CN101485897B - 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料 - Google Patents

生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料 Download PDF

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Publication number
CN101485897B
CN101485897B CN200810032631.6A CN200810032631A CN101485897B CN 101485897 B CN101485897 B CN 101485897B CN 200810032631 A CN200810032631 A CN 200810032631A CN 101485897 B CN101485897 B CN 101485897B
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CN
China
Prior art keywords
starch
modified starch
hemostatic
biocompatible
tissue
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Ceased
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CN200810032631.6A
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English (en)
Chinese (zh)
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CN101485897A (zh
Inventor
纪欣
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Beijing Universal Likang Technology Co ltd
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Individual
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40885597&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN101485897(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to CN201510225339.6A priority Critical patent/CN104888263B/zh
Priority to CN200810032631.6A priority patent/CN101485897B/zh
Priority to CN201510225340.9A priority patent/CN104888264B/zh
Application filed by Individual filed Critical Individual
Priority to US12/228,029 priority patent/US20090062233A1/en
Priority to JP2010542290A priority patent/JP5931339B2/ja
Priority to EP17160575.1A priority patent/EP3199025A1/en
Priority to PCT/US2009/000227 priority patent/WO2009091549A1/en
Priority to EP09701521.8A priority patent/EP2203053B1/en
Publication of CN101485897A publication Critical patent/CN101485897A/zh
Priority to US13/740,033 priority patent/US8575132B2/en
Priority to US13/894,396 priority patent/US9687501B2/en
Priority to US14/018,895 priority patent/US8912168B2/en
Priority to JP2014064241A priority patent/JP5883895B2/ja
Priority to US14/322,861 priority patent/US9533005B2/en
Publication of CN101485897B publication Critical patent/CN101485897B/zh
Application granted granted Critical
Priority to US15/229,080 priority patent/US20160339143A1/en
Priority to US15/359,255 priority patent/US10076590B2/en
Priority to US15/427,801 priority patent/US10195312B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0076—Sprayable compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/041—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN200810032631.6A 2007-08-09 2008-01-14 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料 Ceased CN101485897B (zh)

Priority Applications (16)

Application Number Priority Date Filing Date Title
CN201510225339.6A CN104888263B (zh) 2008-01-14 2008-01-14 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料
CN200810032631.6A CN101485897B (zh) 2008-01-14 2008-01-14 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料
CN201510225340.9A CN104888264B (zh) 2008-01-14 2008-01-14 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料
US12/228,029 US20090062233A1 (en) 2007-08-09 2008-08-08 Modified starch material of biocompatible hemostasis
JP2010542290A JP5931339B2 (ja) 2008-01-14 2009-01-13 生物相容性の止血、癒着防止、癒合促進、外科密封可能な変性澱粉材料
EP17160575.1A EP3199025A1 (en) 2008-01-14 2009-01-13 Modified starch material of biocompatible hemostasis
PCT/US2009/000227 WO2009091549A1 (en) 2008-01-14 2009-01-13 Modified starch material of biocompatible hemostasis
EP09701521.8A EP2203053B1 (en) 2008-01-14 2009-01-13 Modified starch material of biocompatible hemostasis
US13/740,033 US8575132B2 (en) 2007-08-09 2013-01-11 Modified starch material of biocompatible hemostasis
US13/894,396 US9687501B2 (en) 2007-08-09 2013-05-14 Modified starch material of biocompatible hemostasis
US14/018,895 US8912168B2 (en) 2007-08-09 2013-09-05 Modified starch material of biocompatible hemostasis
JP2014064241A JP5883895B2 (ja) 2008-01-14 2014-03-26 生物相容性の止血、癒着防止、癒合促進、外科密封可能な変性澱粉材料
US14/322,861 US9533005B2 (en) 2007-08-09 2014-07-02 Modified starch material of biocompatible hemostasis
US15/229,080 US20160339143A1 (en) 2007-08-09 2016-08-04 Modified Starch Material of Biocompatible Hemostasis
US15/359,255 US10076590B2 (en) 2007-08-09 2016-11-22 Modified starch material of biocompatible hemostasis
US15/427,801 US10195312B2 (en) 2007-08-09 2017-02-08 Modified starch material of biocompatible hemostasis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN200810032631.6A CN101485897B (zh) 2008-01-14 2008-01-14 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN201510225340.9A Division CN104888264B (zh) 2008-01-14 2008-01-14 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料
CN201510225339.6A Division CN104888263B (zh) 2008-01-14 2008-01-14 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料

Publications (2)

Publication Number Publication Date
CN101485897A CN101485897A (zh) 2009-07-22
CN101485897B true CN101485897B (zh) 2015-05-20

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ID=40885597

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Application Number Title Priority Date Filing Date
CN200810032631.6A Ceased CN101485897B (zh) 2007-08-09 2008-01-14 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料
CN201510225339.6A Active CN104888263B (zh) 2008-01-14 2008-01-14 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料
CN201510225340.9A Active CN104888264B (zh) 2008-01-14 2008-01-14 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN201510225339.6A Active CN104888263B (zh) 2008-01-14 2008-01-14 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料
CN201510225340.9A Active CN104888264B (zh) 2008-01-14 2008-01-14 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料

Country Status (4)

Country Link
EP (2) EP3199025A1 (enExample)
JP (2) JP5931339B2 (enExample)
CN (3) CN101485897B (enExample)
WO (1) WO2009091549A1 (enExample)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
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CN101485897B (zh) 2008-01-14 2015-05-20 纪欣 生物相容性止血、防粘连、促愈合、外科封闭的变性淀粉材料
KR101062068B1 (ko) * 2008-12-01 2011-09-02 포항공과대학교 산학협력단 유착방지용 조성물
CN101669964B (zh) * 2009-09-30 2011-07-06 大连大学 一种外科手术防粘连剂及其制备方法
JP5767239B2 (ja) 2009-12-04 2015-08-19 マグレ アクティエボラーグ 内因性荷電リガンドを有する加水分解澱粉の微小球
CN102397587A (zh) * 2010-09-08 2012-04-04 舒朝锋 一种宫腔防粘连材料及其制备工艺和用途
CN102406956B (zh) * 2011-03-09 2013-09-25 天津爱勒易医药材料有限公司 一种淀粉止血微球及其制备方法
JP5835751B2 (ja) * 2011-04-01 2015-12-24 珠海奥托沙医薬科技有限公司 医療用吸収性骨創傷止血材及びその調製方法
CN103055343B (zh) * 2011-10-19 2014-07-30 袁暾 一种马铃薯淀粉-透明质酸复合止血粉及其制备方法
CN107617123A (zh) * 2012-02-16 2018-01-23 技术创新动力基金（以色列）有限合伙公司 用于形成生物粘附基质的制剂和试剂盒
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CN103041448B (zh) * 2013-01-17 2015-09-23 苏州博创同康生物工程有限公司 一种复合多糖止血材料及其制备方法和应用
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CN103263434B (zh) * 2013-06-03 2014-11-26 张岩 一种创口冲洗、外科手术用防粘连液及制备方法和应用
DE102013211316A1 (de) 2013-06-17 2014-12-18 Aesculap Ag Hämostyptikum
CN103487300B (zh) * 2013-08-14 2016-07-13 武汉工程大学 高吸水树脂吸水速率的测试方法
CN104546893A (zh) * 2014-01-07 2015-04-29 北京大清生物技术有限公司 一种可生物降解吸收的止血组合物
KR101864465B1 (ko) * 2014-01-21 2018-06-04 재단법인 유타 인하 디디에스 및 신의료기술개발 공동연구소 의료용 도관을 통한 생체 내 투여성 마이크로 입자
DE102014202578A1 (de) 2014-02-12 2015-08-13 Aesculap Ag Medizinisches Produkt und Verfahren zu seiner Herstellung
CN103865108B (zh) * 2014-03-28 2016-08-31 甘肃丰收农业科技有限公司 一种用于食品生产中的复合变性淀粉的制备方法
CN105194712A (zh) * 2014-05-29 2015-12-30 成都吉泰医疗器械有限公司 一种止血材料及其制备方法
CN105412975B (zh) * 2014-09-18 2019-05-31 苏州安德佳生物科技有限公司 一种生物相容性止血制品及其制备方法
CN104398339A (zh) * 2014-09-26 2015-03-11 史跃 一种可吸收微孔真空多聚糖止血贴及其制备方法
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CN104327310B (zh) * 2014-11-24 2017-01-04 江苏德威兰医疗器械有限公司 一种超声波工艺处理的防粘连膜及其制备方法
CA2968104A1 (en) 2014-12-19 2016-06-23 Baxter International Inc. Flowable hemostatic composition
CN105770968A (zh) * 2014-12-23 2016-07-20 重庆联佰博超医疗器械有限公司 一种可吸收性淀粉止血粉及其制备方法、应用
CN104721874B (zh) * 2014-12-23 2017-09-22 重庆联佰博超医疗器械有限公司 一种多糖止血粉及其制备方法、应用
CN105770965A (zh) * 2014-12-23 2016-07-20 重庆联佰博超医疗器械有限公司 一种可吸收性淀粉止血粉及其制备方法、应用
CN105770966A (zh) * 2014-12-23 2016-07-20 重庆联佰博超医疗器械有限公司 一种可吸收性淀粉止血粉及其制备方法、应用
CN104958789B (zh) * 2015-07-27 2018-01-23 大连大学 防止手术后粘连的复合膜的制备方法
CN104958790B (zh) * 2015-07-27 2018-01-23 大连大学 防止手术后粘连的复合膜
CN105148328B (zh) * 2015-08-29 2018-01-26 北京诺康达医药科技有限公司 一种医用组织防护清洗液及其制备方法和应用
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US10137221B2 (en) 2015-11-08 2018-11-27 Omrix Biopharmaceuticals Ltd. Hemostatic mixture of cellulose-based short and long fibers
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DE102016008533A1 (de) 2016-07-18 2018-01-18 PlantTec Medical GmbH Arzneimittel
CN106377792B (zh) * 2016-09-29 2019-12-03 江苏华能药业有限公司 复合微孔交联淀粉止血粉
KR101995909B1 (ko) * 2016-10-19 2019-08-08 대가파우더시스템 주식회사 지혈용 분말의 제조 방법
KR101887282B1 (ko) * 2016-12-07 2018-08-09 서울대학교산학협력단 바이오 히터
CN108261560B (zh) * 2017-01-03 2020-12-08 张家港唯瀚生物科技有限公司 一种含变性淀粉纳米粒的可降解吸收止血材料及其应用
CN108498879B (zh) 2017-02-28 2021-12-28 苏州安德佳生物科技有限公司 黏膜下注射用组合物和试剂组合及其应用
CN107029279A (zh) * 2017-03-08 2017-08-11 安徽省伟业净化设备有限公司 一种高倍吸水抗菌止血用海绵
CN106806936A (zh) * 2017-03-29 2017-06-09 武汉医佳宝生物材料有限公司 一种淀粉基复合止血粉的制备
CN106913899A (zh) * 2017-04-26 2017-07-04 江苏华能药业有限公司 利用二次冷冻法制备植物多糖止血海绵
CN107335090B (zh) * 2017-07-11 2020-09-01 李徐奇 一种具有创面修复作用的生物相容性止血材料及其制备方法
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CN108159508B (zh) * 2018-01-03 2021-01-26 东南大学 一种防粘连医用水凝胶材料的制备方法
DE102018000009A1 (de) 2018-01-04 2019-03-07 PlantTec Medical GmbH Arzneimittel
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