ES8207194A1 - Un procedimiento para preparar carbotiatos de androstano - Google Patents

Un procedimiento para preparar carbotiatos de androstano

Info

Publication number
ES8207194A1
ES8207194A1 ES499394A ES499394A ES8207194A1 ES 8207194 A1 ES8207194 A1 ES 8207194A1 ES 499394 A ES499394 A ES 499394A ES 499394 A ES499394 A ES 499394A ES 8207194 A1 ES8207194 A1 ES 8207194A1
Authority
ES
Spain
Prior art keywords
group
alpha
compounds
hydrogen
androstanecarbothioates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES499394A
Other languages
English (en)
Other versions
ES499394A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES8207194A1 publication Critical patent/ES8207194A1/es
Publication of ES499394A0 publication Critical patent/ES499394A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN PROCEDIMIENTO PARA PREPARAR CARBOTIOATOS DE ANDROSTANO. CONSISTE EN SOMERTER A REACCION, DE ESTERIFICACION UN COMPUESTO DE FORMULA GENERAL (I), QUE CONTIENE UN GRUPO ACIDO 17/A/HIDROXILO LIBRE, ESTANDO PROTEGIDOS LOS OTROS GRUPOS REACTIVOS PRESENTES Y SIENDO ELIMINADOS DESPUES DE LA ESTERIFICACION ALGUNO/S DE TALES GRUPOS PROTECTORES PRESENTES PARA OBTENER EL COMPUESTO (I). LA ESTERIFICACION PUEDE TENER LUGAR POR REACCION CON UN ANHIDRIDO O CLORURO DE ACIDO.
ES499394A 1980-02-15 1981-02-13 Un procedimiento para preparar carbotiatos de androstano Granted ES499394A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8005174 1980-02-15
GB8013339 1980-04-23

Publications (2)

Publication Number Publication Date
ES8207194A1 true ES8207194A1 (es) 1982-09-01
ES499394A0 ES499394A0 (es) 1982-09-01

Family

ID=26274505

Family Applications (5)

Application Number Title Priority Date Filing Date
ES499394A Granted ES499394A0 (es) 1980-02-15 1981-02-13 Un procedimiento para preparar carbotiatos de androstano
ES509539A Expired ES8305379A1 (es) 1980-02-15 1982-02-12 Procedimiento para preparar carbotioatos de andorstano.
ES518161A Expired ES8402317A1 (es) 1980-02-15 1982-12-14 Procedimiento para preparar carbotioatos de androstano.
ES524985A Granted ES524985A0 (es) 1980-02-15 1983-08-16 Un procedimiento para preparar carbotioatos de androsteno
ES532055A Granted ES532055A0 (es) 1980-02-15 1984-04-30 Procedimiento para preparar carbotioatos de androstano

Family Applications After (4)

Application Number Title Priority Date Filing Date
ES509539A Expired ES8305379A1 (es) 1980-02-15 1982-02-12 Procedimiento para preparar carbotioatos de andorstano.
ES518161A Expired ES8402317A1 (es) 1980-02-15 1982-12-14 Procedimiento para preparar carbotioatos de androstano.
ES524985A Granted ES524985A0 (es) 1980-02-15 1983-08-16 Un procedimiento para preparar carbotioatos de androsteno
ES532055A Granted ES532055A0 (es) 1980-02-15 1984-04-30 Procedimiento para preparar carbotioatos de androstano

Country Status (23)

Country Link
KR (1) KR850000969B1 (es)
AT (1) AT395427B (es)
AU (1) AU544517B2 (es)
BG (1) BG60700B2 (es)
CH (2) CH651307A5 (es)
CZ (1) CZ281275B6 (es)
DE (2) DE3153379C2 (es)
DK (1) DK147022C (es)
ES (5) ES499394A0 (es)
FI (1) FI70904C (es)
FR (2) FR2477156A1 (es)
HK (1) HK58385A (es)
IE (1) IE51394B1 (es)
IT (1) IT1170717B (es)
KE (1) KE3526A (es)
MX (1) MX9202717A (es)
MY (1) MY8500757A (es)
NL (2) NL191792C (es)
NZ (1) NZ196260A (es)
PT (1) PT72502B (es)
SE (1) SE452468B (es)
SG (1) SG36885G (es)
SK (1) SK278140B6 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA817929B (en) * 1980-12-22 1982-10-27 Upjohn Co 5alpha-and 5beta-androstane-17beta-carboxylates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1436549A (en) * 1972-06-15 1976-05-19 Glaxo Lab Ltd 17beta-mercaptocarbonyl-3alpha-hydroxy-steroids and their esters
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
GB1514476A (en) * 1974-08-30 1978-06-14 Glaxo Lab Ltd Alkyl and haloalkyl androst-4-ene and androsta-1,4-diene-17beta-carboxylates
US4188385A (en) * 1978-04-05 1980-02-12 Syntex (U.S.A.) Inc. Thioetianic acid derivatives
GB1580517A (en) * 1978-04-06 1980-12-03 Fowler I Crutches

Also Published As

Publication number Publication date
IE810282L (en) 1981-08-15
PT72502B (en) 1982-02-05
SK403491A3 (en) 1996-02-07
IE51394B1 (en) 1986-12-24
IT8147792A0 (it) 1981-02-13
FR2477156A1 (fr) 1981-09-04
ES8502447A1 (es) 1985-01-01
ATA67481A (de) 1992-05-15
HK58385A (en) 1985-08-16
MY8500757A (en) 1985-12-31
MX9202717A (es) 1992-06-30
ES518161A0 (es) 1984-01-16
NZ196260A (en) 1983-11-30
KE3526A (en) 1985-06-07
ES524985A0 (es) 1985-01-01
FI810444L (fi) 1981-08-16
NL8100707A (nl) 1981-09-16
NL960029I2 (nl) 1997-04-01
NL191792B (nl) 1996-04-01
FI70904B (fi) 1986-07-18
CZ281275B6 (cs) 1996-08-14
CH651307A5 (de) 1985-09-13
ES509539A0 (es) 1983-04-01
AU544517B2 (en) 1985-06-06
AT395427B (de) 1992-12-28
ES8600936A1 (es) 1985-10-16
BG60700B2 (bg) 1995-12-29
ES532055A0 (es) 1985-10-16
DK147022C (da) 1984-08-27
DK147022B (da) 1984-03-19
DE3105307C2 (es) 1988-09-29
DE3153379C2 (es) 1992-11-19
KR850000969B1 (ko) 1985-07-02
PT72502A (en) 1981-03-01
IT1170717B (it) 1987-06-03
FR2477156B1 (es) 1984-11-16
SE8101010L (sv) 1981-08-16
NL191792C (nl) 1996-08-02
ES8402317A1 (es) 1984-01-16
SK278140B6 (en) 1996-02-07
DE3105307A1 (de) 1981-12-10
ES499394A0 (es) 1982-09-01
FR2485542A1 (fr) 1981-12-31
NL960029I1 (nl) 1997-02-03
KR830005262A (ko) 1983-08-03
ES8305379A1 (es) 1983-04-01
FR2485542B1 (es) 1983-06-10
SG36885G (en) 1985-11-15
CZ403491A3 (en) 1994-03-16
FI70904C (fi) 1986-10-27
DK62381A (da) 1981-08-16
SE452468B (sv) 1987-11-30
CH644615A5 (de) 1984-08-15
AU6729881A (en) 1981-08-20

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