device for use with needleless access devices
AU2010236426B2 (en) * 2009-04-14 2013-08-29 Yukon Medical, Llc Fluid transfer device
US7963939B2 (en) 2009-04-24 2011-06-21 Thomas Chun Syringe having extended blending path
US8308741B2 (en) 2009-04-28 2012-11-13 The Invention Science Fund I, Llc Systems and methods for automatically inserting a needle into a living subject
DE202009011019U1 (de) 2009-07-01 2010-12-02 Süddeutsche Feinmechanik GmbH Anordnung zum Entnehmen eines Mediums aus einem Fläschchen
BR122012017389B8 (pt) 2009-07-01 2021-06-22 Fresenius Medical Care Holdings Inc dispositivo para administração de fármacos
USD616984S1 (en) 2009-07-02 2010-06-01 Medimop Medical Projects Ltd. Vial adapter having side windows
IL199767A0 (en) 2009-07-09 2010-04-15 Medimop Medical Projects Ltd Medical device for use with cartridge and vial
JP5333850B2 (ja) 2009-07-15 2013-11-06 ニプロ株式会社 連結器具
USD655071S1 (en) 2009-07-17 2012-03-06 Julia Graciela Davila Mariachi suit
USD627216S1 (en) 2009-07-21 2010-11-16 The United States Of America As Represented By The Director, National Security Agency Tamper cup seal
IL200547A (en) 2009-08-23 2014-06-30 Eli Shemesh A system for mixing drugs in many containers
US9149624B2 (en) 2009-09-02 2015-10-06 Carefusion 303, Inc. Disinfecting male luer connector caps
USD630732S1 (en) 2009-09-29 2011-01-11 Medimop Medical Projects Ltd. Vial adapter with female connector
IL201323A0 (en) 2009-10-01 2010-05-31 Medimop Medical Projects Ltd Fluid transfer device for assembling a vial with pre-attached female connector
CA2778105C (en) 2009-10-23 2019-04-02 Amgen Inc. Vial adapter and system
IL202070A0 (en) 2009-11-12 2010-06-16 Medimop Medical Projects Ltd Inline liquid drug medical device
IL202069A0 (en) 2009-11-12 2010-06-16 Medimop Medical Projects Ltd Fluid transfer device with sealing arrangement
USD637713S1 (en) 2009-11-20 2011-05-10 Carmel Pharma Ab Medical device adaptor
US8480646B2 (en) 2009-11-20 2013-07-09 Carmel Pharma Ab Medical device connector
JP5379314B2 (ja) 2009-12-23 2013-12-25 メディモップ・メディカル・プロジェクツ・リミテッド 液剤用量を復元し投与するための、医療用装置、および、この医療用装置とともに使用するための流れ制御デバイスを含む一回使い切りキット
US8998840B2 (en) 2009-12-30 2015-04-07 Medtronic Minimed, Inc. Connection and alignment systems and methods
CN102869397B (zh) 2010-01-15 2015-10-14 拜耳医药保健有限公司 装置
US20120310203A1 (en) 2010-01-19 2012-12-06 Cambridge Enterprise Limited Apparatus and method
US8348898B2 (en) 2010-01-19 2013-01-08 Medimop Medical Projects Ltd. Automatic needle for drug pump
EP2361599A1 (de) 2010-02-22 2011-08-31 Fresenius Kabi Deutschland GmbH Vorrichtung zum Zuführen oder Entnehmen einer Flüssigkeit in ein oder aus einem Behältnis
WO2011111469A1 (ja) 2010-03-10 2011-09-15 テルモ株式会社 注射針組立体及び薬剤注射装置
USD644104S1 (en) 2010-04-15 2011-08-30 Sumitomo Rubber Industries, Ltd. Rubber stopper for vial
US8702674B2 (en) 2010-04-27 2014-04-22 Crisi Medical Systems, Inc. Medication and identification information transfer apparatus
MX2012013426A (es) 2010-05-20 2013-02-12 Becton Dickinson Co Dispositivo de administracion de farmacos.
AU2011265005B2 (en) 2010-06-07 2015-04-09 Amgen Inc. Drug delivery device
USD655017S1 (en) 2010-06-17 2012-02-28 Yukon Medical, Llc Shroud
US9526841B2 (en) 2010-06-30 2016-12-27 Nipro Corporation Spraying device
WO2012004784A1 (en) 2010-07-04 2012-01-12 Medimop Medical Projects Ltd Vial adapter with syringe stabilizer
EP2591107A2 (en) 2010-07-06 2013-05-15 Aptateck Bio Ltd. Nucleic acid aptamer-based diagnostic methods with novel techniques for signal enhancement
US8721627B2 (en) 2010-07-22 2014-05-13 Carefusion 303, Inc. Needleless valve infection prevention and pre-opening device
USD654166S1 (en) 2010-08-06 2012-02-14 Neomed, Inc. Enteral connector
HUE034815T2 (en) 2010-08-25 2018-02-28 Baxalta GmbH Device for user reconstitution
US20120078214A1 (en) 2010-09-28 2012-03-29 Tyco Healthcare Group Lp Vial transfer needle assembly
USD669980S1 (en) 2010-10-15 2012-10-30 Medimop Medical Projects Ltd. Vented vial adapter
IL209102A0 (en) 2010-11-04 2011-01-31 Medimop Medical Projects Ltd Inline liquid drug medical device with handle operated flow control member
IL209290A0 (en) 2010-11-14 2011-01-31 Medimop Medical Projects Ltd Inline liquid drug medical device having rotary flow control member
EP2462913A1 (en) 2010-12-10 2012-06-13 Fresenius Medical Care Deutschland GmbH Insert and vial for the infusion of liquids
JP5670242B2 (ja) 2011-03-29 2015-02-18 テルモ株式会社 薬剤調製用具
USD657461S1 (en) 2011-04-04 2012-04-10 Cook Medical Technologies Llc Biopsy needle tip
EP2510914B1 (en) 2011-04-12 2014-08-27 F. Hoffmann-La Roche AG Connector device
US20120265163A1 (en) 2011-04-14 2012-10-18 Marc Bunjiun Cheng Coupling system to transfer material between containers
IL212420A0 (en) 2011-04-17 2011-06-30 Medimop Medical Projects Ltd Liquid drug transfer assembly
USD690418S1 (en) 2011-05-02 2013-09-24 Carmel Pharma Ab Medical device
WO2012150587A1 (en) 2011-05-03 2012-11-08 Sabiedriba Ar Ierobezotu Atbildibu "Sdmd" Vial adaptor
FR2975896B1 (fr) 2011-06-06 2014-06-06 Biocorp Rech Et Dev Dispositif de connexion entre un recipient et un contenant, procede d'assemblage et d'utilisation d'un tel dispositif
US20140221940A1 (en) 2011-06-17 2014-08-07 Tau Tona Group LP Needle for delivery of dermal filler threads
USD673673S1 (en) 2011-07-11 2013-01-01 Hsien-Tsung Wang Transparent Y-type of intravenous drip infusion set
USD674084S1 (en) 2011-07-21 2013-01-08 Mtp Medical Technical Promotion Gmbh Puncture cannula
US20140194854A1 (en) 2011-08-29 2014-07-10 Sid Technologies Llc Subcutaneous and intradermal patch infusers
USD681230S1 (en) 2011-09-08 2013-04-30 Yukon Medical, Llc Shroud
IL215699A0 (en) 2011-10-11 2011-12-29 Medimop Medical Projects Ltd Liquid drug reconstitution assemblage for use with iv bag and drug vial
USD711516S1 (en) 2011-12-09 2014-08-19 John Guest International Limited Fluid connector
USD720452S1 (en) 2011-12-15 2014-12-30 Mark Jordan Syringe connection hub
AU344164S (en) 2012-02-02 2012-09-04 Terumo Corp Safety device for indwelling needle
USD720451S1 (en) 2012-02-13 2014-12-30 Medimop Medical Projects Ltd. Liquid drug transfer assembly
USD674088S1 (en) 2012-02-13 2013-01-08 Medimop Medical Projects Ltd. Vial adapter
US20150013835A1 (en) 2012-02-29 2015-01-15 Sanofi-Aventis Deutschland Gmbh Extraction device for a single extraction of a medicament from a container
ES2905224T3 (es) 2012-03-05 2022-04-07 Becton Dickinson Co Equipo de transferencia con aguja flotante para reconstitución de fármacos
US20130253448A1 (en) 2012-03-09 2013-09-26 Steven Baron Hypodermic Needle With Multiple Dispersement Openings
US9072827B2 (en) 2012-03-26 2015-07-07 Medimop Medical Projects Ltd. Fail safe point protector for needle safety flap
IL219065A0 (en) 2012-04-05 2012-07-31 Medimop Medical Projects Ltd Fluid transfer device with manual operated cartridge release arrangement
IL219222A0 (en) 2012-04-17 2012-07-31 Medimop Medical Projects Ltd Quick release vial adapter
ITRM20120169A1 (it) 2012-04-19 2013-10-20 Consiglio Nazionale Ricerche Dispositivo di rilascio di specie chimiche a controllo ottico
JP5888606B2 (ja) 2012-06-18 2016-03-22 ニプロ株式会社 薬剤調製器具
IL221634A0 (en) 2012-08-26 2012-12-31 Medimop Medical Projects Ltd Universal drug vial adapter
IL221635A0 (en) 2012-08-26 2012-12-31 Medimop Medical Projects Ltd Drug vial mixing and transfer device for use with iv bag and drug vial
WO2014041529A1 (en) 2012-09-13 2014-03-20 Medimop Medical Projects Ltd Telescopic female drug vial adapter
EP2922590B1 (en) 2012-11-21 2020-02-05 Amgen Inc. Drug delivery device
ES2778867T3 (es) 2012-11-30 2020-08-12 Becton Dickinson & Co Ltd Adaptador de perfusión para dispositivo de transferencia de medicamentos
USD717406S1 (en) 2012-12-10 2014-11-11 Enviro Water Solutions, Inc. Backwash fitting
MX360830B (es) 2012-12-17 2018-11-16 Unitract Syringe Pty Ltd Adaptadores de frasco.
USD714935S1 (en) 2013-01-10 2014-10-07 Fuso Pharmaeutical Industries, Ltd. Adapter for connecting a needle to a syringe
USD733291S1 (en) 2013-01-15 2015-06-30 Hsien-Tsung Wang Depressible plug for vial
US9089475B2 (en) 2013-01-23 2015-07-28 Icu Medical, Inc. Pressure-regulating vial adaptors
USD732664S1 (en) 2013-02-25 2015-06-23 B. Braun Melsungen Ag Proximal catheter hub body
USD738494S1 (en) 2013-03-05 2015-09-08 Ikashmore Pty Ltd Blood collection safety device
USD733292S1 (en) 2013-03-10 2015-06-30 Rocomp Global, Llc Energy guide
US9308020B2 (en) 2013-03-14 2016-04-12 Cook Medical Technologies Llc Tri-fluted vascular access needle
USD733293S1 (en) 2013-03-15 2015-06-30 Rocomp Global, Llc Energy guide
USD720850S1 (en) 2013-03-15 2015-01-06 Sanovas, Inc. Catheter hub
IL225734A0 (en) 2013-04-14 2013-09-30 Medimop Medical Projects Ltd A ready-to-use medicine vial device including a medicine vial closure, and a medicine vial closure for it
GB201307385D0 (en) 2013-04-24 2013-06-05 Star Syringe Ltd Syringes
KR200486088Y1 (ko) 2013-08-07 2018-04-02 메디모프 메디컬 프로젝트스 리미티드. 주입 액체 용기와 함께 사용하기 위한 액체 전달 장치
CA3008509C (en) 2013-09-23 2020-11-10 Becton, Dickinson And Company Ltd. Piercing member for container access device
AU353353S (en) 2013-10-02 2014-01-21 Terumo Corp Medical syringe
CA2929473C (en) 2013-11-06 2019-06-04 Becton Dickinson and Company Limited Medical connector having locking engagement
US10391031B2 (en) 2013-11-06 2019-08-27 Becton Diskinson and Company Limited Adapter for vial access device
US20150305770A1 (en) 2014-03-12 2015-10-29 Epicardial Frontiers, LLC System and method of image guided pericardial procedures including pericardioscopy, pericardial ablation, pericardial material delivery, pericardial tissue grasping and manipulation, pericardial lead placement, and pericardial surgical fastener placement
USD794183S1 (en) 2014-03-19 2017-08-08 Medimop Medical Projects Ltd. Dual ended liquid transfer spike
USD750235S1 (en) 2014-03-19 2016-02-23 ERBE-USA, Inc. Endoscope connector
EP3714861A1 (en) 2014-04-21 2020-09-30 Becton Dickinson and Company Limited System for closed transfer of fluids and membrane arrangements for use thereof
ES2948711T3 (es) 2014-04-21 2023-09-18 Becton Dickinson & Co Ltd Adaptador de jeringuilla con movimiento combinado de desacoplamiento
CN107073211B (zh) 2014-08-14 2021-01-05 韦贝尔Cds公司 具有可选择的流动通道和密封部的注射器
USD757933S1 (en) 2014-09-11 2016-05-31 Medimop Medical Projects Ltd. Dual vial adapter assemblage
JP6368603B2 (ja) 2014-09-25 2018-08-01 テルモ株式会社 消毒キャップ
CN115414253A (zh) 2015-01-09 2022-12-02 贝克顿·迪金森有限公司 输注转接器
WO2016205626A1 (en) 2015-06-18 2016-12-22 Neomed, Inc. Syringe-to-syringe male-male coupler

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000262497A (ja) * 1999-03-16 2000-09-26 Sekisui Chem Co Ltd 分注器具、分注システム及び分注方法
CN1802143A (zh) * 2003-06-06 2006-07-12 巴克斯特国际公司 重新组配装置及其使用方法
CN101588780A (zh) * 2006-12-19 2009-11-25 卡迪纳尔健康303公司 用于药瓶进出的压力平衡设备
CN102711712A (zh) * 2010-02-24 2012-10-03 麦迪麦珀医疗工程有限公司 具有通风布置的流体转移组合件
US8753325B2 (en) * 2010-02-24 2014-06-17 Medimop Medical Projects, Ltd. Liquid drug transfer device with vented vial adapter
WO2013128444A1 (en) * 2012-03-02 2013-09-06 Medeq Llc Two way fluid control device
CN103585014A (zh) * 2012-07-13 2014-02-19 贝克顿·迪金森有限公司 有压力平衡和密闭药物传输系统的瓶接入装置及其用法

Also Published As

Publication number Publication date
IL262766B (en) 2022-02-01
IL245803A0 (en) 2016-08-31
JP2019519287A (ja) 2019-07-11
JP6636182B2 (ja) 2020-01-29
US20190336393A1 (en) 2019-11-07
EP3463250A1 (en) 2019-04-10
IL262766A (en) 2018-12-31
EP3463250B1 (en) 2020-04-01
CN109310573A (zh) 2019-02-05
WO2017203512A1 (en) 2017-11-30
US10765604B2 (en) 2020-09-08

Similar Documents

Publication Publication Date Title
CN109310573B (zh) 包括通气式药瓶转接器和通气式液体瓶转接器的双瓶转接器组合件
US10772797B2 (en) Liquid drug transfer devices for use with intact discrete injection vial release tool
CN109152699B (zh) 包括相同的成对的小瓶转接器的双瓶转接器组合件
CN108601706B (zh) 具有用于保证正确使用的快速释放药瓶转接器的药瓶转接器组件
US10278897B2 (en) Dual vial adapter assemblage including drug vial adapter with self-sealing access valve
EP3494951B1 (en) System for closed transfer of fluids
US20050137523A1 (en) Medicament administration apparatus
US20090082750A1 (en) Fluid transfer devices for use with cartridges
US20150231034A1 (en) Telescopic female drug vial adapter
CN111295171B (zh) 包括双排气母瓶适配器的双瓶适配器组件
EP3911292B1 (en) Liquid transfer devices for use with intravenous (iv) bottles

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant