CN101240022B - 含有抗磷脂酰肌醇蛋白聚糖3抗体的细胞生长抑制剂 - Google Patents
含有抗磷脂酰肌醇蛋白聚糖3抗体的细胞生长抑制剂 Download PDFInfo
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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| US7361336B1 (en) * | 1997-09-18 | 2008-04-22 | Ivan Bergstein | Methods of cancer therapy targeted against a cancer stem line |
| CN101240022B (zh) * | 2001-06-22 | 2012-07-18 | 中外制药株式会社 | 含有抗磷脂酰肌醇蛋白聚糖3抗体的细胞生长抑制剂 |
| JP4455324B2 (ja) * | 2002-05-23 | 2010-04-21 | サニーブルック ヘルスサイエンス センター | 肝細胞癌の診断 |
| AU2002338020A1 (en) * | 2002-09-04 | 2004-03-29 | Chugai Seiyaku Kabushiki Kaisha | Antibody against blood-solubilized n-terminal peptide in gpc3 |
| US20080008710A1 (en) * | 2003-09-04 | 2008-01-10 | Hiroyuki Aburatani | Therapeutic Agent And Diagnostic Agent For Cholangiocarcinoma |
| BRPI0506125B8 (pt) * | 2004-07-09 | 2021-05-25 | Chugai Pharmaceutical Co Ltd | anticorpo anti - glipicano 3, seu método de produção, polinucleotídeo, vetor e inibidor do crescimento de células |
| PL1800693T3 (pl) | 2004-08-24 | 2013-12-31 | Chugai Pharmaceutical Co Ltd | Terapia adiuwantowa z zastosowaniem przeciwciała przeciw glipikanowi 3 |
| WO2006046751A1 (ja) * | 2004-10-26 | 2006-05-04 | Chugai Seiyaku Kabushiki Kaisha | 糖鎖改変抗グリピカン３抗体 |
| DK3050963T3 (da) * | 2005-03-31 | 2019-12-09 | Chugai Pharmaceutical Co Ltd | Fremgangsmåde til fremstilling af polypeptid ved regulering af arrangement |
| JPWO2007015529A1 (ja) | 2005-08-03 | 2009-02-19 | パナソニック株式会社 | 基地局装置、通信端末装置、およびマルチキャリア通信方法 |
| US20070087005A1 (en) * | 2005-10-14 | 2007-04-19 | Lazar Gregory A | Anti-glypican-3 antibody |
| US7723043B2 (en) * | 2006-01-04 | 2010-05-25 | Picobella, Lp | Methods for screening for prostate cancer |
| DK2009101T3 (en) * | 2006-03-31 | 2018-01-15 | Chugai Pharmaceutical Co Ltd | Antibody modification method for purification of a bispecific antibody |
| EP2006381B1 (en) | 2006-03-31 | 2016-02-03 | Chugai Seiyaku Kabushiki Kaisha | Method for controlling blood pharmacokinetics of antibodies |
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| RU2010116756A (ru) | 2007-09-28 | 2011-11-10 | Чугаи Сейяку Кабусики Кайся (Jp) | Антитело против глипикана-3 с улучшенными кинетическими показателями в плазме |
| WO2009072604A1 (ja) * | 2007-12-05 | 2009-06-11 | Chugai Seiyaku Kabushiki Kaisha | 抗nr10抗体、およびその利用 |
| CL2009000647A1 (es) * | 2008-04-04 | 2010-06-04 | Chugai Pharmaceutical Co Ltd | Composicion farmaceutica para tratar o prevenir cancer hepatico que comprende una combinacion de un agente quimioterapeutico y un anticuerpo anti-glipicano 3; agente para atenuar un efecto secundario que comprende dicho anticuerpo; metodo para tratar o prevenir un cancer hepatico de un sujeto. |
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| US20120190049A1 (en) * | 2010-12-10 | 2012-07-26 | University Of Washington Through Its Center For Commercialization | Glypican-3 targeting of liver cancer cells using multifunctional nanoparticles |
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