CH644615A5 - Androstan-carbothioate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. - Google Patents

Androstan-carbothioate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. Download PDF

Info

Publication number
CH644615A5
CH644615A5 CH98281A CH98281A CH644615A5 CH 644615 A5 CH644615 A5 CH 644615A5 CH 98281 A CH98281 A CH 98281A CH 98281 A CH98281 A CH 98281A CH 644615 A5 CH644615 A5 CH 644615A5
Authority
CH
Switzerland
Prior art keywords
group
hydroxy
methyl
diene
compounds
Prior art date
Application number
CH98281A
Other languages
German (de)
English (en)
Inventor
Gordon Hanley Phillipps
Brian Macdonald Bain
Christopher Williamson
Ian Philip Steeples
Stuart Bruce Laing
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CH644615A5 publication Critical patent/CH644615A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH98281A 1980-02-15 1981-02-13 Androstan-carbothioate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. CH644615A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8005174 1980-02-15
GB8013339 1980-04-23

Publications (1)

Publication Number Publication Date
CH644615A5 true CH644615A5 (de) 1984-08-15

Family

ID=26274505

Family Applications (2)

Application Number Title Priority Date Filing Date
CH3890/84A CH651307A5 (de) 1980-02-15 1981-02-13 Androsta-carbothiosaeuren und verfahren zu ihrer herstellung.
CH98281A CH644615A5 (de) 1980-02-15 1981-02-13 Androstan-carbothioate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH3890/84A CH651307A5 (de) 1980-02-15 1981-02-13 Androsta-carbothiosaeuren und verfahren zu ihrer herstellung.

Country Status (23)

Country Link
KR (1) KR850000969B1 (it)
AT (1) AT395427B (it)
AU (1) AU544517B2 (it)
BG (1) BG60700B2 (it)
CH (2) CH651307A5 (it)
CZ (1) CZ281275B6 (it)
DE (2) DE3153379C2 (it)
DK (1) DK147022C (it)
ES (5) ES499394A0 (it)
FI (1) FI70904C (it)
FR (2) FR2477156A1 (it)
HK (1) HK58385A (it)
IE (1) IE51394B1 (it)
IT (1) IT1170717B (it)
KE (1) KE3526A (it)
MX (1) MX9202717A (it)
MY (1) MY8500757A (it)
NL (2) NL191792C (it)
NZ (1) NZ196260A (it)
PT (1) PT72502B (it)
SE (1) SE452468B (it)
SG (1) SG36885G (it)
SK (1) SK403491A3 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA817929B (en) * 1980-12-22 1982-10-27 Upjohn Co 5alpha-and 5beta-androstane-17beta-carboxylates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1436549A (en) * 1972-06-15 1976-05-19 Glaxo Lab Ltd 17beta-mercaptocarbonyl-3alpha-hydroxy-steroids and their esters
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
GB1514476A (en) * 1974-08-30 1978-06-14 Glaxo Lab Ltd Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates
US4188385A (en) * 1978-04-05 1980-02-12 Syntex (U.S.A.) Inc. Thioetianic acid derivatives
GB1580517A (en) * 1978-04-06 1980-12-03 Fowler I Crutches

Also Published As

Publication number Publication date
FR2485542B1 (it) 1983-06-10
IE51394B1 (en) 1986-12-24
ES532055A0 (es) 1985-10-16
CZ281275B6 (cs) 1996-08-14
FI70904B (fi) 1986-07-18
SE8101010L (sv) 1981-08-16
NL191792C (nl) 1996-08-02
SK278140B6 (en) 1996-02-07
ES8305379A1 (es) 1983-04-01
AU544517B2 (en) 1985-06-06
IT8147792A0 (it) 1981-02-13
DE3153379C2 (it) 1992-11-19
ES8207194A1 (es) 1982-09-01
DK147022B (da) 1984-03-19
SK403491A3 (en) 1996-02-07
NL960029I1 (nl) 1997-02-03
DK147022C (da) 1984-08-27
HK58385A (en) 1985-08-16
IE810282L (en) 1981-08-15
KE3526A (en) 1985-06-07
AT395427B (de) 1992-12-28
NL191792B (nl) 1996-04-01
MY8500757A (en) 1985-12-31
ES524985A0 (es) 1985-01-01
ES499394A0 (es) 1982-09-01
AU6729881A (en) 1981-08-20
KR830005262A (ko) 1983-08-03
ATA67481A (de) 1992-05-15
PT72502A (en) 1981-03-01
SG36885G (en) 1985-11-15
PT72502B (en) 1982-02-05
DE3105307A1 (de) 1981-12-10
IT1170717B (it) 1987-06-03
NL8100707A (nl) 1981-09-16
ES8502447A1 (es) 1985-01-01
MX9202717A (es) 1992-06-30
ES518161A0 (es) 1984-01-16
BG60700B2 (bg) 1995-12-29
SE452468B (sv) 1987-11-30
CZ403491A3 (en) 1994-03-16
FI70904C (fi) 1986-10-27
CH651307A5 (de) 1985-09-13
NL960029I2 (nl) 1997-04-01
ES8600936A1 (es) 1985-10-16
FR2485542A1 (fr) 1981-12-31
KR850000969B1 (ko) 1985-07-02
FI810444L (fi) 1981-08-16
DE3105307C2 (it) 1988-09-29
ES509539A0 (es) 1983-04-01
FR2477156A1 (fr) 1981-09-04
NZ196260A (en) 1983-11-30
FR2477156B1 (it) 1984-11-16
DK62381A (da) 1981-08-16
ES8402317A1 (es) 1984-01-16

Similar Documents

Publication Publication Date Title
US4335121A (en) Androstane carbothioates
EP0004975B1 (de) Corticoid-17-Alkylcarbonate, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel gegen Dermatosen
DE2707336C2 (it)
EP0000742B1 (de) Corticoid-17-Alkylcarbonate und Verfahren zu deren Herstellung und diese enthaltende Mittel
GB2088877A (en) Androstane 17 beta carbothioates
DE1443957B1 (de) 9 alpha-Chlor- bzw. 9 alpha-Fluor-16 beta-methyl-prednisolon-17,21-diester und ein Verfahren zu deren Herstellung
EP0135476B1 (de) Steroid Carbonsäureester
DE2336633A1 (de) Steroidverbindungen
DE2655570A1 (de) Neue polyhalogensteroide und verfahren zu ihrer herstellung
DE2538595A1 (de) Steroidverbindungen
DE2743069C2 (de) 21-Chlor-6α-fluor-9α-halogen-11β-hydroxy-16β-methyl-17α-propionyloxy-pregna-1,4-dien-3,20-dion-Verbindungen, Verfahren zu ihrer Herstellung und pharmazeutische Präparate, welche diese Verbindungen enthalten
DE3105307C2 (it)
AT395428B (de) Verfahren zur herstellung von neuen androstancarbothioaten
DE69609201T2 (de) 21-[2-oxo-tetrahydrofuran]-thio pregnan derivative, ein verfahren zu ihrer herstellung und pharmazeutische präparate davon
DE3401680A1 (de) 6(alpha),16ss-dimethylkortikoide
DE2340656A1 (de) Steroidverbindungen
DE1518994A1 (de) Verfahren zur Herstellung von neuen Beta,10Alpha-Steroiden
DE2365992C3 (de) 6α-Fluor-17,21-dihydroxy-16β-methylpregna-4,9(11)-dien-3,20-dion-17,21-diacetat und Verfahren zu dessen Herstellung
AT401521B (de) Verfahren zur herstellung von neuen androstancarbothioaten
EP0077541B1 (de) Delta-1,3,5-3-Chlor-11-Beta,16-Alpha,17-Alpha,21-tetra-(hydroxy)-pregnan-20-on-16,17-acetonidderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
EP0011121B1 (de) Hydrocortisonester, diese enthaltende pharmazeutische Zubereitungen und Verfahren zu ihrer Herstellung
CH639669A5 (en) Oxoandrostadiene derivatives
DE1443957C (de) 9 alpha-Chlor- bzw. 9 alpha-Fluor-. 16 beta-methyl-prednisolon-17,21-diester und ein Verfahren zu deren Herstellung
DE2630270A1 (de) 21-acetale und gemischte 21-acetale von steroid-21-aldehyden, zwischenprodukte und verfahren zur herstellung derselben
EP0005758A1 (de) Verfahren zum Aufbau der Hydroxyacetyl-Seitenkette von Steroiden des Pregnan-Typs, neue 21-Hydroxy-20-oxo-17alpha-pregnan-Verbindungen und pharmazeutische Präparate enthaltend dieselben

Legal Events

Date Code Title Description
SPCF Supplementary protection certificate filed

Free format text: IKS 50928, 950908

PFA Name/firm changed

Owner name: GLAXO GROUP LIMITED, 6-12 CLARGES STREET, LONDON W

SPCG Supplementary protection certificate granted

Free format text: IKS 50928/910327, 950908, EXPIRES:20060212

SPCF Supplementary protection certificate filed

Free format text: IKS 50928/910327, 950908

SPCG Supplementary protection certificate granted

Free format text: IKS 50928/910327, 950908, EXPIRES:20060212

PL Patent ceased
SPCL Supplementary protection certificate deletion

Spc suppl protection certif: C644615/01