JPS5620597A - Novel physiologically active substance - Google Patents
Novel physiologically active substanceInfo
- Publication number
- JPS5620597A JPS5620597A JP9778279A JP9778279A JPS5620597A JP S5620597 A JPS5620597 A JP S5620597A JP 9778279 A JP9778279 A JP 9778279A JP 9778279 A JP9778279 A JP 9778279A JP S5620597 A JPS5620597 A JP S5620597A
- Authority
- JP
- Japan
- Prior art keywords
- extract
- hexane
- soluble
- silica gel
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
NEW MATERIAL:An extract EK of a plant belonging to the genus Eucalyptus, which has an anti-inflammatory action, will not be steam-distilled, gives an Rf value of 0.4 in thin layer chromatography (on a silica gel plate) when developed by a mixed solvent of n-hexane with ethyl acetate at a volume ratio of 20:1, and a compound EA which is separated and purified from the extract EK and has the following properties: 1) colorless needlelike crystals having a melting point of 169W171°C (recrystallized from EtOH). 2) Molecular formula C28H38O5. 3) [α]D28=+224 ±10° (C=1, in CHCl3). 4) Positive to the FeCl3 reaction etc., and negative to the Dragendorff test. 5) Readily soluble in n-hexane etc., soluble in methanol, DMF, etc., and slightly soluble in water etc.
USE: An anti-inflammatory agent for mammals with low toxicity.
PROCESS: A plant of the genus Eucalyptus is macerated and extracted with a solvent, e.g. n-hexane, at 10W30°C for 6hrW1 week, and the extract is subjected to column chromatography with silica gel to give the extract EK, which is further chromatographed to isolate the compound EA.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9778279A JPS5620597A (en) | 1979-07-30 | 1979-07-30 | Novel physiologically active substance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9778279A JPS5620597A (en) | 1979-07-30 | 1979-07-30 | Novel physiologically active substance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5620597A true JPS5620597A (en) | 1981-02-26 |
Family
ID=14201389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9778279A Pending JPS5620597A (en) | 1979-07-30 | 1979-07-30 | Novel physiologically active substance |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5620597A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008074420A1 (en) * | 2006-12-19 | 2008-06-26 | Intermed Discovery Gmbh | Plants extracts for use in brain modulation |
| CN103755619A (en) * | 2014-01-09 | 2014-04-30 | 嘉兴学院 | Extraction and separation method of prodigiosin |
| US10518164B1 (en) | 2018-09-28 | 2019-12-31 | Spark R&D Ip Holdings, Llc | Systems and methods of fastening splitboard skis |
-
1979
- 1979-07-30 JP JP9778279A patent/JPS5620597A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008074420A1 (en) * | 2006-12-19 | 2008-06-26 | Intermed Discovery Gmbh | Plants extracts for use in brain modulation |
| EP1939166A1 (en) * | 2006-12-19 | 2008-07-02 | InterMed Discovery GmbH | Plants extracts for use in brain modulation |
| JP2010513344A (en) * | 2006-12-19 | 2010-04-30 | インターメッド ディスカヴァリー ゲゼルシャフト ミット ベシュレンクテル ハフツング | Plant extract for use in brain activity change |
| CN103755619A (en) * | 2014-01-09 | 2014-04-30 | 嘉兴学院 | Extraction and separation method of prodigiosin |
| US10518164B1 (en) | 2018-09-28 | 2019-12-31 | Spark R&D Ip Holdings, Llc | Systems and methods of fastening splitboard skis |
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