CH472402A - Verfahren zur Herstellung neuer heterocyclischer Derivate - Google Patents

Verfahren zur Herstellung neuer heterocyclischer Derivate

Info

Publication number
CH472402A
CH472402A CH1481668A CH1481668A CH472402A CH 472402 A CH472402 A CH 472402A CH 1481668 A CH1481668 A CH 1481668A CH 1481668 A CH1481668 A CH 1481668A CH 472402 A CH472402 A CH 472402A
Authority
CH
Switzerland
Prior art keywords
heterocyclic derivatives
preparation
radical
carbon atoms
formula
Prior art date
Application number
CH1481668A
Other languages
German (de)
English (en)
Inventor
Howe Ralph
Joseph Mcloughlin Bernard
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Priority claimed from CH1587067A external-priority patent/CH473800A/de
Publication of CH472402A publication Critical patent/CH472402A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82Xanthenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18Ethylenedioxybenzenes, not substituted on the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D321/00Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02Seven-membered rings
    • C07D321/10Seven-membered rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D321/00Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/12Eight-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CH1481668A 1963-07-30 1964-07-20 Verfahren zur Herstellung neuer heterocyclischer Derivate CH472402A (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB30135/63A GB1058822A (en) 1963-07-30 1963-07-30 3-amino-2-hydroxypropoxy heterocyclic derivatives
GB199064 1964-01-16
CH1587067A CH473800A (de) 1963-07-30 1964-07-20 Verfahren zur Herstellung neuer heterocyclischer Derivate
CH949464A CH468372A (de) 1963-07-30 1964-07-20 Verfahren zur Herstellung neuer heterocyclischer Derivate

Publications (1)

Publication Number Publication Date
CH472402A true CH472402A (de) 1969-05-15

Family

ID=26237125

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1481668A CH472402A (de) 1963-07-30 1964-07-20 Verfahren zur Herstellung neuer heterocyclischer Derivate
CH949464A CH468372A (de) 1963-07-30 1964-07-20 Verfahren zur Herstellung neuer heterocyclischer Derivate

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH949464A CH468372A (de) 1963-07-30 1964-07-20 Verfahren zur Herstellung neuer heterocyclischer Derivate

Country Status (10)

Country Link
US (1) US3340266A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE651032A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR6461288D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (2) CH472402A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (2) DK119432B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES302622A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (2) FR1583153A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1058822A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL139234B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (4) SE316488B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003758A1 (de) * 1978-02-09 1979-09-05 Ciba-Geigy Ag Verätherte Hydroxy-benzodiheterocyclen und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3511851A (en) * 1967-06-12 1970-05-12 Du Pont Heterocyclic amino-oxazolines
US3655661A (en) * 1968-05-22 1972-04-11 Frosst & Co Charles E Benzothiadiazole compounds
GB1253709A (en) * 1968-05-22 1971-11-17 Frosst & Co Charles E Thiadiazole derivatives
US3668206A (en) * 1968-10-16 1972-06-06 Venkatachala Lakshmi Narayanan Heterocyclic amine derivatives of 5,8-dihydronaphthyloxy propanols
GB1308191A (en) * 1970-04-06 1973-02-21 Science Union & Cie Thiochroman derivatives and a process for preparing them
US3853923A (en) * 1971-05-13 1974-12-10 Kakenyaku Kako Kk 2-substituted-(2-hydroxy-3-lower alkaminopropoxy)-benzofurans
US3910924A (en) * 1972-04-13 1975-10-07 Otsuka Pharma Co Ltd 3,4-Dihydrocarbostyril derivatives and a process for preparing the same
JPS517672B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1972-04-13 1976-03-10
US3856818A (en) * 1972-07-03 1974-12-24 Squibb & Sons Inc Tricyclic phenoxy aminopropanols
AR207554A1 (es) * 1972-12-02 1976-10-15 Otsuka Pharma Co Ltd Procedimiento para producir derivados de 3-alquil-5-((3,4-dihidro-5-carbostiril)oximetil)-oxazolidinona-(2)
JPS5239035B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1972-12-14 1977-10-03
US4073909A (en) * 1973-10-08 1978-02-14 Sandoz Ltd. Isoquinoline compounds
GB1509527A (en) * 1974-06-05 1978-05-04 Ici Ltd 1-(aryl-or heteroaryl)oxy-3-(substituted-amino)propan-2-ol derivatives processes for their manufacture and pharmaceutical compositions containing them
US3894058A (en) * 1974-05-17 1975-07-08 Hoechst Co American Tetrahydrobenzofuranylphenoxypropylamines
US4070470A (en) * 1974-06-24 1978-01-24 Otsuka Pharmaceutical Co., Ltd. Platelet aggregation inhibiting carbostyrils, their compositions and method of use
GB1472959A (en) * 1974-09-26 1977-05-11 Roche Products Ltd Benzofuran derivatives and a process for the manufacture thereof
FI58329C (fi) * 1974-11-08 1981-01-12 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av i 8-staellning substituerade 5-(3'-alkylamino-2'-hydroxi)propoxi-3,4-dihydrokarbostyrilderivat
AR206061A1 (es) * 1974-11-15 1976-06-23 Knoll Ag Procedimiento para la produccion de nuevas 2-alcanoil (c1-c4)-1, 2, 3, 4-tetrahidro-8-respectivamente 7-, 6- o 5-(2-hidroxi-3-alquil (c3-c4)-aminopropoxi)-isoquinolinas de 2-alcanoil (c1-c4)-1, 2, 3, 4-tetrahidro-8-respectivamente 7- o 5-(2-hidroxi-3-alquil (c3-c4)-aminopropoxi)-6-metoxi-isoquinolinas y de 2-alcanoil (c1-c4)-1, 2, 3, 4-tetrahidro-8-respectivamente 6- o 5-(2-hidroxi-3-alquil (c3-c4)-aminopropoxi)-7-metoxi-isoquinolinas eventualmente metiladas en la posicion 1
BE839967R (fr) * 1975-03-26 1976-09-24 Nouveaux derives de l'isoquinoleine, leur preparation et leur application comme medicaments
DE2611148A1 (de) * 1975-03-26 1976-10-14 Sandoz Ag Organische verbindungen, ihre verwendung und herstellung
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
GB1504424A (en) * 1975-08-09 1978-03-22 Beecham Group Ltd Isoquinoline-derived aminoethers
CA1089866A (en) * 1975-10-20 1980-11-18 Kiyoshi Ito Benzofuran derivatives, preparation thereof and pharmaceutical compositions thereof
US4139537A (en) 1976-06-29 1979-02-13 Cooper Laboratories, Inc. 3-Aryloxy-1-(2- or 4-iminodihydro-1-pyridyl)-2-propanol antiarrhythmic compounds
DE2704794C3 (de) * 1977-02-05 1979-10-11 Basf Ag, 6700 Ludwigshafen Aminopropanolderivate des 4-Hydroxy-l^-benzisothiazols
DE2704793C2 (de) * 1977-02-05 1979-03-08 Basf Ag, 6700 Ludwigshafen 4-Hydroxy-l,2-benzisothiazole
NZ187066A (en) * 1977-05-03 1981-02-11 Hoffmann La Roche 4-(3-substitutedamino-2-hydroxypropoxy)-benzimidazolidin-2-(ones or thiones)
US4235919A (en) * 1977-07-21 1980-11-25 Sandoz Ltd. 1-(Indol-4-yloxy)-3-(2-substituted amino)-2-propanols and pharmaceutical use thereof
DE2801980A1 (de) * 1978-01-18 1979-07-19 Boehringer Mannheim Gmbh 4-hydroxy-2-benzimidazolin-thion- derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
US4202978A (en) * 1978-02-08 1980-05-13 Hoffmann-La Roche Inc. (S)-1-[2-(4-(2-Hydroxy-s-(1-alkylaminopropoxy)phenylalkyl]-4-phenylpiperazines
DE2901336A1 (de) 1979-01-15 1980-07-24 Boehringer Mannheim Gmbh Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
IE810250L (en) * 1980-02-11 1981-08-11 Berlex Lab N-(3-phenoxy-2-hydroxypropyl) benzimidazole -1-¹alkanamines.
FR2479825A1 (fr) * 1980-04-04 1981-10-09 Fabre Sa Pierre Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments
US4472427A (en) * 1980-12-23 1984-09-18 Merck & Co., Inc. (Aralkylamino-2-OR-propoxy)heterocyclic compounds
CA1188311A (en) * 1981-05-01 1985-06-04 Edwin S. Wu Antihypertensive agents
US4473501A (en) * 1981-05-04 1984-09-25 G. D. Searle & Co. Dihydro azino isoquinolines
US4471128A (en) * 1981-09-08 1984-09-11 Ciba-Geigy Corporation 1,5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5-diols
JPS5846079A (ja) * 1981-09-12 1983-03-17 Santen Pharmaceut Co Ltd ベンゾチアゾリン環を有するエ−テル類
FR2588260B1 (fr) * 1985-10-04 1987-11-20 Adir Nouveau derive du thiochromanne, son procede de preparation et les compositions pharmaceutiques qui le contiennent
DK630987D0 (da) * 1987-12-01 1987-12-01 Ferrosan As Aryloxyphenylpropylaminer, deres fremstilling og anvendelse
US5198448A (en) * 1988-08-10 1993-03-30 Otsuka Pharmaceutical Company, Limited Cardiotonics
US5266577A (en) * 1988-08-10 1993-11-30 Otsuka Pharmaceutical Company Ltd. Method of treating congestive heart failure using carbostyril derivatives
ES2070151T3 (es) * 1988-08-10 1995-06-01 Otsuka Pharma Co Ltd Agentes cardiotonicos.
FR2746395B1 (fr) * 1996-03-22 1998-04-17 Adir Nouveaux derives d'arylethanolamine et d'aryloxypropanolamine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
ATE298739T1 (de) 1996-04-09 2005-07-15 Nps Pharma Inc Calcylitische verbindungen
US6818660B2 (en) 1996-04-09 2004-11-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
TW483881B (en) 1996-12-03 2002-04-21 Nps Pharma Inc Calcilytic compounds
US7202261B2 (en) 1996-12-03 2007-04-10 Nps Pharmaceuticals, Inc. Calcilytic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2807567A (en) * 1953-06-02 1957-09-24 Saul & Co Preparation for the treatment of allergic diseases
US2872374A (en) * 1955-02-02 1959-02-03 Nat Drug Co Muscle-relaxing tranquilizer compositions
US2984668A (en) * 1958-07-31 1961-05-16 Searle & Co 3-(2-hydroxyethyl)-4-methyl-5-phenyloxazolidine and certain esters
US3198806A (en) * 1963-08-07 1965-08-03 Dow Chemical Co 2-alkoxy-2-oxazolines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003758A1 (de) * 1978-02-09 1979-09-05 Ciba-Geigy Ag Verätherte Hydroxy-benzodiheterocyclen und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
NL139234B (nl) 1973-07-16
SE316487B (sv) 1969-10-27
GB1058822A (en) 1967-02-15
BR6461288D0 (pt) 1973-08-09
DE1493853A1 (de) 1969-06-04
DK119432B (da) 1971-01-04
ES302622A1 (es) 1965-03-16
CH468372A (de) 1969-02-15
SE316781C (sv) 1972-11-13
FR1583153A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-10-24
FR4161M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1966-05-16
NL6408650A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1965-02-01
SE316486B (sv) 1969-10-27
SE316486C (sv) 1972-11-13
SE316487C (sv) 1972-11-13
US3340266A (en) 1967-09-05
BE651032A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1965-01-27
DK111267B (da) 1968-07-15
SE316488B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1969-10-27
SE316781B (sv) 1969-11-03

Similar Documents

Publication Publication Date Title
CH472402A (de) Verfahren zur Herstellung neuer heterocyclischer Derivate
DE2024001C3 (de) Tetrahydrofurfuryloxyphenoxypropanolamine und deren pharmakologisch vertragliche Säureadditionssalze und Verfahren zu deren Herstellung sowie diese Verbindungen enthaltende Arzneimittel
CH515212A (de) Verfahren zur Herstellung von Alkanolaminderivaten
DE1493856B2 (de) 1-aryloxy-3-(n-alkylamino)-2-propanole, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
CH447151A (de) Verfahren zur Herstellung homocyclischer Verbindungen
CH622491A5 (en) Process for the preparation of novel hydroxypropylamines
DE1212090B (de) Verfahren zur Herstellung von 10-(Piperazinopropyl)-3-trifluormethyl-phenothiazinverbindungen und ihren Salzen
DE1620007C3 (de) Decahydroisochinoline
DE1285478B (de) Verfahren zur Herstellung von neuen 5, 6, 7, 8-Tetrahydropyrido-[4, 3-d]pyrimidinen
CH473800A (de) Verfahren zur Herstellung neuer heterocyclischer Derivate
DE2822473C2 (de) Alkanolaminderivate und pharmazeutische Mittel, welche diese Alkanolaminderivate enthalten
DE2638849C2 (de) 2-Aminopropionsäure-2-trifluormethylphenyl-1,1-dimethyläthylester, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2328758C2 (de) 4,4-Diphenyl-2-methyl-2-hydroxybutylamine und diese enthaltende therapeutische Zubereitungen
AT250375B (de) Verfahren zur Herstellung von neuen 3-Amino-2-hydroxypropoxyderivaten heterocyclischer Verbindungen
AT283315B (de) Verfahren zur herstellung von neuen, gemischt substituierten 1-phenoxy-3-alkylaminopropanolen-(2) und deren saeureadditionssalzen
AT246735B (de) Verfahren zur Herstellung von neuen Naphthalinderivaten und deren Salzen
AT306045B (de) Verfahren zur Herstellung von neuen Morpholinderivaten und ihren Salzen
AT202147B (de) Verfahren zur Herstellung von neuen Piperazinderivaten und von deren Salzen
AT252219B (de) Verfahren zur Herstellung von neuen Alkanolaminderivaten und deren Salzen
AT226723B (de) Verfahren zur Umwandlung von Thiaxanthenen
AT290503B (de) Verfahren zur Herstellung von neuen 1-(4'-Acylaminophenoxy)-2-hydroxy-3-aminopropanen und von deren Säureadditionssalzen
DE1543673C3 (de) Basisch substituierte Benzofuranderivate und deren pharmazeutisch verträgliche Säureadditionssalze sowie Verfahren zu deren Herstellung und Arzneimittel mit einem Gehalt dieser Verbindungen
CH518258A (de) Verfahren zur Herstellung von Naphthalinderivaten
DE1203786B (de) Verfahren zur Herstellung von Benzilsaeure-[pyrrolidyl-(2)]-methylestern und deren quaternaeren Ammoniumverbindungen
DE1142614B (de) Verfahren zur Herstellung von Benzhydrylaethern des Tropins, deren Salzen und quaternaeren Ammoniumverbindungen

Legal Events

Date Code Title Description
PL Patent ceased