CH617452A5 - - Google Patents
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- Publication number
- CH617452A5 CH617452A5 CH1431374A CH1431374A CH617452A5 CH 617452 A5 CH617452 A5 CH 617452A5 CH 1431374 A CH1431374 A CH 1431374A CH 1431374 A CH1431374 A CH 1431374A CH 617452 A5 CH617452 A5 CH 617452A5
- Authority
- CH
- Switzerland
- Prior art keywords
- pyrimidine
- cyano
- straight
- carbon atoms
- mixture according
- Prior art date
Links
- 125000004432 carbon atom Chemical group C* 0.000 claims description 69
- 150000001875 compounds Chemical class 0.000 claims description 62
- 239000000203 mixture Substances 0.000 claims description 57
- -1 n-pentyloxy, n-hexyloxy Chemical group 0.000 claims description 53
- 125000000217 alkyl group Chemical group 0.000 claims description 41
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 claims description 40
- 125000003545 alkoxy group Chemical group 0.000 claims description 24
- 125000004423 acyloxy group Chemical group 0.000 claims description 20
- HHPCNRKYVYWYAU-UHFFFAOYSA-N 4-cyano-4'-pentylbiphenyl Chemical group C1=CC(CCCCC)=CC=C1C1=CC=C(C#N)C=C1 HHPCNRKYVYWYAU-UHFFFAOYSA-N 0.000 claims description 18
- 125000005910 alkyl carbonate group Chemical group 0.000 claims description 16
- RGONNDWSVOCREF-UHFFFAOYSA-N 4-(5-pentylpyrimidin-2-yl)benzonitrile Chemical compound N1=CC(CCCCC)=CN=C1C1=CC=C(C#N)C=C1 RGONNDWSVOCREF-UHFFFAOYSA-N 0.000 claims description 13
- YYXBAYZPDQVLAE-UHFFFAOYSA-N 2-(4-hexylphenyl)pyrimidine-5-carbonitrile Chemical compound C1=CC(CCCCCC)=CC=C1C1=NC=C(C#N)C=N1 YYXBAYZPDQVLAE-UHFFFAOYSA-N 0.000 claims description 11
- VSNGFYYRBATOTN-UHFFFAOYSA-N 4-(5-heptylpyrimidin-2-yl)benzonitrile Chemical compound N1=CC(CCCCCCC)=CN=C1C1=CC=C(C#N)C=C1 VSNGFYYRBATOTN-UHFFFAOYSA-N 0.000 claims description 11
- 239000000126 substance Substances 0.000 claims description 11
- 125000004093 cyano group Chemical group *C#N 0.000 claims description 10
- VWJMXUYCJCQLLY-UHFFFAOYSA-N 2-(4-pentylphenyl)pyrimidine-5-carbonitrile Chemical compound C1=CC(CCCCC)=CC=C1C1=NC=C(C#N)C=N1 VWJMXUYCJCQLLY-UHFFFAOYSA-N 0.000 claims description 9
- JFDZBHWFFUWGJE-UHFFFAOYSA-N benzonitrile Chemical compound N#CC1=CC=CC=C1 JFDZBHWFFUWGJE-UHFFFAOYSA-N 0.000 claims description 9
- 150000002148 esters Chemical class 0.000 claims description 9
- LBFLIDCXWNVNLB-UHFFFAOYSA-N 2-(4-butoxyphenyl)pyrimidine-5-carbonitrile Chemical compound C1=CC(OCCCC)=CC=C1C1=NC=C(C#N)C=N1 LBFLIDCXWNVNLB-UHFFFAOYSA-N 0.000 claims description 7
- BSKDQEJRUNEAQO-UHFFFAOYSA-N 2-(4-butylphenyl)pyrimidine-5-carbonitrile Chemical compound C1=CC(CCCC)=CC=C1C1=NC=C(C#N)C=N1 BSKDQEJRUNEAQO-UHFFFAOYSA-N 0.000 claims description 7
- 238000002360 preparation method Methods 0.000 claims description 7
- ZGOWXOZNUNZPAV-UHFFFAOYSA-N 4-(4-heptylphenyl)benzonitrile Chemical group C1=CC(CCCCCCC)=CC=C1C1=CC=C(C#N)C=C1 ZGOWXOZNUNZPAV-UHFFFAOYSA-N 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 6
- 125000001424 substituent group Chemical group 0.000 claims description 6
- OIRIIWRPWWSCPD-UHFFFAOYSA-N 2-(4-propylphenyl)pyrimidine-5-carbonitrile Chemical compound C1=CC(CCC)=CC=C1C1=NC=C(C#N)C=N1 OIRIIWRPWWSCPD-UHFFFAOYSA-N 0.000 claims description 5
- MAYOJSWIHDBLSY-UHFFFAOYSA-N 4-(5-hexylpyrimidin-2-yl)benzonitrile Chemical compound N1=CC(CCCCCC)=CN=C1C1=CC=C(C#N)C=C1 MAYOJSWIHDBLSY-UHFFFAOYSA-N 0.000 claims description 5
- 230000008569 process Effects 0.000 claims description 5
- MGEQCYFPPOWIEZ-UHFFFAOYSA-N 2-(4-pentoxyphenyl)pyrimidine-5-carbonitrile Chemical compound C1=CC(OCCCCC)=CC=C1C1=NC=C(C#N)C=N1 MGEQCYFPPOWIEZ-UHFFFAOYSA-N 0.000 claims description 4
- 239000002253 acid Substances 0.000 claims description 4
- 239000000460 chlorine Substances 0.000 claims description 4
- 229910052740 iodine Inorganic materials 0.000 claims description 4
- 125000003136 n-heptyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 4
- 125000001280 n-hexyl group Chemical group C(CCCCC)* 0.000 claims description 4
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 4
- CNHDIAIOKMXOLK-UHFFFAOYSA-N toluquinol Chemical compound CC1=CC(O)=CC=C1O CNHDIAIOKMXOLK-UHFFFAOYSA-N 0.000 claims description 4
- RYSIQVHNOVJIFG-UHFFFAOYSA-N 1-heptyl-4-phenylcyclohexa-2,4-diene-1-carbonitrile Chemical group C1=CC(CCCCCCC)(C#N)CC=C1C1=CC=CC=C1 RYSIQVHNOVJIFG-UHFFFAOYSA-N 0.000 claims description 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims description 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 3
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims description 3
- 229910052794 bromium Inorganic materials 0.000 claims description 3
- 229910052801 chlorine Inorganic materials 0.000 claims description 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 3
- JPBFKTCKZLMJED-UHFFFAOYSA-N 4-(4-heptoxyphenyl)benzonitrile Chemical group C1=CC(OCCCCCCC)=CC=C1C1=CC=C(C#N)C=C1 JPBFKTCKZLMJED-UHFFFAOYSA-N 0.000 claims description 2
- WNPUCDQWHSMXIN-UHFFFAOYSA-N 4-[(4-propylphenyl)methylideneamino]benzonitrile Chemical compound C1=CC(CCC)=CC=C1C=NC1=CC=C(C#N)C=C1 WNPUCDQWHSMXIN-UHFFFAOYSA-N 0.000 claims description 2
- NWVVVBRKAWDGAB-UHFFFAOYSA-N hydroquinone methyl ether Natural products COC1=CC=C(O)C=C1 NWVVVBRKAWDGAB-UHFFFAOYSA-N 0.000 claims description 2
- ZQLDNJKHLQOJGE-UHFFFAOYSA-N 4-octylbenzoic acid Chemical compound CCCCCCCCC1=CC=C(C(O)=O)C=C1 ZQLDNJKHLQOJGE-UHFFFAOYSA-N 0.000 claims 2
- WBYWAXJHAXSJNI-VOTSOKGWSA-M .beta-Phenylacrylic acid Natural products [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 claims 1
- AVTDOVBURKPMSX-UHFFFAOYSA-N 3-heptyl-4-phenylbenzonitrile Chemical group CCCCCCCC1=CC(C#N)=CC=C1C1=CC=CC=C1 AVTDOVBURKPMSX-UHFFFAOYSA-N 0.000 claims 1
- GPGGNNIMKOVSAG-UHFFFAOYSA-N 4-(4-octoxyphenyl)benzonitrile Chemical group C1=CC(OCCCCCCCC)=CC=C1C1=CC=C(C#N)C=C1 GPGGNNIMKOVSAG-UHFFFAOYSA-N 0.000 claims 1
- GYTQATZRVCZAKR-UHFFFAOYSA-N 4-[(4-butylphenyl)methylideneamino]benzonitrile Chemical compound C1=CC(CCCC)=CC=C1C=NC1=CC=C(C#N)C=C1 GYTQATZRVCZAKR-UHFFFAOYSA-N 0.000 claims 1
- BPMBNLJJRKCCRT-UHFFFAOYSA-N 4-phenylbenzonitrile Chemical group C1=CC(C#N)=CC=C1C1=CC=CC=C1 BPMBNLJJRKCCRT-UHFFFAOYSA-N 0.000 claims 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims 1
- 230000001419 dependent effect Effects 0.000 claims 1
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 80
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 69
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 36
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 description 35
- 239000000243 solution Substances 0.000 description 34
- 238000006243 chemical reaction Methods 0.000 description 33
- 239000007858 starting material Substances 0.000 description 33
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 30
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 30
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 30
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 28
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 24
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 24
- 230000008018 melting Effects 0.000 description 22
- 238000002844 melting Methods 0.000 description 22
- 239000011541 reaction mixture Substances 0.000 description 21
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 19
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 description 19
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 17
- QDRKDTQENPPHOJ-UHFFFAOYSA-N sodium ethoxide Chemical compound [Na+].CC[O-] QDRKDTQENPPHOJ-UHFFFAOYSA-N 0.000 description 17
- 238000003756 stirring Methods 0.000 description 17
- 239000013078 crystal Substances 0.000 description 16
- 239000000155 melt Substances 0.000 description 16
- 238000010992 reflux Methods 0.000 description 14
- 239000004990 Smectic liquid crystal Substances 0.000 description 13
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 description 12
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 12
- 125000004429 atom Chemical group 0.000 description 12
- 230000007717 exclusion Effects 0.000 description 12
- SCVFZCLFOSHCOH-UHFFFAOYSA-M potassium acetate Chemical compound [K+].CC([O-])=O SCVFZCLFOSHCOH-UHFFFAOYSA-M 0.000 description 12
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 10
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 10
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 10
- 229910021529 ammonia Inorganic materials 0.000 description 9
- 230000007935 neutral effect Effects 0.000 description 8
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 7
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 7
- 239000007788 liquid Substances 0.000 description 7
- 229910052938 sodium sulfate Inorganic materials 0.000 description 7
- 235000011152 sodium sulphate Nutrition 0.000 description 7
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 6
- 238000001816 cooling Methods 0.000 description 6
- 238000004821 distillation Methods 0.000 description 6
- 239000001257 hydrogen Substances 0.000 description 6
- 229910052739 hydrogen Inorganic materials 0.000 description 6
- UKVIEHSSVKSQBA-UHFFFAOYSA-N methane;palladium Chemical compound C.[Pd] UKVIEHSSVKSQBA-UHFFFAOYSA-N 0.000 description 6
- 235000011056 potassium acetate Nutrition 0.000 description 6
- 229920006395 saturated elastomer Polymers 0.000 description 6
- 125000004801 4-cyanophenyl group Chemical group [H]C1=C([H])C(C#N)=C([H])C([H])=C1* 0.000 description 5
- 230000002378 acidificating effect Effects 0.000 description 5
- LTMHNWPUDSTBKD-UHFFFAOYSA-N diethyl 2-(ethoxymethylidene)propanedioate Chemical compound CCOC=C(C(=O)OCC)C(=O)OCC LTMHNWPUDSTBKD-UHFFFAOYSA-N 0.000 description 5
- 229910052757 nitrogen Inorganic materials 0.000 description 5
- 239000000741 silica gel Substances 0.000 description 5
- 229910002027 silica gel Inorganic materials 0.000 description 5
- WSLDOOZREJYCGB-UHFFFAOYSA-N 1,2-Dichloroethane Chemical compound ClCCCl WSLDOOZREJYCGB-UHFFFAOYSA-N 0.000 description 4
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 4
- 102100022404 E3 ubiquitin-protein ligase Midline-1 Human genes 0.000 description 4
- 101710102210 E3 ubiquitin-protein ligase Midline-1 Proteins 0.000 description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 4
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 4
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 4
- 239000006227 byproduct Substances 0.000 description 4
- 239000003990 capacitor Substances 0.000 description 4
- 239000012071 phase Substances 0.000 description 4
- 239000002244 precipitate Substances 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- AOJFQRQNPXYVLM-UHFFFAOYSA-N pyridin-1-ium;chloride Chemical compound [Cl-].C1=CC=[NH+]C=C1 AOJFQRQNPXYVLM-UHFFFAOYSA-N 0.000 description 4
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 4
- 229910052708 sodium Inorganic materials 0.000 description 4
- 239000011734 sodium Substances 0.000 description 4
- 239000000725 suspension Substances 0.000 description 4
- HIKJBZUXMYBAIL-UHFFFAOYSA-N 3-(4-hexylphenyl)prop-2-enoic acid Chemical compound CCCCCCC1=CC=C(C=CC(O)=O)C=C1 HIKJBZUXMYBAIL-UHFFFAOYSA-N 0.000 description 3
- AWNRWPLYMABILG-UHFFFAOYSA-N 4-(4-heptylpyrimidin-2-yl)benzoic acid Chemical compound CCCCCCCC1=CC=NC(C=2C=CC(=CC=2)C(O)=O)=N1 AWNRWPLYMABILG-UHFFFAOYSA-N 0.000 description 3
- ZJEFILYXLZSVJZ-UHFFFAOYSA-N 4-chloropyrimidine-5-carboxylic acid Chemical compound OC(=O)C1=CN=CN=C1Cl ZJEFILYXLZSVJZ-UHFFFAOYSA-N 0.000 description 3
- CVNOWLNNPYYEOH-UHFFFAOYSA-N 4-cyanophenol Chemical compound OC1=CC=C(C#N)C=C1 CVNOWLNNPYYEOH-UHFFFAOYSA-N 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 3
- WQDUMFSSJAZKTM-UHFFFAOYSA-N Sodium methoxide Chemical compound [Na+].[O-]C WQDUMFSSJAZKTM-UHFFFAOYSA-N 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 230000018044 dehydration Effects 0.000 description 3
- 238000006297 dehydration reaction Methods 0.000 description 3
- 238000001704 evaporation Methods 0.000 description 3
- 230000008020 evaporation Effects 0.000 description 3
- 229910052736 halogen Inorganic materials 0.000 description 3
- 150000002367 halogens Chemical class 0.000 description 3
- 239000004973 liquid crystal related substance Substances 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- IIVUJUOJERNGQX-UHFFFAOYSA-N pyrimidine-5-carboxylic acid Chemical compound OC(=O)C1=CN=CN=C1 IIVUJUOJERNGQX-UHFFFAOYSA-N 0.000 description 3
- 159000000000 sodium salts Chemical class 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- WCJUJMPIFZMWOZ-UHFFFAOYSA-N 1-pentyl-4-phenylcyclohexa-2,4-diene-1-carbonitrile Chemical group C1=CC(CCCCC)(C#N)CC=C1C1=CC=CC=C1 WCJUJMPIFZMWOZ-UHFFFAOYSA-N 0.000 description 2
- YOHHRYUEXZWDRY-UHFFFAOYSA-N 2-(4-heptylphenyl)pyrimidine-5-carbonitrile Chemical compound C1=CC(CCCCCCC)=CC=C1C1=NC=C(C#N)C=N1 YOHHRYUEXZWDRY-UHFFFAOYSA-N 0.000 description 2
- AOGLHEUFDNEXOC-UHFFFAOYSA-N 2-(4-heptylphenyl)pyrimidine-5-carboxamide Chemical compound C1=CC(CCCCCCC)=CC=C1C1=NC=C(C(N)=O)C=N1 AOGLHEUFDNEXOC-UHFFFAOYSA-N 0.000 description 2
- WDVUTSPKHBUTKG-UHFFFAOYSA-N 2-(4-heptylphenyl)pyrimidine-5-carboxylic acid Chemical compound C1=CC(CCCCCCC)=CC=C1C1=NC=C(C(O)=O)C=N1 WDVUTSPKHBUTKG-UHFFFAOYSA-N 0.000 description 2
- GNPMRDPPLWHZOG-UHFFFAOYSA-N 2-(4-hexylphenyl)pyrimidine-5-carboxamide Chemical compound C1=CC(CCCCCC)=CC=C1C1=NC=C(C(N)=O)C=N1 GNPMRDPPLWHZOG-UHFFFAOYSA-N 0.000 description 2
- XMMZSDRQCFGODE-UHFFFAOYSA-N 2-(4-pentylphenyl)pyrimidine-5-carboxamide Chemical compound C1=CC(CCCCC)=CC=C1C1=NC=C(C(N)=O)C=N1 XMMZSDRQCFGODE-UHFFFAOYSA-N 0.000 description 2
- IMGZUSNTHIVXDL-UHFFFAOYSA-N 2-(4-pentylphenyl)pyrimidine-5-carboxylic acid Chemical compound C1=CC(CCCCC)=CC=C1C1=NC=C(C(O)=O)C=N1 IMGZUSNTHIVXDL-UHFFFAOYSA-N 0.000 description 2
- VLWDPGULDDHWMP-UHFFFAOYSA-N 2-(4-propoxyphenyl)pyrimidine-5-carbonitrile Chemical compound C1=CC(OCCC)=CC=C1C1=NC=C(C#N)C=N1 VLWDPGULDDHWMP-UHFFFAOYSA-N 0.000 description 2
- QPFDPJJNUKGHBB-UHFFFAOYSA-N 2-(ethoxymethylidene)nonanal Chemical compound CCCCCCCC(C=O)=COCC QPFDPJJNUKGHBB-UHFFFAOYSA-N 0.000 description 2
- IPQKEGWWCUGHJQ-UHFFFAOYSA-N 4-(4-butylpyrimidin-2-yl)benzamide Chemical compound CCCCC1=CC=NC(C=2C=CC(=CC=2)C(N)=O)=N1 IPQKEGWWCUGHJQ-UHFFFAOYSA-N 0.000 description 2
- ZRMIETZFPZGBEB-UHFFFAOYSA-N 4-(4-hydroxyphenyl)benzonitrile Chemical group C1=CC(O)=CC=C1C1=CC=C(C#N)C=C1 ZRMIETZFPZGBEB-UHFFFAOYSA-N 0.000 description 2
- LGZVXDCVOZLFAW-UHFFFAOYSA-N 4-(5-butylpyrimidin-2-yl)benzonitrile Chemical compound N1=CC(CCCC)=CN=C1C1=CC=C(C#N)C=C1 LGZVXDCVOZLFAW-UHFFFAOYSA-N 0.000 description 2
- SEBTZFGCLRTNBV-UHFFFAOYSA-N 4-(5-octylpyrimidin-2-yl)benzonitrile Chemical compound N1=CC(CCCCCCCC)=CN=C1C1=CC=C(C#N)C=C1 SEBTZFGCLRTNBV-UHFFFAOYSA-N 0.000 description 2
- PRLHVXKHKAROHU-UHFFFAOYSA-N 4-butylbenzenecarboximidamide;hydrochloride Chemical compound Cl.CCCCC1=CC=C(C(N)=N)C=C1 PRLHVXKHKAROHU-UHFFFAOYSA-N 0.000 description 2
- IYIAWOSYBLPUNL-UHFFFAOYSA-N 4-carbamimidoylbenzamide;hydrochloride Chemical compound Cl.NC(=N)C1=CC=C(C(N)=O)C=C1 IYIAWOSYBLPUNL-UHFFFAOYSA-N 0.000 description 2
- WZWIQYMTQZCSKI-UHFFFAOYSA-N 4-cyanobenzaldehyde Chemical compound O=CC1=CC=C(C#N)C=C1 WZWIQYMTQZCSKI-UHFFFAOYSA-N 0.000 description 2
- FJKROLUGYXJWQN-UHFFFAOYSA-N 4-hydroxybenzoic acid Chemical compound OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 2
- HGINCPLSRVDWNT-UHFFFAOYSA-N Acrolein Chemical compound C=CC=O HGINCPLSRVDWNT-UHFFFAOYSA-N 0.000 description 2
- 239000005711 Benzoic acid Substances 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 2
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- 150000008282 halocarbons Chemical class 0.000 description 1
- 210000002837 heart atrium Anatomy 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 239000005457 ice water Substances 0.000 description 1
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Natural products C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 1
- 125000006606 n-butoxy group Chemical group 0.000 description 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 125000001298 n-hexoxy group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])O* 0.000 description 1
- 125000003506 n-propoxy group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])O* 0.000 description 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- 125000005499 phosphonyl group Chemical group 0.000 description 1
- DLYUQMMRRRQYAE-UHFFFAOYSA-N phosphorus pentoxide Inorganic materials O1P(O2)(=O)OP3(=O)OP1(=O)OP2(=O)O3 DLYUQMMRRRQYAE-UHFFFAOYSA-N 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- QDXGKRWDQCEABB-UHFFFAOYSA-N pyrimidine-5-carboxamide Chemical compound NC(=O)C1=CN=CN=C1 QDXGKRWDQCEABB-UHFFFAOYSA-N 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000004043 responsiveness Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 239000010414 supernatant solution Substances 0.000 description 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- WBYWAXJHAXSJNI-VOTSOKGWSA-N trans-cinnamic acid Chemical class OC(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-N 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000010626 work up procedure Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K19/00—Liquid crystal materials
- C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
- C09K19/42—Mixtures of liquid crystal compounds covered by two or more of the preceding groups C09K19/06 - C09K19/40
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/515—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/02—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen
- C07C47/12—Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing more than one —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
- C07C51/38—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by decarboxylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K19/00—Liquid crystal materials
- C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
- C09K19/06—Non-steroidal liquid crystal compounds
- C09K19/34—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
- C09K19/3441—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom
- C09K19/345—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom the heterocyclic ring being a six-membered aromatic ring containing two nitrogen atoms
- C09K19/3458—Uncondensed pyrimidines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Liquid Crystal Substances (AREA)
- Liquid Crystal (AREA)
Priority Applications (24)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1431374A CH617452A5 (it) | 1974-10-25 | 1974-10-25 | |
ZA00756410A ZA756410B (en) | 1974-10-25 | 1975-10-09 | Phenyl pyrimidines |
AU85670/75A AU476921B2 (en) | 1974-10-25 | 1975-10-13 | Phenyl pyrimidines |
IT28443/75A IT1043486B (it) | 1974-10-25 | 1975-10-20 | Fenil pirimidine |
US05/624,354 US3997536A (en) | 1974-10-25 | 1975-10-21 | Phenyl-pyrimidines |
FR7532424A FR2309543A1 (fr) | 1974-10-25 | 1975-10-23 | Nouvelles phenylpyrimidines, leur procede de preparation et leur application electro-optique |
DD189021A DD124731A5 (it) | 1974-10-25 | 1975-10-23 | |
DD7500198028A DD128698A5 (de) | 1974-10-25 | 1975-10-23 | Nematisches gemisch |
SE7511902A SE417962B (sv) | 1974-10-25 | 1975-10-23 | Fenylpyrimidiner for elektro-optiska endamal |
JP50127576A JPS5180870A (en) | 1974-10-25 | 1975-10-24 | Fueniruupirimijinno seizohoho |
BE161221A BE834837A (fr) | 1974-10-25 | 1975-10-24 | Phenylpyrimidines |
AT814575A AT349475B (de) | 1974-10-25 | 1975-10-24 | Verfahren zur herstellung von neuen phenylpyrimidinen |
GB4382275A GB1473990A (en) | 1974-10-25 | 1975-10-24 | Phenyl-pyrimidines |
ES442044A ES442044A1 (es) | 1974-10-25 | 1975-10-24 | Un procedimiento para la preparacion de fenil-pirimidinas. |
DK479675A DK479675A (da) | 1974-10-25 | 1975-10-24 | Phenylpyrimidiner |
CA238,291A CA1042889A (en) | 1974-10-25 | 1975-10-24 | Phenyl pyrimidines |
DE2547737A DE2547737C2 (de) | 1974-10-25 | 1975-10-24 | Phenylpyrimidine |
NLAANVRAGE7512497,A NL176172C (nl) | 1974-10-25 | 1975-10-24 | Werkwijze voor het bereiden van mengsels met nematische eigenschappen en het bereiden van daarvoor geschikte pyrimidine-verbindingen. |
US05/721,257 US4066570A (en) | 1974-10-25 | 1976-09-08 | Phenyl-pyrimidines |
DK382677A DK382677A (da) | 1974-10-25 | 1977-08-29 | Flydende krystallinske blandinger |
HK72/78A HK7278A (en) | 1974-10-25 | 1978-02-10 | Phenyl-pyrimidines |
JP1997778A JPS53101385A (en) | 1974-10-25 | 1978-02-24 | Method of producing phenyllpyrimidine |
JP1997678A JPS53114788A (en) | 1974-10-25 | 1978-02-24 | Nematic liquid crystal matter mixture |
AT556178A AT362429B (de) | 1974-10-25 | 1978-07-31 | Nematisches gemisch fuer elektrooptische zwecke |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1431374A CH617452A5 (it) | 1974-10-25 | 1974-10-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH617452A5 true CH617452A5 (it) | 1980-05-30 |
Family
ID=4399774
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1431374A CH617452A5 (it) | 1974-10-25 | 1974-10-25 |
Country Status (18)
Country | Link |
---|---|
US (1) | US3997536A (it) |
JP (3) | JPS5180870A (it) |
AT (1) | AT349475B (it) |
AU (1) | AU476921B2 (it) |
BE (1) | BE834837A (it) |
CA (1) | CA1042889A (it) |
CH (1) | CH617452A5 (it) |
DD (2) | DD124731A5 (it) |
DE (1) | DE2547737C2 (it) |
DK (2) | DK479675A (it) |
ES (1) | ES442044A1 (it) |
FR (1) | FR2309543A1 (it) |
GB (1) | GB1473990A (it) |
HK (1) | HK7278A (it) |
IT (1) | IT1043486B (it) |
NL (1) | NL176172C (it) |
SE (1) | SE417962B (it) |
ZA (1) | ZA756410B (it) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4062798A (en) * | 1975-09-19 | 1977-12-13 | Hoffmann-La Roche Inc. | Phenylpyrimidine derivatives |
NL7701750A (nl) * | 1976-02-26 | 1977-08-30 | Hoffmann La Roche | Mengsels van vloeibare kristallen. |
US4052397A (en) * | 1976-11-22 | 1977-10-04 | Ciba-Geigy Corporation | Process for the production of 2-alkyl or 2-cycloalkyl-4-methyl-6-hydroxypyrimidines |
US4052396A (en) * | 1976-11-22 | 1977-10-04 | Ciba-Geigy Corporation | Process for the production of 2-alkyl or 2-cycloalkyl-4-methyl-6-hydroxypyrimidines |
JPS5411887A (en) * | 1977-06-29 | 1979-01-29 | Sharp Corp | Liquid crystal composition |
DD138558A1 (de) * | 1977-12-08 | 1979-11-07 | Frank Kuschel | Nematische fluessig-kristalline gemische |
JPS5483694A (en) * | 1977-12-16 | 1979-07-03 | Hitachi Ltd | Nematic liquid crystal body for display device |
JPS5941983B2 (ja) * | 1978-02-17 | 1984-10-11 | 大日本インキ化学工業株式会社 | トランス(エカトリアル↓−エカトリアル)1,4↓−ジ置換シクロヘキサン誘導体 |
US4309539A (en) * | 1978-03-13 | 1982-01-05 | Hoffmann-La Roche Inc. | Pyrimidine derivatives |
US4163848A (en) * | 1978-08-08 | 1979-08-07 | Ciba-Geigy Corporation | Process for the production of 2-alkyl- or cycloalkyl-4-methyl-6-hydroxypyrimidines |
JPS5534206A (en) * | 1978-08-30 | 1980-03-10 | Hitachi Ltd | Nematic liquid crystal for display unit |
DE2944905A1 (de) * | 1978-12-13 | 1980-10-23 | Werk Fernsehelektronik Veb | Kristallin-fluessige substituierte 1,3-dioxane und diese enthaltende gemische |
CA1120478A (en) * | 1979-02-05 | 1982-03-23 | Arthur Boller | Cyclohexyl pyrimidines |
DE3014912A1 (de) * | 1979-05-15 | 1980-11-27 | Werk Fernsehelektronik Veb | Nematische fluessigkristalline 5-cyan- 2- eckige klammer auf 4-acyloxyphenyl eckige klammer zu -pyrimidine und diese enthaltende gemische |
DE3063497D1 (en) * | 1979-08-20 | 1983-07-07 | Werk Fernsehelektronik Veb | Nematic crystalline-liquid 5-alkyl-2-(4-acyloxyphenyl)-pyrimidines for opto-electronic arrangements and process for their preparation |
CH652400A5 (en) * | 1979-11-14 | 1985-11-15 | Hoffmann La Roche | Phenyldioxanes, and liquid-crystalline mixtures containing them |
US4364838A (en) * | 1979-11-14 | 1982-12-21 | Hoffmann-La Roche Inc. | Liquid crystal mixtures |
DE2951099A1 (de) * | 1979-12-19 | 1981-06-25 | Merck Patent Gmbh, 6100 Darmstadt | Tetrahydrochinazoline, verfahren zu ihrer herstellung, diese enthaltende fluessigkristalline dielektrika und elektrooptisches anzeigeelement |
JPS56113768A (en) * | 1980-02-15 | 1981-09-07 | Seiko Epson Corp | Compound |
JPS56116774A (en) * | 1980-02-19 | 1981-09-12 | Seiko Epson Corp | Nematic liquid crystal composition |
US4335011A (en) * | 1980-03-28 | 1982-06-15 | Timex Corporation | Cyclohexyl-dioxane liquid crystalline compounds |
US4335012A (en) * | 1980-04-03 | 1982-06-15 | Timex Corporation | 5-Substituted-2-(4-cyanophenyl)-1,3-dioxanes |
DE3023989A1 (de) * | 1980-06-26 | 1982-01-21 | Merck Patent Gmbh, 6100 Darmstadt | Fluessigkristallines dielektrikum |
CH645102A5 (de) * | 1980-10-14 | 1984-09-14 | Hoffmann La Roche | Disubstituierte pyrimidine. |
JPS5790082A (en) * | 1980-11-26 | 1982-06-04 | Seiko Epson Corp | Liquid crystal composition |
JPS57117583A (en) * | 1981-01-12 | 1982-07-22 | Seiko Epson Corp | Liquid crystal composition |
US4452718A (en) * | 1981-07-31 | 1984-06-05 | Hoffmann-La Roche Inc. | Pyridazines |
CH651025A5 (de) * | 1982-05-14 | 1985-08-30 | Hoffmann La Roche | Pyridazine und ihre verwendung als komponenten fluessigkristalliner gemische. |
US4528114A (en) * | 1981-12-18 | 1985-07-09 | Hoffmann-La Roche Inc. | Acetylenes |
US5227484A (en) * | 1982-01-14 | 1993-07-13 | Merck Patent Gmbh | Anisotropic compounds having nematic phase and liquid crystal mixtures |
JPS58128356A (ja) * | 1982-01-28 | 1983-07-30 | Ube Ind Ltd | 2−アルコキシメチレン−3,3−ジアルコキシブロパンニトリル類 |
GB2120242A (en) * | 1982-04-30 | 1983-11-30 | Erba Farmitalia | Ergoline derivatives |
JPS5939876A (ja) * | 1982-08-26 | 1984-03-05 | Chisso Corp | ピリミジン誘導体 |
GB2133004B (en) * | 1982-11-04 | 1986-06-11 | Ici Plc | Process for the extraction of metal values and novel metal extractants |
DE3465192D1 (en) * | 1983-03-16 | 1987-09-10 | Hoffmann La Roche | Liquid crystal components having an alkenyl chain |
US4581155A (en) * | 1983-03-31 | 1986-04-08 | Chisso Corporation | Halogenopyrimidine derivatives |
DE3315295A1 (de) * | 1983-04-27 | 1984-10-31 | Merck Patent Gmbh, 6100 Darmstadt | Fluorhaltige pyrimidinderivate |
EP0136480B1 (en) * | 1983-08-22 | 1990-01-17 | Chisso Corporation | 2,3-dicyano-5-substituted pyrazines and liquid crystal composition containing them |
JPS60146877A (ja) * | 1984-01-11 | 1985-08-02 | Chisso Corp | 2―置換―6―(5―置換―2―ピリミジニル)ナフタリン |
US4609485A (en) * | 1984-02-17 | 1986-09-02 | Chisso Corporation | Bipyrimidinyl derivatives |
DE3411571A1 (de) * | 1984-03-29 | 1985-10-10 | Merck Patent Gmbh, 6100 Darmstadt | Pyrimidine |
EP0169327B1 (de) * | 1984-05-25 | 1988-01-13 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Phenylisothiocyanate |
EP0191860B1 (en) * | 1984-06-07 | 1990-04-18 | Seiko Instruments Inc. | Liquid crystal compound |
JPS61215372A (ja) * | 1985-03-20 | 1986-09-25 | Teikoku Chem Ind Corp Ltd | 液晶化合物 |
JPS61152659A (ja) * | 1984-12-27 | 1986-07-11 | Chisso Corp | 1,4−ジピリミジニルベンゼン誘導体 |
DE3500909A1 (de) * | 1985-01-12 | 1986-07-17 | Merck Patent Gmbh, 6100 Darmstadt | Pyrimidine |
JPS61180775A (ja) * | 1985-01-22 | 1986-08-13 | メルク・パテント・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | ジヒドロアジン液晶化合物 |
JPS61197563A (ja) * | 1985-02-27 | 1986-09-01 | Chisso Corp | トリフルオロメチルフエニル基をもつピリミジン誘導体 |
JPS61233689A (ja) * | 1985-03-22 | 1986-10-17 | メルク・パテント・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | 複素環式ホウ素化合物 |
EP0195974B1 (de) * | 1985-03-26 | 1989-11-29 | F. Hoffmann-La Roche Ag | Alkenylsubstituierte Phenylisothiocyanate und Benzonitrile |
US4980082A (en) * | 1986-09-02 | 1990-12-25 | Seiko Instruments Inc. | Ferroelectric SmC liquid crystal composition which comprises pyrimidinylphenyl ester compounds |
CA1341098C (en) * | 1988-08-25 | 2000-09-12 | Kazuhiko Sakaguchi | Liquid crystal composition and use thereof |
DE3928267A1 (de) * | 1989-08-26 | 1991-02-28 | Merck Patent Gmbh | 5-oxy-2-phenylpyrimidine und fluessigkristallines medium |
JPH07278545A (ja) * | 1994-04-14 | 1995-10-24 | Chisso Corp | ネマテック液晶組成物 |
CN103965111A (zh) * | 2014-05-05 | 2014-08-06 | 淮海工学院 | 一种含有水杨醛席夫碱的双子季铵盐及其制备方法 |
WO2016007638A1 (en) * | 2014-07-08 | 2016-01-14 | Dow Agrosciences Llc | Process for the preparation of 4-alkoxy-3-hydroxypicolinic acids |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH593495A5 (it) * | 1971-12-22 | 1977-12-15 | Werk Fernsehelektronik Veb | |
DD107563A1 (it) * | 1973-09-27 | 1974-08-05 |
-
1974
- 1974-10-25 CH CH1431374A patent/CH617452A5/de not_active IP Right Cessation
-
1975
- 1975-10-09 ZA ZA00756410A patent/ZA756410B/xx unknown
- 1975-10-13 AU AU85670/75A patent/AU476921B2/en not_active Expired
- 1975-10-20 IT IT28443/75A patent/IT1043486B/it active
- 1975-10-21 US US05/624,354 patent/US3997536A/en not_active Expired - Lifetime
- 1975-10-23 DD DD189021A patent/DD124731A5/xx unknown
- 1975-10-23 SE SE7511902A patent/SE417962B/xx unknown
- 1975-10-23 FR FR7532424A patent/FR2309543A1/fr active Granted
- 1975-10-23 DD DD7500198028A patent/DD128698A5/xx unknown
- 1975-10-24 ES ES442044A patent/ES442044A1/es not_active Expired
- 1975-10-24 BE BE161221A patent/BE834837A/xx unknown
- 1975-10-24 AT AT814575A patent/AT349475B/de not_active IP Right Cessation
- 1975-10-24 JP JP50127576A patent/JPS5180870A/ja active Granted
- 1975-10-24 DK DK479675A patent/DK479675A/da not_active Application Discontinuation
- 1975-10-24 NL NLAANVRAGE7512497,A patent/NL176172C/xx not_active IP Right Cessation
- 1975-10-24 CA CA238,291A patent/CA1042889A/en not_active Expired
- 1975-10-24 DE DE2547737A patent/DE2547737C2/de not_active Expired
- 1975-10-24 GB GB4382275A patent/GB1473990A/en not_active Expired
-
1977
- 1977-08-29 DK DK382677A patent/DK382677A/da not_active Application Discontinuation
-
1978
- 1978-02-10 HK HK72/78A patent/HK7278A/xx unknown
- 1978-02-24 JP JP1997678A patent/JPS53114788A/ja active Pending
- 1978-02-24 JP JP1997778A patent/JPS53101385A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU8567075A (en) | 1976-10-07 |
NL176172B (nl) | 1984-10-01 |
FR2309543A1 (fr) | 1976-11-26 |
HK7278A (en) | 1978-02-17 |
AT349475B (de) | 1979-04-10 |
DK382677A (da) | 1977-08-29 |
FR2309543B1 (it) | 1978-04-07 |
DE2547737A1 (de) | 1976-04-29 |
ES442044A1 (es) | 1977-06-16 |
JPS53114788A (en) | 1978-10-06 |
JPS5180870A (en) | 1976-07-15 |
ATA814575A (de) | 1978-09-15 |
DD124731A5 (it) | 1977-03-09 |
DK479675A (da) | 1976-04-26 |
IT1043486B (it) | 1980-02-20 |
US3997536A (en) | 1976-12-14 |
GB1473990A (en) | 1977-05-18 |
SE417962B (sv) | 1981-04-27 |
JPS556631B2 (it) | 1980-02-18 |
AU476921B2 (en) | 1976-10-07 |
NL176172C (nl) | 1985-03-01 |
JPS53101385A (en) | 1978-09-04 |
SE7511902L (sv) | 1976-04-26 |
ZA756410B (en) | 1976-09-29 |
DE2547737C2 (de) | 1982-09-16 |
NL7512497A (nl) | 1976-04-27 |
DD128698A5 (de) | 1977-12-07 |
CA1042889A (en) | 1978-11-21 |
BE834837A (fr) | 1976-04-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUE | Assignment |
Owner name: F. HOFFMANN-LA ROCHE AG |
|
PL | Patent ceased |