CH639422A5 - Process for the preparation of novel compounds C-076 - Google Patents

Process for the preparation of novel compounds C-076 Download PDF

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Publication number
CH639422A5
CH639422A5 CH477177A CH477177A CH639422A5 CH 639422 A5 CH639422 A5 CH 639422A5 CH 477177 A CH477177 A CH 477177A CH 477177 A CH477177 A CH 477177A CH 639422 A5 CH639422 A5 CH 639422A5
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CH
Switzerland
Prior art keywords
compounds
hydroxy
dashed line
formula
fractions
Prior art date
Application number
CH477177A
Other languages
German (de)
English (en)
Inventor
Georg Albers-Schonberg
Richard William Burg
Thomas William Miller
Robert Eugene Ormond
Hyman Wallick
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24722350&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CH639422(A5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of CH639422A5 publication Critical patent/CH639422A5/de

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C12P19/623Avermectin; Milbemycin; Ivermectin; C-076
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
CH477177A 1976-04-19 1977-04-18 Process for the preparation of novel compounds C-076 CH639422A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67832876A 1976-04-19 1976-04-19

Publications (1)

Publication Number Publication Date
CH639422A5 true CH639422A5 (en) 1983-11-15

Family

ID=24722350

Family Applications (1)

Application Number Title Priority Date Filing Date
CH477177A CH639422A5 (en) 1976-04-19 1977-04-18 Process for the preparation of novel compounds C-076

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US (1) US4310519A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS52151197A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
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AT (1) AT357503B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
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BG (1) BG35900A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1098063A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH639422A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS207397B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
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IL (1) IL51854A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
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MY (1) MY8200087A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
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ZM (1) ZM3677A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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US4160084A (en) * 1977-10-11 1979-07-03 Merck & Co., Inc. Method for the separation of antibiotic macrolides

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DK146514B (da) 1983-10-24
PT66445A (en) 1977-05-01
YU100177A (en) 1983-02-28
AU513641B2 (en) 1980-12-11
BE853702A (fr) 1977-10-18
SE434277B (sv) 1984-07-16
ES457932A1 (es) 1978-06-01
NL950005I1 (nl) 1995-06-16
NL950005I2 (nl) 1997-02-03
DE2717040C2 (de) 1986-09-18
FI57781C (fi) 1980-10-10
NL971001I2 (nl) 1997-08-01
DK146514C (da) 1984-04-09
BG35900A3 (bg) 1984-07-16
DD137727A5 (de) 1979-09-19
GB1573955A (en) 1980-08-28
HK38481A (en) 1981-08-07
NO771211L (no) 1977-10-20
ZM3677A1 (en) 1978-08-21
NL971001I1 (nl) 1997-06-02
DK149077A (da) 1977-10-20
FR2348970A1 (fr) 1977-11-18
NL188859B (nl) 1992-05-18
NL188859C (nl) 1992-10-16
CY1114A (en) 1981-12-04
ATA266277A (de) 1979-12-15
ZA772345B (en) 1978-12-27
AT357503B (de) 1980-07-10
DE2717040A1 (de) 1977-11-10
IL51854A0 (en) 1977-06-30
GT197746150A (es) 1978-10-10
US4310519A (en) 1982-01-12
FR2348970B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-04-25
IE44822B1 (en) 1982-04-07
HU179041B (en) 1982-08-28
IL51854A (en) 1980-03-31
CS207397B2 (en) 1981-07-31
SU716524A3 (ru) 1980-02-15
SE7703592L (sv) 1977-10-20
YU40814B (en) 1986-06-30
AR215000A1 (es) 1979-08-31
FI57781B (fi) 1980-06-30
GR63128B (en) 1979-09-17
FI771124A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-10-20
JPH0217558B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1990-04-20
KE3141A (en) 1981-07-24
MY8200087A (en) 1982-12-31
IE44822L (en) 1977-10-19
AU2422077A (en) 1978-10-19
NO148856B (no) 1983-09-19
LU77152A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-11-17
PT66445B (en) 1979-03-09
OA05638A (fr) 1981-04-30
IT1106424B (it) 1985-11-11
PL108004B1 (pl) 1980-03-31
NO148856C (no) 1983-12-28
NZ183847A (en) 1980-05-08
CA1098063A (en) 1981-03-24
RO71785A (ro) 1982-10-26
JPS52151197A (en) 1977-12-15
NL7703810A (nl) 1977-10-21

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