CH649299A5 - Acides 1-oxo-1h-thiazolo(3,2-a)pyrimidine-2-carboxyliques et leurs derives. - Google Patents

Acides 1-oxo-1h-thiazolo(3,2-a)pyrimidine-2-carboxyliques et leurs derives. Download PDF

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Publication number
CH649299A5
CH649299A5 CH8567/80A CH856780A CH649299A5 CH 649299 A5 CH649299 A5 CH 649299A5 CH 8567/80 A CH8567/80 A CH 8567/80A CH 856780 A CH856780 A CH 856780A CH 649299 A5 CH649299 A5 CH 649299A5
Authority
CH
Switzerland
Prior art keywords
oxo
pyrimidine
ethyl
mixture
mmol
Prior art date
Application number
CH8567/80A
Other languages
English (en)
French (fr)
Inventor
Saul Bernard Kadin
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CH649299A5 publication Critical patent/CH649299A5/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
CH8567/80A 1979-11-23 1980-11-19 Acides 1-oxo-1h-thiazolo(3,2-a)pyrimidine-2-carboxyliques et leurs derives. CH649299A5 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9663179A 1979-11-23 1979-11-23

Publications (1)

Publication Number Publication Date
CH649299A5 true CH649299A5 (fr) 1985-05-15

Family

ID=22258306

Family Applications (1)

Application Number Title Priority Date Filing Date
CH8567/80A CH649299A5 (fr) 1979-11-23 1980-11-19 Acides 1-oxo-1h-thiazolo(3,2-a)pyrimidine-2-carboxyliques et leurs derives.

Country Status (35)

Country Link
JP (1) JPS5687586A (pt)
KR (1) KR830004322A (pt)
AR (2) AR228859A1 (pt)
AT (1) AT380883B (pt)
AU (1) AU520995B2 (pt)
BE (1) BE886319A (pt)
CA (1) CA1143731A (pt)
CH (1) CH649299A5 (pt)
CS (1) CS241476B2 (pt)
DD (1) DD154608A5 (pt)
DE (2) DE3050491C2 (pt)
DK (1) DK151811C (pt)
EG (1) EG14929A (pt)
ES (1) ES8203363A1 (pt)
FI (1) FI67706C (pt)
FR (1) FR2470132A1 (pt)
GB (1) GB2063862B (pt)
GR (1) GR72132B (pt)
GT (1) GT198066458A (pt)
HU (1) HU179091B (pt)
IE (1) IE50404B1 (pt)
IL (1) IL61535A (pt)
IN (1) IN154926B (pt)
IT (1) IT1209373B (pt)
LU (1) LU82950A1 (pt)
NL (1) NL182565C (pt)
NO (1) NO803521L (pt)
NZ (1) NZ195596A (pt)
PH (1) PH16666A (pt)
PL (1) PL132354B1 (pt)
PT (1) PT72090B (pt)
SE (1) SE448732B (pt)
SU (1) SU1042620A3 (pt)
YU (1) YU41953B (pt)
ZA (1) ZA807293B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8300728D0 (en) * 1983-01-12 1983-02-16 Erba Farmitalia Substituted carboxy-thiazolo / 3 2 - a / pyrimidine derivatives
US4457932A (en) * 1983-07-22 1984-07-03 Bristol-Myers Company Anti-ulcer agents
GB8422916D0 (en) * 1984-09-11 1984-10-17 May & Baker Ltd Compositions of matter
JP2690742B2 (ja) * 1987-03-30 1997-12-17 第一製薬株式会社 複素環アミン誘導体
ES2087072T3 (es) * 1988-03-28 1996-07-16 Janssen Pharmaceutica Nv Agentes para conservar o restablecer la salud de la piel.
TWI500623B (zh) * 2009-10-13 2015-09-21 Torrent Pharmaceuticals Ltd 新穎稠合噻唑及噁唑嘧啶酮

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1331059A (en) 1971-04-19 1973-09-19 Lilly Industries Ltd Pyrimidotriazinone compounds
US4041163A (en) * 1976-03-29 1977-08-09 Pfizer Inc. N-(5-Tetrazolyl)-4-oxo-4H-pyrimido(2,1-b)benzothiazole-3-carboxamide antiallergy agents
DE2810863A1 (de) * 1978-03-13 1979-09-27 Boehringer Mannheim Gmbh 1-oxo-1h-pyrimido eckige klammer auf 6,1-b eckige klammer zu benzthiazol-derivate und verfahren zu ihrer herstellung
US4223031A (en) * 1978-05-05 1980-09-16 Mead Johnson & Company Azolopyrimidinones

Also Published As

Publication number Publication date
JPS5687586A (en) 1981-07-16
FR2470132A1 (fr) 1981-05-29
GB2063862B (en) 1983-06-22
DE3043979A1 (de) 1981-09-03
PL228008A1 (pt) 1981-12-11
HU179091B (en) 1982-08-28
NL182565C (nl) 1988-04-05
SE448732B (sv) 1987-03-16
DK151811B (da) 1988-01-04
NL8006362A (nl) 1981-06-16
AR228859A1 (es) 1983-04-29
ATA570780A (de) 1985-12-15
ES497066A0 (es) 1982-04-01
CS782080A2 (en) 1985-06-13
YU295080A (en) 1983-06-30
IL61535A0 (en) 1980-12-31
FI803628L (fi) 1981-05-24
SE8008189L (sv) 1981-05-24
FI67706B (fi) 1985-01-31
FR2470132B1 (pt) 1983-07-29
GB2063862A (en) 1981-06-10
AR231296A1 (es) 1984-10-31
BE886319A (fr) 1981-05-25
NO803521L (no) 1981-05-25
PT72090A (en) 1980-12-01
DD154608A5 (de) 1982-04-07
GT198066458A (es) 1982-05-15
PL132354B1 (en) 1985-02-28
JPS617432B2 (pt) 1986-03-06
IL61535A (en) 1984-06-29
EG14929A (en) 1989-01-30
NL182565B (nl) 1987-11-02
IN154926B (pt) 1984-12-22
DK151811C (da) 1988-06-06
AT380883B (de) 1986-07-25
CS241476B2 (en) 1986-03-13
PT72090B (en) 1981-09-29
SU1042620A3 (ru) 1983-09-15
KR830004322A (ko) 1983-07-09
IE802418L (en) 1981-05-23
DK413180A (da) 1981-05-24
DE3043979C2 (de) 1986-08-21
FI67706C (fi) 1985-05-10
ES8203363A1 (es) 1982-04-01
IT1209373B (it) 1989-07-16
CA1143731A (en) 1983-03-29
GR72132B (pt) 1983-09-19
IT8026176A0 (it) 1980-11-21
DE3050491C2 (de) 1985-10-10
NZ195596A (en) 1984-05-31
AU520995B2 (en) 1982-03-11
IE50404B1 (en) 1986-04-16
PH16666A (en) 1983-12-13
LU82950A1 (fr) 1981-06-04
AU6459580A (en) 1981-05-28
ZA807293B (en) 1981-12-30
YU41953B (en) 1988-02-29

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