CH584209A5 - 3-amino-2-hydroxypropoxy substd. diazines and pyridines - with beta-adrenergic blocking or stimulating activity - Google Patents

3-amino-2-hydroxypropoxy substd. diazines and pyridines - with beta-adrenergic blocking or stimulating activity

Info

Publication number
CH584209A5
CH584209A5 CH244473A CH244473A CH584209A5 CH 584209 A5 CH584209 A5 CH 584209A5 CH 244473 A CH244473 A CH 244473A CH 244473 A CH244473 A CH 244473A CH 584209 A5 CH584209 A5 CH 584209A5
Authority
CH
Switzerland
Prior art keywords
lower alkyl
carbon atoms
alkyl
alkoxy
compounds
Prior art date
Application number
CH244473A
Other languages
German (de)
English (en)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to CH244473A priority Critical patent/CH584209A5/de
Priority to AR257058A priority patent/AR206801A1/es
Priority to AR257055A priority patent/AR207133A1/es
Priority to AR257054A priority patent/AR208397A1/es
Priority to FI193/74A priority patent/FI60391C/fi
Priority to SE7401114A priority patent/SE420834B/xx
Priority to IE255/74A priority patent/IE38839B1/xx
Priority to CA192,292A priority patent/CA1027131A/en
Priority to IL44202A priority patent/IL44202A/xx
Priority to NO740486A priority patent/NO139682C/no
Priority to GB651874A priority patent/GB1465946A/en
Priority to DE19742406930 priority patent/DE2406930A1/de
Priority to DK80774A priority patent/DK143501C/da
Priority to ES423362A priority patent/ES423362A1/es
Priority to LU69415A priority patent/LU69415A1/xx
Priority to DD176616A priority patent/DD110041A5/xx
Priority to FR7405391A priority patent/FR2218101B1/fr
Priority to AU65726/74A priority patent/AU493478B2/en
Priority to SU741995950A priority patent/SU659089A3/ru
Priority to YU43674A priority patent/YU37150B/xx
Priority to MX700274U priority patent/MX5291E/es
Priority to PL1974184285A priority patent/PL100172B1/pl
Priority to PL1974184283A priority patent/PL100171B1/pl
Priority to PL1974189132A priority patent/PL98967B1/pl
Priority to PL1974184284A priority patent/PL100314B1/pl
Priority to PL1974168938A priority patent/PL94250B1/pl
Priority to ZA00741070A priority patent/ZA741070B/xx
Priority to PL1974189131A priority patent/PL98964B1/pl
Priority to MC1097A priority patent/MC1013A1/xx
Priority to BE141130A priority patent/BE811274A/xx
Priority to HU74CI1447A priority patent/HU173821B/hu
Priority to AT133074A priority patent/AT335455B/de
Priority to PL1974203732A priority patent/PL101376B1/pl
Priority to AR252438A priority patent/AR214612A1/es
Priority to CS741252A priority patent/CS203970B2/cs
Priority to NL7402332A priority patent/NL7402332A/xx
Priority to AR257057A priority patent/AR203878A1/es
Priority to SU7502137664A priority patent/SU577978A3/ru
Priority to SU752141281A priority patent/SU593657A3/ru
Priority to AT948775A priority patent/AT336618B/de
Priority to AT948875A priority patent/AT336018B/de
Priority to AT948675A priority patent/AT336628B/de
Priority to AT948475A priority patent/AT336617B/de
Priority to AT948975A priority patent/AT338787B/de
Priority to AR264155A priority patent/AR208043A1/es
Priority to ES446083A priority patent/ES446083A1/es
Priority to ES76446081A priority patent/ES446081A1/es
Priority to ES76446082A priority patent/ES446082A1/es
Priority to US05/757,529 priority patent/US4115575A/en
Publication of CH584209A5 publication Critical patent/CH584209A5/de
Priority to US05/883,434 priority patent/US4195090A/en
Priority to YU156780A priority patent/YU156780A/xx
Priority to YU156880A priority patent/YU156880A/xx
Priority to YU156980A priority patent/YU156980A/xx
Priority to DK364180A priority patent/DK364180A/da
Priority to US06/266,546 priority patent/US4410530A/en
Priority to JP57132301A priority patent/JPS5823666A/ja
Priority to JP57132300A priority patent/JPS603391B2/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
CH244473A 1973-02-20 1973-02-20 3-amino-2-hydroxypropoxy substd. diazines and pyridines - with beta-adrenergic blocking or stimulating activity CH584209A5 (en)

Priority Applications (57)

Application Number Priority Date Filing Date Title
CH244473A CH584209A5 (en) 1973-02-20 1973-02-20 3-amino-2-hydroxypropoxy substd. diazines and pyridines - with beta-adrenergic blocking or stimulating activity
AR257058A AR206801A1 (es) 1973-02-20 1974-01-01 Procedimiento para la elaboracion de derivados del 1-pirid loxi-2-hidroxi-3-amino-propano
AR257055A AR207133A1 (es) 1973-02-20 1974-01-01 Procedimiento para la elaboracion de derivados de 1-piridiloxi 1-pirimidiniloxi y 1-piraziniloxi-2-hidroxi-3-amino-propano
AR257054A AR208397A1 (es) 1973-02-20 1974-01-01 Procedimiento para la elaboracion de compuestos de 1-piridiloxi-2-hidroxi-3-amino-propano1-piraziniloxi-2-hidroxi-3-amino-propano y 1-pirimidiniloxi-2-hidroxi-3-amino-propan
FI193/74A FI60391C (fi) 1973-02-20 1974-01-23 Analogifoerfarande foer framstaellning av beta-reseptor-aktiva 1-heterocyklyloxi-3-amino-2-propanolfoereningar
SE7401114A SE420834B (sv) 1973-02-20 1974-01-29 Analogiforfarande for framstellning av beta-receptoraktiva derivat av 2-hydroxi-3-aminopropan
IE255/74A IE38839B1 (en) 1973-02-20 1974-02-11 Pyridazinyl,pyrimidinyl,pyrazinyl and pyridyl compounds and processes for their manufacture
CA192,292A CA1027131A (en) 1973-02-20 1974-02-12 Heterocyclic compounds and processes for their manufacture
IL44202A IL44202A (en) 1973-02-20 1974-02-13 (3-amino-2-hydroxy-propoxy)-diazines and -pyridine derivatives,their manufacture and pharmaceutical compositions containing them
NO740486A NO139682C (no) 1973-02-20 1974-02-13 Analogifremgangsmaate til fremstilling av beta-reseptor-aktive forbindelser
GB651874A GB1465946A (en) 1973-02-20 1974-02-13 Pyridazinyl,pyrimidinyl,pyrazinyl and pyridyl compounds and processes for their manufacture
DE19742406930 DE2406930A1 (de) 1973-02-20 1974-02-14 Neue heterocyclische verbindungen und verfahren zu ihrer herstellung
DK80774A DK143501C (da) 1973-02-20 1974-02-15 Analogifremgangsmaade til fremstilling af beta-receptorblokerende derivater af 2-hydroxy-3-aminopropan eller terapeutisk anvendelige salte deraf
ES423362A ES423362A1 (es) 1973-02-20 1974-02-18 Procedimiento para la obtencion de derivados de 2-hidroxi-3aminopropano de actividad beta-receptora.
LU69415A LU69415A1 (xx) 1973-02-20 1974-02-18
DD176616A DD110041A5 (xx) 1973-02-20 1974-02-18
FR7405391A FR2218101B1 (xx) 1973-02-20 1974-02-18
AU65726/74A AU493478B2 (en) 1974-02-18 New heterocyclic compounds and processes for their manufacture
SU741995950A SU659089A3 (ru) 1973-02-20 1974-02-18 Способ получени производных 2-окси-3-аминопропана или их -окисей или солей
YU43674A YU37150B (en) 1973-02-20 1974-02-19 Process for preparing new pyridyloxy-, pyrazinyloxy-, pyrimidinyloxy- and pyridazinyloxy-2-hydroxy-3-aminopropanes
MX700274U MX5291E (es) 1973-02-20 1974-02-19 Procedimiento para obtener derivados heterociclicos de 2-hidroxi-3-aminopropano
PL1974184285A PL100172B1 (pl) 1973-02-20 1974-02-19 Sposob wytwarzania nowych pochodnych 2-hydroksy-3-aminopropanu
PL1974184283A PL100171B1 (pl) 1973-02-20 1974-02-19 Sposob wytwarzania nowych pochodnych 1-pirazynyloksy-2-hydroksy-3-aminopropanu
PL1974189132A PL98967B1 (pl) 1973-02-20 1974-02-19 Sposob wytwarzania nowych pochodnych 1-pirymidynyloksy-2-hydroksy-3-aminopropanu
PL1974184284A PL100314B1 (pl) 1973-02-20 1974-02-19 Sposob wytwarzania nowych pochodnych 1-pirydyloksy-2-hydroksy-3-aminopropanu
PL1974168938A PL94250B1 (xx) 1973-02-20 1974-02-19
ZA00741070A ZA741070B (en) 1973-02-20 1974-02-19 New heterocyclic compounds and processes for their manufacture
PL1974189131A PL98964B1 (pl) 1973-02-20 1974-02-19 Sposob wytwarzania nowych pochodnych 1-pirazynyloksy-2-hydroksy-3-aminopropanu
MC1097A MC1013A1 (fr) 1973-02-20 1974-02-19 Nouveaux composés hétérocycliques et leurs procédés de préparation
BE141130A BE811274A (fr) 1973-02-20 1974-02-19 Nouveaux composes heterocycliques et leurs procedes de preparation
HU74CI1447A HU173821B (hu) 1973-02-20 1974-02-19 Sposob poluchenija novykh proizvodnykh 2 - gidroksi - 3 - amino - propana
AT133074A AT335455B (de) 1973-02-20 1974-02-19 Verfahren zur herstellung von neuen heterocyclischen verbindungen
PL1974203732A PL101376B1 (pl) 1973-02-20 1974-02-19 Sposob wytwarzania nowych pochodnych 2-hydroksy-3-aminopropanu
AR252438A AR214612A1 (es) 1973-02-20 1974-02-20 Procedimiento para preparar nuevos derivados de 1-piridiloxi-,1-piraziniloxi-,1-pirodaziniloxi o 1-pirimidiniloxi-2-hidroxi-3-amino-propano
CS741252A CS203970B2 (en) 1973-02-20 1974-02-20 Method of producing novel heterocyclyl-oxy-hydroxy-amino-propanes
NL7402332A NL7402332A (en) 1973-02-20 1974-02-20 3-amino-2-hydroxypropoxy substd. diazines and pyridines
AR257057A AR203878A1 (es) 1973-02-20 1974-12-23 Procedimiento para la elaboracion de compuestos del 1-piraziniloxi 2-hidroxi-3-aminopropano
SU7502137664A SU577978A3 (ru) 1973-02-20 1975-05-27 Способ получени производных 1пиразинил-окси-2-окси-3-аминопропана или их солей
SU752141281A SU593657A3 (ru) 1973-02-20 1975-06-06 Способ получени производных 1-пиридилокси-2-окси-3-аминопропана или их солей
AT948775A AT336618B (de) 1973-02-20 1975-12-15 Verfahren zur herstellung von neuen heterocyclischen verbindungen
AT948875A AT336018B (de) 1973-02-20 1975-12-15 Verfahren zur herstellung von neuen heterocyclischen verbindungen
AT948675A AT336628B (de) 1973-02-20 1975-12-15 Verfahren zur herstellung von beta-rezeptoren-aktiven derivaten des 2-hydroxy-3-aminopropan deren n-oxiden, optisch aktiven formen und isomeren und deren saureadditionssalzen
AT948475A AT336617B (de) 1973-02-20 1975-12-15 Verfahren zur herstellung von neuen heterocyclischen verbindungen
AT948975A AT338787B (de) 1973-02-20 1975-12-15 Verfahren zur herstellung von neuen heterocyclischen verbindungen
AR264155A AR208043A1 (es) 1973-02-20 1976-01-01 Procedimiento para la elaboracion de derivados de 1-piridiloxi 1-pirimidiniloxi y 1-piraziniloxi-2-hidroxi-3-amino propano
ES446083A ES446083A1 (es) 1973-02-20 1976-03-16 Procedimiento para la obtencion de derivados del 2-hidroxi-3-aminopropano de actividad beta-receptora.
ES76446081A ES446081A1 (es) 1973-02-20 1976-03-16 Procedimiento para la obtencion de derivados del 2-hidroxi-3-aminopropano de actividad beta-receptora.
ES76446082A ES446082A1 (es) 1973-02-20 1976-03-16 Procedimiento para la obtencion de derivados de 1-pirazini- loxi-2-hidroxi-3-aminopropano.
US05/757,529 US4115575A (en) 1973-02-20 1977-01-07 2-(3-Amino-2-hydroxy-propoxy)-pyrazines
US05/883,434 US4195090A (en) 1973-02-20 1978-03-03 2-(3-Amino-2-hydroxy-propoxy)pyridine derivatives and pharmaceutical compositions therewith
YU156780A YU156780A (en) 1973-02-20 1980-06-12 Process for preparing new heterocyclyloxy-2-hydroxy-3-aminopropanes
YU156880A YU156880A (en) 1973-02-20 1980-06-12 Process for preparing new heterocyclyloxy-2-hydroxy-3-aminopropanes
YU156980A YU156980A (en) 1973-02-20 1980-06-12 Process for preparing new 1-pyridyloxy-2-hydroxy-3-aminopropane derivatives
DK364180A DK364180A (da) 1973-02-20 1980-08-25 Analogifremgangsmaade til fremstilling af betareceptorstimulerende derivater af 2-hydroxy-3-amino-propan
US06/266,546 US4410530A (en) 1973-02-20 1981-05-22 2-(3-Amino-2-hydroxy-propoxy)-mono-and diazines
JP57132301A JPS5823666A (ja) 1973-02-20 1982-07-30 新規ピリミジン化合物の製法
JP57132300A JPS603391B2 (ja) 1973-02-20 1982-07-30 新規ピリミジン化合物の製法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH244473A CH584209A5 (en) 1973-02-20 1973-02-20 3-amino-2-hydroxypropoxy substd. diazines and pyridines - with beta-adrenergic blocking or stimulating activity

Publications (1)

Publication Number Publication Date
CH584209A5 true CH584209A5 (en) 1977-01-31

Family

ID=4233957

Family Applications (1)

Application Number Title Priority Date Filing Date
CH244473A CH584209A5 (en) 1973-02-20 1973-02-20 3-amino-2-hydroxypropoxy substd. diazines and pyridines - with beta-adrenergic blocking or stimulating activity

Country Status (9)

Country Link
JP (2) JPS5823666A (xx)
CH (1) CH584209A5 (xx)
FI (1) FI60391C (xx)
HU (1) HU173821B (xx)
MC (1) MC1013A1 (xx)
NO (1) NO139682C (xx)
PL (7) PL98964B1 (xx)
SU (3) SU659089A3 (xx)
ZA (1) ZA741070B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4517188A (en) * 1983-05-09 1985-05-14 Mead Johnson & Company 1-Pyrimidinyloxy-3-hetaryl-alkylamino-2-propanols

Also Published As

Publication number Publication date
PL98964B1 (pl) 1978-06-30
SU577978A3 (ru) 1977-10-25
PL100171B1 (pl) 1978-09-30
FI60391C (fi) 1982-01-11
PL98967B1 (pl) 1978-06-30
FI60391B (fi) 1981-09-30
MC1013A1 (fr) 1974-10-18
PL94250B1 (xx) 1977-07-30
PL100314B1 (pl) 1978-09-30
JPS5823675A (ja) 1983-02-12
SU659089A3 (ru) 1979-04-25
JPS603391B2 (ja) 1985-01-28
NO139682C (no) 1979-04-25
NO139682B (no) 1979-01-15
PL100172B1 (pl) 1978-09-30
SU593657A3 (ru) 1978-02-15
HU173821B (hu) 1979-08-28
PL101376B1 (pl) 1978-12-30
JPS5823666A (ja) 1983-02-12
ZA741070B (en) 1975-01-29
NO740486L (no) 1974-08-21

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