GB1494533A - 3,15(di-lower alkyl)prostadienoic acid derivatives - Google Patents
3,15(di-lower alkyl)prostadienoic acid derivativesInfo
- Publication number
- GB1494533A GB1494533A GB45944/75A GB4594475A GB1494533A GB 1494533 A GB1494533 A GB 1494533A GB 45944/75 A GB45944/75 A GB 45944/75A GB 4594475 A GB4594475 A GB 4594475A GB 1494533 A GB1494533 A GB 1494533A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid derivatives
- alkyl
- lower alkyl
- dialkylprostadienoic
- esterified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 title abstract 4
- POKRQUNDSGAZIA-OALUTQOASA-N 7-[(1r,2s)-2-octylcyclopentyl]hepta-2,4-dienoic acid Chemical class CCCCCCCC[C@H]1CCC[C@@H]1CCC=CC=CC(O)=O POKRQUNDSGAZIA-OALUTQOASA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1494533 3,15 - Dialkylprostadienoic acid derivatives YAMANOUCHI PHARMACEUTICAL CO Ltd 5 Nov 1975 45944/75 Heading C2C [Also in Division C3] The invention comprises 3,15-dialkylprostadienoic acid derivatives of the formula wherein one of A and B is wherein OR<SP>3</SP> is a free, esterified or etherified hydroxy group, and the other one of A and B is C 2 O ; R<SP>1</SP> is H or C 1-4 alkyl ; R<SP>2</SP> is C 1-4 alkyl, and one of R<SP>4</SP> and R<SP>5</SP> is a free, esterified or etherified hydroxy group and the other one of R<SP>4</SP> and R<SP>5</SP> is C 1-4 alkyl and the pharmacologically acceptable salts thereof when R<SP>1</SP> is hydrogen and their preparation by oxidizing compounds of the formula wherein one of M and N is and the other is and if desired, removing any protecting groups present. Pharmaceutical compositions, in the form of tablets, capsules or syrups, contain the above prostaglandins with pharmaceutical carriers. The compounds possess anti-ulcer activity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB45944/75A GB1494533A (en) | 1975-11-05 | 1975-11-05 | 3,15(di-lower alkyl)prostadienoic acid derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB45944/75A GB1494533A (en) | 1975-11-05 | 1975-11-05 | 3,15(di-lower alkyl)prostadienoic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1494533A true GB1494533A (en) | 1977-12-07 |
Family
ID=10439194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB45944/75A Expired GB1494533A (en) | 1975-11-05 | 1975-11-05 | 3,15(di-lower alkyl)prostadienoic acid derivatives |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1494533A (en) |
-
1975
- 1975-11-05 GB GB45944/75A patent/GB1494533A/en not_active Expired
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |