FI60391C - Analogifoerfarande foer framstaellning av beta-reseptor-aktiva 1-heterocyklyloxi-3-amino-2-propanolfoereningar - Google Patents

Analogifoerfarande foer framstaellning av beta-reseptor-aktiva 1-heterocyklyloxi-3-amino-2-propanolfoereningar Download PDF

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Publication number
FI60391C
FI60391C FI193/74A FI19374A FI60391C FI 60391 C FI60391 C FI 60391C FI 193/74 A FI193/74 A FI 193/74A FI 19374 A FI19374 A FI 19374A FI 60391 C FI60391 C FI 60391C
Authority
FI
Finland
Prior art keywords
hydroxy
formula
isopropylamino
het
lower alkyl
Prior art date
Application number
FI193/74A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI60391B (fi
Inventor
Joerg Frei
Knut A Jaeggi
Franz Ostermayer
Herbert Schroeter
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AR257054A priority Critical patent/AR208397A1/es
Priority to AR257058A priority patent/AR206801A1/es
Priority to AR257055A priority patent/AR207133A1/es
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to SE7401114A priority patent/SE420834B/xx
Priority to IE255/74A priority patent/IE38839B1/xx
Priority to CA192,292A priority patent/CA1027131A/en
Priority to IL44202A priority patent/IL44202A/xx
Priority to GB651874A priority patent/GB1465946A/en
Priority to DE19742406930 priority patent/DE2406930A1/de
Priority to DK80774A priority patent/DK143501C/da
Priority to DD176616A priority patent/DD110041A5/xx
Priority to LU69415A priority patent/LU69415A1/xx
Priority to FR7405391A priority patent/FR2218101B1/fr
Priority to BE141130A priority patent/BE811274A/xx
Priority to AT133074A priority patent/AT335455B/de
Priority to AR252438A priority patent/AR214612A1/es
Priority to NL7402332A priority patent/NL7402332A/xx
Priority to CS741252A priority patent/CS203970B2/cs
Priority to AR257057A priority patent/AR203878A1/es
Priority to AT948775A priority patent/AT336618B/de
Priority to AT948975A priority patent/AT338787B/de
Priority to AT948475A priority patent/AT336617B/de
Priority to AT948875A priority patent/AT336018B/de
Priority to AR264155A priority patent/AR208043A1/es
Priority to ES76446081A priority patent/ES446081A1/es
Priority to ES446083A priority patent/ES446083A1/es
Priority to US05/757,529 priority patent/US4115575A/en
Priority to US05/883,434 priority patent/US4195090A/en
Priority to DK364180A priority patent/DK364180A/da
Priority to US06/266,546 priority patent/US4410530A/en
Publication of FI60391B publication Critical patent/FI60391B/fi
Application granted granted Critical
Publication of FI60391C publication Critical patent/FI60391C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI193/74A 1973-02-20 1974-01-23 Analogifoerfarande foer framstaellning av beta-reseptor-aktiva 1-heterocyklyloxi-3-amino-2-propanolfoereningar FI60391C (fi)

Priority Applications (30)

Application Number Priority Date Filing Date Title
AR257054A AR208397A1 (es) 1973-02-20 1974-01-01 Procedimiento para la elaboracion de compuestos de 1-piridiloxi-2-hidroxi-3-amino-propano1-piraziniloxi-2-hidroxi-3-amino-propano y 1-pirimidiniloxi-2-hidroxi-3-amino-propan
AR257058A AR206801A1 (es) 1973-02-20 1974-01-01 Procedimiento para la elaboracion de derivados del 1-pirid loxi-2-hidroxi-3-amino-propano
AR257055A AR207133A1 (es) 1973-02-20 1974-01-01 Procedimiento para la elaboracion de derivados de 1-piridiloxi 1-pirimidiniloxi y 1-piraziniloxi-2-hidroxi-3-amino-propano
SE7401114A SE420834B (sv) 1973-02-20 1974-01-29 Analogiforfarande for framstellning av beta-receptoraktiva derivat av 2-hydroxi-3-aminopropan
IE255/74A IE38839B1 (en) 1973-02-20 1974-02-11 Pyridazinyl,pyrimidinyl,pyrazinyl and pyridyl compounds and processes for their manufacture
CA192,292A CA1027131A (en) 1973-02-20 1974-02-12 Heterocyclic compounds and processes for their manufacture
IL44202A IL44202A (en) 1973-02-20 1974-02-13 (3-amino-2-hydroxy-propoxy)-diazines and -pyridine derivatives,their manufacture and pharmaceutical compositions containing them
GB651874A GB1465946A (en) 1973-02-20 1974-02-13 Pyridazinyl,pyrimidinyl,pyrazinyl and pyridyl compounds and processes for their manufacture
DE19742406930 DE2406930A1 (de) 1973-02-20 1974-02-14 Neue heterocyclische verbindungen und verfahren zu ihrer herstellung
DK80774A DK143501C (da) 1973-02-20 1974-02-15 Analogifremgangsmaade til fremstilling af beta-receptorblokerende derivater af 2-hydroxy-3-aminopropan eller terapeutisk anvendelige salte deraf
LU69415A LU69415A1 (xx) 1973-02-20 1974-02-18
FR7405391A FR2218101B1 (xx) 1973-02-20 1974-02-18
DD176616A DD110041A5 (xx) 1973-02-20 1974-02-18
AT133074A AT335455B (de) 1973-02-20 1974-02-19 Verfahren zur herstellung von neuen heterocyclischen verbindungen
BE141130A BE811274A (fr) 1973-02-20 1974-02-19 Nouveaux composes heterocycliques et leurs procedes de preparation
AR252438A AR214612A1 (es) 1973-02-20 1974-02-20 Procedimiento para preparar nuevos derivados de 1-piridiloxi-,1-piraziniloxi-,1-pirodaziniloxi o 1-pirimidiniloxi-2-hidroxi-3-amino-propano
NL7402332A NL7402332A (en) 1973-02-20 1974-02-20 3-amino-2-hydroxypropoxy substd. diazines and pyridines
CS741252A CS203970B2 (en) 1973-02-20 1974-02-20 Method of producing novel heterocyclyl-oxy-hydroxy-amino-propanes
AR257057A AR203878A1 (es) 1973-02-20 1974-12-23 Procedimiento para la elaboracion de compuestos del 1-piraziniloxi 2-hidroxi-3-aminopropano
AT948475A AT336617B (de) 1973-02-20 1975-12-15 Verfahren zur herstellung von neuen heterocyclischen verbindungen
AT948975A AT338787B (de) 1973-02-20 1975-12-15 Verfahren zur herstellung von neuen heterocyclischen verbindungen
AT948775A AT336618B (de) 1973-02-20 1975-12-15 Verfahren zur herstellung von neuen heterocyclischen verbindungen
AT948875A AT336018B (de) 1973-02-20 1975-12-15 Verfahren zur herstellung von neuen heterocyclischen verbindungen
AR264155A AR208043A1 (es) 1973-02-20 1976-01-01 Procedimiento para la elaboracion de derivados de 1-piridiloxi 1-pirimidiniloxi y 1-piraziniloxi-2-hidroxi-3-amino propano
ES446083A ES446083A1 (es) 1973-02-20 1976-03-16 Procedimiento para la obtencion de derivados del 2-hidroxi-3-aminopropano de actividad beta-receptora.
ES76446081A ES446081A1 (es) 1973-02-20 1976-03-16 Procedimiento para la obtencion de derivados del 2-hidroxi-3-aminopropano de actividad beta-receptora.
US05/757,529 US4115575A (en) 1973-02-20 1977-01-07 2-(3-Amino-2-hydroxy-propoxy)-pyrazines
US05/883,434 US4195090A (en) 1973-02-20 1978-03-03 2-(3-Amino-2-hydroxy-propoxy)pyridine derivatives and pharmaceutical compositions therewith
DK364180A DK364180A (da) 1973-02-20 1980-08-25 Analogifremgangsmaade til fremstilling af betareceptorstimulerende derivater af 2-hydroxy-3-amino-propan
US06/266,546 US4410530A (en) 1973-02-20 1981-05-22 2-(3-Amino-2-hydroxy-propoxy)-mono-and diazines

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH244473A CH584209A5 (en) 1973-02-20 1973-02-20 3-amino-2-hydroxypropoxy substd. diazines and pyridines - with beta-adrenergic blocking or stimulating activity
CH244473 1973-02-20

Publications (2)

Publication Number Publication Date
FI60391B FI60391B (fi) 1981-09-30
FI60391C true FI60391C (fi) 1982-01-11

Family

ID=4233957

Family Applications (1)

Application Number Title Priority Date Filing Date
FI193/74A FI60391C (fi) 1973-02-20 1974-01-23 Analogifoerfarande foer framstaellning av beta-reseptor-aktiva 1-heterocyklyloxi-3-amino-2-propanolfoereningar

Country Status (9)

Country Link
JP (2) JPS5823666A (xx)
CH (1) CH584209A5 (xx)
FI (1) FI60391C (xx)
HU (1) HU173821B (xx)
MC (1) MC1013A1 (xx)
NO (1) NO139682C (xx)
PL (7) PL94250B1 (xx)
SU (3) SU659089A3 (xx)
ZA (1) ZA741070B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4517188A (en) * 1983-05-09 1985-05-14 Mead Johnson & Company 1-Pyrimidinyloxy-3-hetaryl-alkylamino-2-propanols

Also Published As

Publication number Publication date
JPS603391B2 (ja) 1985-01-28
CH584209A5 (en) 1977-01-31
SU659089A3 (ru) 1979-04-25
SU593657A3 (ru) 1978-02-15
SU577978A3 (ru) 1977-10-25
PL98967B1 (pl) 1978-06-30
ZA741070B (en) 1975-01-29
PL98964B1 (pl) 1978-06-30
FI60391B (fi) 1981-09-30
PL100314B1 (pl) 1978-09-30
PL101376B1 (pl) 1978-12-30
JPS5823666A (ja) 1983-02-12
PL94250B1 (xx) 1977-07-30
PL100172B1 (pl) 1978-09-30
NO139682B (no) 1979-01-15
NO740486L (no) 1974-08-21
HU173821B (hu) 1979-08-28
JPS5823675A (ja) 1983-02-12
PL100171B1 (pl) 1978-09-30
MC1013A1 (fr) 1974-10-18
NO139682C (no) 1979-04-25

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