CN101742988A - 具有改进壳层的微胶囊 - Google Patents

具有改进壳层的微胶囊 Download PDF

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Publication number
CN101742988A
CN101742988A CN200780029069A CN200780029069A CN101742988A CN 101742988 A CN101742988 A CN 101742988A CN 200780029069 A CN200780029069 A CN 200780029069A CN 200780029069 A CN200780029069 A CN 200780029069A CN 101742988 A CN101742988 A CN 101742988A
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Prior art keywords
oil
microcapsules
gelatin
shell
polymer component
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Pending
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CN200780029069A
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English (en)
Chinese (zh)
Inventor
J·宇赖
C·J·巴罗
W·张
C·严
J·M·柯蒂斯
S·莫尔顿
N·B·乔格本诺
L·A·韦伯
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DSM NUTRITIONAL Co Ltd
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Ocean Nutrition Canada Ltd
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Publication date
Application filed by Ocean Nutrition Canada Ltd filed Critical Ocean Nutrition Canada Ltd
Priority to CN201710542979.9A priority Critical patent/CN107362154B/zh
Publication of CN101742988A publication Critical patent/CN101742988A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Botany (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CN200780029069A 2006-06-05 2007-06-04 具有改进壳层的微胶囊 Pending CN101742988A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710542979.9A CN107362154B (zh) 2006-06-05 2007-06-04 具有改进壳层的微胶囊

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US81102406P 2006-06-05 2006-06-05
US60/811,024 2006-06-05
US83705006P 2006-08-11 2006-08-11
US60/837,050 2006-08-11
US87975907P 2007-01-10 2007-01-10
US60/879,759 2007-01-10
PCT/IB2007/003358 WO2008017962A2 (en) 2006-06-05 2007-06-04 Microcapsules with improved shells

Related Child Applications (1)

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CN201710542979.9A Division CN107362154B (zh) 2006-06-05 2007-06-04 具有改进壳层的微胶囊

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CN101742988A true CN101742988A (zh) 2010-06-16

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CN200780029069A Pending CN101742988A (zh) 2006-06-05 2007-06-04 具有改进壳层的微胶囊
CN201710542979.9A Expired - Fee Related CN107362154B (zh) 2006-06-05 2007-06-04 具有改进壳层的微胶囊

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US (1) US9056058B2 (https=)
EP (1) EP2040682B1 (https=)
JP (2) JP5979697B2 (https=)
KR (3) KR101994513B1 (https=)
CN (2) CN101742988A (https=)
AU (1) AU2007282922B2 (https=)
CA (1) CA2654031C (https=)
ES (1) ES2644753T3 (https=)
MX (1) MX306461B (https=)
NZ (2) NZ596403A (https=)
PL (1) PL2040682T3 (https=)
WO (1) WO2008017962A2 (https=)

Cited By (23)

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CN102302160A (zh) * 2011-09-07 2012-01-04 黑龙江省乳品工业技术开发中心 一种婴儿双歧杆菌微胶囊的制备方法
CN104304838A (zh) * 2014-10-29 2015-01-28 大连医诺生物有限公司 一种耐受机械搅拌的高载油营养脂质微囊粉的制备方法
CN104334032A (zh) * 2012-05-24 2015-02-04 弗门尼舍有限公司 混合凝聚胶囊
CN104619187A (zh) * 2012-04-12 2015-05-13 Idcaps公司 含有可氧化的活性物的微胶囊,和制备其的方法
CN104839423A (zh) * 2014-11-13 2015-08-19 吉林农业大学 一种改性乳清蛋白的制备方法
CN105053325A (zh) * 2015-07-27 2015-11-18 福建永生活力生物工程有限公司 一种微胶囊玛咖茶及其制备方法
CN105558354A (zh) * 2016-01-26 2016-05-11 武汉轻工大学 饲用鱼油微胶囊及其制备工艺
CN105980511A (zh) * 2014-02-14 2016-09-28 日立化成株式会社 糖醇微胶囊、浆料及树脂成型物
CN106174440A (zh) * 2016-07-05 2016-12-07 南昌大学 一种多分子层可控营养物缓释纳米乳凝胶的制备方法
CN107048421A (zh) * 2017-03-28 2017-08-18 常州大学 一种抗氧化微胶囊壁材的制备方法
CN107105693A (zh) * 2014-12-23 2017-08-29 赢创德固赛有限公司 用于增加包含多不饱和ω‑6脂肪酸的组合物的稳定性的方法
CN107105746A (zh) * 2014-12-23 2017-08-29 赢创德固赛有限公司 用于增加包含多不饱和ω‑3脂肪酸的组合物的稳定性的方法
CN107847895A (zh) * 2015-05-20 2018-03-27 拉姆博松有限公司 胶囊
CN108813616A (zh) * 2018-07-05 2018-11-16 河北东之星生物科技股份有限公司 一种制备叶黄素水溶性微乳液的方法
CN109528683A (zh) * 2018-12-13 2019-03-29 浙江华康药业股份有限公司 一种阿拉伯糖定点释放对肠内产丁酸菌的调控方法
CN109700032A (zh) * 2018-12-27 2019-05-03 湖北工业大学 一种基于全水相复合凝聚的益生菌微胶囊及其制备方法
CN109805412A (zh) * 2019-02-01 2019-05-28 安徽大学 一种复合益生菌肠道靶向控释体系及其制备方法
CN110483838A (zh) * 2015-05-29 2019-11-22 赛鲁斯股份有限公司 包封的聚合引发剂、聚合体系以及使用所述体系的方法
CN111568881A (zh) * 2020-06-08 2020-08-25 广东悦生生物科技有限公司 一种核壳体缓释氨基酸补剂及其制备方法
CN115349627A (zh) * 2022-07-27 2022-11-18 勃源生物科技(上海)有限公司 无腥味鱼油微鸡蛋模型及其制备方法
CN116322568A (zh) * 2020-12-23 2023-06-23 弗门尼舍有限公司 制备微胶囊的方法
CN117837759A (zh) * 2023-12-26 2024-04-09 大连医诺生物股份有限公司 一种具有高阻隔抗粉碎的多层多核长链多不饱和脂肪酸微囊粉的配方、其制备方法及应用
WO2025055959A1 (en) * 2023-09-12 2025-03-20 Bing Biotech Limited Encapsulation of dual-enzyme composition for preventing, treating and/or alleviating veisalgia and symptoms associated therewith

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US6974592B2 (en) * 2002-04-11 2005-12-13 Ocean Nutrition Canada Limited Encapsulated agglomeration of microcapsules and method for the preparation thereof
JP4833553B2 (ja) * 2002-11-04 2011-12-07 オーシャン・ニュートリション・カナダ・リミテッド 複数の殻を有するマイクロカプセル及びそれらの調製方法
US9968120B2 (en) 2006-05-17 2018-05-15 Dsm Nutritional Products Ag Homogenized formulations containing microcapsules and methods of making and using thereof
EP2007224A2 (en) * 2006-04-07 2008-12-31 Ocean Nutrition Canada Limited Emulsions and microcapsules with substances having low interfacial tension, methods of making and using thereof
EP2040682B1 (en) 2006-06-05 2017-07-26 DSM Nutritional Products AG Microcapsules with improved shells
ES2604081T3 (es) 2007-01-10 2017-03-02 Dsm Nutritional Products Ag Microcápsulas que incluyen proteína de guisante
US20080292692A1 (en) * 2007-05-21 2008-11-27 Shira Pilch Impermeable Capsules
KR101007865B1 (ko) * 2007-06-18 2011-01-14 연세대학교 산학협력단 키토산 및 피틴산을 포함하는 서방성 키토산 캡슐
WO2009071286A1 (en) * 2007-12-05 2009-06-11 Dsm Ip Assets B.V. Pulverous formulation of a fat-soluble active ingredient
BRPI0821359A2 (pt) * 2007-12-21 2015-06-16 Merck Patent Ges Mit Beschränkter Haftung Microcápsulas de lipídeos sólidas contendo hormônio de crescimento no núcleo sólido interno
EP2410879B8 (en) * 2009-03-26 2019-08-14 Advanced BioNutrition Corp. Microencapsulation of bioactive substances and methods of making the same
CH701000A1 (de) * 2009-04-30 2010-11-15 U Nica Technology Ag Bacteriorhodopsin enthaltende Mikrokapseln und Verfahren zu deren Herstellung.
GB0909909D0 (en) * 2009-06-09 2009-07-22 Chrisal Nv Microcapsules containing microrgnisms
US9205395B2 (en) * 2009-10-15 2015-12-08 Encapsys, Llc Encapsulation
FR2955258A1 (fr) * 2010-01-20 2011-07-22 Biopharmex Holding Ltd Composition injectable
US8846863B2 (en) 2010-04-30 2014-09-30 University Of Tennessee Research Foundation Heat stable protein ingredients
AU2011305572B2 (en) * 2010-09-20 2016-08-04 Diane Goll Microencapsulation process and product
WO2013032447A1 (en) * 2011-08-30 2013-03-07 Empire Technology Development Llc Ferrocene /carbon dioxide releasing system
US10988618B2 (en) 2011-09-23 2021-04-27 Dystar Hilton Davis Corp. Self-assembled nano-structured particle and methods for preparing
EP2758037B1 (en) * 2011-09-23 2018-01-24 Emerald Hilton Davis, LLC Self-assembled nano-structure particle and method for preparing
AU2012380676B2 (en) 2012-05-21 2016-02-18 Dsm Nutritional Products Ag Compositions and methods for increasing the stability of food product additives
US8617610B2 (en) * 2012-05-21 2013-12-31 Dsm Nutritional Products Ag Compositions and methods for increasing the stability of food product additives
WO2014000749A1 (en) * 2012-06-27 2014-01-03 El-Ezabi Ahmed Esam Entrapment of oils and immobilization of proteins using novel matrices
CN104507324A (zh) 2012-07-31 2015-04-08 帝斯曼营养产品股份公司 使用绿茶提取物抗氧化剂精制油
WO2014078912A1 (en) * 2012-11-26 2014-05-30 Progel Pty Ltd Coating composition
DK2925300T6 (da) 2012-11-29 2021-02-08 Progel Pty Ltd Mikropartikler omfattende et probiotikum, et reagens, der kan tværbindes, et denatureret protein, et polyolplastificeringsmiddel og trehalose
US10449157B2 (en) 2013-06-12 2019-10-22 Anabio Technologies Limited Process for producing microcapsules comprising an active component encapsulated, protected and stabilised within a protein shell
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